| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 356246000 | Fluid containers (e.g., cells or cuvettes) | 69 |
| 20110194104 | Device and method for optical parallel analysis of a sample arrangement and corresponding manufacturing method - A device and a method for optical parallel analysis of a sample arrangement. The device includes a system of sample areas provided on and/or in a front face of the carrier substrate for receiving a sample substance; a system of detector areas provided on and/or in a back face of the carrier substrate, each detector area being assigned to a corresponding sample area; and a system of optical devices, each optical system being assigned to a corresponding sample area and being designed in such a way that it deflects light beams, which the corresponding sample area in response to an optical excitation does not emit in the direction of a detector area assigned to it, in the direction of the detector area assigned to it and/or in the direction of a detector-free area on the back face of the carrier substrate. | 08-11-2011 |
| 20090009757 | Cuvette - The present invention is to present a cuvette that is able to prevent a liquid splash and dispersion within the cuvette. The cuvette comprises: a body which is essentially cylindrical and has an opening at an upper end; and a bottom part which has a concave inner surface and is connected to a lower end of the body, wherein the inner surface of the bottom part comprises a tapered part whose inner diameter linearly decreases toward a bottom of the cuvette. | 01-08-2009 |
| 20130027695 | MICROFLUIDIC SYSTEMS WITH CHEMICAL PUMPS - A microfluidic system may include an image sensor integrated circuit containing image sensor pixels. A channel containing a fluid with particles such as cells may be formed on top of the image sensor. Flow control components may be mounted to the image sensor integrated circuit for controlling the flow of fluids through the channel. The flow control components may include a chemically powered pump. The chemical pump may include one or more chambers and a valve between the chambers. The valve may be operable to allow chemical reactants stored in the chambers to be mixed to produce gasses for generating pressure in the channel. The pressure in the channel may be used to control the flow of the fluid. As the fluid and particles flow through the channel, the image sensor pixels may be used to capture images of the particles. | 01-31-2013 |
| 20090079976 | Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and uses thereof for biomolecular interaction analysis - Photonic crystal (PC) sensors, and sensor arrays and sensing systems incorporating PC sensors are described which have integrated fluid containment and/or fluid handling structures. The PC sensors are further integrated into a sample handling device such as a microwell plate. Sensors and sensing systems of the present disclosure are capable of high throughput sensing of analytes in fluid samples, bulk refractive index detection, and label-free detection of a range of molecules, including biomolecules and therapeutic candidates. The present disclosure also provides a commercially attractive fabrication platform for making photonic crystal sensors and systems wherein an integrated fluid containment structure and a photonic crystal structure are fabricated in a single molding or imprinting processing step amendable to high throughput processing. | 03-26-2009 |
| 20120182548 | NANOFLUIDIC CELL - A flow cell is provided for the analysis and/or microscopy of liquid or gas samples on the nanometer to micron scale. The flow cell preferably includes a thin membrane that is transparent to electrons and/or photons, thereby enabling the penetration of electrons or photons into a liquid flowing through the cell. Trenches are provided on either side of the membrane, which advantageously minimize fluidic resistance outside of the window area of the cell and also enable a faster response time in response to changes in external fluidic pressure. This feature enables active feedback using pathlength sensitive probes to stabilize the fluid flow to thin streams from nanometer to micron scale thicknesses with nanometer precision. | 07-19-2012 |
| 20130050692 | PRESENTATION SYSTEM AND METHOD FOR LOW-VOLUME SOLUTION SAMPLES - A presentation system for a low-volume solution sample for use in an analysis system is provided. An adapter positions aliquots of the low-volume sample solution for measurement by the analysis system. The adapter includes a recess formed in an upper surface of the adapter for removable receipt of a sample holder that holds the aliquots of the low-volume sample solution. The sample holder is seated in the recess when the sample holder is inserted into the recess. The shape of the recess substantially conforms to at least a portion of the shape of the sample holder such that the recess maintains the sample holder in place during measurement of the aliquots. The recess also has a depth sufficient to receive the sample holder and a cover plate when the sample holder and the cover plate are inserted into the recess. | 02-28-2013 |
| 20090086198 | Micro Cuvette Assembly and Use Thereof - Relates to a micro cuvette assembly ( | 04-02-2009 |
| 20130114075 | BIOLOGIC FLUID SAMPLE ANALYSIS CARTRIDGE - A biological fluid sample analysis cartridge, analysis system, and method for analyzing a biologic fluid sample are provided. The cartridge includes a collection port, at least one channel within the cartridge in fluid communication with the collection port, a passage in fluid communication with the at least one channel, and an analysis chamber mounted on a tray. The tray is mounted relative to the cartridge and selectively positionable relative to the passage in a first position where the analysis chamber will engage a bolus of sample extending out from the passage to permit selective transfer of sample from the bolus to the analysis chamber. | 05-09-2013 |
| 20130094019 | SAMPLE CARRIER WITH LIGHT REFRACTING STRUCTURES - The invention relates to a carrier ( | 04-18-2013 |
| 20090040515 | Formats For Optical Analysis And Methods Of Manufacturing The Same - Formats for the optical testing of fluids are manufacturing using modular format components. The format components are constructed so that matching format components can be mated together to form a single format for optical testing. Formats may be manufactured using pin-and-hole construction so that pins on optical format components mate with holes on opposing format components. Optical read surfaces provided on optical format components oppose each other in a completed optical format to form a read area. | 02-12-2009 |
| 20130114076 | CARTRIDGE WITH LARGE-SCALE MANUFACTURING DESIGN - The invention relates to a cartridge ( | 05-09-2013 |
| 20090237655 | APPARATUS FOR POSITIONING A CUVETTE IN AN OPTICAL BEAM PATH OF AN OPTICAL MEASURING INSTRUMENT - An apparatus for positioning a cuvette in an optical beam path of an optical measuring instrument, with a shaft for axially inserting a cuvette, and means for pressing a cuvette against at least one wall surface of the shaft, which comprise at least one arrangement of a magnet, stationarily arranged with respect to the shaft, and a magnet movable with respect to the same, which are oriented such that the movable magnet tends to occupy a certain position with respect to the stationary magnet, in which the movable magnet engages at least partially into the shaft. | 09-24-2009 |
| 20090046282 | Flowthrough Cell of the Flowing Spectrophotomatic Analysis - In the invention, the transparent tube is used as the fluid pathway of the flowthrough cell, which not only makes sure the fluid can retain the stable laminar state and no micro-bubble existing, but also can avoid the turbulent and the micro-bubble producing the negative peak and the interference peak. Utilizing the transparent property of the pipe wall, the ektexine of both ends of the optical pathway is made to be a smooth plane and forms a single unit planar light inlet window with the pipe. There do not need to be furnished with the glass window or the quartz glass window any more. This smart design has solved the leakage and dead angle problem that has puzzled people for a long term. The invention not only simplifies the structure but also increases the precision. It produces an unexpected research finding. | 02-19-2009 |
| 20090009756 | Recognition Chip for Target Substance, and Detection Method and Device for the Same - A detection device comprising a substrate comprising a plurality of objects of which properties are changed due to the contact with a target substance, means for bringing the target substance into contact with the objects, and means for detecting a change in properties of the objects caused when the target substance is brought into contact with the objects, based on light output when the objects are irradiated with light, wherein the plurality of the objects are located in the direction in which the light for irradiation travels, and the detecting means is means for detecting the change in the properties based on the summation of light output from the plurality of the objects upon irradiation with light. | 01-08-2009 |
| 20130120747 | CELL COUNTING AND SAMPLE CHAMBER AND METHODS OF FABRICATION - The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same. | 05-16-2013 |
| 20100079749 | Inspection apparatus for biological sample - An inspection apparatus for a biological sample is herein disclosed, wherein a sample, entering a communicating space via a first opening, is sucked upward to a test area by capillarity and then sucked downward to a second opening by a siphonic action; then the sample becomes still as a result of the communicating tube principle. Hence, the present invention provides sufficient amount of biological sample for the test area and also simplifies the inspection process. | 04-01-2010 |
| 20110285990 | ANALYSIS TOOL AND MICROANALYSIS SYSTEM - In a case of generating a main body of an analysis tool and a micro flow path chip as separate components, to obtain an accurate sample analysis result and to accurately adjust fluid temperature inside the micro flow path chip without damaging an analytical light receiving section of the micro flow path chip. In main body of analysis tool ( | 11-24-2011 |
| 20110292383 | MICRO CUVETTE ASSEMBLY AND USE THEREOF - Micro cuvette assembly for examining biological samples has a first partial plate with one or more first cuvette surfaces and a second partial plate opposite the first and which also has one or more second cuvette surfaces. In an active position of the assembly, the second cuvette surfaces are arranged parallel and in register with the first cuvette surfaces and are spaced apart from the first cuvette surfaces whereby one or more micro cuvettes are formed. The first and second partial plates also have openings arranged in register with the cuvette surfaces and transparent bodies are provided as the cuvette surfaces. The first and second plates are completely penetrated by these openings and the transparent bodies are manufactured from a different material than the partial plates and span the openings close to a first surface of the partial plates. The first and second cuvette surfaces of a micro cuvette in the active position are wetted by a liquid volume which has previously been applied to one of the cuvette surfaces so that the liquid volume is held between these two cuvette surfaces. | 12-01-2011 |
| 20110292382 | SYSTEM AND METHOD FOR DETERMINING THE ASPHALTENE CONTENT OF CRUDE OIL - A system for determining the asphaltene content of crude oil includes a first optical flow cell, a first spectrometer operably associated with the first optical flow cell, and a mixer in fluid communication with the first optical flow cell. The system further includes a crude oil injection/metering device configured to receive the crude oil, the crude oil injection/metering device being in fluid communication with the first optical flow cell; a titrant injection/metering device in fluid communication with the mixer, the titrant injection/metering device configured to receive a titrant; and a filtration unit in fluid communication with the mixer. The system further includes a second optical flow cell in fluid communication with the filtration unit, and a second spectrometer operably associated with the second optical flow cell. | 12-01-2011 |
| 20110141465 | Light-Guiding Flow Cells And Analytical Devices Using The Same - A flow cell for a photometric device includes a module having a body with a distal face defining an annular channel. The body also defines an axial central passage and an axial flow channel. A second module has a body with a proximal face defining an annular channel. The second body also defines an axial flow channel in fluid communication with the first axial flow channel. A light guiding member is within the central passage for exposing a fluid in the flow channels of the modules. An assembly seals an interface between the distal and proximal faces such that the fluid does not leak from the flow channels. The assembly has a metal gasket between the distal and proximal faces, the metal gasket defining a flow path between the flow channels, a first sealing member in the first annular channel and a second sealing member in the second annular channel. | 06-16-2011 |
| 20120086938 | Analysis of an Acoustically Separated Liquid - An analyser is provided comprising a sample chamber for holding a liquid sample containing particles and an ultrasound source acoustically couplable to the sample chamber to supply resonant ultrasound energy for acoustically concentrating particles in the liquid sample in nodal planes established thereby. A probe is also provided which is adapted to supply electromagnetic energy into the sample chamber and to receive the supplied electromagnetic energy from the sample chamber at least during a time at which particles are substantially concentrated in associated nodal planes. The analyser is provided with an analysis unit in operable connection to a detector of the optical probe and is adapted to determine one or both a quantitative and a qualitative property of the liquid sample from the received electromagnetic energy. | 04-12-2012 |
| 20090153851 | CUVETTE AND METHOD FOR USING THE CUVETTE - A cuvette with at least one sealing element and two transparent elements is provided where the latter are arranged at a distance from one another and define two opposing boundary faces of a sample channel and the sealing element defines side walls of the sample channel as a result of which the sample channel is formed as a channel that is closed in the longitudinal direction with an inlet opening and an outlet opening. At least one spacer is provided which keeps the transparent elements at a distance from one another. At least one of the two transparent elements has a projection which extends towards the other transparent element and forms a boundary surface of the sample channel such that the height of the sample channel is less than the height of the at least one spacer. | 06-18-2009 |
| 20110170094 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - Cuvette, comprising at least one measuring area on each one of two arms that are pivotally connected to each other such that from a swung-apart condition, they can be swung together into a measuring position in which the two measuring areas have a distance for positioning a sample between the measuring areas, and means for positioning the two arms in a measuring position in a cuvette shaft of an optical measuring device with a sample between the two measuring areas in a beam path of the optical measuring device that crosses the cuvette shaft. | 07-14-2011 |
| 20090296083 | OPTICAL ASSAY APPARATUS AND METHODS - Optical assay apparatus and methods are provided having an optical assay cup for detecting analytes in a sample fluid. The cup's sidewall may include an optical waveguide having a detection coating on its inner surface. During use, the waveguide receives evanescent or darkfield interrogation light, interrogates at least part of cup's interior volume with it, and emits signal light as a function of the analytes. The detection coating may have fluid or non-fluid detection layers, at least part of which may form at least part of a waveguide for the interrogation light. The cup may be spun during use, such as to centrifugally-concentrate any high-density analytes towards cup's sidewall. The assay apparatus may further include an interrogation light source, a cover or spinning apparatus for the cup, and an optical detector for the signal light. | 12-03-2009 |
| 20090051913 | SENSOR DEVICE - A sensor device for detecting a substance contained in a fluid comprises first and second photonic crystal regions, first and second flow channels, an optical waveguide connected to the first and second photonic crystal regions and an optical detector for detecting the lights transmitted through the first photonic crystal region and the waveguide and transmitted through or reflected by the second photonic crystal region. | 02-26-2009 |
| 20120293797 | METHODS AND SYSTEMS FOR OPTICAL CHARACTERISATION - An optical device is described for irradiating at least one object in a medium. The optical device may be a microfluidics device, and comprises at least one integrated planar waveguide that enables providing sheet irradiation of objects in the medium. A characterization system including such an optical device and a corresponding method of characterizing an object or a fluid are described. | 11-22-2012 |
| 20100103410 | DEVICES AND METHODS FOR VISUALIZATION OF A SAMPLE IN A MICROPLATE - Disclosed herein is a microplate comprising a plurality of wells and methods and systems comprising such microplates, wherein an individual well comprises an opaque or non-transparent surface at or near the bottom of the well. The microplates herein can provide improved visualization of the process of filling a well with a liquid reagent. The microplates can be configured to perform chemical analysis, such as polymerase chain reaction (PCR) or nucleic acid detection. | 04-29-2010 |
| 20100060892 | FLOW SCHEMES FOR ENHANCED LIGHT-TARGET INTERACTION IN FLUIDIC CHANNELS - An embodiment is a fluidic channel to enhance light-target interaction. A first channel portion receives a first excitation light, an analyte flow, and a sheath flow. The analyte flow and the first excitation light are separated while in the first channel portion. The sheath flow flows on two sides or surrounds the analyte flow. A second channel portion has a first redirection structure to redirect the analyte flow by the sheath flow into the first excitation light at a first detection area. | 03-11-2010 |
| 20080239304 | Apparatus and Methods for Analyzing Samples - The present invention relates to apparatus, systems, and methods for analyzing biological samples. The apparatus, systems, and methods can involve using a vacuum source to pull microfluidic volumes through analytical equipment, such as flow cells and the like. Additionally, the invention involves using optical equipment in conjunction with the analytical equipment to analyze samples and control the operation thereof. | 10-02-2008 |
| 20100141938 | METHOD AND APPARATUS FOR DETECTION OF ANALYTES - A microfluidic detection system is provided. The system comprises a device for illuminating a microfluidic sample comprising an analyte, wherein illumination from the illuminating device is modulated on and off at a determined frequency, a gated phase-sensitive detector that detects, one or more wavelengths emitting from the analyte, at a determined frequency, and a control device that coordinates the modulating frequency of the illumination and the detecting frequency of the detector. | 06-10-2010 |
| 20110013183 | Method of Using a Flow Cell Apparatus for Visualizing Additive Deposition on a Substrate - A method of visualizing the deposition of an additive from a personal care composition onto substrates such as hair, skin mimic and fabric through the use of a flow cell device. | 01-20-2011 |
| 20090257054 | COMPACT, THERMALLY STABLE FIBER-OPTIC ARRAY MOUNTABLE TO FLOW CELL - Various embodiments of an optical system for directing light for optical measurements such laser-induced fluorescence and spectroscopic analysis are disclosed. In some embodiments, the optical system includes a thermally conductive housing and a thermoelectric controller, a plurality of optical fibers, and one or more optical elements to direct light emitted by the optical fibers to illuminate a flow cell. The housing is configured to attach to a flow cell. | 10-15-2009 |
| 20090051912 | Modular Microfluidic Flow Cytometer and Method Applications - An embodiment of the invention is directed to a portable, modular, microscope mounted, microfluidic flow cytometry system. The system includes a microscope platform having an optical input/output port, imaging optics, and a sample stage; a sample illumination source module that is removably integrated with the optical input/output port; an optics module that is removably integrated with the sample excitation light source module and the optical input/output port; a detector module that is removably integrated with the optics module and the optical input/output port; a fluidic pump module having a fluidic input and a fluidic output, a first removable fluid conduit for connecting a fluid source to the input, and a second removable fluid conduit for connecting the output to an input of a microfluidic flow module; and, a system control and programmable data processing module. The system may further incorporate a microfluidic flow module positionable on the microscope sample stage having an output removably connectable to a fluidic waste collector. Method embodiments relating to applications of the microscope-mounted microfluidic flow cytometry system are also described. | 02-26-2009 |
| 20090021729 | Photoelectric Smoke Detector - A photoelectric smoke detector is provided which is suitable for being downsized without detection capability deterioration. The present invention relates to a photoelectric smoke detector for detecting presence of smoke by utilizing a light emitting element and a light receiving element whose optical axes intersect with each other. Then the photoelectric smoke detector has: a specialized labyrinth function fulfilling part for playing only a labyrinth function of bringing air flow into an interior space thereof and preventing entry of disturbance light into the interior space; and a smoke detecting part which is provided above the specialized labyrinth function fulfilling part so that an interior space of the smoke detecting part is communicated with the interior space of the specialized labyrinth function fulfilling part, and which has the light emitting element and the light receiving element built therein and has a small hole for extracting air flow that has passed through a detection area near an intersection between the optical axes of the light emitting element and the light receiving element. | 01-22-2009 |
| 20090231576 | Method and Apparatus for Centering an Ophthalmic Lens - An ophthalmic lens (CL), e.g. a contact lens, is centered in a concave trough ( | 09-17-2009 |
| 20120105837 | Optical Cup - The present invention relates to a system for conducting the identification and quantification of micro-organisms, e.g., bacteria in biological samples. More particularly, the invention relates to a system comprising a disposable cartridge and an optical cup or cuvette having a tapered surface; wherein the walls are angled to allow for better coating and better striations of the light, an optics system including an optical reader and a thermal controller; an optical analyzer; a cooling system; and an improved spectrometer. The system may utilize the disposable cartridge in the sample processor and the optical cup or cuvette in the optical analyzer. | 05-03-2012 |
| 20100182597 | METHOD AND DEVICE FOR PRODUCING A CUVETTE AND CUVETTE PRODUCED USING SAID METHOD - A multi-part injection mold ( | 07-22-2010 |
| 20100238436 | CUVETTE - A cuvette is shaped cylindrically at one end in order to be placed in a standard microfuge and is designed to specifically remove unwanted contaminates by centrifugation. The lower part of the cuvette is shaped substantially smaller to collect liquids for direct analysis and has a shape that will conform to a variety of spectrophotometers for the measurement of the absorption of irradiation and at times the subsequent scattering of light from the liquid samples which at least in the regions of the windows or desired shape is of a transparent plastic or glass with an inner space. The upper opening of the cuvette is for filling and removing sample fluid and sample preparation in a centrifuge and the lower part projects downwards towards the floor of the measuring chamber and which comprises a smaller cross section than the upper part. A cuvette holder is designed to conform to the shape of the cuvette with an outer surface to conform to the specific measuring device. | 09-23-2010 |
| 20110058163 | Optical system for a flow cytometer with an interrogation zone - The optical system of the preferred embodiments includes a first light source that creates a first beam of a first wavelength, a first collimating element that collimates the first beam, a second light source | 03-10-2011 |
| 20100118298 | FLOW CELL FOR A FLOW CYTOMETER SYSTEM - The flow cytometer system of the preferred embodiment includes a flow cell body that functions to contain, protect, and align the components of the flow cytometer system; a flow channel, coupled to the flow cell body, that functions to conduct and focus sample fluid through an interrogation zone; and a sample injection probe, removably coupled to the flow cell body, that functions to provide a uniform flow of sample fluid to the flow channel. The flow cytometer system is preferably designed for the flow cytometer field. The flow cytometer system, however, may be alternatively used in any suitable environment and for any suitable reason. | 05-13-2010 |
| 20090116005 | FINE PARTICLE MEASURING METHOD, SUBSTRATE FOR MEASUREMENT, AND MEASURING APPARATUS - A fine particle measuring method of performing optical measurement of fine particles introduced into a plurality of sample fluidic channels provided at predetermined distances on a substrate by scanning light to the sample fluidic channels is disclosed. The method includes: sequentially irradiating the light to at least two or more reference regions provided together with the sample fluidic channels; detecting a change of optical property occurring in the light due to the reference regions; and controlling timing of emission of the light to the sample fluidic channels. | 05-07-2009 |
| 20100220322 | Cells for biochemical analysis, kit for biochemical analysis, and biochemical analyzer - The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum. | 09-02-2010 |
| 20090027666 | System and method for flow cytometry - A flow cytometry system and related method, among other things, are disclosed. In at least one embodiment, the system includes first, second, and intermediate slab formations, the last of which has formed therewithin a microfluidic channel, a lens structure arranged proximate the microfluidic channel, and a light conveying structure arranged proximate to the lens structure. The lens structure is configured to direct a portion of light to proceed between the channel and the conveying structure. The intermediate slab formation is sandwiched between the other two slab formations. In at least another embodiment, the system includes a microfluidic prism arranged proximate to the second end of a light conveying structure. Light emanating from a microfluidic channel is provided to the conveying structure at the first end, conveyed to the second end, and provided to the prism, which outputs a plurality of portions of the light at different frequencies in different directions. | 01-29-2009 |
| 20110051133 | Clinical laboratory test apparatus - A clinical laboratory testing apparatus comprises a microchip for holding a sample liquid; a rotation body for rotating the microchip; a rotation drive mechanism; a lock mechanism for locking the microchip on the rotation body; a measurement room that holds the microchip and the rotation body; a protection cover; a light source that irradiates the measuring cell of the microchip; and a light receiving unit, wherein a centrifugal separation processing of a specimen in the sample liquid is performed in the microchip. | 03-03-2011 |
| 20110255084 | BIO-SAMPLE IMAGE PICKUP DEVICE - A bio-sample image pickup device includes a light source module, a carrier, an image pickup unit, a first filter set, and a second filter set. The carrier carries the light source module and the bio-sample, and moves between a first position and a second position. The first filter set between the light source module and the image pickup unit for filtering the light emitted by the light source module, and the image pickup unit picks up the image of the bio-sample through the first filter set in the first position. The second filter set in the second position filters the light emitted by the light source module for allowing an operator to see the bio-sample in the second position through the second filter. | 10-20-2011 |
| 20100302534 | SAMPLE OBSERVATION SYSTEM AND SAMPLE OBSERVATION PROCESS - A sample observation system and a sample observation process are provided which do not need any special manipulation or treatment to limit the motion of the sample or adjust the orientation of the sample when observing the sample, and enable observation of samples simply from wider direction than ever. A sample observation system of a sample whose vertical direction is defined by gravity, wherein the system at least includes a sample holder having at least one penetrating hole for retaining a liquid containing the sample; an observation unit for observing the sample; and an angle adjusting unit for varying the angle of the observation unit to the direction of the gravity which acts on the sample in a condition in which the sample holder and the observation unit have a fixed relative angle therebetween. | 12-02-2010 |
| 20120033210 | OPTICAL DETECTION SYSTEM FOR MONITORING RTPCR REACTION - An optical detection system for monitoring real-time PCR reactions in a plurality of sample chambers with a plurality of optical units is provided. Due to a relative movement, the optical units are relative to the sample chambers, color multiplexing and space multiplexing are combined for optically detecting pathogens in a sample during the process of the PCR and delivering a quantitative result. | 02-09-2012 |
| 20080252881 | HIGH-PRESSURE CROSS-POLAR MICROSCOPY CELLS HAVING ADJUSTABLE FLUID PASSAGE AND METHODS OF USE - Apparatus and methods are described for observing samples at non-ambient temperatures and pressures. One apparatus comprises a cell body having a fluid flow-through passage and a light passage intersecting the fluid flow-through passage at an adjustable light pathlength fluid analysis region; first and second light-transmissive windows in the light passage, each window having at least one crystal axis aligned longitudinally with a longitudinal axis of the window, the windows having opposed, spaced apart, substantially flat surfaces defining the adjustable light pathlength fluid analysis region, the first window having a first window holder and the second window having a second window holder, the first window rotationally isolated from the first window holder, the second window rotationally coupled to the second window holder, the first window holder able to gradually move the first window and thus adjust the light pathlength; and first and second light polarization filters. | 10-16-2008 |
| 20110134420 | Microchip and Analyzing Apparatus - The present invention relates to a microchip | 06-09-2011 |
| 20110164245 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - A cuvette comprising at least one insert with two measuring surfaces, wherein the insert is a measurement tip, which has the two measuring surfaces on one end, which is distanced from another end of the measuring tip, and an adapter for insertion in a cuvette shaft of an optical measuring device and means of insert and adapter for releasably holding the at least one insert in the adapter with the measuring surfaces at a separation distance from each other for the positioning of a sample between the measuring surfaces in a beam path of the optical measuring device passing through the cuvette shaft. | 07-07-2011 |
| 20100073673 | CLOSED CELL FOR USE IN SPECTROPHOTOMETERS - A closed cell (1) for use in spectrophotometers, adapted to receive a liquid to be subjected to analysis and an air space or bubble to absorb pressure differentials, wherein the cell (1) includes means to retain the air space or bubble in a predetermined location in the cell. | 03-25-2010 |
| 20090174881 | OPTICAL SYSTEM FOR A FLOW CYTOMETER WITH AN INTERROGATION ZONE - The optical system of the preferred embodiments includes a first light source that creates a first beam of a first wavelength, a first collimating element that collimates the first beam, a second light source | 07-09-2009 |
| 20100026999 | METHODS OF MAKING AND USING AND APPARATUS AND DEVICES FOR PLACING LIGHT AND SAMPLE IN PHOTO-EMITTING OR ABSORBING DEVICES - The present invention relates to apparatus and devices ( | 02-04-2010 |
| 20090009758 | OPAQUE ADDITIVE TO BLOCK STRAY LIGHT IN TEFLON AF LIGHT-GUIDING FLOWCELLS - The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection. | 01-08-2009 |
| 20090262343 | INFRARED SPECTROSCOPY OF MEDIA, INCLUDING AQUEOUS - Wide band infrared spectroscopy of molecules in a variety of media is provided by apparatuses, materials and methods that allow real time spectroscopic view of molecules such as proteins in native environments. Precisely machined sample holders and algorithms are used to reduce spectroscopic effects of solvents such as water. Multiple samples can be analyzed simultaneously. Embodiments provide secondary and tertiary structure information of substances such as proteins based on molecular interactions that can be monitored and manipulated in real time. | 10-22-2009 |
| 20120038914 | METHOD AND APPARATUS FOR SORTING CELLS - A method, apparatus, and system for a sorting flow cytometer include an objective lens having an optical axis coaxially aligned with the flow path at the focal point. A controllable energy source selectively alters an analyte according to a determination of whether the analyte is in a desired sub-population. In various embodiments, one or both of the emission from the controllable energy source and/or the emission from an illumination energy source passes through the objective lens. In some embodiments in which the emission from the controllable energy source passes through the objective lens, the objective lens may focus the emission from the controllable energy source at a different point than the focal point of a signal detected from the analyte and, in particular, at a point closer to the objective lens. | 02-16-2012 |
| 20100177305 | CUVETTE FOR FLOW-TYPE PARTICLE ANALYZER - The present invention provides an optical cuvette for use in a flow-type particle analyzer, wherein the cuvette includes a removable flow tube containing a flow channel oriented coaxially. | 07-15-2010 |
| 20090147253 | MICROFLUIDIC CHIP APPARATUSES, SYSTEMS AND METHODS HAVING FLUIDIC AND FIBER OPTIC INTERCONNECTIONS - Microfluidic Chip Apparatuses, Systems, and Methods having Fluidic and Fiber Optic Interconnections. According to one embodiment, apparatuses and methods are provided for connecting a light-guiding conduit to a microfluidic channel. First and second substrates with first surfaces can be provided, wherein the first surfaces of the first and second substrates form a microfluidic channel and a connection channel when the first surfaces are positioned together, and wherein the connection channel extends from an edge of the first surface of the first or second substrate to the microfluidic channel. The apparatus and method can also include bonding the first surfaces of the first and second substrates to form the microfluidic channel and the connection channel. A light-guiding conduit can be inserted into the connection channel such that the light-guiding conduit connects to the microfluidic channel and filling an area between the light-guiding conduit and the connection channel for forming a liquid-tight seal between the light-guiding conduit and the connection channel. | 06-11-2009 |
| 20120154799 | OPTICAL ANALYZER HAVING A HOLDER FOR INSTALLATION IN A GAS-CARRYING HOLLOW SPACE - An optical analyzer, in particular an optical gas analyzer, having a holder ( | 06-21-2012 |
| 20090135415 | Optical Cavity for Gas Sensor - An optical cavity for a Non-Dispersive Infrared gas sensor has invented comprising two oppositely arranged parabolic mirrors having common focus located on the common optical axis of the parabolic mirrors, and a plane mirror arranged along the optical axis between the vertex of each of the parabolic mirrors. The NDIR gas sensor has an extended optical path to increase precision and accuracy in the measurement, and substantially increased ventilation opening size to facilitate in and out of the target gas through the optical cavity thereby decreasing the response time required for measuring the gas concentration. The sensors based on the principal of Non-Dispersive Infrared Detection is used the light-absorbing characteristic of gases to measure the amount of light absorption that occur at the specific wavelength absorbed by a target gas and calculate the target gas concentration. | 05-28-2009 |
| 20120300200 | OPTICAL MEASUREMENT DEVICE - Optical measurement devices including one or more sealing assemblies are described. The sealing assemblies are configured for use at relatively high temperatures and pressures, such as temperatures over 200 degrees F. and pressures over 10,000 psi. The sealing assemblies can include a deformable seal element surrounded on each side by a backup seal element. In some examples, the deformable seal element is formed of a material selected from a group consisting of a fluoroelastomer or polytetrafluoroethylene, and the backup seal elements are formed of a material selected from a group consisting of flexible graphite or metal foil. Optionally, at least one additional seal element functioning as an extrusion barrier can be placed on the opposite side of one or both backup seal elements from the deformable seal element. The additional seal element can be formed of polyether ether ketone or flexible graphite, for example. Additional devices and assemblies are described. | 11-29-2012 |
| 20100290041 | Monolithic Optical Flow Cells and Method of Manufacture - An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells). Manufactured from a monolithic transparent material, the improved flow cell has an internal flow channel of polygonal transverse cross-section through which prepared samples can be metered and an external envelope suited to acquisition of optical parameters from formed bodies in such samples. Preferably, such flow cell is formed by a glass-drawing process in which a relatively large glass preform having a rectilinear internal channel of a desired polygonal cross-sectional shape is heated and drawn to achieve a desired cross-sectional area of reduced size. Also disclosed are preferred methods for differentiating formed bodies using the flow cell of the invention. | 11-18-2010 |
| 20100245815 | CENTRIFUGAL DEVICE - A device consisting of a rotatable substrate ( | 09-30-2010 |
| 20110181875 | SAMPLE STORAGE - Provide a sample storage, in which barcodes and two-dimensional codes printed on the outer surface of the sample storage can be read correctly without false recognition. A storage tube | 07-28-2011 |
| 20120320375 | Apparatus for Stabilizing Mechanical, Thermal, and Optical Properties and for Reducing the Fluorescence of Biological Samples for Optical Evaluation - An apparatus is presented for stabilizing an optical, thermal, and mechanical interface between a spectroscopic and/or imaging system and a biological sample. The apparatus includes a window retainer having a retainer surface and a well. The retainer surface surrounds the well. Further, the retainer surface is substantially planar. An optical window is located in the well. The optical window comprises a first and second surface. The second surface is in contact with the window retainer. The first surface is substantially flush with the retainer surface. The apparatus further includes an attachment mechanism coupling the window retainer to the biological sample such that a fluid, gel, adhesive or elastomer interposed between the optical window and the biological sample is trapped in the well. | 12-20-2012 |
| 20100231903 | Microbubble optical resonator - An optical microresonator is configured as an optical microbubble formed along a section of an optical microcapillary. The curvature of the outer surface of the microbubble creates an optical resonator with a geometry that encourages the circulating WGMs to remain confined in the central region of the bubble, creating a high Q optical resonator. The resonator may be tuned by modifying the physical properties of the microbubble, allowing the resonator to be used as an optical filter. The resonator may also be used as a sensor or laser by introducing the material to be sensed (or the active laser material) into the microcapillary along which the microbubble is formed. | 09-16-2010 |
| 20120327404 | FLEXIBLE SAMPLE CONTAINER - The invention relates to a system for holding a fluid sample, said system comprising a transparent flexible tube for holding said fluid sample, a tube holder for holding said tube, a first flattening element, and second flattening element, wherein said first flattening element and said second flattening element may be moved relative to each other thereby changing said transparent flexible tube from a first state to a second state, where at least a first cross sectional dimension of said tube is smaller in said second state than in said first state. | 12-27-2012 |
| 20120092659 | MULTI-PARAMETER INTEGRATED CUVETTE POOL - The invention provides a multi-parameter integrated cuvette pool having a plurality of cuvette pool cells. Adjacent cuvette pool cells are connected to each other through a connecting plate. A heat generation unit is arranged in each cuvette pool cell. | 04-19-2012 |
| 20120140213 | STATIC DESALTER SIMULATOR - A small-scale static simulator for crude oil refinery desalters has an oil bath, a portion of which is made of a transparent material, a heater/circulator configured to control the temperature of the oil bath and an emulsion-forming device. The desalter simulator also includes a plurality of mixing tubes, each mixing tube having a cap member with a blending assembly configured to work with the emulsion-forming device to emulsify an oil/water mixture contained in the mixing tube. A tube-holding rack is received in the oil bath. The tube-holding rack has a plurality of parallel plates, said plates having openings forming mixing tube receiving apertures. The desalter simulator includes at least one light source positioned adjacent to the oil bath, wherein the light source comprises an under light positioned beneath the oil bath configured to direct light into each of the mixing tubes located in the tube-holding rack, wherein the light source is directed through the transparent portion to aid in visualization and testing of the demulsification process. The desalter simulator also includes a power supply, wherein the plates of the tube-holding rack are connected to the power supply to form an electric grid adjacent the mixing tubes. | 06-07-2012 |
