Class / Patent application number | Description | Number of patent applications / Date published |
356040000 | Hemoglobin concentration | 31 |
20090059203 | Apparatus For Measuring Concentration of a Specific Ingredient In-Situ - Disclosed is an apparatus for measuring the concentration of a specific ingredient in a solution. According to one embodiment of the present invention, said apparatus comprises: a signal collector for collecting a plurality of signals emitted from a target in a selected volume of the solution, and one of the signals corresponding to the selected volume; detectors for detecting the signals; and beam splitters for splitting said signals and transmitting the signals to the detectors. The present invention provides an apparatus for effectively measuring concentration in-situ without the need of extracting the solution out of its original container. | 03-05-2009 |
20090079965 | Device for Determining of Properties in a Fluid and/or Constituents Thereof - The present invention (HBX) describes a system and device design for measuring and analysis of properties in liquids with suspensions, preferably human body fluids e.g. whole blood and in the fluid existing substances and particles. By penetrating a sample of the liquid suspension with specifically calibrated light passing through a thin well defined layer of the liquid placed in a non added cuvette where the transmitted outgoing light from a measuring area is registered in a spectrophotometer adapted for the specific light and the optic geometrical system arranged for elimination of scattered light. The registered data points in the photometer is then processed in a series of steps for corrections and calculation of the values/results of the desired parameters by use of different algorithms in the microprocessor of the device for final presentation on a display, be stored in a memory and possible communication to other information receiving unit. | 03-26-2009 |
20090279071 | SPECTROSCOPIC DETECTOR AND METHOD FOR DETERMINING THE PRESENCE OF BLOOD AND BIOLOGICAL MARKER SUBSTANCES IN LIQUIDS - The invention relates to a detector for measuring scattered light in liquids having a housing, a transparent, flexible tube for transporting liquid through the housing, a light emitter, and a light detector. Two parallel surfaces are formed in the housing, between which the tube is arranged such that two opposing tube walls are formed in a planar parallel manner. The light emitter is arranged in such a way that the optical axis thereof is perpendicular to the parallel surfaces of the first tube wall, and the light detector is adjacent to the light emitter, the optical axes of the light emitter and light detector forming an angle smaller than 90°. The invention also relates to a method for detecting the presence of blood and for the quantitative determination of biological marker substances, especially bilirubin, in solution, and to a device for treating blood containing the detector. | 11-12-2009 |
20090310123 | Blood concentrate detector - A blood concentrate detector is disclosed for non-invasive, optical, detection of blood in translucent fluids, within translucent tubes, wherein the fluid is formed into a biconvex lens to 1 | 12-17-2009 |
20100020309 | BLOOD MONITORING SYSTEM - The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter. | 01-28-2010 |
20100110416 | MEASURING HEMATOCRIT AND ESTIMATING HEMOGLOBIN VALUES WITH A NON-INVASIVE, OPTICAL BLOOD MONITORING SYSTEM - An optical blood monitoring system with a ratiometric model determines hematocrit values for a hemodialysis patient, from which hemoglobin values for the patient are estimated. The ratiometric model is calibrated, normally against a cell counter, using blood from a blood bank. The blood from a blood bank is preserved in a long term preservative which is typically different than that found in clinical settings. The hematocrit value determined by the ratiometric model is scaled by scaling factor so that the estimated hemoglobin level output from the monitor consistently matches that measured in a clinical setting. The hematocrit scaling factor is substantially about 1.033 when the patient's blood sample is stored in a short term preservative ethylene diamine tetra acetic, and is substantially about 1.06 when the hematocrit is measured in the blood sample without preservative being added to the blood sample. The hemoglobin value can also be adjusted for altitude. | 05-06-2010 |
20120062869 | SPECTROSCOPIC DETECTOR AND METHOD FOR DETERMINING THE PRESENCE OF BLOOD AND BIOLOGICAL MARKER SUBSTANCES IN LIQUIDS - The invention relates to a detector for measuring scattered light in liquids having a housing, a transparent, flexible tube for transporting liquid through the housing, a light emitter, and a light detector. Two parallel surfaces are formed in the housing, between which the tube is arranged such that two opposing tube walls are formed in a planar parallel manner. The light emitter is arranged in such a way that the optical axis thereof is perpendicular to the parallel surfaces of the first tube wall, and the light detector is adjacent to the light emitter, the optical axes of the light emitter and light detector forming an angle smaller than 90°. The invention also relates to a method for detecting the presence of blood and for the quantitative determination of biological marker substances, especially bilirubin, in solution, and to a device for treating blood containing the detector. | 03-15-2012 |
20120257188 | PAPER BASED SPECTROPHOTOMETRIC DETECTION OF BLOOD HEMOGLOBIN CONCENTRATION - The present disclosure relates to the use of a paper medium to measure blood hemoglobin concentration. In certain embodiments, spectrophotometric techniques are used to measure light transmission at specified wavelengths through a paper medium containing a blood sample. The light transmission information is then used in the calculation of blood hemoglobin concentration. In certain embodiments, the paper medium may be chemically treated to lyse the blood sample prior to measurement of the light transmission information. | 10-11-2012 |
20120262705 | Measuring Volume and Constituents of Cells - A method of determining a hemoglobin content value of a red blood cell includes: (a) illuminating the cell with incident light at a plurality of illumination wavelengths; (b) obtaining at least one two-dimensional image of the cell corresponding to each illumination wavelength; (c) for each illumination wavelength, determining a mean optical density and a maximum optical density for the cell; (d) determining an area of the cell; (e) for each illumination wavelength, determining a volume of the cell; (f) for each illumination wavelength, determining an integrated optical density for the cell; and (g) determining the hemoglobin content value of the cell based on the area of the cell, the volumes of the cell corresponding to each of the illumination wavelengths, and the integrated optical densities for the cell corresponding to each of the illumination wavelengths. | 10-18-2012 |
20130070230 | APPARATUS AND METHOD FOR ESTIMATING BILIRUBIN CONCENTRATION USING REFRACTOMETRY - A bilirubin measuring apparatus includes a sample holding portion for holding at least a sample to be analyzed, a light source for directing light toward the sample holding portion, and means for determining a concentration of bilirubin in the sample based on an amount which the light is refracted while passing through the sample holding portion when at least the sample is held at the sample holding portion. Also, a method of measuring bilirubin in a sample includes holding at least the sample at a sample holding position, directing light toward the sample holding position so that the light will pass through the sample, and determining a concentration of bilirubin in the sample based on an amount which the light is refracted while passing through the sample holding position. | 03-21-2013 |
20130114069 | IMAGING VOLUMES WITH ARBITRARY GEOMETRIES IN CONTACT AND NON-CONTACT TOMOGRAPHY - A method for tomographic imaging of diffuse medium includes directing waves into a diffusive medium, solving a surface-bounded inversion problem by forward field calculations through decomposition of contributions from the multiple reflections from an arbitrary surface within the diffusive medium or outside the diffusive medium into a sum of different orders of reflection up to an arbitrary order, and using contact or non-contact measurements of waves outside said diffusive medium to generate a tomographic image. | 05-09-2013 |
20130169948 | METHOD FOR RAPID IMAGING OF BIOLOGIC FLUID SAMPLES - A method for analyzing a biologic fluid sample is provided. The method includes the steps of: a) disposing the biologic fluid sample within a chamber; b) imaging the biologic fluid sample at a first resolution, and producing first image signals representative of a low resolution image of the sample; c) analyzing the first image signals to identify one or more first characteristics of the sample, and determining a position of each first characteristic within the chamber using a map of the chamber; d) imaging a portion of the biologic fluid sample at a second resolution and producing second image signals, which portion of the sample is determined using the first characteristics and the map, and wherein the second resolution is greater than the first resolution; and e) analyzing the biologic fluid sample using the second image signals. | 07-04-2013 |
20130176551 | METHOD AND APPARATUS FOR DETECTING AND COUNTING PLATELETS INDIVIDUALLY AND IN AGGREGATE CLUMPS - A method for enumerating platelets within a blood sample is provided. The method includes the steps of: 1) depositing the sample into a sample container having an analysis chamber adapted to quiescently hold the sample for analysis, and an amount of colorant that platelets absorb and which fluoresces upon exposure to one or more predetermined first wavelengths of light; 2) imaging at least a portion of the sample disposed in the analysis chamber, including producing image signals indicative of fluorescent emissions from the platelets illuminated by first wavelengths of light; 3) identifying the platelets using the image signals; and 4) enumerating individual platelets and clumped platelets within the sample using one or more of fluorescent emissions, area, shape, and granularity. | 07-11-2013 |
20130286379 | COMBINED LIGHT SOURCE PHOTOACOUSTIC SYSTEM - A physiological monitoring system may use photoacoustic sensing to determine one or more physiological parameters of a subject. The photoacoustic system may use two light sources (e.g., a high power pulsed laser diode and a continuous wave laser diode) to generate acoustic pressure signals in a subject. One or more light sources (e.g., the high powered pulsed laser diode) may provide a high signal-to-noise ratio. The high signal-to-noise ratio signals may provide high sensitivity for physiological measurements (e.g., cardiac output and temperature measurements). The photoacoustic system may use high powered light sources in combination with other light sources to improve physiological measurements. | 10-31-2013 |
20140049770 | DETERMINING ABSORPTION COEFFICIENTS IN A PHOTOACOUSTIC SYSTEM - A physiological monitoring system may use photoacoustic sensing to determine physiological information of a subject. The photoacoustic monitoring system may use a light source, such as a modulated continuous wave laser diode, to provide a frequency modulated photonic signal (e.g., a chirp signal) to the subject. An acoustic detector may be used to detect an acoustic pressure signal from the subject. The acoustic pressure signal may include two components corresponding to two wavelengths of light in the photonic signal. A signal ratio may be calculated based on the two components. The photoacoustic monitoring system may use the signal ratio to calculate one or more absorption coefficients. The photoacoustic monitoring system may use the one or more absorption coefficients to determine additional physiological information such as hemoglobin concentration, blood oxygen saturation, and temperature. | 02-20-2014 |
20140192342 | METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF SUBSTANCES IN BODY FLUIDS - The invention relates to a method for the spectrophotometric determination of the concentration of multiple substances, preferably bilirubin, haemoglobin and lipids, in a sample of body fluid. | 07-10-2014 |
20150055121 | BLOOD ANALYSIS - The invention discloses a blood analyzing device ( | 02-26-2015 |
20150109608 | DEVICE AND METHOD FOR MEASURING HEMOGLOBIN - The present invention relates to a system for measuring the hemoglobin concentration in whole blood, wherein the system comprises: a light-radiating unit including a light source that emits two types of incident light having different wavelengths; a diffusion unit which diffuses the incident light emitted by the light-radiating unit; a cuvette-holding unit which is formed so as to hold a cuvette including a blood sample; a detection unit which detects each absorbance of the two types of incident light having different wavelengths; a processing unit which determines the hemoglobin concentration in the blood by processing the measured absorbance result; and a control unit which regulates the two types of incident light having different wavelengths in order to repeatedly/sequentially radiate same. Although the system for measuring hemoglobin in whole blood of the present invention uses a small amount of whole blood, it is possible to measure the total hemoglobin concentration in an accurate and reliable manner. The system of the present invention aligns the paths of two types of incident light having different wavelengths passing through a microcuvette by using a diffuser plate so as to easily align a light source and increase the reliability of the results. Also, the system of the present invention uses two wavelengths so as to rapidly and accurately measure the total amount of hemoglobin, including oxidized and reduced hemoglobin. | 04-23-2015 |
20160091423 | APPARATUS AND METHOD FOR MEASURING HEMOGLOBIN CONCENTRATION WITHIN BLOOD USING LIGHT AND HEAT LIGHT SCATTERING - An apparatus for measuring a hemoglobin concentration includes a reference light source unit, a light and heat light source unit configured to emit a light and heat beam for generating a light and heat effect, an accommodation unit configured to accommodate obtained blood samples, an image acquisition unit configured to write a primary pattern formed after the reference beam emitted by the reference light source unit is incident on the accommodation unit and a secondary pattern formed under an influence of a light and heat effect after the light and heat beam emitted by the light and heat light source unit is incident on the accommodation unit, and a concentration calculation unit electrically connected to the image acquisition unit and configured to calculate a hemoglobin concentration based on a difference between the primary pattern and the secondary pattern. | 03-31-2016 |
20160091484 | BLOOD ANALYZER AND BLOOD ANALYZING METHOD - A blood analyzer comprises a flow cell, a first light source, a second light source, a first light receiving part, a second light receiving part, and a processing unit. The processing unit obtains values related to the number of red blood cells, the number of white blood cells, and hemoglobin based on a first scattered light information based on the signals output from the first light receiving part, and a second scattered light information based on the signals output from the second light receiving part. | 03-31-2016 |
20160109372 | SYSTEMS AND METHODS FOR IMAGING FLUID SAMPLES - Systems and methods for imaging a plurality of blood fluid samples or other types of samples include processing at least a portion of a sample to enhance imageability of certain particles in that portion and subsequently imaging the sample portion. In some instances, processing and imaging of various samples may be staged in a manner to optimize throughput of the system or method. | 04-21-2016 |
20160178573 | COMBINATION OPTICAL HEMOGLOBIN AND ELECTROCHEMICAL LEAD ASSAY | 06-23-2016 |
356041000 | Oximeters | 8 |
20080297764 | Sensor for determining body parameters - A sensor for measuring at least one body parameter, particularly blood and/or tissue parameters, is used for carrying out the measurements of electromagnetic radiation in the transmission or reflection methods, wherein the sensor uses at least one LED as a source of electromagnetic radiation. At least one photodetector is used as the receiving element. At least one LED is used in a non-invasive measurement of the parameters for ensuring a sufficiently high residual intensity of the radiation received by the photodetector and transmitted or reflected by the blood and/or tissue, wherein the LED has a light intensity of at least 200 millicandela and/or a light yield of at least 2 lumen/watt. | 12-04-2008 |
20090115997 | MEASUREMENT SYSTEMS AND METHODS FOR OXYGENATED HEMOGLOBIN SATURATION LEVEL - Measurement system and methods for measuring oxygenated hemoglobin saturation level are provided. Light is transmitted to test blood and a reference mirror. The reference mirror provides a first reflected light beam, and backscattered light from different depths of the test blood generates a second reflected light beam. An interfered light signal is generated by light interference of the first and second reflected light beams. According to the interfered light signal, a first light decay constant for a first light wavelength range and a second light decay constant for a second light wavelength range are obtained according to the interfered light signal. A decay ratio of the first light decay constant to the second light decay constant is obtained. Oxygenated hemoglobin saturation level of the test blood is obtained according to the decay ratio. | 05-07-2009 |
20090168050 | Optical Sensor System And Method - The disclosed optical component may include an optical device and an overmold. The optical device may be configured to transmit or receive one or more wavelengths of light. The overmold may be disposed about the entirety of the optical device and may include a material transparent to the one or more wavelengths of light. A method of manufacturing a sensor may include overmolding an optical device with an overmold material that is transparent to a wavelength of light emitted or received by the optical device. The method may also include disposing the overmolded optical device proximate a sensor frame. The method may also include overmolding the sensor frame and the overmolded optical sensing device with a second overmold material. Further, the second overmold material may not block a portion of the overmolded optical device such that light can be emitted or received by the optical device without interference from the second overmold material. | 07-02-2009 |
20090323049 | Systems And Methods For A Wavelet Transform Viewer - Techniques for the display of a signal with a wavelet transform of that signal in a wavelet transform viewer are disclosed, according to embodiments. According to embodiments, the wavelet transform viewer can display a plot of physiological signals such as a photoplethysmograph (PPG) signal. A portion of the plot of the signal can be selected. A wavelet transform the selected portion of the signal can be calculated and a wavelet plot of the tranformed signal can be displayed simultaneously with that signal. A plot of the selected portion of the signal can also be simultaneously displayed with both the plot of the signal and the wavelet plot. | 12-31-2009 |
20120113411 | OPTICAL FIBER SENSORS - The present disclosure describes the use and the manufacture of a fiber optic sensor having an angled terminal portion of a fiber optic element. In one embodiment, an optical fiber is cut at an angle and a portion of the fiber's jacket is removed near the angle so that the cladding is exposed. Light may then travel through the fiber, reflect off the angled portion, and emit through the exposed cladding into a patient. Light may also be collected from the patient using the same or a different fiber optic element having an angled terminal portion. In one embodiment, the emitted light can then be collected and analyzed to derive various physiological parameters. In certain embodiments, the fiber optic sensor may be used in environments where metallic and/or electronic sensors are not suitable. | 05-10-2012 |
20120120384 | Sensor Clip Assembly for an Optical Monitoring System - A sensor clip assembly for an optical blood monitoring system includes a circuit board with a microprocessor that is programmed with a ratiometric model to calculate hematocrit and/or oxygen saturation levels of a patient. | 05-17-2012 |
20120154789 | Sensor clip assembly for an optical monitoring system - Systems and sensor clip assemblies for optically monitoring blood flowing through a blood chamber are provided. A sensor clip assembly includes emitters and photodetectors positioned on opposing arms, a signal conditioning circuit for conditioning raw analog signals generated by the photodetectors while the sensor clip assembly is fastened to a blood chamber, and an analog-to-digital converter for converting the conditioned analog signals to raw digital data. The sensor clip assembly may output the raw digital data to an external device and receive synchronized control signals from the external device, or the sensor clip assembly may include a microcontroller for performing calculations on the raw digital data and providing synchronized control signals internally. Parameters of blood flowing through the blood chamber such as hematocrit, oxygen saturation, and change in blood volume may be calculated from the raw digital data derived from the raw analog signals generated by the photodetectors. | 06-21-2012 |
20160158427 | SELF CALIBRATING BLOOD CHAMBER - An optical blood monitoring system and corresponding method avoid the need to obtain a precise intensity value of the light impinging upon the measured blood layer during the analysis. The system is operated to determine at least two optical measurements through blood layers of different thickness but otherwise substantially identical systems. Due to the equivalence of the systems, the two measurements can be compared so that the bulk extinction coefficient of the blood can be calculated based only on the known blood layer thicknesses and the two measurements. Reliable measurements of various blood parameters can thereby be determined without certain calibration steps. | 06-09-2016 |
356042000 | Standards | 1 |
20150029492 | MEASUREMENT OF TOTAL HEMOGLOBIN IN WHOLE BLOOD - A method for determining total hemoglobin concentration in a blood sample comprising spectrophotometric analysis of a blood sample at two wavelengths and determining a ratio of the detected radiation at a first wavelength to the detected radiation at a second wavelength; and determining a concentration of total hemoglobin in the blood sample based on the ratio. | 01-29-2015 |