Class / Patent application number | Description | Number of patent applications / Date published |
250302000 | RADIATION TRACER METHODS | 7 |
20080224034 | System and Method for Locating One or More Persons - An apparatus ( | 09-18-2008 |
20100096548 | SPECTRAL CALIBRATION OF FLUORESCENT POLYNUCLEOTIDE SEPARATION APPARATUS - The invention relates to methods, compositions, and systems for calibrating a fluorescent polynucleotide separation apparatus. One aspect of the invention is multiple color calibration standards and their use. A multiple color calibration standard is a mixture of at least two polynucleotides of different length, wherein each of the polynucleotides is labeled with a spectrally distinct fluorescent dye. Another aspect of the invention is to produce total emission temporal profiles of multiple color calibration standards for use in calibrating fluorescent polynucleotide separation apparatus. The peaks corresponding to the fluorescently labeled polynucleotides in the total emission temporal profile may be detected using a peak detector that is driven by changes in the slopes of the total emission temporal profile. Calibration of fluorescent polynucleotide separation apparatus, with various embodiments of the methods of the invention, includes the step of identification of the labeled polynucleotides of the multiple color calibration standards. The process of spectral calibration of a fluorescent polynucleotide separation apparatus using a multiple color calibration standard may include the step of the estimating (extracting) of the dyes' reference spectra, using information from the peak detection process performed on the total emission temporal profile. Other aspects of the invention include systems for separating and detecting fluorescently labeled polynucleotides, wherein the system is designed for spectral calibration in accordance with the subject calibration methods employing multiple color calibration standards. Another aspect of the invention is methods and compositions for detecting the flow of electrical current through a separation channel of a fluorescent polynucleotide separation apparatus. These methods and compositions employ monitoring dyes. Monitoring dyes are fluorescent dyes that are spectrally distinct from the dye on the polynucleotide intended to convey genetic information, e.g., fluorescent polynucleotide sequencing reaction products. | 04-22-2010 |
20100258718 | Fragmented taggant coding system and method with application to ammunition tagging - The present invention relates to identification tagging, and is specifically directed to identification tagging of ammunition. An isotopic taggant is deposited in a layer at the interface between the primer and the propellant so that, as the ammunition is fired, the taggant is dispersed throughout the propellant. The taggant is thus contained in the gunshot residue formed during the firing, and can be read by analysis of residue particles. Alternatively, the taggant may be deposited in a layer under the primer reactants, or in pellets which are easily destroyed by the chemical reactions involved in firing the ammunition, again dispersing the taggant throughout the propellant and the gunshot residue. Non-isotopic chemical taggants may also be employed if they are encoded so as to minimize the possibility of the information being destroyed or improperly read after the taggants are exposed to the chemical reactions in firing the ammunition. This is accomplished by employing a binary coding system and a system of authentication tags. Particulate taggants may also be used. The required large number of unique identification tags are obtained by using a fragmented coding system wherein each particle encodes only a portion of the serial number. | 10-14-2010 |
250303000 | Radioactive tracer methods | 4 |
20110284742 | DETECTION OF Kr-85 GAMMA RAYS FOR POSITIVE VERIFICATION OF MASS IN PRESSURIZED BOTTLES - A Kr-85 tracer gas is mixed with the carrier gas in a pressurized bottle. External detection of the gamma rays that penetrate through the walls of the bottle provides a non-invasive technique for the positive verification of mass inside the bottle over the lifetime of the bottle | 11-24-2011 |
20160084971 | SYSTEMS AND METHODS FOR POLARIZED NUCLEAR IMAGING AND SPECTROSCOPY - Some aspects of the present disclosure relate to systems and methods for examining a subject. In one embodiment, a method includes polarizing nuclei of a radioactive substance such that the spins of the nuclei are oriented in a specific direction, to generate a polarized radioactive tracer with anisotropic gamma ray emission probability. The method also includes introducing the tracer into a subject. The method further includes applying radio frequency oscillating (RF) magnetic fields and/or spatially varying magnetic fields to the tracer that are configured to manipulate the orientation of the spins such as to manipulate the directional dependence of gamma ray emission from the tracer. The method further includes detecting gamma rays from the gamma ray emission, and obtaining, based on the detected gamma rays and properties associated with the anisotropic gamma ray emission, imaging data and/or spectroscopic data associated with the tracer in the subject. | 03-24-2016 |
20160161315 | ISOTOPE SPECIFIC ARBITRARY MATERIAL FLOW METER - A laser-based mono-energetic gamma-ray source is used to provide non-destructive and non-intrusive, quantitative determination of the absolute amount of a specific isotope contained within pipe as part of a moving fluid or quasi-fluid material stream. | 06-09-2016 |
20220133254 | SYSTEMS AND METHODS FOR THREE-DIMENSIONAL IMAGING - Disclosed herein is a method of imaging a tracer in a body region of an organism, the body region comprising L imaging regions (imaging regions (i), i=1, . . . ,L), wherein L is an integer greater than 1, the method comprising: for i=1, . . . ,L, causing the tracer in essentially only the imaging region (i) to emit characteristic X-ray photons (i); for i=1, . . . ,L, capturing a region image (i) of the tracer in essentially only the imaging region (i) with the characteristic X-ray photons (i); and determining a three-dimensional (3D) distribution of the tracer in the body region based on the region images (i), i=1, . . . ,L. | 05-05-2022 |