Entries |
Document | Title | Date |
20080203021 | SEPARATION - The invention refers to method for selectively binding and separating at least one component from whole blood or a body fluid, whereby the blood or body fluid is allowed to pass through a rigid integral separation matrix without being excluded therefrom. The matrix has a porous structure with a pore size ranging from 5 micron to 500 micron as well as an active surface ranging from 0.5 cm | 08-28-2008 |
20080203022 | Systems and Methods Using Multiple Solvents for the Removal of Lipids from Fluids - This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy. | 08-28-2008 |
20080217246 | ELECTROCHEMICAL DETECTION SYSTEM - An electrochemical detection system having a disposable cartridge capable of performing a plurality of assay protocols is disclosed. The cartridge includes a blister pack for the long-term storage and controlled release of multiple reagents. The blister pack is bonded to and operatively associated with a fluidic backbone for providing the fluid pathways, storage capacity, and fluid control functions for performing multiple assay protocols. The cartridge further includes a plurality of sensors having a multiple electrode arrangement in operative association with a respective flow cell defined by the fluidic backbone. After the user has transferred a sample into the cartridge and engaged the cartridge to the reader, the reader operatively interfaces with the cartridge such that different assay protocols may be simultaneously performed in isolation from one another inside the cartridge. The reader may be one of many readers that operatively communicate data to a remote server for processing. | 09-11-2008 |
20080230475 | Filter for the Removal of Substances from Blood Products - A filter device for the depletion of the leukocyte content from blood products comprising: a porous element comprising at least one fibrous web having a pore size suitable for leukocyte removal (possibly the range for the pore size should be defined), said web comprising fibres of a hydrophobic polymer coated with a hydrophilic polymer suitable to enhance the CWST of said hydrophobic polymer, characterised in that said web further includes adsorbent particles having a mean diameter lower than 30 μm, said particles being bonded to said fibres by means of said hydrophilic polymer coating said fibres. | 09-25-2008 |
20080251459 | BIOLOGICAL FLUID FILTRATION SYSTEMS AND METHODS - Biological fluid filtration systems and methods are provided for the treatment of air within the system. A filtration system includes a pre-filter container joined to an expandable post-filter container by a filter line having a filter. The post-filter container has a relatively smaller maximum volume, such that it limits the amount of gas in the post-filter container during and after filtration of a biological fluid, thereby improving removal of air from the post-filter container. | 10-16-2008 |
20090032468 | Methods for Removal of Lipids from Fluids - This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored. | 02-05-2009 |
20090139931 | SYSTEMS AND METHODS OF MICROFLUIDIC MEMBRANELESS EXCHANGE USING FILTRATION OF EXTRACTION OUTLET STREAMS - A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration. | 06-04-2009 |
20100078384 | APPARATUS AND METHOD FOR SEPARATION OF PARTICLES SUSPENDED IN A LIQUID FROM THE LIQUID IN WHICH THEY ARE SUSPENDED - A method for separating, or removing, particulate material, e.g., blood cells, from a sample of fluid, e.g., whole blood of a patient, in which the particulate material is suspended. In the case of separating blood cells from blood plasma or blood serum, the resulting samples of blood plasma or blood serum can be used for in vitro diagnostic applications. In normal practice, a whole blood sample of a patient are provided and then introduced into an apparatus that contains a flow channel. An acoustic field, which contains acoustic standing waves from external ultrasonic transducers, is located within the flow channel. Laminar flow is maintained in the flow channel. Blood cells and platelets are separated from blood plasma or blood serum at the end of the flow channel and collected. The method described herein allows fluid components to differentially migrate to areas of preferred acoustic interaction. The parameters that affect separation of particles are size, density, compressibility of the particles, and the fluid surrounding the particles. | 04-01-2010 |
20100170849 | BUFFERED COMPOSITIONS FOR DIALYSIS - Acid concentrates, and dialysate compositions prepared therefrom, contain citric acid and an effective amount of a buffering agent selected from acetate and/or lactate. The buffering agent allows a physiologically acceptable amount of citrate to maintain the desired pH of the dialysate. | 07-08-2010 |
20100282681 | Biological Fluid Filtration Apparatus - Biological fluid filtration systems including biological fluid filtration devices capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system includes a means to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device. Both single sided and double sided biological fluid filtration devices are disclosed, including double sided biological fluid filtration devices with a solid partition wall with a first independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining means include vent filtration devices, diaphragm draining devices, and biological fluid filtration devices that include an integral diaphragm. The biological fluid filtration devices include low hold-up volume filter underdrains that purge in excess of 95% of the initial air in the device before liquid begins to flow from the outlet, thereby allowing the devices to be used in bed side applications. Variable surface area biological fluid filtration devices are disclosed that further reduce hold-up volume. | 11-11-2010 |
20110108482 | DIALYZER WITH DUAL SAFETY VALVES - The present invention discloses a novel method, device, apparatus, or system, which includes a dialyzer casing having a dialysate inlet and outlet with check valves disposed adjacent thereto, allowing the dialysate to flow only in one direction. The casing also has a fluid inlet and outlet for body fluid to be treated flowing therethrough. A first check valve is arranged between the dialysate inlet and a dialysate entry line leading to the dialyzer casing, while a second check valve is arranged between the dialysate outlet and a dialysate exit line departing from the dialyzer casing. | 05-12-2011 |
20110174733 | FILTER SYSTEM FOR EXTRACORPOREAL DEPLETION OF ACTIVATED POLYMORPHONUCLEAR LEUKOCYTES (PMNs) - The invention relates to a filter system for removing activated PMNs and mediators which are responsible for the activation thereof, and optionally mediators which are simultaneously, but independently of activated PMNs, responsible for a state of illness from body fluids, process for production thereof and use thereof. The inventive filter system for continuous removal of activated PMNs from blood consists of molecules which recognize and bind activated PMNs, molecules which recognize and bind PMN-activating mediators, molecules which recognize and bind C3a and/or C5a, biocompatible surfaces (carriers) on which the molecules a., b. and c. are bound covalently or adsorptively, a casing for accommodating the active carriers, valves and tubes. The field of use of the invention is medicine. | 07-21-2011 |
20110186517 | Dialysis machine, in particular peritoneal dialysis machine - The present invention relates to a dialysis machine, in particular a peritoneal dialysis machine, to which a fluid system having a multi-chamber container with at least two chambers with individual solutions separated by a partition arrangement to be opened mechanically can be coupled having a controller and at least one sensor for the determination of a measured variable in the fluid system, wherein the controller has an apparatus for the automatic checking of the proper opening of the partition arrangement of the multi-chamber container which automatically checks the proper opening of the partition arrangement of a multi-chamber container of a fluid system coupled to the dialysis machine with reference to the measured variable determined by the sensor. | 08-04-2011 |
20110309019 | APPARATUS FOR THE EXTRACORPOREAL TREATMENT OF BLOOD - Apparatus and methods for the extracorporeal treatment of blood are described. The apparatus includes a dialyzer which is separated into a first and second chamber by a semipermeable membrane, wherein the first chamber is disposed in a dialysis fluid path and the second chamber can be connected to the blood circulation of a patient by way of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a measuring device disposed within the discharge for determining the absorption of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source for substantially monochromatic electromagnetic radiation, and a detector system for detecting the intensity of the electromagnetic radiation, wherein means are provided to compensate for changes that occur in the intensity of the electromagnetic radiation of the radiation source and/or the sensitivity of the detector system. | 12-22-2011 |
20120103901 | SYSTEMS AND METHODS OF MICROFLUIDIC MEMBRANELESS EXCHANGE USING FILTRATION OF EXTRACTION OUTLET STREAMS - A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids is passed through a filter upon exiting the channel and is recycled through a secondary processor which changes the fluid's properties. The recycled fluid is reused for further exchange. The filter excludes blood cells from the recycled fluid and prevents or limits clogging of the filter. The secondary processor removes metabolic waste and water by diafiltration. | 05-03-2012 |
20120118825 | BLOOD FILTER AND METHOD FOR FILTERING BLOOD - The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe. | 05-17-2012 |
20120168377 | Integrated Measurement System for Use with Surgical Fluid Salvage Containers - A reservoir for use with a blood collection system includes a housing, a pre-filter, and a spring mechanism. The housing defines a cavity and has an inlet for receiving fluid from a source. The pre-filter is located within the cavity, removes particulates contained within the fluid, and allows the fluid to pass through the pre-filter. The spring mechanism is connected to the pre-filter and allows the pre-filter to travel within the cavity as the pre-filter collects particulates. | 07-05-2012 |
20130327712 | FILTER DEVICE - Devices, systems, and methods for obtaining one or more desired fluid components, using a back-flushable filter device comprising a filter and at least one diffusing plate, are disclosed. | 12-12-2013 |
20140284275 | ZERO EMISSION DIALYSIS CLINIC - The present invention provides a zero-emission dialysis clinic including a building envelope, daylight concept, lighting concept, mechanical ventilation ( | 09-25-2014 |