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For oxygen or oxygen containing compound (except water)

Subclass of:

205 - Electrolysis: processes, compositions used therein, and methods of preparing the compositions

205775000 - ELECTROLYTIC ANALYSIS OR TESTING (PROCESS AND ELECTROLYTE COMPOSITION)

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
205785500 Gaseous oxygen or oxygen containing compound 18
205783500 Using solid electrolyte 12
205782500 Using semipermeable membrane 5
20110284394Portable Electrochemical Multiphase Microreactor for Sensing Trace Chemical Vapors - A multiphase microreactor includes gas and liquid microchannels separated by a nanoporous membrane. Rapid mass transfer of gas samples into the liquid electrolyte allows the microchannel/membrane assembly to be used as a fast and sensitive gas sensor. When the oxime chemistry is adapted into the microchannel sensor, the microchannel sensor selectively responds to organophosphates and organophosphate simulants. In addition, a double microchannel design may be used to reduce voltage drift and incorporate a reference electrode into the sensor assembly. Methods of detecting organophosphates are also disclosed.11-24-2011
20100264042METHOD OF MONITORING GAS COMPOSITION - A method of determining the general or a specific condition of a subject is disclosed, the method comprising measuring the concentration of each of a plurality of components in a single sample of the gas stream exhaled by the subject; and generating information regarding the concentration of each of the plurality of components such that the concentrations of the components are directly comparable. The method is particularly suitable for assessing the condition of the respiratory system of a subject. The method preferably employs electrochemical sensors to measure the concentration of the target components in the exhaled gas stream.10-21-2010
20120125790ELECTROCHEMICAL SENSOR FOR MEASURING THE OXYGEN PARTIAL PRESSURE IN A PROCESS FLUID AND A METHOD FOR TESTING ITS FUNCTION - An electrochemical sensor for measuring the oxygen partial pressure in a process fluid, comprises 05-24-2012
20110180426Modulating Polarization Voltage of Amperometric Sensors - The service life of amperometric electrochemical oxygen sensors is increased by operating the electrodes of such sensors at a polarization voltage suitable for measuring the oxygen content of samples only during calibration or when measuring such samples and thereafter modulating the polarization voltage to a lower voltage such that substantially no electrical current is produced by the electrodes.07-28-2011
20120168322Oxygen Sensor with a Microporous Electrolyte Layer and Partially Open Cover Membrane - The present invention concerns an electrochemical sensor for determining oxygen dissolved in an aqueous measuring medium, a process for its production as well as a method for determining oxygen dissolved in an aqueous measuring medium using the electrochemical sensor.07-05-2012
205786000 Using electrode containing precious metal or free carbon 4
20100000883Sensor Comprising Conducting Polymer Materials - A sensor comprises a substrate having nanoparticles of a conducting polymer such as polyanaline printed thereon. Also described is a printing composition for printing onto a substrate, the composition comprising nanoparticles of a conducting polymer such as polyanaline.01-07-2010
20100294672Method and apparatus for determining information concerning presence of constituents of a liquid sample with oxygen demand - In a method and apparatus for determining information concerning the presence of ingredients with oxygen demand in a liquid sample, especially for determining the chemical oxygen demand of a liquid sample, especially a water, or wastewater, sample, by means of electrochemical oxidation of ingredients of the liquid sample, oxidation of ingredients of the liquid sample occurs on a boron doped, diamond electrode.11-25-2010
20130180869ELECTROCHEMICAL TEST STRIP AND METHOD FOR TESTING A SAMPLE USING THE SAME - An electrochemical test strip is provided, including a substrate, an electrode structure and an insulative film. The electrode structure is formed on the substrate, including a first electrode and a second electrode. The second electrode includes a first end, a second end, an extension portion, and a bent portion. The extension portion connects the first end with the bent portion, and the bent portion is connected to the second end. The extension portion and the first electrode define a space therebetween for receiving the bent portion. The insulative film covers at least a part of the electrode structure and forms an opening. A sample fluid enters the electrochemical test strip through the opening, and the sample fluid sequentially contacts the first electrode and the second electrode.07-18-2013
20120043226Blood glucose sensing - An oxidative peak in a cathodic scan is observed in the cyclic voltammetry of glucose at gold electrodes, its peak current density being proportional to glucose concentration in a wide potential range. The application of this phenomenon in blood glucose sensing has been hindered by the presence of inhibitors: the most problematic are chlorides due to their high concentration and difficult separation from glucose. The present invention provides a solution to this problem involving a three electrode, four step pulsed electrochemical detection technique.02-23-2012
Entries
DocumentTitleDate
20090211922ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, APPARATUS FOR ELECTROCHEMICAL MEASUREMENTS HAVING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, AND METHOD OF THE QUANTITATIVE DETERMINATION OF A TARGET SUBSTANCE USING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS - An electrode plate for electrochemical measurements capable of measuring the concentration of a target substance included in a sample solution with favorable accuracy and high sensitivity is provided08-27-2009
20130043141SYSTEM AND METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A SAMPLE FLUID - The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error.02-21-2013
20130043142METHOD AND APPARATUS FOR MEASURING OXIDATION-REDUCTION POTENTIAL - Methods and systems for measuring the oxidation-reduction potential of a fluid sample are provided. The system includes a test strip with a sample chamber adapted to receive a fluid sample. The sample chamber can be associated with a filter membrane. The test strip also includes a reference cell. The oxidation-reduction potential of a fluid sample placed in the sample chamber can be read by a readout device interconnected to a test lead that is in electrical contact with the sample chamber, and a reference lead that is in electrical contact with the reference cell. Electrical contact between a fluid sample placed in the sample chamber and the reference cell can be established by a bridge. The oxidation-reduction potential may be read as an electrical potential between the test lead and the reference lead of the test strip.02-21-2013
20110203942SENSOR CHIP, BIOSENSOR SYSTEM, METHOD FOR MEASURING TEMPERATURE OF BIOLOGICAL SAMPLE, METHOD FOR MEASURING TEMPERATURE OF BLOOD SAMPLE, AND METHOD FOR MEASURING CONCENTRATION OF ANALYTE IN BLOOD SAMPLE - A sensor chip (08-25-2011
20100012527Small Volume In Vitro Analyte Sensor - A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable.01-21-2010
20130075278Preparation and Maintenance of Sensors - Apparatus and methods are described for preparing, maintaining, and stabilizing sensors. The apparatus and methods for preparing sensors for use are utilized in advance of the sensor being removed from a sealed, sterilized package. The apparatus include packaging materials having electrical circuits capable of stabilizing a sensor to prepare the sensor for use. The methods for preparing a sensor for use includes methods of providing a solution to a sterilized packaging that contains a sensor connected to a sensor activating circuit, activating the circuit, and allowing the sensor to stabilize. These methods can be performed without compromising the packaging. The apparatus for stabilizing a sensor that is in use include a circuit connectable to the sensor that provides a signal to the sensor that prevents the sensor from becoming destabilized when disconnected from a monitoring device.03-28-2013
20130032493Sensor Arrangement for Continuously Monitoring Analytes in a Biological Fluid - A sensor for continuous detection of one or more analytes in a liquid flow, comprising an array of electrodes together forming an essentially planar sensing surface and a flow distributor with a flow inlet a flow channel and a flow outlet in order to establish a liquid flow of analytes along the sensing surface. The flow inlet and the flow outlet are located in a plane different to the plane of the sensing surface. The array of electrodes is arranged so that, in the direction from the flow inlet to the flow outlet, the array of electrodes consecutively comprises a first blank electrode, at least one measuring electrode, a second blank electrode, at least one measuring electrode and optionally a third blank electrode.02-07-2013
20120234699BIOSENSOR AND METHOD FOR DETERMINING AN ANALYTE CONCENTRATION - A method of determining an analyte concentration employs a biosensor that includes a molecularly imprinted polymer film formed on a metal layer. The biosensor is connected to a charge/discharge circuit and charged and discharged during exposure to a solution containing an analyte. Voltage values during discharge are measured, and a characteristic parameter of the voltage values, which is associated with a concentration of the analyte detected by the biosensor, is determined. An unknown concentration of the analyte is determined by comparing the characteristic parameter to reference data representing a relation between known concentration of the analyte and the characteristic parameter of the biosensor. A biosensor, such as an anesthetic biosensor, is also disclosed.09-20-2012
20100264041CONVERTER FOR USE WITH SENSING DEVICES - A system and method are disclosed for utilizing sensors with existing devices. An interface module is used in combination with a newer sensor, such as a fluorescence oxygen sensor, and an older legacy device. The older legacy device supplies a polarizing voltage, and anticipates a measured current of between 0 and 100 nA. The newer sensor requires no polarizing voltage and delivers an output of 0-10 volts in one embodiment, and 4-20 mA in another embodiment. The interface module receives the output from the sensor, and converts it into a useable signal to the legacy device. In another embodiment, the interface module comprises a number of outputs, such that both legacy devices and newer devices can be in communication with the sensor simultaneously. The interface module can be used in conjunction with a reactor chamber or other pharmaceutical process.10-21-2010
20120097554ANALYTE SENSORS COMPRISING ELECTRODES HAVING SELECTED ELECTROCHEMICAL AND MECHANICAL PROPERTIES - Embodiments of the invention disclosed herein comprise amperometric glucose sensor systems that include multiple working electrodes having different material properties as well as algorithms and other elements designed for use with such systems. While embodiments of the innovation can be used in a number of contexts, typical embodiments of the invention include glucose sensors used to facilitate the management of diabetes.04-26-2012
20110168575SAMPLE CHARACTERIZATION BASED ON AC MEASUREMENT METHODS - One aspect concerns a technique for detecting analyte concentrations, such as glucose concentrations, in blood or other bodily fluids. This technique utilizes an electrochemical test strip that includes a mediator system that generates a linear faradic response at relatively low applied potential differences. An alternating current excitation signal is applied to blood in the test strip. The alternating current excitation signal includes a low frequency signal and a high frequency signal that has a higher frequency than the low frequency signal. The glucose concentration is determined by measuring a low frequency response to the low frequency signal, measuring a high frequency response to the high frequency signal, estimating the glucose concentration based on the low frequency response, and correcting the glucose concentration for one or more error-causing variables based on the high frequency response.07-14-2011
20080245675METHOD OF ALTERING THE SENSITIVITY AND/OR SELECTIVITY OF A CHEMIRESISTOR SENSOR - The present invention relates to a method of altering the sensitivity and/or selectivity of a chemiresistor sensor, to a sensor and a sensor array produced by such method.10-09-2008
20110198240Sensors and Methods for Detecting Organic Carbonyl Species - A method for detecting an organic carbonyl species involves exposing a metal oxide-free film of a polyaniline to an environment suspected of containing an organic carbonyl species, detecting a change in electrical conductivity and/or an optical or luminescent property of the polyaniline, and, correlating the change in electrical conductivity and/or optical or luminescent property to a presence of the organic carbonyl species in the environment. Further, sensors for organic carbonyl species are disclosed having a metal oxide-free film of a polyaniline supported on an electrically insulating substrate. The method and sensors provide a good balance between response time and sensitivity, being considerably faster than metal oxide and metal oxide/polymer based sensors, while having greater sensitivity than other polymer-based sensors.08-18-2011
20120067743METHOD OF CORRECTING FOR OXYGEN EFFECT ON TEST SENSORS - An electrochemical test sensor is adapted to measure glucose and correct for the oxygen effect in a fluid sample. The test sensor comprises a base, first and second working electrodes, and a counter electrode. The first working electrode includes glucose oxidase, a mediator and peroxidase. The second working electrode includes glucose oxidase and the mediator. The first working electrode, the second working electrode and the counter electrode are located on the base. In other embodiments, an electrochemical test sensor is adapted to measure cholesterol, lactate, pyruvate or xanthine and correct for the oxygen effect in a fluid sample.03-22-2012
20120067742LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP - The present invention provides a linker for joining an electrode and a capture probe on a biochip, and a biochip comprising the linker. The impedance baseline of the linker of the present invention is three orders lower than the conventional long chain thiol linker when adopting in a fadaraic impedance biochip construction. With lower impedance baseline, the device designed to measure the signal of the biochip of the present invention could be further simplied on the electrical circuit design and be made in lower cost, compacter size and get the potential to be used in point-of-care applications. The present invention also provides a method of quantitatively detecting a concentration of a target analyte in a fluid sample by adopting the biochip and the linker of present invention.03-22-2012
20120103835SYSTEM AND/OR METHOD OF VALIDATING METERED BLOOD GLUCOSE FOR GLUCOSE SENSOR CALIBRATION - The subject matter disclosed herein relates to systems, methods and/or devices for calibrating sensor data to be used in estimating a blood glucose concentration. A relationship between sensor signal values and reference readings may be used to estimate a relationship between sensor signal values and measurements of blood glucose concentration.05-03-2012
20100147706SYSTEM AND METHOD FOR CODING INFORMATION ON A BIOSENSOR TEST STRIP - The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.06-17-2010
20100193377Electrochemical Detection of Silica Species - A systems and apparatus for measuring non-electroactive materials in liquids using electrochemical detection. A first electrical activity of a electroactive material is detected in absence of a target non-electroactive material (Step 08-05-2010
20100219085Analyte Sensor Offset Normalization - Measurements of current from a working electrode and current from a blank electrode are received and a ratio corresponding to the ratio of surface areas of the working electrode and the blank electrode is determined. This ratio is used to correct any differential current offset between an analyte (working) electrode and a control (blank) electrode to yield a more accurate net current output. Systems, methods and computer program products are further described for measuring an analyte concentration disclosed are for calculating the amount of an analyte in a fluid using a biosensor.09-02-2010
20090071848CERIUM OXIDE NANOPARTICLE REGENERATIVE FREE RADICAL SENSOR - An electrochemical sensor system for sensing free radicals or materials which generate free radicals in solution includes a working electrode coated with a plurality of cerium oxide nanoparticles and a counter electrode. A solution to be analyzed provides electrolytes to electrically couple the working electrode to the counter electrode. Electronics are connected to at least one of the working and counter electrodes for measuring and amplifying an electrical current signal generated by reduction or oxidation occurring at the working electrode, wherein in a presence of free radicals an electrical current signal flows between the working electrode and the counter electrode. The system can be used to sense the presence of hydrogen peroxide.03-19-2009
20110024308IMMUNOASSAY - Provided is an immunoassay for detecting a test substance with high sensitivity. The immunoassay is a method of detecting or measuring a test substance contained in a sample liquid, and includes: reacting, with the test substance, a first specifically binding substance which is immobilized on a support and is capable of binding specifically to the test substance and a second specifically binding substance which is labeled with a labeling substance and is capable of binding specifically to the test substance; separating, from the support, the second specifically binding substance which is unreactive with the test substance; eluting the labeling substance retained on the support; depositing the eluted labeling substance on a test element; and measuring electrochemically a catalyst reaction amount of the labeling substance deposited on the test element.02-03-2011
20110024307ANALYTE SENSOR - Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 02-03-2011
20110127172SYSTEMS AND METHODS FOR CARBOHYDRATE DETECTION - Carbohydrate detectors employing abiotic fuel cell designs are disclosed. The detectors produce current output using reactions between chemical dyes in alkaline solutions and carbohydrates, such as glucose. A linear relationship between current output of the detector and glucose concentration has been observed. This relationship may be used with measurements of current output when the glucose concentration is unknown to determine the unknown glucose concentration. In certain embodiments, the abiotic detectors may further employ electrodes, such as high surface area carbon materials and commercial air breathing electrodes, without the use of catalysts (i.e., precious metals or biocatalytic species) for glucose detection Organic dyes, such as methyl viologen (MV), methylene blue, methylene green, Meldola's blue, indigo carmine, safranin O, and the like, may serve as the electron mediators.06-02-2011
20100140113GAS SENSOR CONTROL APPARATUS AND METHOD - There is provided a control apparatus for a gas sensor, which has a sensor element equipped with first and second oxygen pumping cells. The sensor control apparatus is configured to drive the first oxygen pumping cell to adjust the oxygen concentration of gas under measurement, drive the second oxygen pumping cell to produce a flow of electric current according to the amount of oxygen pumped out of the oxygen concentration adjusted gas by the second oxygen pumping cell, perform specific drive control to control the amount of oxygen pumped by the second oxygen pumping cell to a predetermined level after startup of the sensor element and before the application of the drive voltage between the electrodes of the second oxygen pumping cell.06-10-2010
20110073496Error detection in analyte measurements based on measurement of system resistance - Measurement of the series track resistance of a working and counter electrode pair in an electrochemical test strip provide error detection for multiple variations in the quality of the test strip, as well as the operation of strip in the test meter. In particular, a single measurement of series resistance can be used to detect and generate an error message when an incorrect reading is likely to result due to (1) damaged electrode tracks, (2) fouled electrode surfaces, (3) dirty strip contacts, or (4) short circuit between the electrodes.03-31-2011
20110073495WATER ANALYSIS - A method of determining chemical oxygen demand (COD) of a water sample which is useful in a probe configuration includes the steps of a) applying a constant potential bias to a photoelectmchemical cell, having a photoactive working electrode optionally a reference electrode and a counter electrode, and containing a supporting electrolyte solution; b) illuminating the working electrode with a light source and recording the background photocurrent produced at the working electrode from the supporting electrolyte solution; c) adding a water sample, to be analysed, to the photoelectrochemical cell; d) illuminating the working electrode with a light source and recording the steady state photocurrent produced with the sample; e) determining the chemical oxygen demand of the water sample using the formula (I): where δ is the Nernst diffusion layer thickness, D is the diffusion coefficient, A is the electrode area, F the Faraday constant and iss the steady state photocurrent. The method can accommodate a broad range of light intensity and pH.03-31-2011
20100300897FLEXIBLE INDWELLING ELECTROCHEMICAL-BASED BIOSENSOR AND RELATED METHODS - A flexible indwelling electrochemical-based biosensor includes an elongated framework and an integrated electrochemical-based biosensor. The elongated framework is formed of an electrically conductive flexible material (e.g., a Nitinol) with a body portion, a sharp head, a distal end and a proximal end. The integrated electrochemical-based biosensor (such as an electrochemical-based glucose sensor) is integrated with the elongated framework in that the biosensor has a sensing element that is disposed over the body portion or sharp head of the elongated framework and a portion of the elongated framework is configured as an electrode component that electrically cooperates with the sensing element. The electrode component can, for example, be configured to electrically cooperate as a working electrode, counter electrode, reference electrode or combined reference/counter electrode of the sensing element. Moreover, the sharp head is disposed at the distal end of the elongated framework and the sharp head, the electrode component and at least the sensing element of the biosensor are configured for insertion into a target site (for example, a subcutaneous target site).12-02-2010
20120031777CONTROL AND CALIBRATION SOLUTIONS AND METHODS FOR THEIR USE - Control and calibration solutions are described that provide control and calibration data that is recognized by a test meter allowing the meter to segregate the control and calibration data from regular test data. Recognition and segregation of the control and calibration data can occur automatically with no additional input from the meter's user. Methods for use of the solutions are also provided.02-09-2012
20120031775PREPARATION OF MONOBASIC PHOSPHATE IONOPHORES - The present invention relates to the synthesis of lipophilic or immobilized monobasic phosphate (H02-09-2012
20120031774ELECTRODE FOR AN ELECTROCHEMICAL DEVICE AND METHOD FOR DETECTING HYDROGEN PEROXIDE USING THE ELECTRODE - An electrode for an electrochemical device includes a conductor, and an active layer formed on the conductor and including a polybenzimidazole polymer that contains at least one of the functional group of the following formula:02-09-2012
20110168576ELECTROCHEMICAL ASSAY - The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*)07-14-2011
20100078335Method and apparatus for assay of electrochemical properties - A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component.04-01-2010
20110132774STRIP HAVING TEMPERATURE COMPENSATING FUNCTION AND METHOD OF MEASURING BLOOD GLUCOSE USING THE SAME - Disclosed is a strip having a temperature compensating function, in which the temperature of the strip for blood collection for use in a blood glucose monitor is sensed and used as an error compensation value upon measuring blood glucose, thereby obtaining a very accurate blood glucose measurement regardless of ambient temperature and humidity and which includes first and second electrodes formed adjacent to each other to measure blood glucose, a connector inserted into a blood glucose monitor so as to be electrically connected thereto and one surface of which has upper terminals respectively connected to the first and second electrodes, a rectangular substrate including a chemically reactive member applied on or attached to the first and second electrodes, an upper cover covering an upper surface of the substrate and including a cut part to expose portions of the first and second electrodes, and a temperature sensor attached to the substrate to sense the temperature of the strip. A method of measuring blood glucose using the strip is also provided.06-09-2011
20100018877Small Volume In Vitro Sensor and Methods of Making - A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.01-28-2010
20120205259Method and Apparatus for Assay of Electrochemical Properties - The presence of a select analyte such as glucose in the sample is evaluated in an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes after the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current.08-16-2012
20120205260SYSTEM AND METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A SAMPLE FLUID - The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error.08-16-2012
20100018878METHOD OF REDUCING INTERFERENCES IN AN ELECTROCHEMICAL SENSOR USING TWO DIFFERENT APPLIED POTENTIALS - The present invention is directed to a method of reducing the effects of interfering compounds in the measurement of analytes and more particularly to a method of reducing the effects of interfering compounds in a system wherein the test strip utilizes two or more working electrodes. In one embodiment of the present invention, a first potential is applied to a first working electrode and a second potential, having the same polarity but a greater magnitude than the first potential, is applied to a second working electrode.01-28-2010
20090050492Nanoporous silicon-based electrochemical nucleic acid biosensor - A method and biosensor device for detecting single strand target nucleic acid by cyclic voltammetry is described. A porous silicon chip is linked to bound DNA probe complementary to the target nucleic acid. The device is particularly useful for detecting microorganisms and viruses that may be pathogenic or cancer genes, however any target nucleic acid can be detected by using a specific DNA probe.02-26-2009
20080197026TRANSITION METAL COMPLEXES WITH (PYRIDYL)IMIDAZOLE LIGANDS - Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme-based electrochemical sensors. The transition metal complexes include substituted or unsubstituted (pyridyl)imidazole ligands. Transition metal complexes attached to polymeric backbones are also described.08-21-2008
20120031776Transient Decay Amperometry - A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or less than the −0.5 decay constant of a Cottrell decay. The transient decay may result from a relatively short incubation period, relatively small sample reservoir volumes, relatively small distances between electrode surfaces and the lid of the sensor strip, and/or relatively short excitations in relation to the average initial thickness of the reagent layer. The biosensor system determines the analyte concentration from the output signal having a transient decay.02-09-2012
20120305410Porous Particle Reagent Compositions, Devices, and Methods for Biosensors - A reagent composition for a biosensor sensor strip is disclosed that provides for rapid rehydration after drying. The composition includes porous particles and is preferably formed as a colloidal suspension. The dried reagent composition including porous particles may provide analytically useful output from the sensor strip in a shorter time period than observed from dried reagent compositions using solid particles. The output signal from the porous particle compositions may be correlated to the analyte concentration of a sample within about two seconds. In this manner, an accurate concentration determination of an analyte concentration in a sample may be obtained in less time than from sensor strips including conventional compositions. The reagent composition including the porous particles also may allow for the redox reaction between the reagents and the analyte to reach a maximum kinetic performance in a shorter time period than observed from conventional sensor strips.12-06-2012
20110155589Systems, Devices, and Methods for Improving Accuracy of Biosensors Using Fill Time - Methods for determining a concentration of an analyte in a sample, and the devices and systems used in conjunction with the same, are provided herein. In one exemplary embodiment of a method for determining a concentration of an analyte in a sample, the method includes detecting a presence of a sample in an electrochemical sensor including two electrodes. A fill time of the sample is determined with the two electrodes and a correction factor is calculated in view of at least the fill time. The method also includes reacting an analyte that causes a physical transformation of the analyte between the two electrodes. A concentration of the analyte can then be determined in view of the correction factor with the same two electrodes. Systems and devices that take advantage of the fill time to make analyte concentration determinations are also provided.06-30-2011
20110155588METHOD FOR MEASURING ANALYTE CONCENTRATION IN A LIQUID SAMPLE - The blood glucose analysis technique and system described herein address the issue of hematocrit interference when rapidly detecting glucose concentrations. It addresses this issue by using a differential pulse voltammetry technique in which short high, frequency voltage pulses are applied to keep the diffusion layer within the reagent of the working electrode, and the pulses are applied in a limited voltage window (or range) that is below the peak, diffusion-limited current. The readings below the peak are then used to determine glucose concentrations. With this technique, glucose concentrations can be determined relatively fast (e.g., within 5 seconds) and independently of the hematocrit levels of the fluid being analyzed.06-30-2011
20090242428METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A LIQUID SAMPLE USING SMALL VOLUME SAMPLES AND FAST TEST TIMES - Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.5 μl and test times within ten seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.10-01-2009
20120181190Analyte Determination Methods and Devices - The present invention provides methods and apparatuses for analyte detection.07-19-2012
20120160709PROCESSES AND SYSTEMS FOR CHARACTERIZING AND BLENDING REFINERY FEEDSTOCKS - Refinery feedstocks can be characterized based on any of: dissociation of acids in the crude, breakup of naphthenic acid molecular associations, and/or dissociation of sulfur compounds in the feedstocks. The characterization is performed as a function of temperature via any of electrical resistivity measurement, vibrational spectroscopic analysis, voltammetry, electrochemical impedance spectroscopy (EIS) and combinations thereof The method can be practiced in any of refinery, terminal, and laboratories. It can be used in conjunction with models and hardware to optimize the usage of refinery feedstocks in the blending and valuation of the feedstocks. In one embodiment, the characterization of refinery feedstocks is via the use of EIS.06-28-2012
20120132544ELECTROCHEMICAL SENSOR - An electrochemical sensor for measuring an analyte in a fluid, the electrochemical sensor having a first working electrode that includes a redox species sensitive to the analyte to be measured and a second working electrode made from a conducting substrate absent the redox species. The electrochemical sensor being capable of operation so that electrochemical effects of active contaminants in the fluid can be removed/attenuated from electrochemical signals produced by the reduction/oxidation of the redox species in the presence of the analyte.05-31-2012
20100051481COULOMETRIC ANALYTE SENSING INSTRUMENT WITH AN ANALYTE-CONSUMING SENSOR IN A CLOSED CELL - A method for measuring the transmission rate of an analyte through a film. The method includes the steps of (i) separating a chamber into a first cell and a second cell with a known area of a film, (ii) flushing the first cell with an inert gas to remove any target analyte from the first cell, (iii) introducing a gas containing a known concentration of an analyte into the second cell, (iv) sealing the first cell to gas flow through the first cell, and (v) sensing any analyte in the first cell with a sensor that consumes the analyte at a rate greater than the rate at which the analyte is passing through the film, until a steady state rate of analyte consumption is measured by the sensor.03-04-2010
20100012528Small Volume In Vitro Analyte Sensor - A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable.01-21-2010
20120073987ELECTROCHEMICAL METHOD AND APPARATUS OF IDENTIFYING THE PRESENCE OF A TARGET - An electrochemical method of identifying the presence of a target protein in a sample is provided. The method comprises providing a redox probe modified to include a detector that is suitable to bind to the target protein, and exposing the sample to the detector-modified redox probe. A change in the electrochemical signal produced by the redox probe as compared to a control signal is indicative of the presence of the target protein.03-29-2012
20090020438ELECTROCHEMICAL CELL - The present invention relates to electrochemical cells including a first working electrode 01-22-2009
20120187000ELECTROCHEMICAL SENSORS - Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.07-26-2012
20110036729CONTROL LIQUID JUDGING METHOD AND ANALYSIS DEVICE - The present invention relates to a method for distinguishing between a sample and a control liquid in a system for analyzing a specific component in the sample by using an analyzing tool having a working electrode and an counter electrode. This discriminating method includes a first step of applying a voltage between the working electrode and the counter electrode, a second step of measuring a response current at certain intervals by use of the working electrode and the counter electrode, a third step of calculating a relative value for a peak value or an end value of the response current, a fourth step of calculating a change rate of the relative value, and a fifth step of distinguishing between the sample and the control liquid based on the change rate.02-17-2011
20120267259METHOD AND APPARATUS FOR DETECTING A LIPOPHILIC ANALYTE OF INTEREST IN A SAMPLE - Disclosed is a method and apparatus for detecting the concentration of a lipophilic analyte of interest in a complex sample matrix. The method comprises extracting the analyte of interest from said sample into an organic solvent comprising a dissolved electrolyte; providing a free radical species, preferably a free oxygen radical species, in said organic solvent; reacting the Canalyte of interest with said free radical species; and performing a measurement to detect the concentration of the free radical-reacted analyte reaction product.10-25-2012
20120298529OXIDATION/REDUCTION MEASUREMENT - Oxidation/reduction measurement is described. An aspect provides an oxidation/reduction quantification method, including: receiving intermittent oxidizer/reducer reference measurements from one or more reference sensors; receiving one or more substantially continuous oxidizer/reducer-related measurements from one or more corroboration sensors; and processing the one or more substantially continuous oxidizer/reducer-related measurements with the intermittent oxidizer/reducer reference measurements to generate substantially continuous representative oxidizer/reducer measurements. Other aspects are described.11-29-2012
20120080327METHOD FOR EVALUATING OXIDATION STRESS AND USE OF THE SAME - Provided is a simple, rapid blood cell analysis method (assay method using erythrocytes) utilizing a novel index. Using a measurement system having a working electrode and a counter electrode, an adhesion level of erythrocyte on the working electrode to which a positive potential, or a current that generates a positive potential, is applied is detected by an electrochemical measurement method. Oxidation stress is evaluated using the detection result.04-05-2012
20120080326SYSTEMS AND METHODS FOR IMPROVED STABILITY OF ELECTROCHEMICAL SENSORS - Methods for determining a concentration of an analyte in a sample, and the devices and systems used in conjunction with the same, are provided herein. In one exemplary embodiment of a method for determining a concentration of an analyte in a sample, a sample including an analyte is provided in a sample analyzing device having a working and a counter electrode. An electric potential is applied between the electrodes and a measurement of a parameter correlating to changes in a physical property of the sample analyzing device is calculated. A concentration of the analyte in view of the parameter correlating to a change in the physical property can then be determined Systems and devices that take advantage of the parameter correlating to changes in a physical property to make analyte concentration determinations are also provided.04-05-2012
20130175184Method and Apparatus for Encoding Test Strips - A test meter for receiving a test strip comprises: 07-11-2013
20120255875SYSTEMS AND METHODS FOR PROCESSING AND TRANSMITTING SENSOR DATA - Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated.10-11-2012
20110272294METHOD FOR MEASURING TEMPERATURE OF BIOLOGICAL SAMPLE, METHOD FOR MEASURING CONCENTRATION OF BIOLOGICAL SAMPLE, SENSOR CHIP AND BIOSENSOR SYSTEM - A sensor chip (11-10-2011
20130180868TEST METHOD FOR THE KETONE NUMBER OF AN ANIMAL SPECIMEN - A test method for the ketone number of an animal specimen is characterized in that a test parameter datasheet is set up by data modeling. Then a specimen from tested animal body is obtained. Next, the specimen is dripped onto the sensing end of an electrochemical test specimen, and an electrochemical tester is prepared. A test value correction procedure is built into or input to the electrochemical tester. With a parameter adjustment mode, the operational parameters of test value correction procedure unique to the electrochemical tester could be adjusted for adapting to the test mode of the species of tested animals. The sensing end of the electrochemical test specimen is inserted into the measurement slot of the electrochemical tester, so the ketone number of the specimen is displayed by the electrochemical tester.07-18-2013
20130118920SYSTEMS AND METHODS FOR IMPROVED ACCURACY FOR TEMPERATURE CORRECTION OF GLUCOSE RESULTS FOR CONTROL SOLUTION - Methods for determining a glucose concentration in a control solution with temperature correction that is more accurate than before with the devices and systems used in conjunction with the same, are provided herein.05-16-2013

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