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Biological material (e.g., microbe, enzyme, antigen, etc.) analyzed, tested, or included in apparatus

Subclass of:

204 - Chemistry: electrical and wave energy

204193000 - APPARATUS

204194000 - Electrolytic

204400000 - Analysis and testing

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
204403140 Enzyme included in apparatus 99
204403020 Disposable apparatus or apparatus having removable section (e.g., removable cartridge, etc.) 41
204403060 With semipermeable membrane 40
204403150 Electrode containing free carbon 7
Entries
DocumentTitleDate
20100051455BIOSENSOR TEST STRIP CARDS - An analyte test strip card comprises a plurality of biosensor test strips each having a reagent portion and a releasable and recloseable cover that overlaps the reagent portion. The strips are in a two dimensional array and are at least partially retained by a substantially credit card sized platform. Each strip is connected to adjacent strips by a first means for separation. At least some of the strips are connected to the retaining platform by a second means for separation.03-04-2010
20090194415PAIR OF MEASURING ELECTRODES, BIOSENSOR COMPRISING A PAIR OF MEASURING ELECTRODES OF THIS TYPE, AND PRODUCTION PROCESS - A pair of measuring electrodes comprising a first and a second, preferably in each case sheet-like electrode comprises an insulation layer arranged between said electrodes. One or more nanopores, which extend through said insulation layer as far as said first electrode, the surface of which is at least partially uncovered by said nanopores, are provided in each second electrode. The invention also describes a biosensor comprising a pair of measuring electrodes of this type, an electrochemical cell comprising a biosensor of this type and a process for producing said pair of measuring electrodes.08-06-2009
20110192720MICROFABRICATED LIQUID-JUNCTION REFERENCE ELECTRODE - Micromachined reference electrodes for use in miniaturized electrochemical sensors, and methods for fabricating such reference electrodes and electrochemical sensors, for example, as a part of a microfluidic system, are disclosed. Electrochemical measurements allow for inexpensive detection of a wide variety of (bio-)chemical compounds in solution. The reference electrode is one of the main parts of an electrochemical cell. The reference electrode, from which no current is drawn, has a stable, constant potential.08-11-2011
20120175252SENSING APPARATUS AND METHOD - A method of observing reaction intermediaries during a chemical reaction and comprising detecting an electrical signal output from an ion sensitive field effect transistor exposed to said reaction, and monitoring the detected electrical signal to discriminate discrete fluctuations in the electrical signal, the discrete fluctuations indicating reaction intermediaries occurring during a chemical reaction.07-12-2012
20090045054APPARATUS AND METHOD FOR ELECTROMAGNETICALLY DETECTING MICROORGANISM - An apparatus and a method for electromagnetically detecting microorganisms. The apparatus includes a pair of first electrodes which are positioned to be opposite to each other on a measuring cell and are connected to a power supply to generate an electric field around a solution contained in the measuring cell, a magnetic field generating unit which generates a magnetic field around the solution contained in the measuring cell in a perpendicular direction to the electric field, second electrodes which are positioned perpendicularly to both the electric field and the magnetic field, and a voltage measurer which measures the voltage generated between the second electrodes as the microorganisms move in the measuring cell. The apparatus determines the presence, quantity and identity of microorganisms with negative surface charge with improved sensitivity using the Hall effect.02-19-2009
20090095623Identification Method for Electrochemical Test Strips - The present invention provides a method and apparatus for creating test strips that may be identified based on differences in electrical conduction or resistance between contact point on the test strip. This is achieved by creating a base test strip with contact points that may be connected to other contact points by an electrical connection. These base test strips may be modified to create a difference in electrical conductivity between contact points, or a contact point may be eliminated. This modification can be used to distinguish different types of test strips based on electrical signature. Additionally, the base test strip may be created such that multiple modifications are possible to distinguish numerous characteristics of test strips.04-16-2009
20090095624Electroactive complex, electroactive probe and preparation method - Organic electrodes produced from electroactive polymers bonded to anti-ligands intended to interact specifically with ligands.04-16-2009
20100089750RF Tag on Test Strips, Test Strip Vials and Boxes - A glucose monitoring system, includes a glucose sensor strip or package of strips. The strip includes a substrate and a glucose monitoring circuit that has electrodes and a bodily fluid application portion of selected chemical composition. An antenna is integrated with the glucose sensor strip. A RFID sensor chip is coupled with the glucose sensor strip and the antenna. The chip has a memory containing digitally-encoded data representing calibration and/or expiration date information for the strip.04-15-2010
20090057148In Vivo Analyte Monitor With Malfunction Detection - The measuring system for in vivo monitoring of an analyte concentration with malfunction detection, comprises an electrode system, a potentiostat and an evaluation unit. The electrode system has a working electrode, a reference electrode, and a counter electrode. The potentiostat is for adjusting a difference of potential between the electric potential of the working electrode and the electric potential of the reference electrode to a specified value and for measuring an electric current flowing between the working electrode and the counter electrode. The potentiostat comprises a working electrode terminal for connection to the working electrode, a reference electrode terminal for connection to the reference electrode, and a counter electrode terminal for connection to the counter electrode. The evaluation unit monitors the electric potential of the counter electrode and generates a malfunction signal when said potential is outside a specified reference range. A method of operation is also disclosed.03-05-2009
20090057147Devices and methods for biochip multiplexing - The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples.03-05-2009
20080202927Devices and methods for biochip multiplexing - The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples.08-28-2008
20090014327Analyte Test Sensor and Method of Manufacturing the Same - An analyte test sensor for use in measuring the concentration of a particular analyte in a test sample includes a non-conductive substrate, a reference electrode deposited on the substrate, a working electrode deposited on the substrate and a compensation electrode deposited on the substrate. The compensation electrode is provided with a resistive ladder and is designed to correct for test result inaccuracies which are the result of variances in the manufacturing of the test sensor. Specifically, in one embodiment, the compensation electrode corrects for test result inaccuracies in an analog manner by shunting a portion of the working current away from working electrode. In another embodiment, the compensation electrode corrects for test result inaccuracies in a digital manner by providing a calibration code which is proportional its resistance value. A batch of analyte test sensors are preferably manufactured in the following manner. An initial batch of the test sensors is constructed. Then, a limited sampling of the sensors is tested for accuracy using a control sample. Based on the test results, the resistance value of the compensation electrode for each remaining sensor in the batch is adjusted accordingly.01-15-2009
20130161189ORNAMENT FOR PLANT - The ornament for fresh flower has, for example, the first decorative part encloses and maintains on the stem side of fresh flower, the second decorative part of the image of a doll's head and the third decorative part of the image of the doll's body. The first decorative part, the second decorative part and the third decorative part are packed and sold in bags separately (Individually).06-27-2013
20120234677BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode 09-20-2012
20080296154Analysis Device - An analysis device is provided for analysing a substance sample. The device comprises a plurality of sample activatable battery cells connected in series.12-04-2008
20110278167Biosensor, thin film electrode forming method, quantification apparatus, and quantification method - A biosensor according to the present invention comprises a support 11-17-2011
20080302659ELECTROCHEMICAL BIOSENSORS AND ARRAYS - Electrochemical sensor devices are provided, in various amperometric, potentiometric, and conductometric sensor device configurations. An amperometric sensor device may include a structural body which has at least one reservoir that has at least one opening; a working electrode located within the reservoir; analyte sensor chemistry located within the reservoir and deposited on at least the working electrode; an auxiliary electrode located outside of the reservoir; a reference electrode; at least one reservoir cap closing the opening to isolate the working electrode and analyte sensor chemistry within the reservoir and to prevent an analyte outside of the reservoir from contacting the analyte sensor chemistry; and means for rupturing or displacing the reservoir cap to permit the analyte from outside of the reservoir to contact the analyte sensor chemistry.12-11-2008
20090152110Chip For Cell Electrophysiological Sensor, Cell Electrophysiological Sensor Using The Same, and Manufacturing Method of Chip for Cell Electrophysiological Sensor - A chip for a cell electrophysiological sensor has a substrate. The substrate has a through-hole formed from the upside to the downside, and the opening of the through-hole is formed in a curved surface curved from the upside and downside of the substrate toward the inner side of the through-hole. In this configuration, the electrolyte solution (first electrolyte solution and second electrolyte solution) flows more smoothly, and the sample cell can be sucked accurately, and the trapping rate of the sample cells is improved.06-18-2009
20090145753Biomechanical test system, measurement device, and biochemical test strip - A biochemical test system, a measurement device, and a biochemical test strip are provided. The biochemical test strip includes an insulating substrate, an electrode system disposed on the insulating substrate, and an identifying unit disposed on one side of the insulating substrate. The identifying unit includes N components, and at least one of the N components includes a groove. It should be noted that the term “N” in this specification is an integer greater than two. The measurement device includes a microprocessor and a connector, wherein the connector is coupled to the identifying unit for receiving a signal of an identification code corresponding to the identifying unit, and the microprocessor is coupled to the connector for receiving the signal from the connector.06-11-2009
20090095622Biosensor and method to produce biosensor - A biosensor is a sensor strip that is folded to form a base and a cover. The base has a reactive layer, two electrodes, a compensating electrode and a variable resistive pad. The reactive layer is formed on the base. The electrodes are formed on the base and connect to the reactive layer to an end of the base. The compensating electrode is formed between the electrodes and is connected to one electrode by the variable resistive pad having an adjustable resistivity to account for manufacturing errors. The cover is shorter than and adhered to the base and has a sample-dropping section corresponding to the reactive layer to allow a liquid sample to be added to the reactive layer. Operators insert the biosensor into the biosensor detector and obtain a correct result without calibrating the biosensor detector so preventing human calibration errors.04-16-2009
20100264024BIOCHIP, BIOSENSOR AND INSPECTION SYSTEM - A biochip, includes: an ink-jet head portion detachably mountable to a biosensor; a sensing electrode formed with a work electrode, a reference electrode, and a counter electrode; and a thin film transistor.10-21-2010
20100084267PAIR OF MEASURING ELECTRODES, BIOSENSOR COMPRISING A PAIR OF MEASURING ELECTRODES OF THIS TYPE, AND PRODUCTION PROCESS - A pair of measuring electrodes comprising a first and a second, preferably in each case sheet-like electrode comprises an insulation layer arranged between said electrodes. One or more nanopores, which extend through said insulation layer as far as said first electrode, the surface of which is at least partially uncovered by said nanopores, are provided in each second electrode. The invention also describes a biosensor comprising a pair of measuring electrodes of this type, an electrochemical cell comprising a biosensor of this type and a process for producing said pair of measuring electrodes.04-08-2010
20090090623Biosensor having integrated heating element and electrode with metallic catalyst - The invention discloses a biosensor includes a strip having an integrated heating element and an electrode with metallized graphite including metal in the range of 0.1-5% in weight; graphite in the range of below 55% in weight; and polymer. The biosensor further includes an electric measuring device having a slot enabling the strip to insert therein.04-09-2009
20090057146ANALYTE TEST STRIP WITH IMPROVED REAGENT DEPOSITION - An analyte, system, strip and method are described. In one example, an analyte test strip is provided that includes a substrate, electrically conductive material and an isolated portion of the electrically conductive material. The substrate has a generally planar surface that extends from a first end to a second end. The electrically conductive material is disposed on the generally planar surface to define a plurality of electrodes spaced apart from each other. The isolated portion of the electrically conductive material is disposed between at least two electrodes so that the isolated portion is not in electrical communication with the plurality of electrodes.03-05-2009
20130098762Patch-Clamp Providing On-Chip Thermal Gradient - A patch clamp system providing precise and rapid temperature control of constrained cell membranes employs the thermal element attached to the substrate of the patch clamp. In one embodiment, the thermal element is a Peltier device fabricated on a silicon membrane wafer bonded to the substrate of the patch clamp.04-25-2013
20110203923SENSING APPARATUS AND PROCESS - A sensing apparatus with a connector, a sensor lead and a sensor module with a spacer placed over electrodes that have been deposited on a substrate. The spacer may have a space for receiving an enzyme. End portions of the sensor module may be encapsulated, such as with molded beads. A sensor lead may attach to the sensor module and may have an outer tubing that passes over the module and attaches to the beads at the end of the sensor module. The sensor lead may also attach to the connector such that the sensing apparatus may be electrically coupled to a pump, electronics or other devices. The sensing apparatus may be implanted into a vein or artery.08-25-2011
20110203924Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.08-25-2011
20110198222ELECTROLYTE SENSOR USING CONDUCTIVE ELASTOMER - An electrolyte sensor that uses conductive elastomer electrodes. Examples of the intended analytes for sensor use include those found in urine, saliva, blood, feces and spinal fluid, although other analytes exist for electrolyte detection. Conductive elastomer trace electrodes are separated by a gap or channel which can be bridged by an electrolyte and thereby complete an electrical circuit to an alarm or other circuitry. Gap or channel distances vary the level of electrical resistance associated with detecting certain analytes.08-18-2011
20080283396Analyte Sensor with Insertion Monitor, and Methods - A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.11-20-2008
20080308418Adhesion of Membranes on Nitride Layer in Electrochemical Sensors by Attachment to Underlying Oxide Layer - An electrochemical sensor is provided that exhibits improved adhesion of the membrane to the nitride layer used as an insulating layer in silicon- or silicon-oxide-based electrochemical sensing devices. The sensing devices include a substrate, an oxide disposed on the substrate, a nitride disposed on the oxide, an electrically conductive structure disposed on the oxide layer, and an electrode disposed on the oxide layer and electrically coupled to the electrically conductive structure. At least one opening is formed in the nitride layer to form at least one adhesion trench that exposes a surface region of an oxide layer underlying the nitride layer. The membrane covers the electrode, and contacts the oxide surface regions exposed by the adhesion trenches. The contact between the membrane and the oxide surface region provides for improved adhesion of the membrane to the electrochemical sensing device.12-18-2008
20080210557SUBCUTANEOUS GLUCOSE ELECTRODE - A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably three or four-layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). An outer (fourth) layer is biocompatible.09-04-2008
20100270149Smart Sensor Ports and Methods of Using Same - The present disclosure provides an orientation-nonspecific sensor port for use in analyte meters designed to detect and quantify analyte levels in a fluid sample along with methods of using the same. The present disclosure also provides compositions and methods for facilitating the correct insertion of a sensor into a corresponding analyte meter.10-28-2010
20100140087BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode 06-10-2010
20080257726EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.10-23-2008
20080257725Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate.10-23-2008
20090178923ELECTROCHEMICAL SENSOR FOR THE DETERMINATION OF AN ANALYTE CONCENTRATION - The invention relates to an electrochemical sensor for the determination of a concentration of at least one analyte in a medium, in particular a body tissue and/or a body fluid, to an apparatus that includes the electrochemical sensor, and to a use of the electrochemical sensor, and finally to a method for producing it. The electrochemical sensor has an isolation element and at least two electrodes. The at least two electrodes comprise at least one working electrode and at least one further electrode, in particular at least one counter electrode and/or at least one reference electrode. The at least two electrodes run parallel to one another and form an electrochemical measuring cell of the electrochemical sensor.07-16-2009
20120067722BIOSENSOR FOR MEASURING BIOMATERIAL - The present invention relates to an apparatus for measuring a biomaterial, comprising: a first substrate having a recess in one side thereof; a second substrate having reference and operating electrodes where a biochemical reaction of a biomaterial occurs, and first and second delivery electrodes delivering electric signals from the reaction to a detector; and reaction reagents fixed at the second substrate causing the reaction with the biomaterial, wherein the first or the second substrate has a tilted surface toward a sample-inlet in a height direction. The second substrate is attached to the first substrate such that a portion of the recess forms the sample-inlet, and the reference and operating electrodes are directed toward the recess. The tilted surface prevents the sample-inlet from being blocked by a finger of the user when introducing the biomaterial through the sample-inlet in the event the used substrate has three-dimensional structures with substantial thickness.03-22-2012
20080277275TREATMENT APPARATUS, SOLUTION STIRRING METHOD AND SOLUTION TRANSFER METHOD - The electrolytic reaction of a solution supplemented with oxidation-reduction substances is caused in a magnetic field. Lorentz force generated by the interaction between an electrolytic current and the magnetic field is utilized. As a result, the effective stirring or transfer of a solution as well as the detection of a biologically relevant substance with high precision can be achieved without causing the aggregation or uneven distribution of magnetic beads or the like.11-13-2008
20120193228TEST STRIP - A test strip is revealed. The test strip includes a detection area, at least one outer sampling area, and a circuit system. The detection area includes a sampling hole, at least one sampling channel corresponding to the sampling hole, and at least one reaction area in the sampling channel. An inner sampling area is disposed around the sampling hole and an inner sampling opening is on an edge of the inner sampling area for communicating with the sampling channel and the sampling hole. The outer sampling area is located on an outer side of the test strip. The outer sampling area includes an outer sampling opening in communication with the sampling channel. The circuit system is electrically connected to the reaction area. The test strip further includes at least one pressing part located around the sampling hole for pressing against a test area and preventing cross-infection.08-02-2012
20090260985ANALYTE SENSOR WITH INSERTION MONITOR, AND METHODS - A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.10-22-2009
20120103806LIQUID SAMPLE MEASUREMENT METHOD AND APPARATUS - A liquid sample measurement apparatus of the present invention is provided with a timer (05-03-2012
20100258438BIOSENSOR - In a biosensor that detects introduction of a sample liquid into a specimen supply path using a detecting electrode, a means of improving accuracy of detection is provided. The biosensor has: an electrode system including measuring electrode, counter electrode, and detecting electrode on first electrically insulating support; specimen supply path for introducing the sample liquid; and reagent layer used for quantifying a substrate contained in the sample liquid. The means is characterized in that detecting electrode is spaced from measuring electrode by a distance sufficient for the sample liquid to sufficiently cover measuring electrode before the sample liquid reaches detecting electrode.10-14-2010
20100213056Interaction Detecting Portion with Electrode Having the Same Potential, Sensor Chip Using the Same, and Interaction Detector - There are provided an interaction detecting portion including an interaction region in the whole of which an electrodynamic effect is obtained, and which has a simpler structure, and the like. There is provided an interaction detecting portion 08-26-2010
20100224487Biosensor having identification information and apparatus for reading identification information of biosensor - A biosensor is provided, including an identification information recording unit having identification information of the biosensor recorded thereon, where the identification information recording unit is a color tag that is attached on the biosensor and indicates the identification information by color, chroma of color, or arrangement pattern of colors. An apparatus for reading identification information of a biosensor is provided, including: a biosensor sensing unit detecting the biosensor; a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon; a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section; and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor.09-09-2010
20100219071BIOSENSOR - The present invention relates to a biosensor. The biosensor includes a support substrate, an electrically conductive coating positioned on the support substrate, the coating being formed to define electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and a cover cooperating with the support substrate to define a channel. At least a portion of the electrodes are positioned in the channel.09-02-2010
20100243441BIOSENSOR WITH PREDETERMINED DOSE RESPONSE CURVE AND METHOD OF MANUFACTURING - The present invention provides a system of biosensors whose dose-response curves are maintained within a predetermined and desired range or tolerance during production by selecting a feature of the biosensors that can be varied during production. For example, in one exemplary embodiment the effective area of the working electrode of an electrochemical biosensor can be varied during production as needed to offset variations that occur, e.g., in the reagent of the biosensors as production proceeds. In another exemplary embodiment, the dose-response curve of biosensors not yet produced can be predicted and one or more features of these biosensors can be selected to maintain the dose-response curve within a predetermined range or tolerance.09-30-2010
20100187106ULTRA-SENSITIVE, PORTABLE CAPILLARY SENSOR - A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface. The analysis time provided by the biosensor system of the invention is shorter than has heretofore been possible.07-29-2010
20100122904INCORPORATING CMOS INTEGRATED CIRCUITS IN THE DESIGN OF AFFINITY-BASED BIOSENSOR SYSTEMS - A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a complementary metal-oxide-semiconductor (“CMOS”) integrated circuit. The biosensor system further includes an optical filter fabricated on the CMOS integrated circuit. Additionally, a plurality of capturing probes is optically coupled to the CMOS integrated circuit. Alternatively, another type of biosensor system includes a silicon substrate. The alternative biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the alternative biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the alternative biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the alternative biosensor system includes a plurality of probes attached to the sensing electrode.05-20-2010
20100126856Analyte Test Instrument Having Improved Versatility - An analyte test instrument that has a test strip circuitry that can be configured using information provided by a calibration strip to perform assays with test strips having two electrodes and test strips having three electrodes. The analyte test instrument of this invention comprises: 05-27-2010
20100000861PACKAGING SYSTEM FOR TESTING DEVICES - A packaging system is disclosed. The packaging system comprises an analyte-testing device including a fluid-receiving portion. The packaging system further comprises a film adapted to cover the fluid-receiving portion of the analyte-testing device. The film has a first side and an opposing second side. The first side is adapted to contact the analyte-testing device. The packaging system further comprises adhesive positioned on at least a portion of the first side of the film. The packaging system further comprises a desiccant material positioned on the first side of the film such that the desiccant material is adapted to be in vapor communication with the fluid-receiving portion of the analyte-testing device.01-07-2010
20110000785ELECTRICAL PATTERNS FOR BIOSENSOR AND METHOD OF MAKING - The present invention provides an inventive biosensor that includes multiple regions in which the electrical pattern is formed from different electrically conductive materials. The present invention also provides an inventive method for mass producing biosensors as just described. In one embodiment of this method, first and second different electrically conductive materials are deposited side by side on a portion of an electrically insulating base material, and a plurality of electrical patterns is formed on the portion of the base material. Each electrical pattern includes a first region formed from the first electrically conductive material electrically connected to a second region formed from the second electrically conductive material. The electrically conductive materials can be deposited as layers on the base material and portions of the layers can be removed to form the electrical patterns, or, the electrical patterns can be formed by transferring the conductive material in the shape of the electrical pattern directly to the base material, such as by a laser direct transfer technique.01-06-2011
20110017593HIGHLY SENSITIVE BIOSENSOR, BIOCHIP COMPRISING THE SAME AND METHOD FOR MANUFACTURING THE SAME - The present invention has a feature to form a biocompatible dielectric thin film on the surface of a metal electrode in a biosensor constructing a biochip. When using such a biocompatible dielectric thin film, this non-specific adsorption between a protein such as enzyme and a metal electrode can be prevented. Therefore, the present invention can escape a phenomenon that inhibits the reaction of a biomolecule due to the non-specific adsorption on the surface of a metal electrode. In addition, when the dielectric thin film having a high dielectric constant, as a biocompatible dielectric thin film, is made on the surface of a metal electrode, the sensitivity of an electrical detection according to the reaction of a biomolecule can be improved.01-27-2011
20110017592BIOSENSOR - An electrode assembly that may be used, for example, for electrochemically analysing a sample to determine the presence (or otherwise) of a species having biomembrane activity comprises at least one working electrode comprised of a conductive carrier substrate having a surface coated with mercury immobilised on the surface of the substrate. The surface of the mercury remote from said substrate is coated with a phospholipid layer. The preferred carrier substrate is platinum. The electrode assembly may be incorporated in a flow cell.01-27-2011
20100133100SENSOR AND APPARATUS FOR ANALYSING GASES PRESENT IN BLOOD - A galvanic sensor for analyzing gases present in blood includes a duct suitable for being crossed by a flow of gas and provided with an inlet opening and an outlet opening, a reference galvanic element including a container containing an electrolytic solution in which a reference electrode is inserted, and a measuring galvanic element. The container is fixed to the duct and the measuring galvanic element includes a measuring electrode arranged transversally to the axis of the duct and a filiform element having a high capillarity so as to act as a wick. The filiform element is anchored to the container and has a first end contacting the measuring electrode and a second end contacting the electrolytic solution. The measuring element of the galvanic sensor is extremely miniaturized and allows to detect in real time and continuously gases in traces, on the order of parts per million or even lower.06-03-2010
20100133099ELECTRONIC DEVICE ASSEMBLY WITH SAFETY ELECTRIC CONNECTOR - The application provides an assembly comprising a housing (06-03-2010
20100133098Methods and Devices for Concentration and Purification of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desportion/Ionization (MALDI) Mass Spectrometry (MS) - Analytical methods and devices are disclosed for separating low abundance analytes by electrophoretically driving the analytes through a sieving matrix to first remove high molecular weight species. Subsequently the remaining low abundance analytes are electrophoretically focused onto a capture membrane where the analytes become bound within a small capture site. After this step the capture membrane may be allowed to dry and then attached to a conductive MALDI sample plate.06-03-2010
20080257727EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.10-23-2008
20110073476Stackable Electrochemical Analyte Sensors, Systems and Methods Including Same - In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base with first and second ends, a concave recess in the first end, a second end receiving surface, and a sidewall extending between the ends. An electrode may be provided on the receiving surface with an electrochemically-active region coupled to the electrode. A conductor in electrical contact with the electrode may extend along the sidewall and may be adapted to be in electrical contact with a first contact of an analyte meter. Manufacturing methods and systems utilizing and dispensing the analyte sensors are provided, as are numerous other aspects.03-31-2011
20110073474SURFACE ACOUSTIC WAVE DEVICE AND SURFACE ACOUSTIC WAVE BIOSENSOR - A surface acoustic wave device, including: a piezoelectric substrate; an interdigitated transducer electrode disposed on the substrate; an oxide film disposed on surface of the interdigitated transducer electrode; and a hydrophobic film disposed on a surface of the oxide film.03-31-2011
20110048938METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS - A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.03-03-2011
20110042210METHOD FOR PREPARING METAL NANOPARTICLES USING METAL SEED AND METAL NANOPARTICLES COMPRISING METAL SEED - The invention relates to a method of manufacturing metal nanoparticles by using metal seed and metal nanoparticles including such metal seed. It is to provide the Au nanoparticles prepared by a method comprising: preparing a solution by adding a monosurfactant into a non-aqueous solvent; heating the solution; preparing a platinum seed solution by adding platinum salt chosen form platinum, palladium, iridium into the heated solution; and adding gold salt in the platinum seed solution.02-24-2011
20090127112Biologically active metal-coated proteins - Metal-coated proteins, being dissolvable or suspendable in aqueous media and/or retaining a biological activity of the protein, a process and intermediates for preparing same are disclosed. Further disclosed are a pharmaceutical composition containing and a method of treating bacterial and fungal infections utilizing biologically active metal-coated proteins. Conductive elements, electronic circuits containing same, electrodes and biosensor systems utilizing same, and imaging probes, all containing the metal-coated proteins, are also disclosed.05-21-2009
20090127113Microfluidic detector and manufacturing method - A micro-fluidic detector applied for detecting analytes in a fluid sample is disclosed. The micro-fluidic detector comprises a mixing area, a flow area and at least one detection module. The mixing area has a conductive top plate and a plurality of first electrodes for mixing a first fluid and a second fluid so as to form the fluid sample. The flow area has two second electrodes, positioned side by side, for driving the fluid sample to flow. The detection module is used for detecting analytes in the fluid sample flowing in the flow area. The mixing area uniformly mixes the first fluid and the second fluid via an electric field generated by applying a voltage potential, with respect to the conductive top plate, to one by one of the first electrodes in the mixing area. The flow area drives the fluid sample via an electric field generated by the second electrodes.05-21-2009
20080314746Analyzer - It is an object of this invention to measure small amounts of a plurality of sample solutions at the same time. The small amounts of sample solutions are respectively placed on measuring electrodes, a medium is placed across the plurality of sample solutions, a liquid joint of a reference electrode is brought into contact with the medium, and a potential difference between each of the measuring electrodes and the reference electrode via the medium is measured.12-25-2008
20080314745Biosensor and its production - Biosensor for analyzing biological fluids having: 12-25-2008
20080237039EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.10-02-2008
20120241318SYSTEM AND METHODS FOR DETERMINING AN ANALYTE CONCENTRATION INCORPORATING A HEMATOCRIT CORRECTION - Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The blood sample is introduced into a test strip with portions of the blood sample being directed to both a first capillary and a second capillary. The first capillary configured to electrochemically determine a concentration of a first analyte in a blood sample by measuring a signal across a set of electrodes. The second capillary is configured to determine a hematocrit value of the blood sample by measuring a signal across a second set of electrodes.09-27-2012
20100320086FLEXIBLE BIOSENSOR AND MANUFACTURING METHOD FOR THE SAME - Provided are a flexible biosensor using a gold binding substance and a method for manufacturing the same.12-23-2010
20100116655CHEMICAL MESSENGER SENSOR - A sensor for the detection of chemical messengers is described herein. In particular a sensor for the detection of catecholamines, for example dopamine, epinephrine or norepinephrine, is reported. Catecholamines play pivotal roles as neurotransmitters and hormones in the human body. An electrode for detecting a catecholamine comprising a conducting or semi-conducting substrate, and a polymer comprising polyethylenedioxythiophene on said substrate is disclosed. The polymer is doped with a cyclodextrin macrocycle. Suitable cyclodextrin macrocycles include anionic cyclodextrin macrocycles, for example sulfonated β-cyclodextrins (CDs). Also, disclosed in sensor capable of selectively detecting a catecholamine in the presence of ascorbic acid (ascorbate).05-13-2010
20110174613Biosensor, thin film electrode forming method, quantification apparatus, and quantification method - A biosensor is disclosed comprising a support; a conductive layer composed of an electrical conductive material such as a noble metal, for example gold or palladium, and carbon; slits parallel to and perpendicular to the side of the support; working, counter, and detecting electrodes; a spacer which covers the working, counter, and detecting electrodes on the support; a rectangular cutout in the spacer forming a specimen supply path; an inlet to the specimen supply path; a reagent layer formed by applying a reagent containing an enzyme to the working, counter, and detecting electrodes, which are exposed through the cutout in the spacer; and a cover over the spacer. The biosensor can be formed by a simple method, and provides a uniform reagent layer on the electrodes regardless of the reagent composition.07-21-2011
20090308741Sensor arrangement comprising an electrode for detecting diffused loaded particles - A sensor arrangement for detecting particles potentially contained in an analyte is disclosed. The arrangement includes a substrate; at least one sensor electrode which is arranged on and/or in the substrate and on which scavenger molecules, which hybridize with particles that are potentially contained in an analyte and are to be detected, are immobilized, electrically charged particles generated by hybridization being detectable on the at least one sensor electrode; and at least one diffusion detection electrode which is arranged in a surrounding region of the at least one sensor electrode and is embodied in such a way that it detects electrically charged particles that are generated by hybridization and can be diffused away by the at least one sensor electrode.12-17-2009
20110186428ELECTRODE ARRANGEMENTS FOR BIOSENSORS - The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode.08-04-2011
20110132759Biosensors and Methods of Making - Devices and methods for determining the concentration of an analyte in a sample of liquid are provided.06-09-2011
20090188791Biosensor and its production - Biosensor by means of which biological fluids are analysed, comprising at least the 07-30-2009
20100147683NOVEL POTENTIOMETRIC CHOLESTEROL SENSOR FOR THE QUANTITATIVE ESTIMATION OF TOTAL CHOLESTEROL IN HUMAN BLOOD SERUM - The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Selective Field Effect Transister) coated with molecular imprint of cholesterol on the SiO06-17-2010
20080223719Potentiostat circuit - A potentiostat is provided for a biosensor circuit and permits sequential and simultaneous measurements to be performed at different cells across a matrix of biosensing devices. Accordingly, a potentiostat comprises a first differential amplifier for receiving a scanning voltage at a first input terminal and a voltage at the reference electrode at a second input terminal and for generating an output voltage at an output terminal to be applied to the working electrode, wherein, when in use, a feedback loop of the potentiostat circuit is closed between the reference electrode and the working electrode.09-18-2008
20120145541DISEASE DIAGNOSING BIOSENSOR CAPABLE OF PROMPTLY SEPARATING BLOOD CELLS - The present invention relates to a disease diagnosing biosensor capable of promptly separating blood cells, in which a disease can be analyzed further accurately by adding a blood cell separating pad on a front or rear side of a capillary tube and separating the blood cells and plasma within 1 or 2 seconds owing to distribution of hydrophilic and hydrophobic segments. The entire configuration of the biosensor according to the present invention includes a base film; electrodes arranged on a top surface of the base film; a space film covering a top surface of the electrodes; a blood cell separating pad connected to a rear side of the space film; a capillary tube added on a rear top surface of the space film; and a cover film covered on a top surface of the capillary tube and the blood cell separating pad.06-14-2012
20120037506METHOD OF MEASURING HEMATOCRIT (Hct), SENSOR USED IN THE METHOD, AND MEASURING DEVICE - The present invention provides a method of electrochemically measuring a hematocrit (Hct) value using a sensor, capable of achieving excellent measurement accuracy and reliability and also provides a sensor used in the method. The method of electrochemically measuring a hematocrit (Hct) value of blood include: providing an electrode system having a working electrode (02-16-2012
20120305394BIOSENSOR HAVING IDENTIFICATION INFORMATION AND APPARATUS FOR READING IDENTIFICATION INFORMATION OF BIOSENSOR - An apparatus for reading identification information of a biosensor is provided, including a biosensor sensing unit detecting the biosensor, a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon, a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section, and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor.12-06-2012
20110315548BIOLOGICAL SIGNAL DETECTION ELECTRODE AND BIOLOGICAL SIGNAL DETECTION APPARATUS - A biological signal detection electrode includes an electrode element and a plurality of drought-resistant electrolytic solution soaking parts. The electrode element is made of a conductive material and has a surface. The plurality of drought-resistant electrolytic solution soaking parts are placed at predetermined intervals on the surface of the electrode element, are formed to have a thickness that allows contact with a scalp without hair being sandwiched between the electrode element and the scalp, and are soaked in a drought-resistant electrolytic solution including a drought-resistant liquid and a conductive liquid.12-29-2011
20120043201METHOD AND APPARATUS FOR MEASURING SAMPLE REACTION RESULTS ON BIOSENSOR - Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.02-23-2012
20090057149Method of Manufacturing a Diagnostic Test Strip - A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer.03-05-2009
20110073475Analyte Sensor - An analyte sensor configured to be implanted in the body of the user unassisted by an introducer sharp.03-31-2011
20120312684Multiple-Biosensor Article - An article suitable for conducting one or more assays with an apparatus, e.g., a meter, for determining the presence or concentration of an analyte in a sample of biological fluid. The article contains a plurality of biosensors arranged in such a manner that each of the biosensors can be utilized before the article must be removed from the apparatus.12-13-2012
20100288632Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.11-18-2010
20120211361Rapid-Read Gated Amperometry Devices - A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Input signals including multiple duty cycles of sequential excitation pulses and relaxations are input to the sample. One or more signals output from the sample within 300 ms of the input of an excitation pulse may be correlated with the analyte concentration of the sample to improve the accuracy and/or precision of the analysis. Determining the analyte concentration of the sample from these rapidly measured output values may reduce analysis errors arising from the hematocrit effect, mediator background, and other error sources.08-23-2012
20120168306INCORPORATING CMOS INTEGRATED CIRCUITS IN THE DESIGN OF AFFINITY-BASED BIOSENSOR SYSTEMS - A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a silicon substrate. The biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the biosensor system includes a plurality of probes attached to the sensing electrode.07-05-2012
20100051456ANALYSIS IMPLEMENT WITH OPENING IN INSULATION FILM - The present invention relates to an analytical tool (X) which includes a substrate (03-04-2010
20100270150Smart Sensor Ports and Methods of Using Same - The present disclosure provides an orientation-nonspecific sensor port for use in analyte meters designed to detect and quantify analyte levels in a fluid sample along with methods of using the same. The present disclosure also provides compositions and methods for facilitating the correct insertion of a sensor into a corresponding analyte meter.10-28-2010
20120247956BIOSENSOR STRIP AND MANUFACTURING METHOD THEREOF - The present invention is related to a biosensor strip and a manufacturing method thereof. The biosensor strip comprises an electrode layer that has a first electrode pattern and a second electrode pattern. The two electrode patterns are provided on a base by different manufacturing methods. The first electrode pattern is made by a first electrically conductive material that may consist of precious metal and the second electrode pattern is made by a second electrically conductive material that may not consist of precious metal.10-04-2012
20120073968SENSOR USED TOGETHER WITH A DETECTOR TO MEASURE BIOMATERIAL, AND APPARATUS USING SAME - The present invention relates to a sensor used together with a detector to measure biomaterial, and to an apparatus using same. A sensor of the present invention comprises: a body portion with a three-dimensional shape, having a biomaterial introduction hole, and attachable and detachable to/from a detector; a sensor portion with a plurality of reaction electrodes formed on one surface thereof, and a plurality of transfer electrodes formed on the other surface thereof; and an analyzer reagent fixed above the reaction electrodes. The sensor portion, together with the body portion, forms a reaction chamber connected to the biomaterial introduction hole, and is attached to the body portion such that the reaction electrodes are oriented toward the reaction chamber. According to the present invention, attachment and detachment is easy, even for the elderly, and the contamination of the sensor can be minimized.03-29-2012
20110120864CELLULAR ELECTROPHYSIOLOGY SENSOR CHIP AND CELLULAR ELECTROPHYSIOLOGY SENSOR USING THE CHIP, AND METHOD OF MANUFACTURING CELLULAR ELECTROPHYSIOLOGY SENSOR CHIP - A cellular electrophysiology sensor is adapted to measure an electrical change of a test cell. A chip for the sensor includes a diaphragm, and a thermally-oxidized film mainly containing silicon dioxide on the diaphragm. The diaphragm includes a silicon layer and a silicon dioxide layer on an upper surface of the silicon layer. A through-hole passing through the silicon layer and the silicon dioxide layer is formed. The through-hole has an opening which opens at the silicon dioxide layer and is adapted to capture the test cell. The thermally-oxidized film is provided on an inner wall surface of the through-hole, and unified with the silicon dioxide layer at the opening of the through-hole. This cellular electrophysiology sensor chip can stably capture the test cell and provides a gigaseal stably even if test cells have different properties,05-26-2011
20100252429ION-SELECTIVE ELECTRODE - A five-part electrode device, including a membrane formed in situ, which is useful in automated clinical chemistry analyzers, and the method of forming a direct solid state connection to the membrane eliminating the need for the use of an internal reference electrode requiring internal filling solutions.10-07-2010
20110036713BIOSENSOR - A biosensor can supply a sample solution accurately and easily, and includes a capillary for collecting a sample solution and analyzes a specific substance in the sample solution, an air hole, and at least two supply ports, i.e., a sample supply port and an auxiliary sample supply port, so that supply of the sample solution can be performed from either of the supply ports. Even when the sample supply port is closed up with a fingertip or the like and supply of the sample solution is stopped, the sample solution can be quickly supplied from the other auxiliary sample supply port.02-17-2011
20110036712ANALYZING SYSTEM - The present invention relates to an analysis system including a laser beam oscillator 02-17-2011
20120080312BIOMOLECULES DETECTION METHOD AND BIOMOLECULES DETECTION CHIP - A biomolecules detection chip which detects a detection target biomolecule by an electrochemical response measurement, the chip including: a chamber which is able to accommodate either a standard solution containing an electrochemically reactive agent having a binding capacity to the detection target biomolecule, or a sample solution containing a sample material and the electrochemically reactive agent; a liquid introduction device which introduces the standard solution or the sample solution into the chamber; an electrochemical response measurement device which measures an electrochemical response of either the standard solution or the sample solution accommodated in the chamber; and a liquid ejection device which ejects either the standard solution or the sample solution from the chamber.04-05-2012
20110266149ELECTROCHEMICAL SENSOR MODULE - A sensor module includes a flexible linkage; an analysis cell housing; a member anchor; a piercing member; and an electrode arrangement. The analysis cell housing defines an analysis cell and a passageway providing access to the analysis cell from a sample port of the analysis cell housing. The member anchor is configured to move relative to the analysis cell housing along the axis defined by the passageway. The piercing member is configured to slide from a retracted position to an extended position when the member anchor is moved relative to the analysis cell housing. The electrode arrangement is arranged in fluid communication with the analysis cell housing.11-03-2011
20100230284REAGENT DEVICES - A reagent device such as an electro-chemical micro-electrode sensor is provided with one or more reagent modules to carry respective reagents. The device includes respective receiving stations for receiving the reagent modules on board. The reagent modules may be tested independently before assembly of the device and hence yields are improved.09-16-2010
20120325657SENSOR DEVICE - A sensor device includes a substrate and a sensor chip held on the substrate. The substrate includes a flow channel. The sensor chip includes a plate. The plate includes a first surface and a second surface opposite to the first surface. A plurality of through holes each penetrates through the first surface and the second surface. A direction of a line segment connecting centers of any two adjacent through holes among the plurality of through holes is neither parallel nor perpendicular to the center line of the flow channel.12-27-2012
20130008786SENSOR CHIP AND STORAGE METHOD THEREOF - A sensor chip is a sensor device for measuring a property of a substance by adsorbing the substance on a surface of the sensor chip. The sensor chip includes a diaphragm having a first surface, a second surface, and at least one through hole penetrating from the first surface to the second surface. At least a part of the first surface, the second surface, and an inner wall surface of the through hole is covered with a noncrystalline solid layer including SiOX as a main component, in which substance X is an element having higher electronegativity than that of silicon.01-10-2013
20130008785METHODS FOR THE DETECTION AND DIAGNOSIS OF MALARIA USING AN ELECTROCHEMICAL SENSOR - Disclosed are apparatuses for detecting hemoglobin in patient samples. The apparatuses include a primary electrode and a reference electrode. The apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response a redox reaction catalyzed by hemoglobin. The apparatuses can detect a variety of hemoglobins, including dimeric hemoglobin associated with malaria. Also disclosed are biosensor systems including the apparatuses and methods of using the biosensor systems.01-10-2013
20130015062ELECTRODE FOR MEASURING GLYCOPROTEIN AND PREPARATION METHOD THEREOFAANM Ku; Yun HeeAACI SeoulAACO KRAAGP Ku; Yun Hee Seoul KRAANM Yang; Yong JuAACI SeoulAACO KRAAGP Yang; Yong Ju Seoul KRAANM Park; Yoo MinAACI Suwon-siAACO KRAAGP Park; Yoo Min Suwon-si KRAANM Song; Seung YeonAACI Suwon-siAACO KRAAGP Song; Seung Yeon Suwon-si KRAANM Han; Yong DukAACI Suwon-siAACO KRAAGP Han; Yong Duk Suwon-si KRAANM Kim; Moo SubAACI SeoulAACO KRAAGP Kim; Moo Sub Seoul KRAANM Yoon; Hyun ChulAACI Suwon-siAACO KRAAGP Yoon; Hyun Chul Suwon-si KR - Disclosed herein are an electrode for measuring glycoprotein and a preparation method thereof. In the electrode, cystamine is bound to the electrode surface, and boronic acid is conjugated to the cystamine. Thus, an increased amount of boronic acid can be bound to the electrode surface, so that the amount of glycoprotein can be more accurately measured using the electrode.01-17-2013
20100170791BIOSENSOR AND READOUT METER - The present invention relates to a biosensor for selectively performing quantitative analysis on a specific substance contained in a biological sample and a readout meter using the same. The inventive biosensor comprises an electrode for recording identification information of the biosensor thereon. The electrode has an electrode pattern and a plurality of contact points formed thereon according to the identification information, and the identification information is recorded on the electrode based on the ratio of resistances between the plurality of contact points. According to the present invention, various items of identification information such as in07-08-2010
20100170790BIOSENSOR - A sensor includes a diaphragm having a through-hole (07-08-2010
20100170789Microanalytical chip - Provided is a microanalytical chip that is capable of controlling sequential sending of a plurality of solutions of mutually different viscosities and interfacial tensions. The microanalytical chip includes: a main conduit including a detecting portion and/or a reacting portion; a first introduction conduit and a second introduction conduit for introducing a solution to the main conduit from a further upstream position than the detecting portion and the reacting portion; and a third introduction conduit for introducing a. solution to the main conduit, wherein W207-08-2010
20100170788ELECTROSENSING ANTIBODY-PROBE DETECTION AND MEASUREMENT SENSOR USING CONDUCTIVITY PROMOTION BUFFER - A sensor system for electrosensing an antigen in a test sample is disclosed. The sensor system has two electrodes electrically disconnected and physically separated from each other, and a layer of antibody is immobilized on the surface of the electrodes. The antibody has specific binding reactivity with the antigen. Conductivity promotion molecules suspended in a buffer solution may be distributed over and/or between the antibody-populated electrodes for improving electrical conductivity characteristics across the two electrodes. The antibody captures the antigen present in the test sample mixed in the buffer solution that comes into contact with the antibody-populated electrodes. This alters the electrical conductivity characteristic across the two electrodes in which an amount representative of the altering provides an indication for electrosensing of the antigen.07-08-2010
20080251378Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate.10-16-2008
20080251377Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate.10-16-2008
20080237038Biostrip - The invention discloses a biostrip for the determination of the health condition or disease infection of an organism. The biostrip of the invention comprises at least an insulating baseboard and a capillary channel. Said insulating baseboard has at least one surface and a printed electrode is disposed on the surface. Moreover, said capillary channel is disposed above the insulating baseboard and has at least two ends on which at least one fixation reaction area and an exhaust channel of at least one direction are disposed respectively. The exhaust channel is formed by making use of the thickness and the shape of the back gum. Therefore, the biostrip of the invention can retain the advantage of the siphon type test strip of requiring a micro-amount of sample and also avoid the complicated production process thereof.10-02-2008
20090065355BIOSENSOR CAPABLE OF SIMULTANEOUS DETECTION OF SUBSTRATE BINDING AND REACTION PRODUCT - An object of the present invention is to provide a biosensor that can detect binding of a compound with a functional protein and then assay a reaction product derived from the activity of the functional protein again. The present invention provides a biosensor for detecting a test molecule specifically binding to a physiologically active substance, which comprises; (1) (a) a first reaction region on which the physiologically active substance has been immobilized for performing a binding reaction between the physiologically active substance and the test molecule and a physiologically active reaction caused by the physiologically active substance, and (b) a second reaction region on which a molecule that specifically binds to a reaction product resulting from the physiologically active reaction has been immobilized for performing a binding reaction between the reaction product and the molecule that specifically binds to the reaction product, in the same area; and (2) an assay region for detecting changes in the binding reaction in the first reaction region and in the binding reaction in the second reaction region.03-12-2009
20130092535LIQUID-DEVELOPING SHEET - This invention is a liquid-developing sheet comprising a liquid-accepting layer at least on one surface of a substrate, wherein said liquid-accepting layer contains a binder and a block copolymer comprising blocks of ethylene oxide units and blocks of alkylene oxide units with 3 or more carbon atoms. This invention can provide a liquid-developing sheet for a biosensor, which shows stable liquid developability even at high temperature and high humidity and is good in the adhesion between the liquid-accepting layer and the substrate. If the liquid-developing sheet of this invention is used, the accuracy of measurement by the biosensor can be enhanced.04-18-2013
20130112557Handheld Blood Glucose Monitoring Device With Messaging Capability - A patient monitoring network pertaining to blood glucose and other analyte measurements includes wireless blood glucose or other analyte measuring devices and a networked computer or server. Each monitoring device is associated with a patient and is configured to measure the glucose level or other analyte from a given blood sample via inserted test strips, transmit the measurements to the networked computer, and display received messages. The blood glucose monitoring device includes means for substantially reducing factors that could affect the glucose measurement such as thermal and RF interference.05-09-2013
20130140176ELECTRODE ARRANGEMENTS FOR BIOSENSORS - The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode.06-06-2013
20080202928MULTI-LAYER STRIP FOR USE IN MEASURING BIOLOGICAL MATERIAL AND SYSTEM FOR MEASURING BIOLOGICAL MATERIAL - The multi-layer strip for use in measuring biological material and the system for measuring a biological material are provided, wherein the multi-layer strip includes a stack of a plurality of strips, each having a flow channel and a reaction unit, and the strips may react with specific materials contained in a biological material injected into the multi-layer strip, whereby Thus, it is possible to quantitatively analyze various materials contained in a biological material and to optically and electrochemically measure and quantitatively analyze various materials in a biological material.08-28-2008
20130186754BIOSENSOR CAPACITOR - A biosensor capacitor, including a dielectric layer; a first metal layer in the dielectric layer; a passivation layer over the dielectric layer and the first metal layer; an isolation layer over the passivation layer; a probe DNA electrode connected to the first metal layer; a counter electrode connected to the first metal layer wherein the counter electrode forms an enclosure around the probe DNA electrode; and a bond pad connected to the first metal layer.07-25-2013
20120024700SENSOR DEVICE AND MANUFACTURING METHOD - Disclosed is a sensor device (02-02-2012
20120073967APPARATUS FOR MEASURING BIOMATERIAL AND METHOD FOR MANUFACTURING SAME - The present invention relates to an apparatus for measuring biomaterial and a method for manufacturing thereof. The apparatus of the present invention comprises: a first substrate having a recess in one side thereof; a second substrate having a plurality of reaction electrodes where a biochemical reaction of a biomaterial occurs, and a plurality of delivery electrodes delivering signals from the reaction to a detector; and reaction reagents located in the recess causing the reaction with the biomaterial. The second substrate is attached to the first substrate such that a portion of the recess forms a sample-inlet, the recess cooperates with at least one edge of the second substrate to form at least one vent slit, and the reaction electrodes are directed toward the recess. Such apparatus of the present invention enables air in the capillary to be thoroughly and quickly discharged to the outside with biomaterial-introduction, thereby increasing the speed of the biomaterial-introduction.03-29-2012
20120085643ELECTROLYTIC CELL AND METHOD OF USE THEREOF - In one embodiment of the present invention an electrolytic cell is provided comprising a containment vessel; a first electrode; a second electrode; a source of electrical current in electrical communication with the first electrode and the second electrode; an electrolyte in fluid communication with the first electrode and the second electrode; a gas, wherein the gas is formed during electrolysis at or near the first electrode; and a separator; wherein the separator includes an inclined surface to direct flow of the electrolyte and the gas due to a difference between density of the electrolyte and the combined density of the electrolyte and the gas such that the gas substantially flows in a direction distal to the second electrode.04-12-2012
20120085642POLAROGRAPHIC INSTRUMENT SYSTEM FOR OXYGEN AND HYDROGEN MEASUREMENT - A system for measuring hydrogen (H04-12-2012
20130206595BIOSENSOR WITH THREE-DIMENSIONAL STRUCTURE AND MANUFACTURING METHOD THEREOF - The present invention relates to a biosensor which is formed with a three-dimensional structure using 3D molded interconnect device (MID) technology and a manufacturing method thereof. The present invention provides a biosensor in which reactive electrodes and signal transfer parts are formed in a three-dimensional structure on a surface of a polymer using the 3D MID technology, and a manufacturing method thereof.08-15-2013

Patent applications in class Biological material (e.g., microbe, enzyme, antigen, etc.) analyzed, tested, or included in apparatus

Patent applications in all subclasses Biological material (e.g., microbe, enzyme, antigen, etc.) analyzed, tested, or included in apparatus