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Particulate treating agent carried by breathed gas

Subclass of:

128 - Surgery

128200240 - RESPIRATORY METHOD OR DEVICE

128203120 - Means for mixing treating agent with respiratory gas

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DocumentTitleDate
20110174305Device for Dispensing a Plurality of Unitary Doses of Dry Powder, and Inhaler Comprising Such Device - Device for dispensing a plurality of unitary doses of dry powder, comprising: 07-21-2011
20130042864DRY POWDER INHALER - The present invention provides a dry-powder inhaler device comprising: a casing; an air inlet located at a first terminus of the casing; a powder delivery port located at a second terminus of the casing, which is positioned distal to the air inlet; and an elongated assembly located within an interior of the casing. A first terminus is located proximally to the air inlet, a second terminus is located proximally to the powder delivery port, and the assembly is fitted within the casing such that said assembly partially rotates therein about a single axis. The assembly has at least one compartment containing dry-powder, which is located proximally to the second terminus. The compartment with a dry-powder comprises a porous structure encasing the dry-powder; whereby airflow through the device causes the assembly to partially rotate within the casing about a single axis and release the dry-powder in the airflow.02-21-2013
20100059051INHALER - The invention relates to an inhaler (03-11-2010
20130025593Dry powder inhaler - It has a complex shaped hollow body with front mouthpiece (01-31-2013
20130074841DISPENSER FOR POWDERED COMPOSITIONS CONTAINED IN A SEPARATE PACK - The invention relates to a dispenser (03-28-2013
20120167881DRY-POWDER INHALER - An inhaler for delivering dry-powder medicament to a patient from an open blister pocket of a blister pack. The blister pack is in the form of a flexible elongate strip including a base sheet having a plurality of recesses spaced along its length and a cover sheet peelably sealed to the base sheet to define a plurality of blister pockets each containing a measured dose of the medicament. The inhaler also includes a housing for enclosing used and unused portions of the blister pack together with the medicament dispensing mechanism. The housing defines internal transverse walls extending in the width direction of the blister pack for isolating the used portion of the cover sheet from the unused portion of the blister pack.07-05-2012
20090194105INHALER - An inhaler (08-06-2009
20100012120INHALATION DEVICE FOR DRUGS IN POWDER FORM - To provide an inhalation device which has improved use properties, particularly advanced moisture protection while in use, an inhalation device (01-21-2010
20090090361INHALATION DEVICE - A dry inhaler system includes a vibrating mechanism. A supply of a dry powder is operatively coupled to the vibrating mechanism. A power source communicates with the vibrating mechanism. A sensor communicates with the vibrating mechanism. A feedback control communicates with the sensor and the power source. The feedback control controls power delivered to the vibrating mechanism relative to information provided by the sensor about the performance of the vibrating mechanism.04-09-2009
20100083963MEDICATION HOLDER - A portable medication holder is disclosed for discharging liquid agent into an air stream. The holder comprises a housing having a first wall and a second wall with the walls movable relative to each other. The second wall may be moved between a closed position and an open position wherein an air pathway is open. The holder has evaporation means to assist in evaporation of the liquid agent into air in the air pathway which flows through a medication discharge chute to a user. The device also includes opening means for opening the medication container and releasing the liquid agent to the air pathway and one or more one-way valves to provide uni-directional air flow for one or both of the inspiratory air and expired air. The liquid agent is preferably methoxyflurane. The device may include an auxiliary gas pathway for delivery of a gas such as oxygen. It may also include an auxiliary air inlet for varying the concentration of inhaled agent. The holder is preferably sealed against the external environment. The holder may include a lanyard adapted to activate relative movement between the walls. It may also include a rip seal opening for one end and a deformable cap which may be sprung clear of the medication discharge chute by impact against a surface.04-08-2010
20090235931UNIT DOSE DRY POWDER INHALER - A unit dose dry powder inhaler includes a chamber housing containing a powder dispersion chamber. A chamber tube extends from the dispersion chamber into the mouthpiece. A cover or cup is rotatably attached to the chamber housing. A dose of a dry powder is contained at a powder location in the chamber housing. An air passageway leading from the powder location to the dispersion chamber is closed off by the cover. When the cover is rotated to an open position, the air passageway is opened. The user inhales on the mouthpiece drawing air through the powder location, the air passageway, the dispersion chamber and the chamber tube, through the mouthpiece and into the users lungs. The unit dose of dry powder is stored directly in, or is part of, the inhaler.09-24-2009
20100071691LIQUID MEDICINE RESERVOIR AND DISCHARGING DEVICE FOR LIQUID MEDICINE TO BE INHALED - A liquid medicine reservoir that supplies liquid medicine to a liquid-medicine discharging portion via a communicating portion includes a cylindrical body configured to hold the liquid medicine therein, a first sealing portion to which the communicating portion is connected, the first sealing portion sealing the cylindrical body, and a second sealing portion configured to seal an end of the cylindrical body opposite the first sealing portion. At least one of the first sealing portion and the second sealing portion move relative to each other in accordance with the amount of liquid medicine. A substance configured to inhibit discharging of the liquid medicine is stored in a space in the cylindrical body that is on an inner side of the second sealing portion and that is separate from the liquid medicine.03-25-2010
20100083964DISPENSER DOSE COUNTER MECHANISM - An apparatus for counting doses of a dispenser is provided which includes a housing for releasably attaching to the dispenser; and, a dose counter operatively connected to the housing or the dispenser. The dose counter displays indicia relating to doses of the dispenser. The dose counter may be manually adjusted or configured to be automatically adjusted to permit counting of the number of times the housing is separated from the dispenser. The number of separations will indicate the number of doses administered by the dispenser. Advantageously, with the subject invention, a dose counter is provided which counts doses separately from the actuation of the dispenser. As will be appreciated by those skilled in the art, the invention may apply to various dispensers, but is particularly well-suited for use with inhalers.04-08-2010
20130206141INHALER FOR DELIVERY OF A POWDER FORMULATION FROM A BLISTER STRIP - An inhaler for delivery of a powder-form inhalation formulation from a blister strip has a plurality of blister pockets and uses a pivotable mouthpiece cover to move the blister strip onward.08-15-2013
20120174923Unit Dose Capsules and Dry Powder Inhaler - Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece.07-12-2012
20100163042INHALATION DEVICE - The present invention relates to an inhalation-activatable device for administration of medicament in powder form to the respiratory system of a patient.07-01-2010
20090314291MEDICAMENT DISPENSER - A medicament dispenser device suitable for the delivery of medicament powder from an open blister pocket of at least one blister pack, the dispenser device comprises 12-24-2009
20130032146MODIFIED AIR DELIVERY APPARATUS, SYSTEM, AND METHOD - A system, method, and apparatus for modified air delivery. A formable mask having an oxygen supply port and exhaled air removal components for the delivery of modified air to a user. An oxygen delivery system uses the formable mask and oxygen supply components. Oxygen supply components include a flow rate throttling valve and an O2 reservoir to conserve O2 use and insure O2 availability to a patient. The system modifies the air for delivery using an air modification module to condition the air for delivery of aerosolized particles to the user.02-07-2013
20130032145DRY POWDER INHALER - A dry-powder inhaler device comprising an air inlet (02-07-2013
20100043792INHALER AND METHOD OF CONTROLLING THE SAME - To maintain an inner pressure of a tank within an appropriate range on a constant basis even when medicine is dispensed over plural times in multidose in a simple inhaler in which the inner pressure is not measured. A cartridge (02-25-2010
20130133652A FLUID DISPENSER DEVICE - A fluid dispenser device including a body, an elongate flexible strip supporting a plurality of reservoirs, each containing a dose of fluid or powder; an reservoir-opening mechanism for opening a reservoir on actuation; a first displacement mechanism for causing the flexible strip to advance before, during and/or after actuation, so as to bring a full reservoir into register with the reservoir-opening mechanism; and a second displacement mechanism for displacing a full reservoir against the opening mechanism each actuation. The leading end of the flexible strip is fastened to a rotary receiver element, the receiver element including a set of peripheral teeth that co-operates with a movable traction member, a stressed spring acting on the movable traction member so as to displace it, the displacement of the movable traction member causing the receiver element to turn, such that the receiver element exerts a traction force on the elongate strip.05-30-2013
20090159080PARTICLE DISPERSION CHAMBER FOR NASAL NEBULIZER - A nebulizer and a method of breathing using the nebulizer is described. The nebulizer and breathing techniques are capable of delivering medicament into the sinus cavity of a user.06-25-2009
20090120436POWDER MEDICINE ADMINISTERING APPARATUS - A powder medicine administering apparatus includes: an upper body including a lower surface, and a medicine storage chamber having an upper opening portion opened on the lower surface; a lower body including an upper surface, and a medicine receiving chamber which has a lower opening portion, and which is recessed in a downward direction from the lower opening portion. The lower body is relatively slid with respect to the upper body so that the lower surface of the upper body is slidably moved on the upper surface of the lower body to be switched between a connection state and a non-connection state. The medicine receiving chamber is arranged to be moved in a one section from the standby position to the discharge position so that entire of the lower opening portion of the medicine receiving chamber is within the upper opening portion of the upper body.05-14-2009
20100006096Methods and apparatus for delivering aerosolized medication - A pulmonary drug delivery device having one or more vortexing elements which impart beneficial flow characteristics to an inspiratory air flow carrying a medicament into the patient's lungs.01-14-2010
20090090360MOUTHPIECE FOR A DEVICE FOR DISPENSING A FLUID PRODUCT - A mouthpiece (04-09-2009
20130047986STORAGE SYSTEM FOR POWDERED PHARMACEUTICALS, AND INHALER EQUIPPED WITH THIS SYSTEM - In order to improve the administration of powdered pharmaceuticals, the invention proposes a storage system for powdered pharmaceuticals, in particular for use or integration in a powder inhaler, for receiving a multiplicity of doses of at least one medically active substance, with at least two storage spaces (02-28-2013
20130047985DRY POWDER INHALER ASSEMBLY AND CONTAINERS - The present disclosure provides dry powder inhalers, containers for carrying a dose of dry powder medicament particles for dry powder inhalers, and a hinge that, while enjoying broader applicability, may be used in such inhalers.02-28-2013
20100000530Dispersing Unit - A dispersing unit for a powder inhaler comprises a mouthpiece with an annular channel for the delivery of a stream of particles. The annular channel has an axial inlet, and an axial outlet adjoined by an annular deflection chamber in which the axially incoming stream of particles is deflected to a predominantly radial direction of flow. The deflection chamber is adjoined in the axial direction by a rotation chamber with a circular peripheral wall and an axial outlet.01-07-2010
20090095294DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM - A dry powder inhaler for delivering medicament to a patient includes a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and an aeroelastic element in the chamber and associated with a dose of powdered medicament. A tensioning assembly is configured to apply a first amount of tension to the aeroelastic element such that the aeroelastic element is capable of vibrating in response to airflow through the chamber so as to aerosolize the dose of powdered medicament.04-16-2009
20100089395SUPPLEMENTAL OXYGEN DELIVERY SYSTEM - A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 04-15-2010
20120304991DRUG PRODUCTS AND DRY POWDER INHALERS WITH MULTIPLE RESERVOIRS - Various embodiments of the present invention provide drug products and dry powder inhalers and powder dispensers with multiple reservoirs. Several embodiments provide a drug product comprising a dry powder inhaler and at least one dose of at least one active pharmaceutical agent; wherein the dry powder inhaler comprises at least two reservoirs. Other embodiments provide for a powder dispenser which includes a first powder reservoir having at least one first opening, and a second powder reservoir having at least one second outlet opening, the second outlet opening being spaced from the first outlet opening.12-06-2012
20090293873POWDER DELIVERY DEVICES - A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising: a substance supply unit for supplying a dose of substance to be delivered to the nasal cavity of the subject, she substance supply unit including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the substance supply unit; and a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the substance supply unit and through which the subject in use exhales such as to entrain substance from the container chamber and deliver the same through the nosepiece, and at least one temperature modifier for reducing a temperature of the exhaled air flow such as to reduce the absolute humidity thereof.12-03-2009
20120222675DISPENSING DEVICE, STORAGE DEVICE AND METHOD FOR DISPENSING POWDER - A dispensing device, and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle, the storage chamber and duct or nozzle being formed of a one-piece construction.09-06-2012
20130061851DELIVERY DEVICE AND RELATED METHODS - A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. A disc element may be arranged to move between a closed position in which the disc element closes the opening of the dose chamber, and an open position in which the disc opens the dose chamber to permit introduction of the dose into the air path of the device. Movement of the disc element from the closed position to the open position may be in a direction away from the dose chamber (e.g., a puller may engage the disc element and pull the element away from the chamber) and may leave a substantial portion of the dose in the dose chamber.03-14-2013
20120192865Unit Dose Capsules and Dry Powder Inhaler - Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece.08-02-2012
20100126508Indicating device for aerosol container - An indicating device suitable for indicating the number of metered dosages that have been dispensed from or remain in a container including a base member, a cap member moveably connected to the base member, an indicator member rotatably mounted to one of the cap member and base member and a drive member. The indicator member comprises a first stop member, and the drive member comprises a second stop member. The first stop member engages the second stop member as the indicator is moved to the final position. The engagement between the first and second stop members prevents the drive member from being rotated about the second axis. In another preferred embodiment, an inhalation device for dispensing metered dosages of medicaments from a container includes a container having a predetermined number of metered doses and the indicating device. A method for indicating the number of metered dosages of medicaments dispensed from or remaining in the container is also provided.05-27-2010
20090235930UNIT DOSE DRY POWDER INHALER - A unit dose dry powder inhaler has a dose unit within an inhaler housing. As the dose unit is pushed into the inhaler housing, a container on the dose unit is opened, releasing a pharmaceutical powder into the housing. The user inhales on a mouthpiece, drawing the powder and air into a dispersion chamber. The powder disperses in air, and the powder/air mixture is inhaled. The inhaler is inexpensive, compact, and simple to use.09-24-2009
20090235929POWDER INHALERS - The invention relates to a powder inhaler for administering moisture-sensitive pharmaceutical formulations.09-24-2009
20090013998INHALABLE TIOTROPIUM AND CONTAINER THEREFOR - A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.01-15-2009
20090013997INHALANT EXPOSURE SYSTEM - An inhalant exposure unit and system that provides controlled flow of inhalant to an animal with a breathing system that provide controlled exposure of inhalant, minimized breathing of exhaled air and control of exhaust flow.01-15-2009
20120111328DRY POWDER INHALERS - A dry powder inhaler (05-10-2012
20120111327Does Unit, Pack of Dose Units and Inhaler for Inhalation of Combination of Drugs - The invention relates to a dose unit for a dry powder inhaler comprising:—a dose carrier including a plurality of pockets (05-10-2012
20120111326Dosing Device for Generating a Gas Flow with an Active Substance Finely Dispersed in the Latter - (1) Dosing device for generating a gas flow with an active substance finely dispersed in the latter. (2) The invention relates to a dosing device for generating a gas flow with an active substance (05-10-2012
20120234322DRY POWDER INHALER WITH FLUTTER DISPERSION MEMBER - A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.09-20-2012
20080295832Inhaler with Mouthpiece Having a Microbiological Protective Function - The present invention relates to an inhaler with a novel mouthpiece having a microbiological protective function. The inhalers are used for administration of a pharmaceutical substance, substance formulation or substance mixture.12-04-2008
20080295830Tool and method for customized inhalation - A method for designing and/or customizing the treatment or for treating by inhalation of a patient suffering from a respiratory or non-respiratory disease including the steps of presenting a patient suffering from the disease; determining the kind of disease of the patient; prescribing at least one drug and/or gas and at least one kind of device to be used for administrating the drug or gas; inputting into a processing element, data chosen among the drug and/or prescribed gas and drug particle size obtained with the prescribed device; inputting into the processing element at least one patient characteristics of the patient; inputting into processing element at least one morphology and/or ventilatory condition of the patient; running a code in the processing element using the input data and conditions thereby calculating a flow and/or deposition characteristics customized to the patient.12-04-2008
20130206142INHALER - An inhaler, the inhaler including a body (08-15-2013
20120111325Low Dose Pharmaceutical Powders for Inhalation - The invention relates to a method of delivering an agent to the pulmonary system of a compromised patient, in a single breath-activated step, comprising administering a particle mass comprising an agent from an inhaler containing less than 5 milligrams of the mass, wherein at least about 50% of the mass in the receptacle is delivered to the pulmonary system of a patient. The invention also relates to receptacles containing the particle mass and the inhaler for use therein.05-10-2012
20110186047Dry Powder Inhalers with Rotating Piercing Mechanisms and Related Devices and Methods - Dry powder inhalers with rotatable piercing mechanisms facilitate the use of dose container assemblies having dose containers arranged in concentric rows. A piercing mechanism is operably associated with the dose container assembly and is configured to pierce sealants that seal a dose container. The piercing mechanism is rotatable such that it can serially alternate between the two rows of dose containers. The piercing mechanism includes a rotatable drum, an elongate piercing member, and a biasing member operably associated with the piercing member. The rotatable drum has an open end, an opposite closed end, and a cylindrical wall that extends from the closed end and terminates at the open end. The closed end includes an aperture formed therein in a location adjacent to the wall. The elongate piercing member is extended and retracted through the aperture to pierce the sealants of a dose container.08-04-2011
20110277763Combination Unit Dose Dispensing Containers - Dosage forms containing pharmaceutical compositions for use in devices to produce a spray or mist delivery of the compositions include dosage blister compartments and a dispensing blister compartment, wherein crushing of the compartments delivers the compositions in a desired spray pattern. Certain dosage forms include a plurality of dosage chambers each containing a component or a portion of a pharmaceutical composition, the contents of which are mixed or combined just prior to or during administration.11-17-2011
20120285451TWO-PIECE METAL CAPSULE FOR ACCOMMODATING PHARMACEUTICAL PREPARATIONS FOR POWDER INHALERS - The invention relates to novel two-piece metal capsules for accommodating pharmaceutical preparations to be used in powder inhalers as well as a method for producing said capsule. The inventive capsules are particularly impermeable to steam and oxygen.11-15-2012
20110132356COMPOSITIONS FOR PULMONARY DELIVERY OF LONG-ACTING B2 ADRENERGIC RECEPTOR AGONISTS AND ASSOCIATED METHODS AND SYSTEMS - Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting β06-09-2011
20100212667DRUG CAPSULES FOR DRY POWDER INHALERS - A method of filling a drug capsule (08-26-2010
20110297151INHALER - An inhaler, particularly a powder inhaler, for administering a medicament in the form of inhalable substances, substance formulations or mixtures, with a mouthpiece (12-08-2011
20090205657Pre-metered dose magazine for dry powder inhaler - A dry powder inhaler including a housing having a mouthpiece and a delivery passageway connected to the mouthpiece, a magazine positioned within the housing and including a plurality of reservoirs for holding doses of dry powder, and wherein the magazine is movable within the housing so that the reservoirs are sequentially positioned within the delivery passageway of the housing upon movement of the magazine, a cover connected to the housing and movable to open and close the mouthpiece of the housing, and a rake connected to the cover, extending into the housing and engageable with the magazine so that, upon the cover being moved to open the mouthpiece, the rake moves the magazine and causes one of the reservoirs of the magazine to be positioned within the delivery passageway.08-20-2009
20090205656POWDER INHALER - The subject invention provides a powder inhaler enabling the user to complete powder drug inhalation with fewer steps, for improved user convenience.08-20-2009
20080236579METHOD FOR THE ADMINISTRATION OF AN ANTICHOLINERGIC BY INHALATION - An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1, √{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 μm, and a method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 pm to 500 μm, the method comprising actuating an inhaler a flow resistance of about 0.01 to 0.1 √{square root over (kPa)} min/L containing the inhalable powder.10-02-2008
20100101572METERED DOSE INHALER FOR AEROSOL - A metered dose inhaler for aerosol comprises an actuator (04-29-2010
20120097162DRY-POWDER INHALER - An inhaler for delivering dry-powder medicament to a patient from an open blister pocket of a blister pack. The inhaler includes a housing for enclosing used and unused portions of the blister pack together with a medicament dispensing mechanism. The inhaler also includes a manifold through which air can be drawn in use of the inhaler, the manifold including an air inlet for receiving external air, at least one medicament aperture for communicating with an opened pocket of the blister pack to enable entrainment of the medicament by the air drawn through the manifold, and an air outlet for delivery of the entrained medicament to the patient. The medicament dispensing mechanism includes a guide surface for guiding the cover sheet of the unused portion of the blister pack. The manifold and the guide surface are defined by separate components of the inhaler.04-26-2012
20120097161DRY-POWDER INHALER - An inhaler for delivering dry-powder medicament to a patient from an open blister pocket of a blister pack. The blister pack has a plurality of blister pockets spaced apart in a length direction of the pack and each containing a measured dose of the medicament. The inhaler includes a housing for enclosing used and unused portions of the blister pack together with a medicament dispensing mechanism for opening the blister pockets of the blister pack. The inhaler also includes a manifold through which air can be drawn in use of the inhaler, the manifold including an air inlet for receiving external air, at least one medicament aperture for communicating with an opened pocket of the blister pack to enable entrainment of the medicament by the air drawn through the manifold, and an air outlet for delivery of the entrained medicament to the patient.04-26-2012
20100101573OSCILLATING POSITIVE EXPIRATORY PRESSURE DEVICE - An oscillating positive expiratory pressure apparatus having a housing defining a chamber, a chamber inlet, a chamber outlet, a deformable restrictor member positioned in an exhalation flow path between the chamber inlet and the chamber outlet, and an oscillation member disposed within the chamber. The deformable restrictor member and the oscillation member are moveable between an engaged position, where the oscillation member is in contact with the deformable restrictor member and an disengaged position, where the oscillation member is not in contact with the deformable restrictor member. The deformable restrictor member and the oscillation member move from the engaged position to the disengaged position in response to a first exhalation pressure at the chamber inlet, and move from the disengaged position to an engaged position in response to a second exhalation pressure at the chamber inlet.04-29-2010
20090320837DRY POWDER INHALERS - A dry powder inhaler comprises: a cyclone chamber having a cyclone chamber outlet (12-31-2009
20080283056DISPENSING DEVICE - A dispensing device having a storage device and an air pump for dispensing a medical formulation. The storage device comprises multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert.11-20-2008
20090145433APPARATUS FOR DISPENSING A POWDERED COMPOSITION INTO THE AERODIGESTIVE TRACT - An apparatus for dispensing a powdered composition into the aerodigestive tract comprises a dispensing apparatus for dispensing an amount of powdered material and an inhalation attachment apparatus connected to the dispensing apparatus. The amount dispensed by the dispensing apparatus may be a restricted amount. The inhalation attachment apparatus comprises a channel for receiving the dispensed powdered material from the dispensing apparatus, a plurality of apertures for mixing air with the powdered material, and an outlet aperture at an end of the channel for expelling the powdered material. Air is draw in through the outlet apertures upon inhalation by a user at the outlet aperture. The air mixes with the powdered material dispensed from the dispensing apparatus. The powdered material is dispersed and accelerated by the air, and expelled into and through the mouth of a user, and thereby deposited into the aerodigestive tract.06-11-2009
20090151722Inhaler - An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises an unused and a used blister compartment separated by a wall which may be moulded integrally with the housing of the device.06-18-2009
20090151723Device for dosed administration of sprayable substances - The invention relates to a device for dosed administration of sprayable substances, in particular aerosols, with an electronic unit for recording the administrations, and a with a first housing part that forms a seat for a container, which contains the sprayable substance and has a valve. It is characterized by a second housing part, which is movable relative to the first housing part and has an actuating part for acting on the valve in order to actuate the valve for administration of the sprayable substance, the electronic unit for recording the administrations of the sprayable substance including a switch that is actuated by the relative movement of first and second housing part.06-18-2009
20090095293DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION - The present invention provides a novel dry powder inhalation system suitable for transpulmonary administration. The dry powder inhalation system of the invention characterized by using a combination of: 04-16-2009
20090007907Inhaler - An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises an unused and a used blister compartment separated by a wall which may be moulded integrally with the housing of the device.01-08-2009
20100078022INHALERS WITH AIRWAY DISKS HAVING DISCRETE AIRWAY CHANNELS AND RELATED DISKS AND METHODS - Dry powder inhalers include radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.04-01-2010
20100078021Dry Powder Inhalers with Dual Piercing Members and Related Devices and Methods - A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.04-01-2010
20090308391Dry Powder Inhaler and System for Drug Delivery - A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.12-17-2009
20090308390Dry Powder Inhaler and System for Drug Delivery - A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.12-17-2009
20090308392Dry Powder Inhaler and System for Drug Delivery - A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.12-17-2009
20090205658DEVICES AND METHODS FOR DELIVERY OF A THERAPEUTIC AGENT THROUGH A PNEUMOSTOMA - A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma and a drug delivery device for pneumostoma care. The drug delivery device includes a therapeutic agent dispenser for supplying a therapeutic agent and a propellant at positive pressure, a tube for entering the pneumostoma and a limiting device for limiting the depth of insertion of the tube into a pneumostoma. The drug delivery device may be used to introduce therapeutic agents into the pneumostoma for direct treatment of the pneumostoma, treatment of the lung by way of collateral ventilation, and/or treatment of non-lung tissues by diffusion into the bloodstream.08-20-2009
20100126507MULTI-DOSE INHALER DEVICE - The present invention provides an inhaler device (05-27-2010
20110168178POWDER INHALATION DEVICE - A powder inhaler comprising: a body (07-14-2011
20100000532Method for displaying dosage indicia - A method for displaying dosage indicia includes engaging a dispenser housing with a container in an engaged position, moving the container relative to the dispenser housing along a longitudinal axis while the container and the dispenser housing are in the engaged position, moving a valve between a closed position and an open position in response to moving the container relative to the dispenser housing and thereby dispensing metered dosages of substance when the valve is moved to the open position, moving the container relative to the dispenser housing to a disengaged position, moving an indicating portion with the container as the container is moved relative to the dispenser housing between the engaged and disengaged positions, and moving the indicator member relative to the container along the longitudinal axis while the container is in the engaged position.01-07-2010
20090283095FLUID-PRODUCT DISPENSING DEVICE - An inhaler comprising: a body; at least one cover element that is movable between a closed position and an open position; individual reservoirs formed on a reservoir substrate; movable support means that receive said reservoir substrate and that are displaceable between a non-dispensing position and a dispensing position; and an indicator device for indicating doses that have been dispensed or that remain to be dispensed, said indicator device comprising: a rotary indicator element that supports indicator means, such as numbers, colors, and/or symbols; and an actuator that co-operates with said movable support means so as to cause said rotary indicator element to turn when said movable support means return from the dispensing position to the non-dispensing position.11-19-2009
20090283094MEDICINE EJECTION DEVICE - In a medicine ejection device for administering a medicine to the throat, bronchi or lungs, the air flow path to which the medicine has stuck is to be kept in clean state in a simple configuration. The medicine ejection device which ejects a medicine to be inhaled by a user via a suction port, including a flow path member linked to the suction port and capable of forming an air flow path in which the medicine is guided by the inhalation by the user to the suction port, and an internal wall face constituting member which is intended for formation of the internal wall of the air flow path and allows detachable fitting in the flow path member.11-19-2009
20090293874DELIVERY DEVICE - A delivery device, e.g. an inhaler, comprises a rotatable metering member adapted to dispense a measured amount of material, a material delivery passage and a material delivery orifice and at least one actuator member adapted to move the metering member from a material retaining position to a material dispensing position. In a magazine comprising a plurality of metering members, the actuator and metering members may operate in a radial direction. A plurality of rotatable magazines may be utilized in the delivery device. The delivery device may be used to deliver a single or a combination therapy.12-03-2009
20110203586Powder Inhalers - The invention relates to a powder inhaler for administering moisture-sensitive pharmaceutical formulations.08-25-2011
20090165788DRUG CONTAINMENT SYSTEMS WITH STICKS, RELATED KITS, DRY POWDER INHALERS AND METHODS - Dry powder drug containment systems with a stick substrate and at least one dry powder receptacle or container that can be detached or opened to release dry powder in an inhaler. Related inhalers and kits of sticks are described.07-02-2009
20100006095APPARATUS AND METHODS FOR PROVIDING DRY POWDER MEDICAMENT FOR INHALATION - The application describes apparatus and methods for delivering a powdered medicament for inhalation. The medicament is put in a receptacle (01-14-2010
20080251072Inhaler Device - An inhaler device (10-16-2008
20090165789LIQUID EJECTION CARTRIDGE AND LIQUID EJECTION DEVICE - Provided are a liquid ejection cartridge and a liquid ejection device each having a simple structure capable of surely mixing a plurality of liquids. The liquid ejection cartridge according to the present invention includes a liquid ejection portion (07-02-2009
20120291782DEVICE FOR DISPENSING A PLURALITY OF UNITARY DOSES OF DRY POWDER, AND INHALER COMPRISING SUCH DEVICE - Device for dispensing a plurality of unitary doses (11-22-2012
20080283057DISPENSING DEVICE - A dispensing device having a storage device and an air pump for dispensing a medical formulation. The storage device comprises multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert.11-20-2008
20120291780BEAD-CONTAINING DRY POWDER INHALER - A dry powder inhaler includes a chamber holding a bead-like actuator to which a powdered medicament is adhered. Air is drawn into the chamber through an inlet flow channel and exits through an outlet flow channel. The bead-like actuator oscillates in response to the air flow, dislodging powdered medicament to be entrained in the air flow and delivered to the patient.11-22-2012
20080308102Manifold for Use in Medicament Dispenser - A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from said chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and the chamber inlet lie side-by-side each other such that when the open blister pocket of the blister pack is positioned adjacent thereto the airflow is directed from the chimney exit to the chamber inlet via the open blister pocket to entrain the medicament powder and enable transport thereof in the airflow from the chamber inlet to the chamber exit,12-18-2008
20080295831Inhaler vaporizer - An inhaler vaporizer consists of two parts, the first part consisting of a funnel with a top portion, a “Y” portion and a disc portion made of a porous material or a non-porous material with a multiplicity of small holes. This part is inserted into a main body portion consisting of a main body, mouthpiece and base. The internal “Y” portion is sealed to the main body portion by an O-ring. Ethyl alcohol is poured into the main body of the inhaler vaporizer, and air is drawn into the inhaler vaporizer by applying suction through the mouthpiece. This air is drawn into the “Y” cone, passes through the “Y” stem tubular portion to the bottom of the body portion of the inhaler vaporizer. The air is drawn through the alcohol, vaporizing the alcohol in the process and is then inhaled through the mouthpiece into the mouth, throat, and lungs where it interacts with affected tissue.12-04-2008
20080283054DISPENSING DEVICE - A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert by a connecting element that is moveable relative to the inserts for individually supplying air from a air pump to a respective one of the receptacles. A manually operated actuator is radially moveable to operate the air pump and to rotate the storage device to the next receptacle, and/or radially move the connecting element to individually open the respective receptacle, and to connect the pump to the respective receptacle and/or to push an insert out of the respective receptacle.11-20-2008
20080289629Nasal Delivery Devices - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container, which means are provided, for example, by providing the container in a replaceable container-containing member, by a pressure-sensitive valve which normally closes the fluid connection between the container chamber and the mouthpiece, and a temperature regulator upstream of the container chamber.11-27-2008
20080295833DISPENSING DEVICE - A dispensing device has a storage device and an air pump for dispensing a medical formulation has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert. A connecting element that is moveable relative to the cavities is provided for individually opening and supplying pressurized gas thereto for dispensing a respective dose of formulation, and the storage device has an empty, hollow or dummy receptacle into which the connecting element is engaged in a state prior to first use of the dispensing device.12-04-2008
20080264415Inhaler - An inhaler (10-30-2008
20100263668DEVICE FOR DISPENSING FLUID PRODUCT - A fluid dispenser device comprising a body (10-21-2010
20080264416Method of Treating Diabetes Mellitus in a Patient - Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each time is consistent. A device for delivering insulin by inhalation is disclosed which device comprises a means for measuring inhaled volume and for halting inhalation at a pre-determined point. The device also comprises an adjustable means for applying various amounts of force to a container of formulation to expel different amounts of drug from the container based on the force applied.10-30-2008
20090178678RESERVOIR PRESSURE SYSTEM FOR MEDICAMENT INHALER - An inhaler includes an accurate and consistent mechanical dose metering system that dispenses dry powdered medicament in discrete amounts or doses for patient inhalation, a pressure relief system that manages pressure within a medicament reservoir of the inhaler to ensure consistently dispensed doses, and a dose counting system indicating the number of doses dispensed by or remaining in the inhaler.07-16-2009
20090178677FLUID-PRODUCT DISPENSING DEVICE - An inhaler comprising: at least one cover element (07-16-2009
20080257345Antistatic medication delivery apparatus - An aerosol medication delivery apparatus include a holding chamber having an input end and an output end and defining an interior space. In one embodiment, the holding chamber is antistatic and is made of a plastic material having a surface resistivity of between about 10E10 and about 10E12 ohm/sq. In another embodiment, a component, such as a backpiece or mouthpiece, separate from the holding chamber, is antistatic and is made of a material having a surface resistivity of between about 10E10 and about 10E12 ohm/sq. The component is connected to the holding chamber, which may or may not be antistatic. In one embodiment, the component is made of an elastomeric material. In one embodiment, at least a portion of the holding chamber and/or component is see-through. Various methods for introducing an aerosol into the holding chamber at the input end thereof and inhaling the aerosol through the output end are also provided.10-23-2008
20100139655DRY-POWDER INHALER - A dry-powder, breath-powered inhaler device comprising at least one air inlet, a flow chamber and an air outlet leading to a mouthpiece, the flow chamber further comprising at least one drug-containing volume and at least one scraping means and a rotor assembly comprising an axis and at least one blade; wherein the inhalation action of the patient applied at the air outlet causes air to enter the at least one air inlet such that the air interacts with the at least one rotor blade causing the rotor to rotate and thus generate breath-driven, relative motion between the at least one drug-containing volume and the at least one scraping means, such that fine particles of powder are released from the drug-containing volume; the arrangement being such that the air exits the flow chamber via the periphery of the flow chamber, carrying out the fine particles to the outlet to be inhaled by the patient.06-10-2010
20090025721Powder inhaler devices - An improved inhalation device is provided for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device includes a staple assembly comprising a plunger and staple that are securely and robustly coupled to one another. Embodiments of the inhalation device have a cap that prevents or reduces the amount of dust and grime entering into the device. The cap is additionally configured to prevent or reduce inadvertent and unintentional operation of the device. The body portion and first casing portion of certain embodiments of the inhalation device are sealably coupled, restricting or reducing undesirable flow pathways that have an adverse effect on the operation of the device.01-29-2009
20090025722ADAPTER FOR INHALATION APPLIANCES FOR TREATMENT OF ARTIFICIALLY VENTILATED PATIENTS - The invention relates to a device for delivery of respiratory gases in conjunction with a powder inhaler for inhaled administration of pharmaceuticals, pharmaceutical mixtures or pharmaceutical formulations to patients who are attached to respirators. The pharmaceuticals, pharmaceutical mixtures or pharmaceutical formulations are preferably administered to patients who are being artificially ventilated through a mask or via a tracheal tube under anesthesia.01-29-2009
20090025720Dry Powder Aerosolized Inhaler - This invention provides an aerosolized inhaler which enables the drug powder to aerosolize within the inhaler by breathing in the air, comprising the main body (01-29-2009
20090025719Pre-metered dry powder inhaler for moisture-sensitive medicaments - The invention discloses a dry powder inhaler for use in a treatment of respiratory disorders.01-29-2009
20090007908Inhaler - An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises a spiral wound element within the housing that receives and coils said strip of blisters that have been breached.01-08-2009
20090211577Device for Dosing and Dry Nebulization - The invention relates to a device 08-27-2009
20090320838DRY POWDER INHALER - An inhaler (12-31-2009
20090320839Indicating device - A dispensing device for use in dispensing metered dosages of substance from a container includes a dispenser housing having a support block defining a longitudinal axis and an indicator member rotatably disposed in the dispenser housing. The indicator member is rotatable about a rotation axis forming an obtuse angle with the longitudinal axis. An indicating device includes an actuator member moveable along a longitudinal direction and an indicator member rotatably mounted in the indicator housing about a rotation axis forming an obtuse angle with an axis extending in the longitudinal direction. An indicating device includes an indicator housing having an upper surface with an opening formed therein and an actuator ring having a flange moveable through the opening in a longitudinal direction. An indicator member is rotatably mounted in the indicator housing. A medicament assembly and method for dispensing a metered dose of medicament are also provided.12-31-2009
20090314292INTERACTIVE APPARATUS AND METHOD FOR REAL-TIME PROFILING OF INHALATION EFFORTS - Described herein are interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The devices can be used in a wired or wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system, to evaluate the performance of the inhalation system and/or to detect the characteristics profile of a dry powder formulation emitted from the inhalation system in use.12-24-2009
20090241949DRY POWDER INHALATION SYSTEM - Dry powder inhaler systems for pulmonary delivery of pharmaceuticals are disclosed. The dry powder inhalation systems comprise a dry powder inhalation device or inhaler and a cartridge containing a pharmaceutical formulation comprising an active ingredient for delivery to the pulmonary circulation. The present devices provide rugged devices which are reusable, use pre-metered unit dose cartridges which deliver a medicament in a liner manner, and can be disassembled for cleaning. The devices also provide a high resistance inhalation system which enables deagglomeration of dry powder particles, have a consistent airflow, are easy to manufacture and are simple and relatively easy to use.10-01-2009
20090050149Inhaler for Powdery Substances - The invention relates to an inhaler (02-26-2009
20090084380DRY POWDER INHALER - A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.04-02-2009
20090084379DRY POWDER INHALER - An dry powder inhaler is disclosed. The dry powder inhaler is designed so that a user's breath vacuums the dry powder from a well within the housing and directs the powder in a direct path to the user. This design prevents impaction and agglomeration of powder within the inhaler. A flow restrictor may be added within the inhaler to increase turbulence and thus increase dispersion of powder within the air inhaled by the user.04-02-2009
20090101144PORTABLE GAS OPERATING INHALER - The invention relates to an inhaler comprising a compressed gas, such as Heliox gas in a first chamber which is in communication with an equalization chamber having pressure lower than the pressure of the gas in the first compressed chamber and having a drug storage chamber which is detachably coupled to the equalization chamber operable such that a portion of the compressed gas from the equalization chamber fluidizes and aerosolizes the drug to produce a drug cloud and which can then be injected into a spacer where it can be inhaled by a user.04-23-2009
20090007909Inhalation device - An inhalation device for a powdery medium includes a housing having at least one medium reservoir and an outlet channel, in which a first end of the outlet channel opens out in the area of the medium reservoir and a second end is designed to lie flush on a respiration opening of a user, such that the medium stored in the medium reservoir can be inhaled by the user breathing in. A respiration assistance device is provided which can be connected releasably to the housing and from which an air stream assisting the inhalation can be delivered to the housing by a manual actuation.01-08-2009
20090211578INHALER VALVE - Rotary metering valve (08-27-2009
20090250056DRY POWDER INHALATION DEVICE FOR THE SIMULTANEOUS ADMINISTRATION OF MORE THAN ONE MEDICAMENT - The present invention relates to a dry powder inhalation device which is suitable for the simultaneous administration of a combination of pharmaceutical ingredients, wherein each pharmaceutical ingredient is packed in a separate blister of the same single dose blister strip. The medicaments that form the combination come into contact just before their exit from the mouthpiece of the device.10-08-2009
20090165790DRY POWDER INHALERS - Dry powder inhalers include an elongate body having opposing first and second outer primary surfaces with a cavity therebetween and having opposing top and bottom end portions and a disk holding a plurality of doses of a dry powder inhalable product located in the cavity of the elongate body. The inhaler also includes an inhalation port, the inhalation port configured to be in fluid communication with at least one of the discrete meted doses during use and a cover member that is pivotably attached to the elongate body so that it remains attached to the body during normal operational periods of use and moves to a first closed position to overlie the inhalation port at the bottom end portion of the body during periods of non-use and moves to a second open position away from the inhalation port during periods of use to allow a user to access the inhalation port.07-02-2009
20090250057Medicaments magazine for an inhaler, and a multi-dose powder inhaler - The invention is a medicament magazine having at least one medicament chamber for use in a powder inhaler, wherein the magazine is formed from two foil strips applied to one another and the at least one medicament chamber is formed between the foil strips. The medicament chambers have an internal structure (10-08-2009
20090241950METHOD OF TREATING DIABETES MELLITUS IN A PATIENT - The need for the delivery of insulin by injection can be reduced or eliminated by delivering an aerosolized monomeric insulin formulation. Repeatability of dosing and more particularly the repeatability of the blood concentration versus time profile is improved relative to regular insulin. The blood concentration versus time profile is substantially unaffected by specific aspects of the patient=s breathing maneuver at delivery. Further, the rate at which blood glucose is lowered is increased by the use of monomeric insulin. Particles of insulin and in particular monomeric insulin delivered to the surface of lung tissue will be absorbed into the circulatory system. The monomeric insulin may be a dry powder but is preferably in a liquid formulation delivered to the patient from a hand-held, self-contained device which automatically releases an aerosolized burst of formulation. The device includes a sensor which is preferably electronic which measures inspiratory flow and volume which measurement can be used to control the point of drug release.10-01-2009
20090255533SYSTEMS, METHODS AND APPARATUS FOR RESPIRATORY SUPPORT OF A PATIENT - Spontaneous respiration is detected by sensors. An additional amount of oxygen is administered to the lungs via a jet gas current at the end of an inhalation procedure. Breathing volume, absorption of oxygen during inhalation, and clearance of carbon dioxide during exhalation are improved. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent to avoid a collapse of the respiration paths. An apparatus including an oxygen pump can be connected to an oxygen source and includes a tracheal prosthesis that can be connected via a catheter. The respiration detections sensors are connected to a control unit for activating the oxygen pump. The tracheal prosthesis includes a tubular support body with a connection for the catheter, and the sensors are associated with the support body. The tracheal prosthesis and jet catheter are dimensioned so the patient can freely breathe and speak without restriction.10-15-2009
20090260626Inhaler for Powdery, Especially Medical Substances - The invention relates to an inhaler (10-22-2009
20110139152ANTIBIOTIC MICROPARTICLES FOR INHALATION - Powder formulations for inhalation which comprise microparticles containing an antibiotic and magnesium stearate are useful for the treatment of bacterial infections associated with certain pulmonary diseases.06-16-2011
20100175696Medicine sprayer - A body section 07-15-2010
20100154795DRY POWDER INHALER - The present invention relates to an improvement of the mouthpiece of a dry powder inhalation device wherein the medicament is packed in the blisters of single dose blister strips. According to the invention a portion of the air which enters the mouthpiece does not pass through the powder containing blister, but follows an alternative path through the mouthpiece, enabling therefore the modification of the resistance of the device in a simple and cost effective manner.06-24-2010
20120103331METER FOR FLUID OR POWDERY PRODUCT DISPENSING DEVICE - A counter including a body (05-03-2012
20100163041Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position.07-01-2010
20130213397INHALER TO DELIVER SUBSTANCES FOR PROPHYLAXIS OR PREVENTION OF DISEASE OR INJURY CAUSED BY THE INHALATION OF BIOLOGICAL OR CHEMICAL AGENTS - A dry powder inhaler may include a powder storage region, an inlet channel, a dispersion chamber, and an outlet channel. A geometry of the inhaler may be such that a flow profile is generated within the dispersion chamber that causes an actuator to oscillate, enabling the actuator when oscillating to deaggregate powdered medicament within the dispersion chamber to be aerosolized and entrained by the air and delivered to a patient through the outlet channel.08-22-2013
20130213398DRY POWDER FORMULATIONS AND METHODS FOR TREATING PULMONARY DISEASES - The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.08-22-2013
20100192950TANK OPENING DEVICE FOR FLUID PRODUCT DISPENSING DEVICE - An inhaler device having an opening device for opening an individual reservoir containing a single dose of fluid, such as powder, the reservoir including a closure wall, the opening device having hollow perforator mechanism that is adapted to perforate the closure wall of the reservoir, the hollow perforator mechanism being connected to an expulsion channel so as to transport the powder towards a dispenser orifice of the inhaler. The opening device including includes at least one air channel connected to the expulsion channel, such that during inhalation, an air flow passing through said the at least one air channel mixes, in the expulsion channel, with the air and powder flow leaving the reservoir through the hollow perforator mechanism. The air channel is formed by a through hole made in a wall of the perforator mechanism, the through hole being oriented substantially parallel to the expulsion channel.08-05-2010
20100236550DRY-POWDER MEDICAMENT - An inhalable dry powder medicament is provided. The medicament, which provides improved fine particle fraction, may be prepared by (i) fractionating a particulate active ingredient based on aerodynamic particle size, (ii) recovering at least one fraction of the particulate active ingredient and (iii) combining the recovered fraction with a carrier to provide the inhalable dry powder medicament.09-23-2010
20100275917POWDER INHALER - The present invention relates to a method, a device, and a control program for the fluid-tight sealing of capsules containing medicaments, wherein the capsules consist of at least one capsule body and a capsule cap which are set one into the other telescopically and provided with a tight band in the abutment region on the exterior side of the capsule, wherein the capsule components are filled with gas which has a changed temperature and/or a changed pressure in relation to the environment, and wherein a reduction of the difference in pressure in the capsule occurs via gaps between capsule body and capsule cap after the capsule components have been placed one inside the other. The capsules produced via the method according to the invention are disposable capsules and preferably contain a single dose of an orally administered pharmaceutical formulation in the form of a powder or a liquid.11-04-2010
20100242959DELIVERY OF GASES TO THE NASAL AIRWAY - A delivery device for providing therapeutic gas to the nasal airway of a subject, the delivery device comprising: a nosepiece (09-30-2010
20100242960Improvements in and Relating to Metered Dose Inhalers - An inhaler for dispensing a dose of an active agent to the respiratory tract of a patient, which inhaler comprises a housing defined by an upper part and a lower part and a mouthpiece which is attached or is adapted to be attached to said housing; wherein said housing includes storage means for storing an active agent and an airway for delivering said dose from the storage means to the mouthpiece in a stream of air or other gas for administration to a patient, characterised in that said upper part and said lower part of the housing are joined together in a substantially airtight fashion by means of a mechanical fixing, such that a gas flow rate of no more than about 45 litres/minute, preferably no more than about 40 litres/minutes, is required in order to propel a dose of said active agent from the reservoir to the mouthpiece for administration to the patient.09-30-2010
20100139654INHALER - An inhaler for delivering a powdered inhalation formulation from a blister strip having a plurality of blister pockets. The used part of the blister strip with emptied blister pockets is coiled by a clock spring or pushed into a helical channel. This results in a simple construction, in which the used blister strip is kept separate from the part that has not yet been used.06-10-2010
20100186740COATING METHODS, SYSTEMS AND RELATED ARTICLES - Medical articles with coatings are disclosed herein, as well as methods and systems for depositing these coatings onto medical articles. Surfaces of such articles may be coated. The coating(s) may serve as lubricants for reducing stiction between such surfaces or between a coated surface and another surface.07-29-2010
20100059049Dry-Powder Inhaler - The invention provides a dry-powder inhaler device 03-11-2010
20110056492EFFECTIVE DELIVERY OF NANOPARTICLES AND MICROMETER-SIZED PHARMACEUTICAL AEROSOLS TO THE LUNG THROUGH ENHANCED CONDENSATIONAL GROWTH - Methods and devices for inhalation therapy to deliver and embed (deposit) particles less than about 1 μm in diameter in the lung. High humidity treatment of the lungs causes condensational growth in particle size upon entering the lungs. Increased particle size is conducive to particle embedment (deposition) in deep lung tissue or at a specific targeted lung region.03-10-2011
20100000529MANIFOLD FOR USE IN MEDICAMENT DISPENSER - There is provided a manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack. The manifold comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit. The chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof in the airflow from the chamber inlet to said chamber outlet. The manifold is arranged such as to delay the emptying of the medicament powder from the blister pocket.01-07-2010
20100000528MANIFOLD FOR USE IN MEDICAMENT DISPENSER - There is provided a manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack. The manifold comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit. The chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof in the airflow from the chamber inlet to said chamber outlet. The chamber is arranged to promote break up of said entrained medicament powder by exposing the entrained medicament powder to one or more regions of differential force during its transport through the chamber.01-07-2010
20110126830DELIVERY DEVICES - A delivery device for delivering a metered amount of substance, the delivery device comprising: a mouthpiece (06-02-2011
20100192948Medicament Inhalers - This invention relates to improvements in or relating to medicament inhalers. In particular, the invention relates to a device for releasable attachment to a medicament inhaler, which monitors patient usage of the medicament inhaler. The invention may be particularly suitable for use with medicament inhalers used for the treatment of respiratory diseases.08-05-2010
20090114220Medicament dispensing device, medicament magazine therefor and method of removing a medicament from a medicament chamber - The invention relates to a medicament dispensing device, particularly a multi-dose powder inhaler, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine as depicted in exemplary FIG. 05-07-2009
20090107495DEVICE FOR INHALATION OF MEDICINE - An object of the present invention is to provide an inhalation device by which nano-sized particles of a medicine are able to be stably present without aggregation even in air or the like where no dispersing solvent is present. A device for inhalation of medicine according to the present invention for solving such a problem is that where medicine particles in a nano- to micron-size are adhered to a matrix comprising a nano fiber to such an extent that the particles are detached by inspiration permeating through the matrix.04-30-2009
20100300439NASAL DELIVERY DEVICES - A nasal delivery device for and method of delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a body assembly (12-02-2010
20100300441Metering Device for the Inhalation of a Pulverulent Substance - A dosing device can be activated by a vacuum air stream of a user for the inhalation of a powder substance, particularly medicine, which is arranged in a supply chamber and which can be brought out of the same into an open emptying-ready position by a dosing chamber of a dosing rod when the mouthpiece-closure cap is removed. In particular, in order to improve dispensing, the provision of two air paths, of which one serves to open and empty the dosing chamber, and/or the second air path penetrates directly into a ring chamber in order to mix with the air flow containing the substance.12-02-2010
20090188497MEDICAL PRODUCT CONTAINING TIOTROPIUM - The invention discloses a medical product that may be used in a treatment of respiratory disorders.07-30-2009
20100175698CAPSULE - A capsule for a powder has a body which is provided with an internal chamber to hold the powder and first and second openings to an exterior environment. The body is adapted to be displaced from a filling state, in which the first and second openings are placed in fluid communication with one another through the internal chamber thereby enabling an airflow to be created through the body from the second opening to the first opening which is able to entrain powder in the exterior environment into the internal chamber for filling thereof, to a sealing state in which the internal chamber is sealed from the exterior environment so as to retain the powder held therein.07-15-2010
20110083667DISPENSER AND METHOD FOR ENTRAINING POWDER IN AN AIRFLOW 537 - The invention relates to a method for entraining in an airflow a medicament powder contained in a cavity having a cavity opening. Large airflow vortices are provided, for instance, by means of an obstacle in a flow passage. The airflow with large vortices is arranged to by-pass the cavity opening, thereby generating an eddy in the cavity which contributes to entraining the powder in said airflow. The invention also relates to a medical dispenser, for instance an inhaler, in which said method may be performed.04-14-2011
20100258119MEDICINAL INHALATION DEVICES AND COMPONENTS THEREOF - A medicinal inhalation device having applied to surface thereof a composition comprising a monofunctional polyfluoropolyether silane and a non-fluorinated cross-linking agent.10-14-2010
20100175697FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device comprising a body (07-15-2010
20090217928Powder aerosolization apparatus and method - An aerosolization device comprises a chamber adapted to contain a powder pharmaceutical formulation, a lid at least partially covering the chamber, at least one piercing element forcible through the lid to provide access to the powder pharmaceutical formulation, and a shapeable surface extending from the chamber, the shapeable surface being adapted to undergo a shape change to form a conduit. The powder pharmaceutical formulation may be extracted from the chamber by a user inhaling through the conduit. In another version, the lid is removable from the chamber without the need for a piercing element.09-03-2009
20100031956FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device including at least one individual reservoir (02-11-2010
20100037894MANIFOLD FOR USE IN MEDICAMENT DISPENSER - There is provided a manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack. The manifold comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit. The chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof in the airflow from the chamber inlet to said chamber outlet. The chimney is arranged to create turbulence in the airflow at the open blister pocket.02-18-2010
20100059050MOUTHPIECE FOR AN INHALER - A mouthpiece for an inhaler for administering a drug in the form of substances, substance formulations or substance mixtures that can be inhaled comprises an inhalation channel (03-11-2010
20100065050MEDICAMENT DISPENSING DEVICE WITH A MULTIMATERIAL DIAPHRAGM BOUNDING A PNEUMATIC FORCE CHAMBER - A metered dose inhaler for use with a pressurized aerosol container which is preferably breath-actuated. A preload is applied to the internal aerosol valve by an amount sufficient to result in a dose release, but this is prevented by the application of a pneumatic resisting force. The inhaler comprises a release device which, upon actuation, releases the resisting force and allows the preload to actuate the aerosol valve. A metered dose of medicament is then released for inhalation by the patient. The pneumatic resisting force is established by a negative pressure region defined in part by a diaphragm. The diaphragm includes a central disk of a first, relatively high stiffness material and a peripheral ring, coupled by a flexure of a second, relatively low stiffness material.03-18-2010
20100059052SHEET DRIVER FOR USE IN A DRUG DISPENSER - The present invention relates to a sheet driver for use in a drug dispenser including a drug carrier (03-11-2010
20100065049DEVICE FOR DELIVERING MEDICAMENT - The present invention relates to a device for delivery of medicament comprising a main housing; a container arranged in said housing and arranged to be connected to a medicament delivery member, wherein said container includes at least two chambers and at least one longitudinally movable plunger and wherein at least one chamber contains a medicament agent; a pre-treating arrangement acting on said container; drive force means acting on a longitudinally movable plunger rod capable of exerting a force on said container; and activating delivery means acting a said drive force means for delivering medicament via said medicament delivery member characterised in that said pre-treating arrangement comprises clickable means for manually and delay intermittently mixing said medicament agent and for manually priming said container03-18-2010
20100065048DRY POWDER INHALER DEVICES - A DPI device comprising a dispensing chamber for receiving a discrete dose of medicament-containing powder and means for delivering said dose from the dispensing chamber to a patient in an air-flow that passes from the chamber to the patient via a mouth-piece along a first air passage that comprises de-agglomerating means, the device additionally comprises a second air passage in fluid communication with the dispensing chamber and the mouth-piece and which by-passes the de-agglomerating means and which is located such that it receives a portion of said air-flow that is free, or substantially free, of powder.03-18-2010
20110067696POWDER INHALER - An object of the present invention is to provide a powder inhaler that does not require shaking, and that therefore can be operated in an efficient manner.03-24-2011
20110061653DISPENSER FOR PULVERULENT SUBSTANCES CONTAINED IN A SEPARATE PACK - The invention relates to a dispenser for pulverulent compounds contained in a separate pack, in particular compounds contained in a blister pack, wherein the pack has a container part and a tear-off container cover, wherein, furthermore, an air flow aspirated after removal of the container cover from the container part is at least partially aspirated through the container part. The container cover projects out of a tear-off opening of the dispenser for actuating purposes. The dispenser of the type in question is improved in a structurally simple manner such that functionally reliable handling is provided over the course of the inhaling operation. The air flow is aspirated laterally into the dispenser with respect to a tear-off direction of the container cover, and that the container cover closes the tear-off opening.03-17-2011
20110061652BLISTER FOR INHALERS - The invention relates to a blister for charging an inhaler with a pharmaceutical preparation, characterised in that the blister is at least partially manufactured from a dehydrating plastics material. The invention also relates to blisters according to the invention which are filled with a pharmaceutical preparation.03-17-2011
20110048419DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser device comprising: a body (03-03-2011
20100263667MEDICINAL INHALATION DEVICES AND COMPONENTS THEREOF - A medicinal inhalation device having applied to a surface thereof a composition comprising a multifunctional polyfluoropolyether silane.10-21-2010
20100258118INHALER DEVICES AND BESPOKE PHARMACEUTICAL COMPOSITIONS - The present invention relates to inhaler devices and bespoke pharmaceutical dry powder composition to be dispensed using such inhaler devices for pulmonary administration. In particular, the present invention relates to the provision of passive inhaler devices and dry powder compositions which are specifically formulated and prepared to be efficiently dispensed by such devices to reproducibly achieve a high delivered dose of the pharmaceutically active agent.10-14-2010
20100000531DRY POWDER INHALERS - A dry powder inhaler comprises two parts (01-07-2010
20110146678PROCESS FOR IMPROVING CRYSTALLINITY - This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.06-23-2011
20120199122DELIVERY SYSTEM - There is described a medicament delivery device which comprises a medicament reservoir, a medicament delivery passage and a metering member adapted to transfer a measured dose of medicament from the medicament reservoir to the delivery passage characterized in that the device is provided with a moisture proof barrier. The medicament delivery device is especially suited for use as an inhaler. There is therefore also described an inhaler which provides improved airflow for the dispersion of medicament, and a method of treating patients suffering from a respiratory disorder.08-09-2012
20090308388INHALER - A dry powder inhaler (12-17-2009
20090000619Powder Inhaler, System for Opening and Emptying Capsules - The invention consists of a system for opening and emptying capsules in a powder inhaler for administering medications The inhaler according to the invention has a chamber with a system for opening the medication capsule in which the process of opening and emptying the medication capsule takes place as well as an aerodynamic chamber in which the medication particles are separated from the carrier capsules. The aerodynamic chamber may also be used as a mouthpiece.01-01-2009
20090126732DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION - The present invention provides a novel dry powder inhalation system suitable for transpulmonary administration. The dry powder inhalation system of the invention characterized by using a combination of: 05-21-2009
20080314384Dry Powder Inhalers - A dry powder inhaler comprises a main airflow path including a cyclone chamber (12-25-2008
20080314383Dry Powder Inhalation Apparatus - The invention relates to dry powder inhalation apparatus usually operable by breath of a user which provides for controlled and smooth transfer of medicament during multiple actuations by a user. A mechanism of the apparatus for achieving this controlled and smooth transfer includes a device (12-25-2008
20120199121INHALERS - A dry powder inhaler incorporates a cyclone chamber (08-09-2012
20090178676SIMPLE INHALER - A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body and a cartridge with one or more compartments each containing one dose of a drug. The compartment has holes to admit air and holes to deliver powder, which, in use, communicate with an inhalation channel in the inhaler body. To prevent the powder from leaking through the compartment holes before use, the air admission holes are of reduced dimension, thereby blocking or hindering powder exit under the force of gravity. When the cartridge is inserted inside the inhaler body, all its holes can be blocked. By sliding the cartridge in relation to the body until the inhalation position is reached, the holes come into in fluid communication with one another and with the inhalation channel, thereby allowing a flow of air to disperse and entrain the dose through the mouthpiece. Five embodiments are disclosed.07-16-2009
20100300442Dispensing Device - A device for dispensing individual doses of powder from respective pockets of a disc-shaped carrier by outwardly rupturing a lidding foil by means of pressure on an opposite side surface, the device providing individual respective deaggregation flow paths for each pocket, split airstreams allowing improved entrainment of powder, a cam mechanism for outwardly rupturing the pockets, an indexing mechanism linked to the cam mechanism and a dose counter.12-02-2010
20110253141METHODS OF OPERATING DRY POWDER INHALERS HAVING SPIRAL TRAVEL PATHS WITH MICROCARTRIDGES OF DRY POWDER - Dry powder inhalers include: (a) a first generally planar spiral travel path in an inhaler body, wherein the first spiral travel path has a plurality of adjacent curvilinear channels forming lanes with upstanding sidewalls, including an inner lane and an outer lane; and (b) a plurality of discrete sealed microcartridges with substantially rigid bodies disposed in the first travel path, each comprising a pre-metered (typically dose) amount of dry powder, the microcartridges being configured to slidably advance along the first travel path toward an inhalation chamber that merges into an inhalation output port. In operation, at least one microcartridge is held in the inhalation chamber to release the dry powder therein during inhalation.10-20-2011
20110253140FORMULATIONS CONTAINING LARGE-SIZE CARRIER PARTICLES FOR DRY POWDER INHALATION AEROSOLS - A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 μm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.10-20-2011
20110162648INHALER MECHANISMS WITH RADIALLY BIASED PIERCERS AND RELATED METHODS - Inhalers with an inhaler housing having a dose container disk having inner and outer perimeters mounted in the housing. The dose container disk has a plurality of circumferentially spaced apart dose containers with dry powder therein. The inhalers also include a piercer carriage with a piercer mounted in the inhaler. The piercer carriage is in communication with a resilient member that radially biases the piercer carriage to radially travel to align the piercer with an underlying or overlying dose container.07-07-2011
20100319694Delivery of powdered drug via inhalation - Described herein are hand-held inhalation devices for use with tidal breathing that deliver powdered active agents to the respiratory system. The inhalation devices deliver a unit dose of the powdered active agent over a series of inhalations during tidal breathing. Methods for using the inhalation devices and kits for inhalation delivery of various active agents are also described.12-23-2010
20110108030AIRFLOW ADAPTOR FOR A BREATH-ACTUATED DRY POWDER INHALER - An airflow adaptor for a breath-actuated dry powder inhaler. The airflow adaptor includes a conduit having a proximal end and a distal end, wherein the proximal end allows fluid communication from a deagglomerator outlet port to the distal end of the conduit, and wherein the airflow adaptor further includes provisions for allowing air to flow from a proximal end of the adaptor to a distal end of the adaptor independently of the airflow in the conduit when a breath induced low pressure is applied to the distal end of the airflow adaptor.05-12-2011
20120031403DRY POWDER FORMULATION COMPRISING A PHOSPHODIESTERASE INHIBITOR - Pharmaceutical formulations in the form of inhalable dry powder comprising particles of a phosphodiesterase-4 inhibitor as active ingredient are useful for the prevention and/or treatment of respiratory diseases, such as asthma and COPD.02-09-2012
20110132357COMPOSITIONS, METHODS & SYSTEMS FOR RESPIRATORY DELIVERY OF TWO OR MORE ACTIVE AGENTS - Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.06-09-2011
20100319693FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device including a body (12-23-2010
20110023876COMPOSITIONS FOR PULMONARY DELIVERY OF LONG-ACTING MUSCARINIC ANTAGONISTS AND ASSOCIATED METHODS AND SYSTEMS - Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting β02-03-2011
20100083962DISPENSER FOR PULVERULENT SUBSTANCES - The invention relates to a dispenser (04-08-2010
20120145149VENTILATOR CIRCUIT AND METHOD FOR THE USE THEREOF - A ventilator circuit for use in administering medication to a patient includes a housing, a one-way inhalation valve and a one-way exhalation valve. A metered does inhaler receptacle is in fluid flow communication with an interior space of the housing holding chamber. An exhaust conduit communicates between input and output passageways disposed on opposite sides of the interior space.06-14-2012
20110174306Dry Powder Inhalers with Multi-Facet Surface Deagglomeration Chambers and Related Devices and Methods - Dry powder inhalers and methods are provided that facilitate deagglomeration of powdered medicament during inspiration. A dry powder inhaler includes a dry powder medicament container assembly, and an elongated dry powder delivery tube having an inlet at one end that communicates with a dose container, and an outlet or inhalation port that extends from the inhaler housing at an opposite end. The delivery tube includes one or more apertures adjacent the inlet that cause cyclonic or turbulent airflow through the delivery tube. The inner surface of the delivery tube has a polygonal configuration and the cyclonic air stream bounces off the polygonal inner surface numerous times as the air stream flows through the delivery tube. Another dry powder inhaler includes a deagglomeration chamber with a polygonal inner surface. An air stream containing dry powder medicament is directed into the deagglomeration chamber and impacts the polygonal inner surface numerous times.07-21-2011
20090308389FLUID-PRODUCT DISPENSING DEVICE - An inhaler comprising: at least one cover element (12-17-2009
20090308386Device for Delivering Medicament - The present invention relates to a device for the delivery of predetermined doses of liquid medicament to a patient, which medicament is intended to be inhaled by the patient or intended to be injected into the body of the patient. The device is adapted to be in a medicament delivery state and in a medicament non-delivery state. When the device is in a medicament delivery state, said device is adapted to drive a piston into a cartridge containing the liquid medicament to be delivered, with a predetermined force value. The device is designed and arranged to ensure that the predetermined dose of medicament expelled from the cartridge has a high degree of accuracy and to show the user in a simple manner how much medicament is remaining in the cartridge after a dose or several doses has/have been expelled and at the same time offering a shorter device, which is more convenient for the user when he/she has to carry it with him/her.12-17-2009
20090277446INHALER - Disclosed is an inhaler, especially a powder inhaler, for administering a medicament in the form of inhalable substances, substance formulations, or substance mixtures. Said inhaler comprises a housing that is provided with a chamber (11-12-2009
20100024815PISTON DOSING PUMP - A preferably pulverulent formulation to be dosed is received in a dosing chamber having a partly gas-permeable wall. The introduction and discharge of the formulation is achieved by means of a pumping device that alternately generates a negative pressure and an excess pressure in the dosing chamber. The dosing chamber can also be displaced between a receiving position and a discharge position by means of a piston, the piston controlling the negative and excess pressure in the dosing chamber. Furthermore, the size of the dosing chamber is adjustable.02-04-2010
20100018527FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device comprising: a body (01-28-2010
20120145150DRY POWDER INHALER - A dry powder inhaler includes a chamber holding an actuator to which a powdered medicament is adhered. Air is drawn into the chamber through an inlet flow channel and exits through an outlet flow channel. The actuator oscillates in response to the air flow, dislodging powdered medicament to be entrained in the air flow and delivered to the patient. A retaining member prevents the actuator from exiting the chamber. Thus, the medicament may be delivered to the patient without the use of carrier particles.06-14-2012
20110005523Pharmaceutical Polypeptide Dry Powder Aerosol Formulation and Method of Preparation - Dispersible powder compositions suitable for inhalation are disclosed, the compositions including a human interleukin mutein (mhIL-4).01-13-2011
20090188496INHALABLE TIOTROPIUM AND CONTAINER THEREFOR - A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.07-30-2009
20120037157INHALER - An inhaler (02-16-2012
20080276935TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS - Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and an additive.11-13-2008
20120097160AGGLOMERATE FORMULATIONS INCLUDING ACTIVE PHARMACEUTICAL AGENTS WITH TARGETED PARTICLE SIZES - Various embodiments of the present invention provide for an agglomerate comprising at least one active pharmaceutical agent and at least one excipient; wherein at least about ninety percent of the at least one active pharmaceutical agent have a particle size of less than about 2 μm.04-26-2012
20080289630Pre-metered dry powder inhaler for moisture-sensitive medicaments - The invention discloses a pre-metered dry powder inhaler for use in treatment of respiratory disorders. The inhaler comprises a foil cutter arranged for opening a dry, moisture-tight seal formed by a dose container with tiotropium particles and a seal foil fixed to the container. The tiotropium-containing dose protected from moisture ingress by the moisture-tight barrier seal is loaded in the container using volumetric or electric field dose forming techniques.11-27-2008
20100154794Inhaler Flow Channel - The present invention provides an inhaler, which separates the drug aerosolization process and the drug delivery process within the inhaler, and controls the inhalation air flow profile in a way, such that transportation of the drug in the inhaler flow channel is enveloped in a laminar air stream presented to the air tract of the user, thereby eliminating drug deposition on the inhaler inside walls. The inhaler invention therefore provides advantages over other inhalers, especially, when a repeatable emitted dose is important and generally, where contamination and hygiene in the flow channel is an issue as is the case with multi-dose inhalers.06-24-2010
20100012119FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device comprising a body (01-21-2010
20080283055DISPENSING DEVICE - A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert by a pressurizing gas via a connecting element that is moveable relative to the inserts for individually supplying pressurized gas to a respective one of the receptacles. A mechanism is provided for preventing a back stroke of the connecting element during supplying of the pressurizing gas and dispensing of the formulation.11-20-2008
20100269825INHALATION PARTICLES COMPRISING A SALT OF 8-HYDROXY-2-[[(1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL]AMINO] ETHYL]-2(1H)-QUINOLINONE AND A CORTICOSTEROID - Crystalline particles wherein each particle comprises a combination of a pharmaceutically acceptable salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone (carmoterol), and a corticosteroid in a pre-determined and constant ratio are effective for the prevention and treatment of inflammatory or obstructive airways diseases.10-28-2010
20120111324Dry Powder Drug Delivery Formulations, Methods of Use, and Devices Therefore - The present disclosure relates to systems, methods, and formulations for the pulmonary administration of one or more therapeutic agents, in dry powder form, in a single, large dose quantity. These formulations, methods, and systems are useful in the treatment of patients suffering from toxic or harmful gas exposure, such as nerve gas exposure, as well as in the treatment of patients suffering from diseases of the pulmonary system, including tuberculosis, cystic fibrosis, and chronic obstructive pulmonary disease (COPD).05-10-2012
20120152245DRY POWDER INHALER DOSE COUNTERS - Dry powder inhaler dose counters capable of making a display move swiftly between digits, in contrast to the progressive movement that occurs in simple gearing mechanisms.06-21-2012
20120103332Powder Delivery Devices and Methods of Using the Same - A powder delivery device (05-03-2012
20100095962Dose indicating device - An indicating device suitable for indicating the number of metered dosages that have been dispensed from or remain in a container includes a base member adapted to be mounted to the container and a cap member moveably connected to the base member. The cap member is moveable relative to the base member along an axial path. A shaft is non-rotatably mounted to one of the cap member and the base member and defines an axis. An indicator member is rotatably mounted on the shaft and is rotatable in at least a first direction. One of the shaft and the indicator member has a helical groove while the other of the shaft and the indicator member has a follower disposed in the groove. The indicator member is moveable relative to the shaft along the axis as the indicator member is rotated in the first direction. In another embodiment, the indicating device includes first, second and third indicator members. In yet another embodiment, the indicating device includes a housing having a longitudinally extending cavity shaped to receive the container and an indicator member disposed in the cavity and having a longitudinally extending wall shaped to surround at least a portion of the container. The indicator member is rotatably mounted within the housing and is rotatable relative thereto about a longitudinal axis. The indicator member includes a driven gear. A drive gear is disposed in the housing and includes a drive portion selectively engaged with the driven gear. An actuator is adapted to move with the container and is selectively engaged with the drive gear.04-22-2010
20100095963PHARMACEUTICAL COMPOSITIONS - Disclosed are aerosolized formulations for the treatment of asthma that contain mometasone furoate and processes for preparing the same.04-22-2010
20120160241UPGRADED INHALATOR FOR POWDER PREPARATIONS - An upgraded inhalator for powder preparations comprises a main body having an inhalation channel, an external opening accessible by a user, and a tank adapted to receive a dose of powder preparation. The tank is opened to establish communication with the inhalation channel. At least one protuberance protrudes or extends towards the inside of the inhalation channel. Each protuberance defines substantially concave impact surface and is arranged on the opposite side to the external opening. The impact surface of each protuberance intercepts the powder preparation during its crossing of the inhalation channel towards the external opening.06-28-2012
20100300440Dry powder inhaler system - The present invention relates to a pharmaceutical composition for inhalation, consisting in a combination of (A) a dry powder formulation containing a micronized active ingredient, alone or mixed with an inactive ingredient, said powder being filled in a hydroxypropylmethylcellulose (HPMC) capsule and (B) a single dose dry powder inhaler device especially adapted to said capsule to provide a high respiratory dose of said active ingredient when said drug is inhaled by the mouth through said device. Said device being characterized in that he is equipped with piercing is needles or pins (in order to pierce the capsule) of diameter of not less than 0.8 mm preferably not less than 1 mm.12-02-2010
20110114092Dry Powder for Inhalation - The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. On of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.05-19-2011
20120125330INHALATION DEVICE AND METHOD OF DISPENSING MEDICAMENT - The present invention relates to an inhaler, comprising a base having at least one air-tight, foil-sealed cavity containing medicament. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. The invention also relates to a method of dispensing a medicament from a sealed cavity inside an inhaler.05-24-2012
20120125331DRY POWDER INHALER WITH AEROELASTIC DISPERSION MECHANISM - A dry powder inhaler for delivering medicament to a patient includes a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and an aeroelastic element in the chamber and associated with a dose of powdered medicament. A tensioning assembly is configured to apply a first amount of tension to the aeroelastic element such that the aeroelastic element is capable of vibrating in response to airflow through the chamber so as to aerosolize the dose of powdered medicament.05-24-2012
20120247463BI-FUNCTIONAL INHALING DEVICE - The bi-functional inhaling device has an elliptic shape in the frontal, lateral and transversal plane and includes a lower part and an upper part, a lower cap being located at the lower part to accommodate inside a cartridge made up of a lower cap, a strip of absorbent material, a body and an upper cap of the cartridge. An adapter for oral inhaling is mounted over the upper cap of the cartridge, the adapter being covered with a protection cap. An adapter for nasal inhaling is mounted over the upper cap of the cartridge. A membrane is secured on the base surface of the upper cap of the cartridge, the membrane having the role of a one-way valve. Natural salt crystals are introduced inside the cartridge, in the space created between the lower cap, the upper cap and the body of the cartridge.10-04-2012
20100288277INHALERS - A dry powder inhaler comprises at least one medicament reservoir and a closure member engaged with the reservoir so as to close an opening therein. A surface of the reservoir adjacent the opening and a surface of the closure member are in abutment, either directly or via a seal member interposed between the reservoir and the closure member. At least one abutting surface is formed with a projection that increases the contact pressure between said surfaces, thereby improving the seal between them and reducing the potential for ingress of moisture between said surfaces into the reservoir.11-18-2010
20100288276COMPOSITIONS FOR TREATING PARKINSON'S DISEASE - The present invention relates to improved treatment of diseases and disorders of the central nervous system by administration of apomorphine. In particular, the administration is via pulmonary inhalation. The invention provides the means for improving the treatment of a number of conditions, including Parkinson's Disease.11-18-2010
20100288275NASAL ADMINISTRATION - A delivery device for and method of delivering a powdered substance, in particular a triptan, such as sumatriptan, to the posterior region of a nasal cavity of a subject, in particular for the treatment of headaches, for example, cluster headaches and migraine, and neuropathic pain, the delivery device comprising: a nosepiece (11-18-2010
20120211007INHALER FOR THE ADMINISTRATION OF AN ANTICHOLINERGIC - An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1, √{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 μm, and a method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 08-23-2012
20120132204UNIT DOSE DRY POWDER INHALER - An inhaler includes a first body member and a second body member fit closely together to form an inhaler body, and an outlet. The first body member has a medicament chamber containing a unit dose of powdered medicament. A seal such as a foil strip seals the medicament chamber and extends outwardly of the inhaler body. In use, one end of the seal can be grasped by a user and withdrawn, fully or partially, from the inhaler body, to release the powdered medicament from the medicament chamber. The second body member includes a medicament collection well in which the medicament is collected upon its release from the medicament chamber. The medicament collection well forms part of an airway connecting into the outlet. In use, air can be drawn by inhalation at the outlet to entrain the powder medicament in the collection well for inhalation by a user.05-31-2012
20090188495PRE-METERED DRY POWDER INHALER FOR MOISTURE-SENSITIVE MEDICAMENTS - The invention discloses a pre-metered dry powder inhaler for use in treatment of respiratory disorders. The inhaler comprises a foil cutter arranged for opening a dry, moisture-tight seal formed by a dose container with tiotropium particles and a seal foil fixed to the container. The tiotropium-containing dose protected from moisture ingress by the moisture-tight barrier seal is loaded in the container using volumetric or electric field dose forming techniques.07-30-2009
20120132203DRY POWDER INHALERS - Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, the compartment being configured such that said preloaded doses are sealed within said compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system, wherein the moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier, said sealing system being in sealing configuration prior to an advancement of the carrier, relaxed upon an advancement of the carrier and returned to its sealing configuration at the latest after release of the powder associated with said area of the carrier.05-31-2012
20100192949Inhaler - An inhalation device comprising a base having a slot for insertion of a single blister containing a dose of medicament to be inhaled into the base is disclosed. The inhaler has a mouthpiece pivotally mounted to the base which carries a blister piercing element operable to pierce a blister received in said slot when the mouthpiece is pivoted relative to the base. When a user inhales on the mouthpiece, the dose is entrained in an airflow and flows out of the blister through the mouthpiece and into the user's airway.08-05-2010
20120247466Drug Delivery Device - The present invention discloses a device useful for facilitating delivery of drugs or medicaments to the respiratory system of a user. The device comprising a mechanism for interrupting the airflow during inhalation or exhalation performed by the user through the device by generating pressure pulses within the respiratory system of the user, such that the delivery of the drugs to the user is facilitated; the pressure pulses are selected from the group consisting of: inspiratory Negative Pressure (NP) pulses, inspiratory Positive Pressure (PP) pulses, expiratory Negative Pressure (NP) pulses, expiratory Positive Pressure (PP) pulses into the respiratory system, and any combination thereof.10-04-2012
20120247465MEDICAMENT DISPENSING DEVICE, MEDICAMENT MAGAZINE THEREFOR AND METHOD OF REMOVING A MEDICAMENT FROM A MEDICAMENT CHAMBER - A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (10-04-2012
20100051027Entraining Powder In An Airflow - A device for inhalation of at least one air stream carrying a dose of medicament powder. The device comprises a powder-containing cavity which opens into a flow passage. The flow passage is arranged to direct an inhalation air flow across the cavity opening. A circulating flow is thereby induced in the cavity by the phenomenon of shear driven cavity flow. Powder is entrained in the circulating flow and deaggregated before exiting the cavity and becoming entrained in the flow of air along the flow passage.03-04-2010
20090308387Acoustic Inhaler Flow Measurement - A dry powder or aerosol inhaler having attached thereto, in a detachable manner, a sound/vibration sensor adapted to sense sound/vibration in the interval of 100-3000 Hz and there from derive a parameter of a flow in a flow path of the inhaler. The sensor does not interfere with the flow path of the inhaler.12-17-2009
20090114219IMPROVEMENTS IN OR RELATING TO INHALERS - An inhaler device (05-07-2009
20090056710Inhaler for Powdery Substances - The invention relates to an inhalator (03-05-2009
20100012118Medicament dosage for inhaler - The manual filling of vaporizable substances into the filling chamber of an inhaler by the user is suitable, in particular, for the requirements of a medical application only in limited circumstances. As a rule, there is the risk of an incorrect dosage. Moreover, many patients are not at all capable of carrying out such a difficult task owing to their motor skills ailments or other conditions that render them disabled. Medical application therefore requires an economical form that has already been pre-dosed with the desired substance (medicament) by the pharmacist or the pharmaceutical company and that is a standardized single-use component. A dosage pad that has already been pre-dosed by the manufacturer ensures that the proper amount of medication is used. In particular, a dosage pad containing a medicament that is vaporizable by heat in an inhaler and that is effectual upon inhalation avoids the problems associated attempting to fill an inhaler manually with the correct dosage.01-21-2010
20120255549COUNTER FOR A FLUID OR POWDER DISPENSER DEVICE - A dose counter, the counter having a base body, with a rotary counter element assembled in the base body on a pin forming the axis of rotation. The rotary counter element co-operating with an actuator member adapted to cause the rotary counter element to turn each time the actuator member is actuated. The actuator member including a fastener for fastening to the base body (10-11-2012
20120298107DISPENSING DEVICE - A device for dispensing individual doses of powder from respective pockets of a disc-shaped carrier by outwardly rupturing a lidding foil by means of pressure on an opposite side surface, the device providing individual respective deaggregation flow paths for each pocket, split airstreams allowing improved entrainment of powder, a cam mechanism for outwardly rupturing the pockets, an indexing mechanism linked to the cam mechanism and a dose counter.11-29-2012
20120260916DRY-POWDER INHALER - An inhaler for delivering dry-powder medicament to a patient from an open blister pocket of a blister pack. The inhaler includes a housing for enclosing used and unused portions of the blister pack together with a medicament dispensing mechanism. The inhaler also includes a manifold through which air can be drawn in use of the inhaler, the manifold including an air inlet for receiving external air, at least one medicament aperture for communicating with an opened pocket of the blister pack to enable entrainment of the medicament by the air drawn through the manifold, and an air outlet for delivery of the entrained medicament to the patient. The medicament dispensing mechanism includes a guide surface for guiding the cover sheet of the unused portion of the blister pack. The manifold and the guide surface are defined by separate components of the inhaler.10-18-2012
20100326439INHALER - An inhaler ejects liquid droplets or powder granules into an airflow duct 12-30-2010
20100326438DRY POWDER INHALER - An inhaler is proposed which comprises a chamber containing powder. The powder can be discharged by an airflow. The airflow through the chamber is regulated by means of a valve at a desired or required minimum flow rate. The flow rate through the chamber is kept essentially constant.12-30-2010
20100326437INHALABLE MEDICAMENT - An inhalable medicament is provided, in particular a new solid-state form of tiotropium bromide. The medicament can be in the form of solid amorphous particles containing an intimate admixture of tiotropium bromide together with a pharmaceutically acceptable co-solid having a glass transition temperature of at least −50° C., such as a sugar and/or sugar alcohol.12-30-2010
20110120467POWDER INHALATION DEVICE - A powder inhaler comprising: a body (05-26-2011
20110120466POWDER INHALATION DEVICE - A powder inhaler comprising: a body (05-26-2011
20110120465Inhaler and sieve for an inhaler - The invention relates to an inhaler (05-26-2011
20110120464INHALERS - A dry powder inhaler comprises at least one medicament reservoir containing a bulk quantity of a powdered medicament, and a metering mechanism by which unit doses of said medicament can be dispensed from the medicament reservoir for inhalation by a user of the inhaler. The at least one medicament reservoir is formed in polyester material. Penetration of moisture through the walls of the medicament reservoir is considerably reduced.05-26-2011
20110120463DRY POWDER INHALER - The invention relates to a dry powder inhaler, having a base housing, having a capsule receptacle for a capsule containing dry powder, having at least one needle- or blade-like opening means, movably arranged in relation to the base housing, for opening the capsule, and having a mouthpiece, through which the dry powder from an opened capsule can be inhaled. The invention is distinguished in that the opening means are fastened on the mouthpiece, and that the mouthpiece can be moved in respect to the base housing out of a normal position into an opening position which opens the capsule.05-26-2011
20120260917DRY POWDER INHALER - The present invention relates to an inhaler which is appropriate for delivery of medicament in dry powder form used in respiratory diseases, particularly in asthma and chronic obstructive pulmonary disease (COPD). In addition, the present invention relates to an inhaler which includes a blister package appropriate for carrying the medicament in dry powder form and used to realize an effective inhalation.10-18-2012
20110226244DRY POWDER INHALERS WITH ENDLESS STRIPS AND COOPERATING PIERCERS AND RELATED METHODS - Dry powder inhalers are described with an inhaler body defining an enclosed cavity space and at least one of (a) an endless strip having opposing primary surfaces, the strip comprising a plurality of spaced apart blisters or dose containers holding dry powder medicament. The inhaler also has an inhalation exit flow path in the inhaler body in communication with at least one blister or at least one dose container held by the strip in a dispensing position and a piercer configured to release dry powder medicament from the blister or dose container in the dispensing position.09-22-2011
20110226243DEVICE AND METHOD FOR DEAGGREGATING POWDER 854 - The present disclosure relates to a device for inhalation of at least one air stream carrying a dose of medicament powder. The device comprises a flow passage passing a powder-containing cavity. A part of said flow passage propagates along a generally flat surface region. The flat surface region comprises a cavity opening into said powder-containing cavity. The passing of an air stream along said flat surface region and outside said cavity generates an eddy in the cavity and the generated eddy contributes to deaggregation of the powder in said cavity and emptying of the powder from said cavity. Furthermore, the present disclosure relates to the use of a shear driven cavity principle on such a device and a method of releasing medicament powder.09-22-2011
20120080031RESPIRATORY SYSTEM FOR INDUCING THERAPEUTIC HYPOTHERMIA - The present invention provides a method and apparatus for controlling a patient's body temperature and in particular for inducing therapeutic hypothermia. Various embodiments of the system are described. The system includes: a source of breathing gas, which may be in the form of a compressed breathing gas mixture; a heat exchanger or other heating and/or cooling device; and a breathing interface, such as a breathing mask or tracheal tube. Optionally, the system may include additional features, such as a mechanical respirator, a nebulizer for introducing medication into the breathing gas, a body temperature probe and a feedback controller. The system can use air or a specialized breathing gas mixture, such as He/O.sub.2 or SF/O.sub.2 to increase the heat transfer rate. In addition, the system may include an ice particle generator for introducing fine ice particles into the flow of breathing gas to further increase the heat transfer rate.04-05-2012
20110259328SIMPLE CAPSULE-BASED INHALER - A dry powder inhaler for pulmonary or nasal use, employing capsules containing a dose of powder for inhalation, comprising two operating components and an optional cover. Air is drawn by the patient via a mouthpiece or nosepiece which is in communication with the capsule and travels via air paths through the device and through the capsule thereby dispersing and entraining the dose of powder. The capsule is cut by cutting means located on one of the components, in a manner which eliminates or minimizes capsule debris and minimizes powder leakage during use. The inhaler body and capsule cutting blades comprise a single operating component and they may be manufactured in a single unitary step. The invention affords a very economical and simple device for the delivery of pulmonary medicines.10-27-2011
20100229860SYNTHETIC JET BASED MEDICAMENT DELIVERY METHOD AND APPARATUS - A dry powder inhaler consisting of first chamber having an orifice for holding a dry powder and a gas, and a second chamber for receiving a deaggregated form of the dry powder and for communicating the deaggregated dry powder to a user. A synthetic jet drives the dry powder from the first chamber to the second chamber.09-16-2010
20100229859POWDER FILLING PROCESSES - A method for filling a plurality of microdepressions in a major surface of a web with finely divided powder in which the web is fed continuously to and through a powder filling stage including a driven roller. At the powder filling stage, the powder, which is fed either onto the web upstream of the roller or to the roller of the powder filling stage, is filled into the microdepressions of the web using the driven roller, wherein said roller is rotating about an axis generally transverse to the direction of web, while the surface speed of the roller and the web speed are different and wherein the roller and web are positioned relative to one another, such that between the upper surface of the web and the outer surface of the roller there is a gap. A method of manufacturing an elongate carrier with microdepressions containing finely divided powder comprising steps filling a plurality of microdepressions in a major surface of a web as described, removing from upper surface of the web excess powder not filled within the microdepressions and remaining on areas of the surface between the depressions, and optionally slitting and/or cutting the web in width and/or length.09-16-2010
20120090607METER FOR A DEVICE FOR DISPENSING A FLUID OR POWDER PRODUCT - A dose counter having a base body (04-19-2012
20120090606 APPARATUS FOR THE AEROSOLIZATION OF LARGE VOLUMES OF DRY POWDER - The claimed subject matter relates to a device for dosing and aerosolization of aerosolizable material. The device comprises: a body with an aerosolization channel with a distal attachment portion connectable to a source of carrier gas which provides pressure pulses to the aerosolization channel; a proximal attachment portion for outputting aerosolized material and a reservoir for receiving aerosolizable material. The reservoir comprises walls and is connected in a gas-tight manner to the body and in fluid connection with the aerosolization channel. At least part of the walls of the device are self-exciting membranes that can be put into oscillation by the pressure pulses.04-19-2012
20100199986INHALER - An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets. The used part of the blister strip with empty blister pockets is wound onto a drum which is driven via a gear mechanism which is coupled to the drum via a spring. The spring allows for the different peripheral speeds of the wound-up part to be compensated.08-12-2010
20090250058Inhalation System and Delivery Device for the Administration of a Drug in the Form of Dry Powder - The administration of at least one drug in the form of dry powder by inhalation through an air flow path may be accomplished by an inhalation system including a delivery device having a mouthpiece through which the powder is inhaled. The inhalation system includes a dose cassette defining at least one drug cavity containing dry powder of a dose to be delivered and being sealed by a lid. Further, the inhalation system includes a resilient member configured to be introduced into the air flow path to guide/direct the air flow into the drug cavity upon removal of the lid.10-08-2009
20120138056DRY POWDER COMPOSITION COMPRISING CO-JET MILLED PARTICLES FOR PULMONARY INHALATION - The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically active material for pulmonary inhalation, the method comprising a jet milling process.06-07-2012
20120138055INHALER - An inhaler comprising a housing to receive a strip having a plurality of blisters is disclosed. Each blister has a puncturable lid and contains a dose of medicament for inhalation by a user. A mouthpiece is pivotally mounted to the housing through which a dose of medicament is inhaled by a user. The inhaler also has an actuating mechanism including a lever operable to sequentially move each blister into alignment with a blister piercing member depending from the mouthpiece. The actuating lever is also operable to cause the mouthpiece to pivot so that the blister piercing member punctures the lid of an aligned blister so that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway.06-07-2012
20130008442DELIVERY DEVICE AND RELATED METHODS - A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. One or more bypass inlets, two or more dispersion chambers, and/or flow arrangements in which incoming and outgoing flow in a dispersion chamber are transverse may be used to disperse a dose for delivery to a user.01-10-2013
20100132704BLISTER PACK AND APPLICATOR THEREFOR - In a container (06-03-2010
20130014758DRY POWDER FORMULATIONS - A dry powder suitable for inhalation n a dry powder inhaler, the powder comprising a carrier, an active agent and at least 0.5% by weight of magnesium stearate, the powder being further characterized in that the less than 10% of the surface of the carrier material is covered with particles of magnesium stearate. The invention is also directed to a method of making dry powders by blending together the ingredients mentioned in a diffusion blender for a period of time that is less than 60 minutes.01-17-2013
20120240929UNIT DOSE CARTRIDGE AND DRY POWDER INHALER - A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an air flow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section.09-27-2012
20080230058Dry powder dispersing apparatus and methods for their use - The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.09-25-2008
20080223366Inhalation Device - An inhalation device is described for use with a medicament pack in which at least one container for medicament in powder form is defined between two sheets peelably secured to one another. The device comprises means for peeling the sheets apart at an opening station to open the container; and an outlet, communicating with the opened container, through which a user can inhale medicament in powder form from the opened container.09-18-2008
20080223365Inhaler for Powdery Substances, in particular Medicinal Substances - An inhaler for powdered, particularly medicinal substances, is formed with a suction air duct that extends to a mouthpiece, a reservoir for the substance, and an at least linearly movable dosing chamber for separating a specific amount of the substance from the reservoir and placing the amount into a transfer position from where it is transferred to a suction air flow. In order to charge the dosing chamber by separating a specific amount of substance from the reservoir, the dosing chamber can be rotationally moved in a superimposed fashion while being arranged eccentric to a corresponding axis of rotation. A closure slide element closes off the dosing chamber in the transfer position. When suction is applied, the closure slide element moves relative to the dipping plunger into a dose-release position, whereupon the dose of the powdered substance is transferred to the suction air stream formed in the suction air duct.09-18-2008
20120247464Inhalation Apparatus - An inhaler is instantly activated upon its removal from a cover or cover unit, and by rotating a cartridge component of the inhaler with respect to a mouthpiece portion, so as to create a flow pathway for ambient air and particles. The cartridge component includes a chamber, whose contents typically include dry powders or the like. Upon creation of the flow pathway, the contents of the chamber are instantly accessible for immediate inhalation by a user through the mouthpiece portion.10-04-2012
20130112199INHALER FOR POWDERY SUBSTANCES, IN PARTICULAR MEDICINAL SUBSTANCES - An inhaler for powdery, in particular medical, substances is formed with a suction air channel, which leads to a mouthpiece. The inhaler also has a storage chamber for storing the substance and a linearly moving dosing chamber for apportioning a specified amount of substance from the storage chamber to a transfer point to the suction air flow. The aim of the invention is to obtain a structurally simple solution that makes it possible to eliminate adding an external air flow. To this end, a component of the suction air flow, which is located in the direction of extension of the dosing chamber, empties said dosing chamber.05-09-2013
20130092162MEDICINE INHALER AND MEDICINE SUPPLY METHOD - It becomes possible to stably deliver an inhaled particulate medicine to a targeted part for administration while reducing burdens on a patient. When supplying the particulate medicine into a body by an airflow, a multi-layer flow composed of a core airflow (A) and a clad airflow (B) outside the core airflow is used as the airflow. The medicine is dispersed in the core airflow (A) and velocity of the clad airflow (B) is set higher than that of the core airflow (A). The medicine dispersed in the core airflow (A) reaches the targeted part for administration while the medicine is protected by the clad airflow (B) without contacting a larynx and the like. A cross-sectional area of the airflow is set smaller than that of the larynx. The airflow is supplied to an upper side of the larynx.04-18-2013
20130092160COMPOSITIONS, METHODS & SYSTEMS FOR RESPIRATORY DELIVERY OF TWO OR MORE ACTIVE AGENTS - Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.04-18-2013
20130092161Inhaler For Powdered, Particularly Medical Substances - The invention relates to an inhaler for powdered, particularly medical substances, comprising a suction air duct that extends to a mouthpiece, a reservoir for the substance, and an at least linearly movable dosing chamber for separating a specific amount of the substance from the reservoir and placing the amount into a transfer position in order for the same to be transferred to the suction air flow. In order to further develop a generic inhaler in an advantageous manner, especially so as to charge the dosing chamber by separating a specific amount of substance from the reservoir, the dosing chamber can be rotationally moved in a superimposed fashion while being arranged eccentric to a corresponding axis of rotation.04-18-2013
20130098362Nasal Delivery Devices - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container.04-25-2013
20130118490INHALERS WITH AIRWAY DISKS HAVING DISCRETE AIRWAY CHANNELS AND RELATED DISKS AND METHODS - Dry powder inhalers include radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.05-16-2013
20130118491Delivery of Active Agents - A method of introducing a physiologically-active agent into the circulatory system of a mammal is disclosed herein. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent being administered to a patient in need of treatment. In particular, the drug delivery system is designed for pulmonary drug delivery such as by inhalation, for delivery of the active agents such as proteins and peptides to the pulmonary circulation in a therapeutically effective manner avoiding degradation of the active agents in peripheral and vascular tissue before reaching the target site.05-16-2013
20130125888DEVICE FOR SUPPLYING MICRONIZED MEDICAL SALT - The device (05-23-2013
20130125886METHOD OF PREVENTING ADVERSE EFFECTS BY GLP-1 - A method for preventing or reducing adverse effects such as profuse sweating, nausea and vomiting, which normally are associated with subcutaneous and intravenous administration of glucagon-like peptide 1 (GLP-1) therapy is provided. In particular, the method comprises the rapid administration of a GLP-1 formulation into the pulmonary circulation such as by inhalation, directly into pulmonary alveolar capillaries using a dry powder drug delivery system.05-23-2013
20130125885Inhaler - An inhalation device comprising a base having a slot for insertion of a single blister containing a dose of medicament to be inhaled into the base is disclosed. The inhaler has a mouthpiece pivotably mounted to the base which carries a blister piercing element operable to pierce a blister received in said slot when the mouthpiece is pivoted relative to the base. When a user inhales on the mouthpiece, the dose is entrained in an air How and flows out of the blister through the mouthpiece and into the user's airway.05-23-2013
20130125887CRYSTALLINE FORMS OF A BIPHENYL COMPOUND - The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder.05-23-2013
20130125884NOVEL DOSAGE AND FORMULATION - The present disclosure relates to pharmaceutical compositions for inhalation comprising aclidinium in the form of a dry powder of a pharmaceutically acceptable salt in admixture with a pharmaceutically acceptable dry powder carrier, providing a metered nominal dose of aclidinium equivalent to about 200 micrograms aclidinium bromide.05-23-2013
20130133653DRY POWDER INHALERS WITH DUAL PIERCING MEMBERS - A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.05-30-2013
20130139815DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser device comprising: a dose counter for indicating the number of doses that have been dispensed or that remain to be dispensed, said counter comprising: at least one rotary counter element provided with indicator means, such as digits or numbers, and provided with a first set of teeth and with a second set of teeth; a movable actuator element adapted to co-operate with said first set of teeth of said counter element so as to turn it; and anti-return means adapted to co-operate with said second set of teeth so as to prevent said counter element from turning in the direction opposite to the direction that is imposed by said actuator element; said anti-return means comprising a tip that is substantially V-shaped, and that, after each actuation of the counter, co-operates with a respective tooth of said second set of teeth in a blocking position, said tip comprising a first branch that is adapted to co-operate in the blocking position with a blocking shoulder of said tooth, and a second branch that is plane and adapted to co-operate with a plane surface of said teeth, said plane second branch and said plane surface being coplanar when said tip is in the blocking position, said tip being urged resiliently towards said blocking position so as to ensure accurate positioning of said counter element after each actuation of the counter.06-06-2013
20080202514INHALER - A dry powder inhaler has a vibrator coupled to a blister filled with a dry powder drug substance. One or more of drug ejection apertures in the blister are substantially opposite the vibrator. One or more air intake apertures in the blister are not opposite the vibrator. Upon vibration of the vibrator, the drug substance is deaggregated, aerosolized, and ejected from the drug ejection apertures for inhalation by a patient.08-28-2008
20080202513Use of Dry Powder Compositions For Pulmonary Delivery - Use of chitosan or a chitosan derivative in a dry powder composition enhances the release of the dry powder composition containing a medicament from a container and/or the dispersibility in air of the dry powder composition containing a medicament. When the dry powder composition is administered to a person in need thereof by means of a dry powder inhaler, the presence of the chitosan or chitosan derivative enhances the dispersibility of the dry powder composition such that the dose emitted from the container is enhanced and/or the respirable fraction available for deposit in the lungs of a person is increased.08-28-2008
20080196718Medicament Dispenser - A medicament dispenser for use with at least one medicament carrier carrying multiple distinct medicament portions, said medicament dispenser comprising08-21-2008
20080196717Powder Inhaler - The invention consists of a powder inhalator for administrating medications. The inhalator, according to the invention, has a chamber with a mechanism for opening the medication capsule and an aerodynamic chamber in which the medication particles are separated from the currier capsules. In the aerodynamic chamber. On the opposite side to the mouthpiece opening, there are air inlet ducts which form a multidirectional system of air ducts. The air ducts are shaped in a way which makes the air that flows through them create at least three streams. Due to the intersecting of the air streams the air flow is strongly turbulent even if low speeds are involved. Consequently the separation of the active substance particles form the carrier surface is very effective.08-21-2008
20120255548DRY POWDER INHALERS - Dry powder inhalers include electronic displays, readers and/or counters that can decrement dose amounts, inhibit misuse, read data on drug containment devices and/or communicate with remote devices. The dry powder containers can include at least a pair of cooperating generally tubular members, including an inner member and a generally tubular outer member sized and configured to slidably receive the inner member.10-11-2012
20100307494INHALER - An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. The inhaler comprises a mouthpiece cover pivotable to move the blister strip onward.12-09-2010
20100307493DEVICE FOR DISTRIBUTING FLUID PRODUCT - A fluid dispenser device comprising: a body (12-09-2010
20100307492DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser device comprising: a body (12-09-2010
20120272959Device for Producing Dry Aerosol (Varians) - A device for producing dry aerosol, having a casing, an airway with a supply air flow booster, placed in a chamber, connected with an airway through an outlet, a salt mill made in the form of a grinding body with a rotary drive, aerosol concentration detector, connected to a control unit connected to a switch of mill's drive, and in accordance with the invention, an air pipe is fixed in the outbound channel of a chamber, the lower part of which is located atop a grinding body of a mill, and the upper part—in an airway, while on the upper side of an air tube there is an opening directed toward an air flow in an airway, and a gap between a chamber side and mill's grinding body is 3-10 mm, and a gap between a base of a chamber and mills' grinding body is 1-5 mm.11-01-2012
20100313886INHALER - In an inhaler for administering a powdery medicament in the form of an inhalable substance, substance formulation or mixture, a blister cavity to be opened by piercing elements (12-16-2010
20130152927METHOD FOR USING A DRY POWDER INHALER - A method of using a dry-powder inhaler, including providing a dry-powder inhaler (06-20-2013
20130152926DRY POWDER INHALERS THAT INHIBIT AGGLOMERATION, RELATED DEVICES AND METHODS - Inhalers with fins that deagglomerate dry powder using inspiratory effort of a user of an inhaler. The inhaler fins, at least in steady state conditions, are configured to generate dry powder and airflow patterns having turbulence with flow vortices, some of which may have a vortex having an axis of rotation that extends in an inspiratory flow direction while others may have a vortex that is substantially orthogonal to the inspiratory flow direction in an inspiratory airflow path, as an amount of dry powder travels through the inhaler to thereby deagglomerate the dry powder without trapping undue amounts of the dry powder during inhalation.06-20-2013
20130152928DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser, including a cover element; a blister strip; a blister opening mechanism; a first displacement mechanism having an indexer wheel; a second displacement mechanism pivoting between a non-dispensing position and a dispensing position; a cocking member for urging the second displacement mechanism towards the dispensing position, the cocking member spring-loaded by opening the cover; a blocking mechanism for retaining the second displacement mechanism in the non-dispensing position; a trigger mechanism for releasing the blocking mechanism; a slidable carriage displaceable between a non-indexing position and an indexing position and including an actuator co-operating with the indexer wheel; a connection mechanism activated during inhalation that connects the carriage with the cover, so as to displace said carriage towards its indexing position when the cover element is brought towards its closed position, and so as to displace said carriage towards its non-indexing position when brought towards its open position.06-20-2013
20110308519DRY POWDER FORMULATION COMPRISING AN ANTIMUSCARINIC DRUG - The invention provides dry powder formulations suitable for the inhalatory administration by means of a dry powder inhaler, comprising an antimuscarinic drug as active ingredient. The invention also provides processes for the preparation of such a formulation and method for the prevention and/or treatment of a wide range of conditions including respiratory disorders by administering such a formulation.12-22-2011
20130186398DRY POWDER INHALER - A dry-powder inhaler including a body containing a dispersion chamber; a dispenser orifice through which the user inhales; a loading opening that receives a capsule containing a dose of dry powder for inhaling; and at least one movable portion that moves relative to the body between a first end position and a second end position; the dispersion chamber containing at least a portion of an empty capsule at the moment of inhalation, the at least one capsule portion swirling in the dispersion chamber during inhalation so as to disperse and/or break up the powder.07-25-2013
20120017903DOSING DEVICE - The invention relates to a dosing device for inhaling a powdery substance, particularly of a medical nature, which is arranged in a storage chamber above a trailing bottom and can be brought from said storage chamber into an evacuation readiness position, and having a display (A) associated with the actual filling level in the area of the device wall. In order to further develop a dosing device of the type in question particularly with regard to an improved display in an advantageous manner, it is proposed that the display (A) be composed of a strip tape carried along by the bottom and deflected by 01-26-2012
20120017902ELASTOMERIC DISCHARGE MEMBER FOR NASAL DELIVERY DEVICE - Various embodiments of the present invention provide a delivery device (01-26-2012
20120291781DRY POWDER DELIVERY DEVICE - A method of flowing a medicament containing powder using gas, including, providing a volume of a gas according to one or more release conditions; directing flow of said gas through or adjacent a powder including a medicament; and releasing a therapeutically effective amount of said powder using said gas. Optionally, the releasing comprises releasing according to breath considerations. Optionally or alternatively, the releasing comprises releasing according to time considerations. In an exemplary embodiment of the invention, the powder is held in a capsule that has apertures formed therein.11-22-2012
20130199527DRY POWDER INHALER AND SYSTEM FOR DRUG DELIVERY - A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.08-08-2013
20120298106DISPENSER AND METHOD FOR ENTRAINING POWDER IN AN AIRFLOW - The disclosure relates to a device for inhalation of at least one air stream carrying a dose of medicament powder. The device comprises a powder-containing cavity which opens into a flow passage. The flow passage is arranged to direct an inhalation air flow across the cavity opening. A circulating flow is thereby induced in the cavity by the phenomenon of shear driven cavity flow. Powder is entrained in the circulating flow and deaggregated before exiting the cavity and becoming entrained in the flow of air along the flow passage.11-29-2012

Patent applications in class Particulate treating agent carried by breathed gas