Class / Patent application number | Description | Number of patent applications / Date published |
073640470 | Osmotic pressure (e.g., diffusion characteristic) | 23 |
20080264151 | SYSTEMS AND METHODS FOR A SAMPLE FLUID COLLECTION DEVICE - A fluid collection device comprising a body comprising a capsule interface, and a capsule configured to interface with the body via the capsule interface and configured to hold a sample receiving chip. The sample receiving chip comprises a substrate that receives an aliquot volume of a sample fluid, wherein the substrate is operatively shaped to receive the aliquot volume of sample fluid through capillary action, and a sample region of the substrate, sized such that the volume of the sample fluid is sufficient to operatively cover a portion of the sample region, whereupon energy properties of the sample fluid can be transduced to produce a sample fluid reading. | 10-30-2008 |
20080264152 | BIOMARKER NORMALIZATION - In accordance with the invention, a fluid sample is measured with a tear film measuring system that includes a processing device that receives a sample chip comprising a sample region configured to contain an aliquot volume of sample fluid, the processing device configured to perform analyses of osmolarity and of one or more biomarkers within the sample fluid, wherein the analysis of biomarkers includes normalization of biomarker concentration values. | 10-30-2008 |
20080289403 | DEVICE FOR MEASURING LOAD LOSS IN REVERSE OSMOSIS MEMBRANE CONTAINERS - The device is applicable to systems that comprise a pressure containing tube ( | 11-27-2008 |
20090241647 | Tear Film Osmometry - Osmolarity measurement of a sample fluid, such as tear film, is achieved by depositing an aliquot-sized sample on a sample receiving substrate. The sample fluid is placed on a sample region of the substrate. Energy is imparted to the sample fluid and energy properties of the fluid can be detected to produce a sample fluid reading that indicates osmolarity of the sample fluid. An aliquot-sized volume can comprise, for example, a volume of no more than 20 microliters (μL). The aliquot-sized sample volume can be quickly and easily obtained, even from dry eye sufferers. The imparted energy can comprise electrical, optical or thermal energy. In the case of electrical energy, the energy property of the sample fluid can comprise electrical conductivity. In the case of optical energy, the energy property can comprise fluorescence. In the case of thermal energy, the measured property can be the freezing point of the sample fluid. The substrate can be packaged into a chip, such as by using semiconductor fabrication techniques. An ex vivo osmolarity sensor system that uses the chip can detect energy from the sample region and can provide an accurate osmolarity measurement without user intervention. | 10-01-2009 |
20090260425 | OSMOTIC REACTION DETECTOR FOR MONITORING BIOLOGICAL AND NON-BIOLOGICAL REACTIONS - An apparatus and system for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes of reaction detector. The reaction detector is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10 | 10-22-2009 |
20090320573 | OSMOTIC REACTION DETECTOR FOR MONITORING BIOLOGICAL AND NON-BIOLOGICAL REACTIONS - A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes in a reaction cell. The reaction cell is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10 | 12-31-2009 |
20100071445 | APPARATUS FOR MEASURING DIFFUSION OF TRANSDERMAL ABSORPTION PREPARATION - This invention is to provide a diffusion testing device to facilitate determination of diffusivity of prolonged release of drugs from transdermal therapeutic preparation. | 03-25-2010 |
20100071446 | SOLUTE CONCENTRATION MEASUREMENT DEVICE AND RELATED METHODS - A solute concentration measurement device is disclosed. The device may comprise a filter membrane, an exchange chamber, a sensing chamber, a separator, and a sensor. The device may be configured to be placed in fluid communication with a sample solution containing a solute and a solvent. The filter membrane may provide selective fluid communication between the solution and the exchange chamber. The separator may separate the exchange chamber from the sensing chamber and cause a change in a condition of the sensing chamber corresponding to a change of a condition of the exchange chamber. The sensor may sense the condition pertaining to the sensing chamber and calculate the concentration of the sample solution corresponding to this change. | 03-25-2010 |
20100223981 | APPARATUS AND METHOD FOR MEASURING AUGMENTED OSMOTIC PRESSURE IN A REFERENCE CAVITY - An apparatus and method for measuring augmented osmotic pressure in a reference cavity is provided, in which the device comprise a substrate frame ( | 09-09-2010 |
20100300182 | DEVICES AND METHODS TO SIMULATE AN OCULAR ENVIRONMENT - Methods and devices used to simulate the use of an ophthalmic lens contained in an ocular environment are disclosed herein. | 12-02-2010 |
20110011166 | SYSTEMS AND METHODS FOR COLLECTING TEAR FILM AND MEASURING TEAR FILM OSMOLARITY - A sample receiving chip comprising a substrate that receives an aliquot volume of a sample fluid and a sample region of the substrate, sized such that the volume of the sample fluid is sufficient to operatively cover a portion of the sample region. The energy imparted into the sample fluid is transduced by the sample region to produce an output signal that indicates energy properties of the sample fluid. The sample receiving chip also includes a channel formed in the substrate, the channel configured to collect the aliquot volume of a sample fluid and transfer the aliquot volume of sample fluid to the sample region. | 01-20-2011 |
20110120214 | TRANSDERMAL DIFFUSION CELL TESTING VESSEL AND METHODS USING SAME - Vessel for transdermal diffusion cell testing includes a container defining an interior chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is arranged above the inlet port of the chamber, proximate the opening of the chamber, and is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. Tilting of the vessel prior to or during introduction of solution prevents air bubbles from remaining between the skin and the solution. | 05-26-2011 |
20110120215 | Transdermal Diffusion Cell Testing Arrangements and Methods - Transdermal diffusion cell testing vessel includes a container defining a chamber having an opening against which skin is placed, and a casing arranged partially around and spaced apart from part of the container to define a compartment therebetween. The chamber retains a saline solution and is not in flow communication with the compartment through which water is circulated. The vessel includes separate inlet ports and outlet ports, each including a conduit communicating with the chamber or compartment. The outlet port of the chamber is angled downward relative to a horizontal upper surface of the container against which skin being tested is placed. The vessel is used for conducting transdermal diffusion cell testing in combination with a solution source fluidly coupled to each vessel, a waste receptacle fluidly coupled to each vessel, a syringe pump fluidly coupled to a respective vessel, and a sample collector fluidly coupled to the syringe pump(s). | 05-26-2011 |
20120060590 | BIOMARKER NORMALIZATION - A fluid sample is measured with a tear film measuring system that includes a processing device that receives a sample chip comprising a sample region configured to contain an aliquot volume of sample fluid, the processing device configured to perform analyses of osmolarity and of one or more biomarkers within the sample fluid, wherein the analysis of biomarkers includes normalization of biomarker concentration values. | 03-15-2012 |
20120067112 | Systems and Methods for a Sample Fluid Collection Device - A fluid collection device comprising a body comprising a capsule interface, and a capsule configured to interface with the body via the capsule interface and configured to hold a sample receiving chip. The sample receiving chip comprises a substrate that receives an aliquot volume of a sample fluid, wherein the substrate is operatively shaped to receive the aliquot volume of sample fluid through capillary action, and a sample region of the substrate, sized such that the volume of the sample fluid is sufficient to operatively cover a portion of the sample region, whereupon energy properties of the sample fluid can be transduced to produce a sample fluid reading. | 03-22-2012 |
20120090388 | SYSTEMS AND METHODS FOR COLLECTING TEAR FILM AND MEASURING TEAR FILM OSMOLARITY - A sample receiving chip comprising a substrate that receives an aliquot volume of a sample fluid and a sample region of the substrate, sized such that the volume of the sample fluid is sufficient to operatively cover a portion of the sample region. The energy imparted into the sample fluid is transduced by the sample region to produce an output signal that indicates energy properties of the sample fluid. The sample receiving chip also includes a channel formed in the substrate, the channel configured to collect the aliquot volume of a sample fluid and transfer the aliquot volume of sample fluid to the sample region. | 04-19-2012 |
20120160019 | MICRO-FLUIDIC TEST APPARATUS AND METHOD - An apparatus, system, and method for determining the osmolarity of a fluid. The apparatus includes at least one micro-fluidic circuit and at least one electrical circuit disposed in communication with the micro-fluidic circuit for determining a property of a fluid contained within the at least one micro-fluidic circuit. | 06-28-2012 |
20120234083 | DEVICE AND METHOD FOR TESTING REVERSE OSMOSIS MEMBRANES - The device for testing reverse osmosis membranes provides for the quick and efficient testing of the transport properties of reverse osmosis membranes at a fixed pressure over a fixed period of time. The device includes a first chamber adapted for receiving a volume of de-ionized water and a second chamber adapted for receiving a volume of brine. In use, a reverse osmosis membrane to be tested is clamped between the first and second chambers and a pressurized inert gas, such as gaseous nitrogen, is injected into the second chamber at known pressure to initiate reverse osmosis transport. The transport is carried out at the known pressure for a fixed period of time, after which the concentration of brine volume of water in the first chamber is measured. | 09-20-2012 |
20130233061 | BIOMARKER NORMALIZATION - A fluid sample is measured with a tear film measuring system that includes is processing device that receives a sample chip comprising a sample region configured to contain an aliquot volume of sample fluid, the processing device configured to perform analyses of osmolarity and of one or more biomarkers within the sample fluid, wherein the analysis of biomarkers includes normalization of biomarker concentration values. | 09-12-2013 |
20140137641 | SOLUTE CONCENTRATION MEASUREMENT DEVICE AND RELATED METHODS - A solute concentration measurement device is disclosed. The device may comprise a filter membrane, an exchange chamber, a sensing chamber, a separator, and a sensor. The device may be configured to be placed in fluid communication with a sample solution containing a solute and a solvent. The filter membrane may provide selective fluid communication between the solution and the exchange chamber. The separator may separate the exchange chamber from the sensing chamber and cause a change in a condition of the sensing chamber corresponding to a change of a condition of the exchange chamber. The sensor may sense the condition pertaining to the sensing chamber and calculate the concentration of the sample solution corresponding to this change. | 05-22-2014 |
20140150538 | SENSOR FOR DETECTING THE QUALITY OF A FLUID - A device for measuring the quality of an operating substance and/or additive, in particular a reduction agent, stored in a tank, includes a reference container connected to the operating substance and/or the additive via a semi-permeable diaphragm, in which the reference container is filled with a medium which has a known osmotic pressure relative to the used operating substance and/or additive. | 06-05-2014 |
20140326056 | Method for Quick Assessment of Osmolarity - An osmolarity measuring device for providing a semi-quantitative color measure of liquid's osmolarity, said device comprising: a. none or more coloring agents; b. none or more swelling agents; c. none or more solutions; d. a vesicle with a continuous integument, containing within said integument at least one of a group consisting of said coloring agent, said swelling agent and said solution; and e. a support of absorbent material impregnated in at least one area with a plurality of said vesicles; wherein the apparent color of said area alters if the osmolarity of said liquid is within a pre-determined range. | 11-06-2014 |
20150343383 | REVERSE OSMOSIS EQUIPMENT PERFORMANCE CALCULATION METHOD, REVERSE OSMOSIS EQUIPMENT PERFORMANCE CALCULATION DEVICE AND PROGRAM - An input condition setting unit of a reverse osmosis equipment performance calculation device displays an input condition setting screen for calculating operational performance of reverse osmosis equipment on a displaying device. A calculation condition list generating unit generates a calculation condition list for a plurality of cases on the basis of the input conditions set via the input condition setting screen. An operational performance calculating unit sequentially extracts calculation conditions for one case from the calculation condition list and repeatedly performs operational performance calculations for the calculation conditions for the plurality of cases. A calculation result displaying unit displays a list of the calculation results for the plurality of cases obtained by the operational performance calculations on the displaying device. | 12-03-2015 |