| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 073610550 |
Including sampling, sample handling, or sample preparation
| 69 |
| 073610560 |
Detail of fluid handling means (e.g., valve, control, etc.)
| 31 |
| 073610530 |
Column detail
| 22 |
| 073610570 |
With detail of compensation or regulating means | 5 |
| 20100162801 | METHOD AND APPARATUS FOR ANALYSIS BY LIQUID CHROMATOGRAPHY - In order to obtain a temperature gradient elution method which is rapid and accurate, a mobile phase ( | 07-01-2010 |
| 20100236324 | COLUMN TIP PROCESSING DEVICE AND COLUMN TIP PROCESSING METHOD - The present invention relates to a column tip processing device and a column tip processing method, and its objective is to enhance the contact between a packing and a fluid as a subject to be processed whereby accomplishing a highly efficient reaction as well as an accurate processing, which has a nozzle head having a single or multiple-channeled nozzle, a suction and discharge mechanism, one or more types of column tips in which a packing is enclosed, a stage provided with a fluid housing part group including a plurality of fluid housing parts in which various solutions are or can be housed, and moving means for moving the nozzle head relatively to the fluid housing part group, and also has a controlling part which controls the suction and discharge mechanism and the moving means with regard to quantities, pressure, flow rate, the number of cycles, time or position of the suction or discharge by the nozzle based on a structural requirement relating to the structure of the one or more types of column tips to be fitted to the nozzle and a processing requirement relating to the processing contents involving one or more types of subject fluids subjected to the suction or discharge of the column tips. | 09-23-2010 |
| 20080282780 | Sire Flow Detector - The present invention concerns a device and a method for the rapid detection of a low molecular substance in a liquid flow. | 11-20-2008 |
| 20120304746 | THERMAL-BASED FLOW SENSING APPARATUSES AND METHODS FOR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY - One aspect of the invention provides a flow sensing apparatus including: a fluid channel that allows a fluid to flow in a first direction; a first thermoelectric sensing element arranged at a first position along the fluid channel such that it senses a temperature of the fluid; a second thermoelectric sensing element arranged at a second position along the fluid channel and separated from the first sensing element by a predetermined distance along the fluid channel; and a heating element arranged between the first and second thermoelectric sensing elements, the heating element being equally spaced from the first and second thermoelectric sensing elements. | 12-06-2012 |
| 20130014569 | THERMAL-BASED FLOW SENSING APPARATUS AND METHOD FOR HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY - One aspect of the invention provides a flow sensing apparatus for sensing fluid flow in a nano-scale high-performance liquid chromatography apparatus. The flow sensing apparatus includes: a fluid channel that allows a fluid to flow in a first direction; a first infrared sensor arranged at a first position along the fluid channel such that it senses a temperature of the fluid; a second infrared sensor arranged at a second position along the fluid channel and separated from the first sensor by a predetermined distance along the fluid channel; and a heating element arranged between the first and second infrared sensors. The heating element is equally spaced from the first and second infrared sensors. | 01-17-2013 |
| 073610580 |
Detector detail | 4 |
| 20130091936 | ELECTROCHEMICAL DETECTION CELL FOR LIQUID CHROMATOGRAPHY SYSTEM - A detection cell for a chromatography system includes a cell body having an inlet, an outlet, and a counter electrode, a working electrode, a sample flow passageway extending between the inlet and the outlet and in fluid contact with the counter and working electrodes, and a palladium/noble metal reference electrode system. A method of using the detection cell is also described. | 04-18-2013 |
| 20080271520 | LIQUID CHROMATOGRAPHIC ANALYZER AND LIQUID CHROMATOGRAPHY ANALYSIS - An apparatus for liquid chromatography which detects ingredients by an electrolytic device, wherein the apparatus can detect many kinds of substances in high sensitivity by making possible to apply a wider range of electrolyzing voltage than former apparatus. | 11-06-2008 |
| 20110100100 | Fluid Separation Conduit Cartridge - A fluid separation conduit cartridge comprising a fluid separation conduit is disclosed. In certain embodiments the fluid separation conduit is potted to provide operation at increased pressures. In other embodiments, the fluid separation conduit cartridge has one or more memory units. The memory units are operative to store data such as, for example, cartridge usage and test results. | 05-05-2011 |
| 20080276694 | Analytical Methods For 2-Deoxy-D-Glucose - 2-Deoxy-2-D-glucose (2-DG) concentration and purity can be measured in a sample of crystalline or liquid by HPLC with accuracy and precision suitable for analysis of active pharmaceutical ingredient and drug product. | 11-13-2008 |
| 073610540 |
Paper or thin layer type | 2 |
| 20130067996 | SAMPLE DETECTION METHOD BY THIN-LAYER CHROMATOGRAPHY, THIN-LAYER CHROMATOGRAPHY PLATE, AND METHOD FOR PRODUCING SAME - The present invention provides a thin-layer chromatography plate and a thin-layer chromatography that can detect the separation of a component in a sample by a separating agent layer that does not permit the detection of the separation of the component in the sample by an optical response. For a sample that has an optical response to ultraviolet light or a coloring agent, the present invention uses a thin-layer chromatography plate that has a first separating agent layer, which has the same optical response as the sample, and a second separating agent layer, which is disposed adjacent thereto and has an optical response that is different from the aforementioned optical response; carries out development of the sample in the first separating agent layer; thereafter carries out further development of the spots from the first separating agent layer toward the second separating agent layer; and detects the spots in the second separating agent layer through exposure to ultraviolet radiation or a color-development treatment with a coloring agent. In addition, the development axis in the first separating agent layer is maintained approximately perpendicular, and spot broadening at the boundary surface is prevented by adjusting the binder blending ratio. | 03-21-2013 |
| 20110214487 | ELECTRO-SPUN FIBERS AND APPLICATIONS THEREFORE - A supported nanofiber medium useful for segregating chemical species is provided by selecting a polymer, selecting a substrate; and electrospinning the polymer to form a nanofiber medium on the supporting substrate. When the substrate is a planar surface, the nanofiber medium will be a mat suitable for conducting chromatographic separation. When the substrate is a filament, the nanofiber medium is an annular mat suitable for solid phase microextraction. The nanofiber media formed may be selectively cross-linked and at least partially carbonized to carbon nanofibers. The nanofiber medium is supported on the substrate without the use of binder material. | 09-08-2011 |
| Entries |
| Document | Title | Date |
|---|
| 20090044606 | Robust Carbon Monolith Having Hierarchical Porosity - A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores. | 02-19-2009 |
| 20130031965 | METHOD OF TESTING FOR A MILK TRISACCHARIDE - A method of testing for a trisaccharide in milk includes the step of providing a predetermined amount of milk. The method also includes the step of isolating a trisachharide of the milk with a hydride insertion reaction to identify the molecule as phosphorylated. Also included in the method is the step of obtaining a mass spectrum of the isolated milk trisaccharide sample. The method further includes the step of identifying a molecular structure of the isolated milk trisaccharide sample. | 02-07-2013 |
| 20130074585 | PROCESS FOR PRODUCING SUGAR CHAIN DERIVATIVE, STRUCTURE ANALYSIS METHOD, AND SUGAR CHAIN DERIVATIVE - A process for preparing an oligosaccharide derivative from an oligosaccharide mixture, the process being characterized in that the process comprises the steps of (a) introducing a lipophilic group into oligosaccharides of the mixture to obtain a mixture of oligosaccharide derivatives, and (b) treating the oligosaccharide derivative mixture by serotonin affinity column chromatography. | 03-28-2013 |
| 20100162800 | MEDIA COMPOSITIONS FOR ELUTING COMPOUNDS FROM MATRICES AND METHODS FOR MAKING AND USING THEM - Embodiments of the invention provide to apparatuses and media used in drug elution studies and methods for making and using them. One embodiment of the invention is a drug elution method that can be used for in-vitro studies of a matrix impregnated with a compound such as a drug blended polymer matrix. Such methods and materials can be used for example to assess and control the manufacturing process variability of drug eluting implantable devices such as cardiac leads. | 07-01-2010 |
| 20110302997 | LIQUID CHROMATOGRAPH APPARATUS - A liquid chromatograph apparatus capable of eliminating a deviation of measurement results originating from an instrumental error is provided. | 12-15-2011 |
| 20100126254 | Method for Screening Urine for Organic Acids - The present teachings relate to systems and screening methods for measuring organic acids in urine samples. | 05-27-2010 |
| 20110203352 | METHOD AND DEVICE FOR DIRECT QUANTITATIVE DETERMINATION OF PESTICIDE SEED LOADING ON INDIVIDUAL SEEDS - The present invention provides methods and devices for the direct quantitative analysis of multiple pesticides on individual seeds with or without fluorescent pigments. The seed varieties include corn, cotton, wheat, soybean and canola. | 08-25-2011 |
| 20110219858 | COMPOSITION FOR USE AS A PEPTIDE RETENTION STANDARD AND A METHOD OF PREDICTING PEPTIDE HYDROPHOBICITY IN LIQUID CHROMATOGRAPHY - A composition comprising synthetic peptides for use as a peptide retention standard in liquid chromatography applications is disclosed Said synthetic peptides have a broad range of hydrophobicity while maintaining low variation in their molecular weights The synthetic peptides disclosed consist of the ammo acid sequences LGGGGGGDGSR, LGGGGGGDFR, LLGGGGDFG, LLLGGDFR, LLLLDFR, LLLLLDFR A method of predicting the hydrophobicity of an unknown peptide in liquid chromatography using a composition of peptide retention standards and a method of developing a Universal Hydrophobicity Index (UHI) for the measurement of peptide hydrophobicity in liquid chromatography are also described | 09-15-2011 |
| 20090188305 | Reference standard for characterization of rosuvastatin - Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin. | 07-30-2009 |
| 20110107822 | Interfacing With A Digital Microfluidic Device - Described are techniques for use in connection with analyzing a droplet. One or more droplets of a sample are formed on a surface of a digital microfluidic device. The droplets are manipulated to perform processing using said one or more droplets generating one or more resulting droplets. The one or more resulting droplets may be transferred from the microfluidic device to another device for analysis. The one or more droplets may also be provided to the digital microfluidic device from yet another device or analysis instrument. | 05-12-2011 |
| 20100288024 | DEGASIFIER AND LIQUID CHROMATOGRAPH EQUIPPED THEREWITH - The present invention relates to a deaerator | 11-18-2010 |
| 20110041589 | NEW HPCL METHOD - The present invention relates to new HPLC methods for the analysis of the drug substance clopidogrel and related substances. In a first method the mobile phase comprises two or more liquids, and the relative concentration of the liquids is varied to a predetermined gradient. In a second method the mobile phase comprises a polar protic organic solvent, and the stationary phase comprises a gel. The present invention also relates to a method for analysing a substance, comprising the detection and optional quantification of one or more specific impurities. | 02-24-2011 |
| 20100058840 | NEBULIZER WASTE PRESSURE REDUCER FOR HPLC SYSTEMS - A High Performance Liquid Chromatography (HPLC) system including a pressure reducer assembly for reducing pressurized streams to ambient pressure. The pressure reducer assembly includes first and second flow restrictors, each coupled to a common chamber that acts as a surge suppressor that mitigates pressure spikes in the discharge lines. The flow restrictors may comprise tubes having a high length-to-diameter ratio. The pressure losses through the flow restrictors, in combination with transition losses as the flow stream enters and exits the chamber, are sufficient to reduce a discharge stream from a specified inlet pressure to substantially ambient pressure, thus eliminating the need for pressurized waste containers. | 03-11-2010 |
| 20110072891 | CONTINUOUS COUNTERCURRENT TANGENTIAL CHROMATOGRAPHY (CCTC) - The present invention is a system for continuous, single-pass countercurrent tangential chromatography having multiple single-pass modules. A single-pass binding step module is used for binding product from an unpurified product solution with a resin slurry. A single-pass washing step module is used for washing impurities from the resin slurry. A single-pass elution step module for eluting an output of the washing step module is used as purified product solution. A single-pass regeneration step module is used for regenerating the resin slurry. In the current invention, the resin slurry flows in a continuous, single-pass through each of the single-pass modules, and one or more of the single-pass modules comprise two or more stages with permeate flow directed countercurrent to resin slurry flow within that single-pass module. The present invention replaces conventional column chromatography and may be made disposable. | 03-31-2011 |
| 20110113866 | Microengineered Supercritical Fluid Chromatography System - This invention describes a microengineered SFC system for rapidly and efficiently separating the constituents of a complex mixture. The SFC system includes a microchannel that is microfabricated from a suitable substrate so that it forms a chromatographic column for separation of chemicals. The surface area of the microchannel of the column is sufficiently small as to permit use of miniature and relatively inexpensive pumps, and the thermal mass of the microengineered column is sufficiently low as to permit rapid temperature cycling using a miniature, low power and inexpensive heating element. At least a portion of this microchannel is packed with suitable sorbent materials or includes surfaces which are suitably coated with sorbent, or both, so as to retain and elute analyte under certain conditions. As a result analyte passing within this microchannel undergoes chromatographic separation. | 05-19-2011 |
| 20100307226 | APPARATUS, KITS AND METHODS FOR DETERMINING THE PRESENCE OR ABSENCE OF MINERALOCORTICOIDS IN SAMPLES - Embodiments of the present invention feature apparatus, kits and methods for detecting the presence or absence of a mineralocorticoid in biological samples. The methods, apparatus and kits feature a high performance liquid chromatography system with a column for receiving one or more biological samples potentially having mineralocorticoid, said chromatography system receiving one or more biological samples at a first time and separating the compounds in retained peaks comprising at least mineral corticoid retained peak for a mineralocorticoid in the event said mineralocorticoid is present at a mineralocorticoid retention time. And, a mass spectrometer in fluid communication with the high performance liquid chromatography system receives one or more of said retained peaks including the mineralocorticoid retained peak at the mineralocorticoid retention time, and produces a signal to allow said mineralocorticoid to be identified by retention peak and mass charge values. | 12-09-2010 |
| 20110259089 | Devices Having An Inert Surface And Methods Of Making Same - The present invention features devices and methods of making such devices for performing liquid chromatography having at least one wetted surface having a composition of a polysilazane. | 10-27-2011 |
| 20110005304 | FLOW CONTROL IN HIGH PERFORMANCE LIQUID CHROMATOGRAPHY - A method for controlling the flow of liquid in a high performance liquid chromatography apparatus. The method includes operating a pump, measuring the liquid pressure downstream of the pump, measuring the liquid flow rate downstream of the pump, and controlling the operation of the pump. In the method, it is automatically determined whether the pump is controlled to achieve a desired pressure or controlled to achieve a desired flow rate. Fuzzy logic can be applied in the method to determine the switch between the control modes. | 01-13-2011 |
| 20110138889 | Method of evaluating prostatic disease - According to the method of evaluating prostatic disease of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject is evaluated based on the concentration value of at least one of Tau, Thr, Ser, Asn, Glu, Pro, Gly, Ala, Cit, ABA, Val, Met, Ile, Leu, Phe, His, Trp, Orn, Lys, and Cys2 contained in the measured amino acid concentration data of the subject. | 06-16-2011 |
| 20090173146 | Temperature programmed low thermal mass fast liquid chromatography analysis system - A temperature programmed low thermal mass fast liquid chromatography system capable of high throughput and low power consumption includes a straight or curved short reloadable low-mass tubular heater with a capillary column extending inside. If the capillary column is long enough, it is coiled to form a coiled capillary LC column (the length of which does not exceed 0.2 m-1.0 m) packed in a singular module package with a heating wire and a temperature sensing wire extending along and in proximity to the LC capillary column. A tubular heater, e.g. a steel tubing, incorporates the LC capillary column, along with the heating wire and the temperatures sensor and is coiled to form a miniature power saving LC module which may be attached outside a chromatography oven. Capillary lengths extend inside the oven between the inlet and outlet of the LC column module and mobile phase source and detector, respectively. An electronic temperature control block is positioned outside the oven cavity and controls the heating of the capillary LC column, as well as other heated zones in the system. | 07-09-2009 |
| 20090320571 | DISPERSION AND SEPARATION OF NANOSTRUCTURED CARBON IN ORGANIC SOLVENTS - The present invention relates to dispersions of nanostructured carbon in organic solvents containing alkyl amide compounds and/or diamide compounds. The invention also relates to methods of dispersing nanostructured carbon in organic solvents and methods of mobilizing nanostructured carbon. Also disclosed are methods of determining the purity of nanostructured carbon. | 12-31-2009 |
| 20110088457 | COMPOSITIONS, SYSTEMS AND METHODS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH AZETIDINE-2-CARBOXYLIC ACID - Methods and systems for detecting azetidine-2-carboxylic acid (Aze) in food consumable by humans and animals are provided. Also provided are methods and systems for inactivating Aze in food and byproducts, as well as other methods for the diagnosis, prevention, and treatment of disorders associated with Aze. | 04-21-2011 |
| 20120160015 | METHODS FOR PREDICTING FOULING TENDENCIES OF HYDROCARBON CONTAINING FEEDSTOCKS - Disclosed is a method involving the steps of (a) precipitating an amount of asphaltenes from a liquid sample of a first hydrocarbon-containing feedstock having solvated asphaltenes therein with one or more first solvents in a column; (b) determining one or more solubility characteristics of the precipitated asphaltenes; (c) analyzing the one or more solubility characteristics of the precipitated asphaltenes; and (d) correlating a measurement of feedstock fouling tendencies for the first hydrocarbon-containing feedstock sample with a mathematical parameter derived from the results of analyzing the one or more solubility characteristics of the precipitated asphaltenes. | 06-28-2012 |
| 20120167671 | METHOD AND APPARATUS FOR TESTING TRANSDERMAL MEDICAMENTS - The invention relates to an apparatus and method for testing transdermal medicaments, wherein the sample tested in a membrane penetration cell resides in the open sample compartment of said cell and is exposed to environmental factors such as temperature, air flow, light and air humidity during testing the absorption and penetration. | 07-05-2012 |
| 20120324986 | SPECTRAL AND TEMPORAL LASER FLUORESCENCE ANALYSIS SUCH AS FOR NATURAL AQUATIC ENVIRONMENTS - An Advanced Laser Fluorometer (ALF) can combine spectrally and temporally resolved measurements of laser-stimulated emission (LSE) for characterization of dissolved and particulate matter, including fluorescence constituents, in liquids. Spectral deconvolution (SDC) analysis of LSE spectral measurements can accurately retrieve information about individual fluorescent bands, such as can be attributed to chlorophyll-a (Chl-a), phycobiliprotein (PBP) pigments, or chromophoric dissolved organic matter (CDOM), among others. Improved physiological assessments of photosynthesizing organisms can use SDC analysis and temporal LSE measurements to assess variable fluorescence corrected for SDC-retrieved background fluorescence. Fluorescence assessments of Chl-a concentration based on LSE spectral measurements can be improved using photo-physiological information from temporal measurements. Quantitative assessments of PBP pigments, CDOM, and other fluorescent constituents, as well as basic structural characterizations of photosynthesizing populations, can be performed using SDC analysis of LSE spectral measurements. | 12-27-2012 |
| 20130008237 | NEEDLE SEAL FORCE SENSOR - Described are techniques for force sensing. A computing device is configured to have a desired force setting. A first vertical position of a needle is determined using the computer device. A control signal is sent from the computing device to a positioning device. In response to the control signal, the needle is positioned at the first vertical position. When in the first vertical position, surfaces of a tip of the needle are in contact with surfaces of an opening of a sealing member and positioning the needle causes application of a force at surfaces of the opening in contact with surfaces of the tip of the needle. In response to application of the force, a spring is compressed a distance that is proportional to the force. The force is measured using a force sensor. | 01-10-2013 |
| 20130008238 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE - The present invention provides a processes for preparing 5-Azacytidine, and intermediates thereof. The present invention further provides an analytical method for determining the purity of 5-Azacytidine in a sample. | 01-10-2013 |
