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Combinatorial chemistry technology: method, library, apparatus

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Class / Patent application numberDescriptionNumber of patent applications / Date published
506007000 METHOD OF SCREENING A LIBRARY 3563
506013000 LIBRARY, PER SE (E.G., ARRAY, MIXTURE, IN SILICO, ETC.) 812
506002000 METHOD SPECIALLY ADAPTED FOR IDENTIFYING A LIBRARY MEMBER 498
506033000 APPARATUS SPECIALLY ADAPTED FOR USE IN COMBINATORIAL CHEMISTRY OR WITH A LIBRARY 454
506023000 METHOD OF CREATING A LIBRARY (E.G., COMBINATORIAL SYNTHESIS, ETC.) 325
506001000 DIRECTED MOLECULAR EVOLUTION OF MACROMOLECULES (E.G., RNA, DNA, PROTEINS, ETC.) 60
506043000 MISCELLANEOUS 1
20080293596Systems and Methods for the Generation of Crystalline Polymorphs - The present invention relates to systems and methods for generating polymorphs of compounds. In particular, the present invention provides high throughput systems and methods for generating and identifying new crystalline polymorphs that find use as improved drugs, pigments, explosives, nonlinear optical crystals, solid-state reactive compounds, and other polymorphic materials.11-27-2008
506041000 TAG OR LABEL SPECIALLY ADAPTED FOR COMBINATORIAL CHEMISTRY OR A LIBRARY (E.G., FLUORESCENT TAG, BAR CODE, ETC.) 1
20120270757SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6.10-25-2012
506042000 LINK OR SPACER SPECIALLY ADAPTED FOR COMBINATORIAL CHEMISTRY OR A LIBRARY (E.G., TRACELESS LINKER, SAFETY-CATCH LINKER, ETC.) 1
20090239770DETECTION OLIGOMER AND METHOD FOR CONTROLLING QUALITY OF BIOCHIP USING DETECTION OLIGOMER - A detection oligomer and method for controlling the quality of a biochip using the detection oligomer are provided. The detection oligomer includes a template having a first and second end and having a sequence that is complementary to a specific sequence of an oligomer, and a hairpin connected to the first end of the template.09-24-2009

Patent applications in all subclasses Combinatorial chemistry technology: method, library, apparatus