| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 436501000 |
BIOSPECIFIC LIGAND BINDING ASSAY
| 591 |
| 436164000 |
OPTICAL RESULT
| 268 |
| 436518000 |
INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS
| 257 |
| 436086000 |
PEPTIDE, PROTEIN OR AMINO ACID
| 241 |
| 436091000 |
HETEROCYCLIC CARBON COMPOUND (I.E., O, S, N, SE, TE, AS ONLY RING HETERO ATOM)
| 217 |
| 436174000 |
INCLUDING SAMPLE PREPARATION
| 144 |
| 436043000 |
AUTOMATED CHEMICAL ANALYSIS
| 105 |
| 436073000 |
METAL OR METAL CONTAINING
| 77 |
| 436008000 |
COMPOSITION FOR STANDARDIZATION, CALIBRATION, SIMULATION, STABILIZATION, PREPARATION OR PRESERVATION; PROCESSES OF USE IN PREPARATION FOR CHEMICAL TESTING
| 72 |
| 436149000 |
MEASUREMENT OF ELECTRICAL OR MAGNETIC PROPERTY OR THERMAL CONDUCTIVITY
| 60 |
| 436127000 |
OXYGEN CONTAINING
| 58 |
| 436106000 |
NITROGEN CONTAINING
| 53 |
| 436071000 |
LIPIDS, TRIGLYCERIDES, CHOLESTEROL, OR LIPOPROTEINS
| 41 |
| 436063000 |
BIOLOGICAL CELLULAR MATERIAL TESTED
| 31 |
| 436536000 |
INVOLVING IMMUNE COMPLEX FORMED IN LIQUID PHASE
| 27 |
| 436163000 |
INCLUDING TITRATION OR PH DETERMINATION
| 27 |
| 436002000 |
PROCESS OR COMPOSITION FOR DETERMINATION OF PHYSICAL STATE OR PROPERTY BY MEANS INCLUDING A CHEMICAL REACTION
| 27 |
| 436161000 |
INCLUDING CHROMATOGRAPHY
| 22 |
| 436173000 |
NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRY
| 22 |
| 436020000 |
FOOD OR DAIRY PRODUCTS
| 21 |
| 436056000 |
TRACERS OR TAGS
| 20 |
| 436514000 |
INVOLVING DIFFUSION OR MIGRATION OF ANTIGEN OR ANTIBODY
| 20 |
| 436066000 |
HEMOGLOBIN, MYOGLOBIN, OR OCCULT BLOOD
| 20 |
| 436085000 |
SYNTHETIC OR NATURAL RESIN
| 16 |
| 436064000 |
CANCER
| 16 |
| 436119000 |
SULFUR CONTAINING
| 14 |
| 436103000 |
PHOSPHORUS CONTAINING
| 13 |
| 436057000 |
INCLUDING USE OF RADIOACTIVE PROPERTIES
| 13 |
| 436025000 |
GEOCHEMICAL, GEOLOGICAL, OR GEOTHERMAL EXPLORATION
| 12 |
| 436124000 |
HALOGEN CONTAINING
| 11 |
| 436147000 |
MEASUREMENT INCLUDES TEMPERATURE CHANGE OF THE MATERIAL BEING ANALYZED (E.G., CALORIMETRY, ETC.)
| 11 |
| 436139000 |
HYDROCARBON
| 10 |
| 436034000 |
RATE OF REACTION DETERMINATION
| 10 |
| 436060000 |
LUBRICANT, GREASE, MINERAL OIL, HYDROCARBON OIL PRODUCT, OR FATS OR LIPIDS FOR OXIDATION (E.G., BREAKDOWN PRODUCTS OR CONTAMINATION, ETC.)
| 9 |
| 436055000 |
CONDITION RESPONSIVE CONTROL
| 8 |
| 436145000 |
CARBON CONTAINING
| 7 |
| 436100000 |
INORGANIC ACID OR BASE (E.G., HCL, SULFURIC ACID, ETC.)
| 7 |
| 436506000 |
FOR PREEXISTING IMMUNE COMPLEX OR AUTO-IMMUNE DISEASE
| 7 |
| 436500000 |
THYROID HORMONE TESTS (E.G., T3, T4, TBG, TSH, ETC.)
| 6 |
| 436069000 |
CLOTTING OR CLOTTING FACTOR LEVEL TESTS
| 6 |
| 436037000 |
TESTING OF CATALYST | 5 |
| 20090305425 | In-Line Localized Monitoring of Catalyst Activity in Selective Catalytic NOx Reduction Systems - Localized catalyst activity in an SCR unit for controlling emissions from a boiler, power plant, or any facility that generates NO | 12-10-2009 |
| 20110217781 | CATALYST FORMULATION FOR HYDROGENATION - A composition and method for preparation of a catalyst for the liquid phase selective hydrogenation of alkynes to alkenes with high selectivity to alkenes relative to alkanes, high alkyne conversion, and sustained catalytic activity comprising a Group VIII metal and a Group IB, Group IIB, Group IIIA, and/or Group VIIB promoter on a particulate support. | 09-08-2011 |
| 20110111508 | CONTINUOUS PROCESS FOR MAINTAINING THE ACID CONTENT OF AN IONIC LIQUID CATALYST - A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. | 05-12-2011 |
| 20110045596 | PROCESS AND INSTALLATION FOR TESTING CATALYSTS - The invention relates to a process for testing performance levels and/or changes over time of at least one catalyst CAT for a fixed-bed reactor comprising at least the following stages:
| 02-24-2011 |
| 20110183423 | PROCESS FOR CONTROLLING IONIC LIQUID CATALYST ACTIVITY BY TITRATION - A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. | 07-28-2011 |
| 436001000 |
PROCESS OR COMPOSITION FOR STERILITY OR PACKAGE INTEGRITY TEST | 5 |
| 20110275159 | CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS - A chemical indicator composition comprising a bismuth (III) compound selected from the group consisting of bismuth (III) oxide and a bismuth (III) compound comprising at least one organic group which includes 2 to 20 carbon atoms; elemental sulfur; and a compound which makes the composition alkaline when exposed to water vapor at an elevated temperature; a chemical indicator composition comprising a bismuth (III) compound; elemental sulfur; a compound which makes the composition alkaline when exposed to water vapor at an elevated temperature; and at least one acid other than any acid present in the bismuth (III) compound; a chemical indicator comprising a substrate and the composition coated on at least a portion of a major surface of the substrate; methods of making the chemical indicator; and methods of using the chemical indicator are disclosed. | 11-10-2011 |
| 20100124784 | HYDROGEN PEROXIDE AND PERACETIC ACID INDICATORS AND METHODS - The present invention provides a hydrogen peroxide indicator and a peracetic acid indicator that include a substrate on which is disposed an indicator composition that includes at least one of a select group of colorants and a transition metal salt. As a result of exposure to hydrogen peroxide and/or peracetic acid, the colorants change color, and even become colorless, thereby providing an indication of the presence of hydrogen peroxide and/or peracetic acid. | 05-20-2010 |
| 20110244577 | OXYGEN PERMEABILITY MEASURING APPARATUS AND METHOD, AND DEFECT INSPECTION APPARATUS AND METHOD - An oxygen permeability measuring apparatus for measuring an oxygen permeation rate of oxygen barrier film in a dark room is provided. A container is charged with inert gas, and sealed hermetically by use of the oxygen barrier film at least partially. A chemiluminescent compound is contained in the container, for emitting light by oxidation with the oxygen. A photon detector detects photons emitted by the chemiluminescent compound so as to determine an amount of the oxygen permeated through the oxygen barrier film. Preferably, the container includes a container body. An opening is formed in the container body, and closed hermetically by the oxygen barrier film attached thereto. The photon detector is disposed inside or outside the container. The oxygen permeation rate is equal to or less than 10 | 10-06-2011 |
| 20110136238 | OXYGEN INDICATOR - The invention relates to a dye composition comprising a dye, dye converter, binder, reducing agent, solvent and optionally basic agent. Further, the invention relates to a method for fabricating an oxygen indicator wherein a dye composition is applied over a substrate and reduced by heating, to an oxygen indicator fabricated by the method and to a package for detecting a leakage and/or variation in the oxygen content. | 06-09-2011 |
| 20110312096 | CHEMICAL INDICATOR COMPOSITIONS, INDICATORS AND METHODS - Chemical indicator compositions comprising a bismuth compound; elemental sulfur; and a compound with relatively high water solubility which makes the composition alkaline when exposed to water vapor at an elevated temperature; a chemical indicator comprising a substrate and the composition coated on at least a portion of a major surface of the substrate; and methods of making and using the chemical indicator are disclosed. | 12-22-2011 |
| 436155000 |
PYROLYSIS, COMBUSTION, OR ELEVATED TEMPERATURE CONVERSION | 5 |
| 20090081804 | Monitor and methods for characterizing airborne particulates - A dust monitor is disclosed that is suitably deployed in dusty environments and capable of providing near real-time indications of exposure to airborne particulates. The monitor includes a filter and filter assembly made of materials that do not interfere with subsequent instrumental (such as spectrometric) analysis for detecting and/or quantitating an analyte. In some disclosed embodiments, the filter is made of nylon or other material that is readily subjected to thermal destruction prior to spectrometric analysis. The dust monitor also includes a humidity correction feature that permits the filter to be made of ashable organic materials even if those materials are not highly hydrophobic. Transport devices are provided for shipment of the filter and/or filter assembly to an analytical laboratory which prevent loss of particulate matter and which facilitate an accurate analysis procedure. | 03-26-2009 |
| 20100055802 | Analysis using separation combined with chemical conversion followed by optical spectroscopy - The present invention relates to the separation, quantitative measurement, and analysis of trace species using a combination of three steps in succession. First, trace species are separated from other species that are present. Second, the trace species are chemically modified to convert them into specific species that are advantageous for the third and final step. In this last step, cavity enhanced optical detection of the converted species is performed to detect and measure the concentrations of the species of interest. Because the last step has spectroscopic resolution, the concentration of isotopologues in each converted species can be determined. Further processing can provide the ratios between pairs of isotopologues, in particular the ratio of the rare isotopologues to the most abundant isotopologue. | 03-04-2010 |
| 20080299670 | COMBUSTION TUBE AND METHOD FOR COMBUSTING A SAMPLE FOR COMBUSTION ANALYSIS - Combustion tube ( | 12-04-2008 |
| 20110244587 | QUANTIFICATION OF LUBRICANT REACTIVITY USING CONSTANT VOLUME COMBUSTION DEVICE - A method for identifying a lubricant composition that reduces the propensity for knock in an engine. The lubricant composition is mixed with a solvent to reduce the viscosity of the lubricant composition, thereby forming a lubricant-solvent mixture having a viscosity similar to or less than that of engine fuel. A sample of a lubricant-solvent mixture is then subjected to a constant volume combustion test to determine the reactivity associated with the lubricant-solvent mixture. The test is repeated for a range of lubricant-solvent ratios, and statistical methods are used to calculate the reactivity of the lubricant composition without solvent. | 10-06-2011 |
| 20110151575 | Energetic Material Detector - Energy released from energized particles is sensed. Whether the energized particles include a possible energetic material is determined based on the sensed energy. If a determination is made that the energized materials include a possible energetic material, a spectral signature of the sensed energy is determined. The spectral signature of the sensed energy is compared to one or more known spectral signatures associated with energetic materials. Whether the possible energetic material is an actual energetic material is determined based on the comparison. | 06-23-2011 |
| 436512000 |
INVOLVING ANTIBODY FRAGMENTS | 4 |
| 20110287559 | METHOD OF CHARACTERIZING GLYCANS ATTACHED TO GLYCOPROTEINS - A method of characterizing glycans attached to glycoproteins is disclosed herein. The method comprises a first step of immobilizing the glycoproteins on colloidal particles forming glycoprotein/colloidal particles. The glycans on the glycoproteins may then be characterized, for example the composition and/or structure of glycans may be characterized or the glycans attached to proteins may be identified. Characterization may be accomplished by either binding the glycoprotein/colloidal particles with one or more binding agents and assessing the aggregation of the glycoprotein/colloidal particles or by cleaving glycans from the glycoprotein/colloidal particles with a cleaving agent and analyzing the glycans. | 11-24-2011 |
| 20080299678 | Methods for characterizing glycosylation sites - The present invention provides methods for isolating and characterizing the glycosylation sites of a glycoprotein, such as a glycosylated antibody. In particular, the methods employ affinity capture, liquid chromatography, and mass spectrometry to determine, for example, the location of the glycopeptide, the heterogeneity of the glycan attached to the glycopeptide, the mass of the glycopeptide, and/or the peptide sequence. | 12-04-2008 |
| 20100221846 | SENSOR, A SENSOR ARRAY, AND A METHOD OF OPERATING A SENSOR - In an example embodiment, there is a sensor for detecting particles. The sensor comprises an electrode, a sensor active region covering the electrode and the sensor active region is sensitive-for the particles. A first switch element is operable to bring the electrode to a first electric potential when the first switch element is closed, and a second switch element is operable to bring the electrode to a second electric potential when the second switch element is closed. A detector is adapted to detect the particles based on a change of the electric properties of the sensor in an operation mode in which the electrode is brought to the first electric potential and an operation mode in which the electrode is brought to the second electric potential. | 09-02-2010 |
| 20090186423 | Method for Characterization of a Recombinant Polyclonal Protein - The present invention provides a characterization platform that can be used to assess the amount of different antibodies produced by a polyclonal cell line during production, as well as batch-to-batch consistency of the antibodies present in the polyclonal products. The structural characterization platform is based on removal of the heavy chains and separation of the light chains remaining via a chromatographic separation technique followed by mass spectrometry analysis on the intact light chain species. | 07-23-2009 |
| 436543000 |
INVOLVING PRODUCING OR TREATING ANTIGEN OR HAPTEN | 4 |
| 20100190271 | METHODS USING NOVEL CHEMILUMINESCENT LABELS - Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable, and generate chemiluminescence rapidly on demand. The compounds and conjugates are useful in assays of an analyte in a sample and in assays employing labeled specific binding pairs. | 07-29-2010 |
| 20080227222 | Method for the detection of target molecules by fluorescence polarization using peptide mimics - The inventive subject matter relates to a method of measuring non-protein hydrophobic and protein target antigens by competitive fluorescence polarization using peptide mimics as competitors. The peptide mimics used in the inventive method contain conformational epitopes not represented in the linear sequence. The method can be used in the detection of a wide range of agents including steroids, hormones, nucleic acids, proteins and infectious organisms. A method for the detection of cortisol and gamma-interferon is also contemplated in the method. Samples suitable for analysis by the inventive method include environmental samples and bodily fluids including serum and oral fluids including saliva. | 09-18-2008 |
| 20090291509 | Sensing method - To enable successive measurement of samples by using one piezoelectric sensor. An adsorption layer provided in a piezoelectric sensor is an adsorption layer in which protein and an immunoglobulin are stacked in this order from the bottom. The immunoglobulin has a property of separating from protein when coming into contact with an acid liquid, and therefore, when the immunoglobulin as the adsorption layer is brought into contact with the acid liquid after capturing a substance to be sensed, the immunoglobulin is separated from the protein. Then, the adsorption layer is again formed by the supply of a new immunoglobulin, which enables the successive measurement of samples. | 11-26-2009 |
| 20080213922 | Method And System For Identification Of Antigen - There is provided a method for the identification of antigens recognized by a given antibody. In particular the method provides for characterization of the epitope recognized by the antibody and for purification based on the physico-chemical properties of the antigen. The characterization facilitates subsequent analysis of the antigen for identification purposes. | 09-04-2008 |
| 436039000 |
DETERMINATION OF WATER | 4 |
| 20090053815 | Use of Holographic Sensors - A method of measuring the amount of an analyte in a sample, comprises (a) passing the sample through a flow channel in or on a holographic sensor, wherein the analyte interacts with and is retained by the sensor and wherein the interaction of the analyte changes an optical property of the sensor, and (b) monitoring analyte interaction, wherein the distance along the flow channel at which analyte interaction occurs or the area of the channel over which analyte interaction occurs, indicates the amount of analyte in the sample. Further, a method of detecting an analyte in a sample, comprises (a) passing the sample through a flow channel in or on a holographic sensor, wherein the analyte interacts with the sensor, thereby changing an optical property of the sensor, and wherein the flow channel defines a symbol; and (b) detecting the analyte by observing the appearance, disappearance or change in appearance of the symbol. | 02-26-2009 |
| 20100159599 | LATERAL-FLOW POROUS MEMBRANE ASSAY WITH FLOW RATE CONTROL - Various modifications to a porous substrate, such as employed in lateral flow assay devices, to regulate or modify the flow rate and/or flow path pattern of a fluid through the porous substrate is described. The lateral flow assay device has a porous substrate matrix in fluid communication with a flow-rate control zone having a number of flow-rate control devices arranged as features in or on a substrate surface or laminates thereof in a body. The flow-rate control devices may include: a density gradient, porosity gradient, ion affinity gradient, micro-channels, and combinations thereof. | 06-24-2010 |
| 20090035865 | MOISTURE SENSOR - A moisture sensor is disclosed which measures cumulative exposure to moisture. The moisture sensor comprises a matrix having a hygroscopic material, a first reagent, and a second reagent which interact only in the presence of water to produce a detectable, irreversible change in the matrix to provide a moisture indication. The moisture sensor may be incorporated with a disposable diagnostic device, whereby a method for preventing the use of such a disposable diagnostic device if exposed to excessive cumulative humidity is also disclosed. | 02-05-2009 |
| 20080220529 | SYSTEM AND METHOD FOR FERTILIZER SELECTION - A system, method and computer readable program is disclosed for facilitating the selection of a fertilizer. The basis for selecting the fertilizer includes determining the water type based on the water chemistry and taking into consideration the crop type that is to be grown. | 09-11-2008 |
| 436510000 |
IMMUNOCHEMICAL PREGNANCY DETERMINATION | 4 |
| 20100129935 | PREGNANCY TESTING METHOD - The present invention relates to a method of determining if a patient is pregnant and if the pregnancy is progressing. The method involves testing the patient a first time with a hCG home urine test, then after a select number of days, a second hCG home urine test is taken having a lower hCG sensitivity than the first. | 05-27-2010 |
| 20080299677 | NEW ASSAYS FOR PREIMPLANTATION FACTOR AND PREIMPLANTATION FACTOR PEPTIDES - The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the observation that flow cytometry using fluorescently labeled anti-lymphocyte and anti-platelet antibodies demonstrated an increase in rosette formation in the presence of PIF. It is further based on the observation that flow cytometry demonstrated that monoclonal antibody binding to CD2 decreased in the presence of PIF. The present invention further relates to PIF peptides which, when added to Jurkat cell cultures, have been observed to either (i) decrease binding of anti-CD2 antibody to Jurkat cells; (ii) increase expression of CD2 in Jurkat cells; or (iii) decrease Jurkat cell viability. In additional embodiments, the present invention provides for ELISA assays which detect PIF by determining the effect of a test sample on the binding of anti-CD2 antibody to a CD2 substrate. | 12-04-2008 |
| 20090305436 | DEVICE AND METHOD FOR DETECTION OF A PREGNANCY ASSOCIATED HORMONE - The invention provides a device ( | 12-10-2009 |
| 20080274564 | PREGNANCY AND SEX IDENTIFICATION TEST BASED ON SALIVA OR OTHER BODILY FLUIDS - A method of testing an animal for pregnancy or identifying the sex of the animal comprising the steps of first, providing a first vessel containing a liquid and having a removable surface wherein said removable surface is at least partially coated with an antibody and then introducing a bodily fluid from the female animal into said first vessel so that said bodily fluid contacts the liquid and then manipulating the first vessel so that the liquid contacts the antibody. Then, a second vessel containing a reporter hormone solution is provided and the removable surface from the first vessel is displaced to the second vessel and manipulating the second vessel so that the reporter hormone solution contacts the removable surface. Then, a third vessel containing an indicating solution which has an appearance which is related to the amount of the reporter hormone contacted is provided, and the removable surface is displaced from the second vessel to the third vessel. The third vessel is manipulated so that the indicating solution contacts the removable surface. Then, a determination is made regarding the pregnancy or sex based on the appearance of the indicating solution. | 11-06-2008 |
| 436513000 |
INVOLVING IGA, IGD, IGE, OR IGM | 3 |
| 20090075395 | MULTIPLEXED BIOMARKERS FOR MONITORING THE ALZHEIMER'S DISEASE STATE OF A SUBJECT - The present invention relates to a method for diagnosing a subject's Alzheimer's disease state. The method involves providing a database containing information relating to protein expression levels associated and not associated with Alzheimer's disease. The database includes information relating to at least a majority of the following proteins: albumin, alpha-1-antitrypsin, apolipoprotin E, apolipoprotein J, complement component 3, contactin, fibrin beta, Ig heavy chain, Ig light chain, neuronal pentraxin receptor, plasminogen, proSAAS, retinol-binding protein, transthyretin, and vitamin D binding protein. Information relating to proteins found in one or more cerebrospinal fluid samples from a subject is also provided and a database is used to analyze the information from the subject to diagnose the subject's Alzheimer's disease state. Also disclosed is a computer readable medium and a system, both useful in carrying out the present invention. | 03-19-2009 |
| 20100248393 | METHOD FOR DETERMINATION OF ANTIGEN AND ANTIBODY AGAINST THE ANTIGEN, AND DETERMINATION REAGENT FOR USE IN THE METHOD - For determining an antigen or an antibody against the antigen in a sample, a determination reagent is used which comprises an antibody capable of causing an antigen-antibody reaction with the antigen contained in the sample and an antigen capable of causing an antigen-antibody reaction with both of the antibody contained in the sample and the antibody contained in the reagent. Either one of the antigen and the antibody in the reagent is supported on a microparticle. The sample is mixed with the reagent. The antigen or the antibody in the sample can be determined based on the degree of increase or decrease in agglutination caused by the antigen-antibody reaction. It becomes possible to determine both of an antigen and an antibody against the antigen in a sample accurately using one and the same reagent. | 09-30-2010 |
| 20110256641 | Methods and Systems for Detecting Free IgE - The present disclosure provides methods, systems, and kits for detecting IgE antibodies available to bind to the Fc epsilon receptor in a biological sample from a subject receiving anti-IgE therapy. These methods, systems, and kits find use in monitoring anti-IgE therapy and determining its efficacy. | 10-20-2011 |
| 436072000 |
SILICON CONTAINING | 3 |
| 20100273266 | TARGET BIOMATERIAL DETECTING KIT AND METHOD OF DETECTING TARGET BIOMATERIAL - Provided are a target biomaterial detecting kit and a method of detecting the target biomaterial. The target biomaterial detecting kit includes a guided mode resonance filter comprising a substrate transmitting or reflecting light, a grating layer formed on the substrate, and a capture layer formed on the grating layer to capture a target biomaterial; and a nano complex comprising a nanoparticle head and a connection tail. Therefore, the wavelength peak of a reflection/transmission spectrum of light coming from the guided mode resonance filter can be largely shifted, and thus the presence and quantity of a target biomaterial can be easily detected. Moreover, although the amount of the target biomaterial is small, the target biomaterial can be reliably detected. | 10-28-2010 |
| 20090130767 | ORGANOSILANES AND SUBSTRATES COVALENTLY BONDED WITH SAME AND METHODS FOR SYNTHESIS AND USE - The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications. | 05-21-2009 |
| 20100041157 | Analysis apparatus and analysis method of chlorosilanes - The problem to be solved is to provide an analysis apparatus and analysis method of chlorosilanes capable of stably carrying out an analysis with less contamination. An analysis apparatus of chlorosilanes includes a vaporizer | 02-18-2010 |
| 436547000 |
INVOLVING PRODUCTION OR TREATMENT OF ANTIBODY | 3 |
| 20080311681 | Antibody Binding Affinity Ligands - The present application discloses a solid support material having covalently immobilized thereon an affinity ligand, said ligand comprising one or more hydrophobic functional group(s) and one or more cationic functional group(s) or one or more heteroaromatic functional group(s), wherein at least one hydrophobic functional group is separated from at least one cationic/heteroaromatic functional group by a through bond distance of from 5 Å to 20 Å, wherein said ligand has a molecular weight of from 120 Da to 5,000 Da. Typically, the affinity resin has a binding capacity larger than 5 mg monoclonal antibody per mL of affinity resin. A method for the isolation of biomolecules, such as proteins, in particular antibodies, such as monoclonal antibodies, or derivatives thereof, is also disclosed. | 12-18-2008 |
| 20080220540 | Method for purifying cancer-specific proliferating cell nuclear antigen - The method for developing an antibody that exclusively binds to csPCNA. | 09-11-2008 |
| 20090075398 | Method for Obtaining Antibodies - A method of obtaining at least one recombinant antibody with improved affinity for a selected antigen from a family of antibodies which bind the selected antigen comprising: a) obtaining a family of two or more antibodies which bind the same antigen in which the VH CDR3 amino acid sequence of each antibody in the family is the same length and greater than 60% identical at the amino acid level; b) re-pairing the VH region of an antibody obtained in step (a) with the VL region from a different antibody obtained in step (a) to produce a new recombinant antibody; and c) screening the recombinant antibody produced in step (b) and selecting said antibody if it has improved affinity for the selected antigen compared to any one of the antibodies obtained in step (a). | 03-19-2009 |
| 436517000 |
INVOLVING KINETIC MEASUREMENT OF ANTIGEN-ANTIBODY REACTION | 3 |
| 20100221847 | Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and uses thereof for biomolecular interaction analysis - Photonic crystal (PC) sensors, and sensor arrays and sensing systems incorporating PC sensors are described which have integrated fluid containment and/or fluid handling structures. The PC sensors are further integrated into a sample handling device such as a microwell plate. Sensors and sensing systems of the present disclosure are capable of high throughput sensing of analytes in fluid samples, bulk refractive index detection, and label-free detection of a range of molecules, including biomolecules and therapeutic candidates. The present disclosure also provides a commercially attractive fabrication platform for making photonic crystal sensors and systems wherein an integrated fluid containment structure and a photonic crystal structure are fabricated in a single molding or imprinting processing step amendable to high throughput processing. | 09-02-2010 |
| 20090215200 | Measurement of binding rate of a binding substance and an analyte - A method of measuring the rate of binding of a binding substance and an analyte, for example in an assay such as an immunoassay, uses an initial step of performing ultrasonication sufficient to disrupt binding between the binding substance and the analyte. After cessation of the ultrasonication, measurements are taken to determine the rate of binding at cessation of said ultrasonication or at a predetermined time thereafter The ultrasonication results in knowledge of the precise time of the start of the binding reaction which provides a better rate measurement. | 08-27-2009 |
| 20090317922 | USE OF ADDITIVES TO LOWER THE RATE OF A BINDING REACTION - A method of lowering the rate of a specific binding reaction in an assay for the detection and/or measurement of an analyte of interest is provided herein. In particular, the method includes providing a fluorescent conjugate of the analyte; a component capable of specifically binding to the analyte and its fluorescent conjugate; and a sample, which includes or is suspected to include the analyte. The method also includes allowing the specific binding component to interact simultaneously or at different times with the fluorescent conjugate of the analyte and the analyte in the sample, thereby forming a detectable complex due to the reaction between the fluorescent conjugate of the analyte and its specific binding component, wherein the reaction is performed in the presence of non-physiological amounts of at least one additive. The method further includes monitoring for the rate of change of the concentration of the detectable complex as a function of the amount of analyte in the sample. | 12-24-2009 |
| 436144000 |
HYDROGEN, PER SE | 3 |
| 20110300637 | Polyaniline Nanofiber Hydrogen Sensors - A method for sensing hydrogen includes the use of a transduction device with a sensing layer, and means for measuring a mass and/or conductivity change caused by an interaction of a gas with the sensing layer to provide a measure of an amount of hydrogen in the gas. The sensing layer includes polyaniline nanofiber material. | 12-08-2011 |
| 20090017551 | Method and device for the detection of hydrogen - The present invention relates to a device and a method for the detection of hydrogen in a gas volume by means of an exothermal catalytic recombination of hydrogen and oxygen present in the gas volume into water. The amount of energy that is released during such an exothermal catalytic recombination is measured in the form of a temperature difference and is compared with a stored limit value. When a corresponding limit value is exceeded an appropriate signal is output. | 01-15-2009 |
| 20090053822 | METHOD AND Pd/V2 O5 DEVICE FOR H2 DETECTION - Methods and Pd/V | 02-26-2009 |
| 436148000 |
MEASUREMENT INCLUDES CHANGE IN VOLUME OR PRESSURE | 3 |
| 20110171744 | DISPENSING DEVICE - Provided is a dispensing device capable of removing bubbles reliably. In this dispensing device, deaerated water is fed by a water feed pump to the inside of a pipeline up to the vicinity of the leading end of a dispensing nozzle. A water feed valve disposed near a dispensing pump is closed to establish a deaerated water space opened on the leading end side of the dispensing nozzle. The dispensing pump is activated on the space, thereby causing the dispensing nozzle to perform suction and exhaust actions. The dispensing device comprises a vacuum means connected to the space through the water feed valve thereby maintaining a vacuum state. In case the deaerated water space is cleared of the bubbles, the cleared water space is brought, by opening a change-over valve, into communication with a pipeline having a vacuum means connected thereto, thereby bringing the space into the vacuum state. | 07-14-2011 |
| 20090170209 | HYDROGEL CHEMICAL SENSOR - An apparatus and method for detecting an analyte wherein a member may respond to mechanical stress induced by a volume change of a sensitive hydrogel upon sensing an analyte and wherein the mechanical stress may be detected by a detector. | 07-02-2009 |
| 20100136706 | MOLECULE-RESPONSIVE GEL PARTICLES, METHOD OF PRODUCTION OF THE SAME, AND USE THEREOF - The invention provides molecule-responsive gel particles which change in size in response to specific molecules and a method of production of the same. A polymer gel particle with a crosslinked structure has fixed thereto a plurality of clathrate compound-forming host molecules. two or more of the plurality of host molecules clathrate different atomic groups in a target molecule so that the two or more host molecules and the target molecule can form a crosslink in the molecule-responsive gel particle. | 06-03-2010 |
| 436035000 |
USING ACTIVATED SPECIE | 2 |
| 20090068747 | APPARATUS FOR EMITTING AND DETECTING LIGHT IN A NUCLEIC ACID AMPLIFICATION REACTION - Subject of the present invention is to provide an apparatus, an instrument, and a method particularly useful in multiplex PCR applications permitting short sample measuring times of many samples combined with high sensitivity. | 03-12-2009 |
| 20110129930 | INSPECTION METHOD AND APPARATUS - In an embodiment, there is disclosed an inspection method for detecting the presence of imprintable medium on an imprint lithography template. The method includes contacting the imprint lithography template with a marker, the marker being attachable to imprintable medium that may be on the imprint lithography template, the marker being configured to interact with incident radiation when attached to the imprintable medium, directing radiation at the imprint lithography template, and measuring radiation re-directed by the imprint lithography template to attempt to detect presence of a marker that has attached to the imprintable medium, from the interaction of the marker with the incident radiation, and thus detect the presence of imprintable medium to which the marker is attached. | 06-02-2011 |
| 436070000 |
SEDIMENTATION RATE OR HEMATOCRIT | 2 |
| 20080280365 | Apparatus and Method for Determining the Volume Fractions of the Phases in a Suspension - An apparatus for determining the volume fractions of the phases in a suspension includes a body, a channel structure, which is formed in the body, and an inlet area and a blind channel, which is fluidically connected to and capable of being filled via the same. Furthermore, a drive for imparting the body with rotation, so that phase separation of the suspension in the blind channel takes place, is provided. The blind channel includes such a channel cross-section and/or such wetting properties that, when filling same via the inlet area, higher capillary forces act in a first cross-sectional area than in a second cross-sectional area, so that at first the first cross-sectional area fills in the direction from the inlet area toward the blind end of the blind channel and then the second cross-sectional area fills in the direction from the blind end toward the inlet area. | 11-13-2008 |
| 20080248582 | Diagnostic Device and Method - A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte comprises a step in which the sample is received in a vessel with at least one flexible wall. In another step, an additive and particles are added to the sample, wherein the additive substantially binds to the at least one of the stem cell, lymphocyte, and leukocyte, and the particles and wherein the particles substantially bind to the at least one of the stem cell, lymphocyte, and leukocyte, and the additive, thereby producing a cell-containing network. In a further step, the network is separated from the substantially cell-depleted portion by applying a magnetic force. | 10-09-2008 |
| 436062000 |
OXYGEN DEMAND (E.G., BOD, TOD, COD, ETC.) | 2 |
| 20090186417 | Method for Determining the Oxygen Requirement of an Aqueous Solution for a Purification Process - Method of determining the oxygen demand, TOD or COD, of an aqueous solution, in particular of waste water, for a clarification process, wherein a sample of the aqueous solution is decomposed by combustion, such that the combustion is carried out without the presence of a catalyst, at a temperature above 1150° C., in particular at 1200° C. | 07-23-2009 |
| 20110027893 | Method and apparatus for automated determining of chemical oxygen demand of a liquid sample - A method and apparatus for automated determining of the chemical oxygen demand of a liquid sample, comprising steps as follows: mixing the liquid sample with sulfuric acid; introducing a carrier gas, especially air, into the liquid sample-sulfuric acid mixture; adding an oxidizing agent to the liquid sample-sulfuric acid mixture to form a reaction mixture; heating (especially under reflux conditions) the reaction mixture at the boiling temperature of the reaction mixture for a predetermined time period; photometrically determining consumption of an oxidizing agent in the reaction mixture; and ascertaining therefrom the chemical oxygen demand of the liquid sample, wherein all steps are automatedly performed in an analytical system with the assistance of an evaluating and control unit. | 02-03-2011 |
| 436183000 |
MISCELLANEOUS | 2 |
| 20100267164 | LIQUID CELL AND PASSIVATED PROBE FOR ATOMIC FORCE MICROSCOPY AND CHEMICAL SENSING - The invention provides a liquid cell for an atomic force microscope. The liquid cell includes a liquid cell housing with an internal cavity to contain a fluid, a plurality of conductive feedthroughs traversing the liquid cell housing between the internal cavity and a dry side of the liquid cell, a cantilevered probe coupled to the liquid cell housing, and a piezoelectric drive element disposed on the cantilevered probe. The cantilevered probe is actuated when a drive voltage is applied to the piezoelectric drive element through at least one of the conductive feedthroughs. A method of imaging an object in a liquid medium and a method of sensing a target species with the liquid cell are also disclosed. | 10-21-2010 |
| 20090280574 | Apparatus for Indicating The Presence of a Controlled Substance and Method of Use - An apparatus for indicating the presence of a controlled substance is disclosed for use in medical facilities licensed to administer controlled medications to patients. The apparatus contains an indicator element selected to experience a color changing chemical reaction when mixed with a specific type of medication. A medical professional can inject a portion of any unused medication into the apparatus prior to final disposal to prove that the disposed of medication is not some other compound. | 11-12-2009 |
| 436065000 |
PREGNANCY OR OVULATION | 2 |
| 20100197026 | SOLUTION FOR DETERMINING OVULATORY PERIOD IN WOMEN FROM A TEST TUBE OF URINE - The solution covered by the invention contains 0.5 to 9.0% by mass of hydrate salt of chloride anion Cl | 08-05-2010 |
| 20110201122 | HYPERGLYCOSYLATED hCG DETECTION DEVICE - The present invention related to a pregnancy test device that can selectively detect hyperglycosylated human chorionic gonadotropin (hCG-H) in a liquid sample. The sample can be deposited on a proximal portion of the device for transport to a distal portion of the device. The device can include a release medium formed of a first material and including a detectable label thereon and a capture medium, including a capture site, in fluid communication with the release medium and formed of a second, different material. At least one of the release medium and the capture medium includes a binding member that exhibits a moderate to high affinity for hCG-H and is selectively or preferentially reactive with hCG-H. | 08-18-2011 |
| 436038000 |
PURITY OF STEAM OR CHEMICALLY INERT GAS | 1 |
| 20120028360 | Apparatus and Method for Combustion Analysing a Sample - Apparatus and method for combustion analysing a sample comprising determining incomplete combustion in a combustion analyser having a combustion chamber. A sample is supplied to the combustion chamber and combusted to produce combustion products. A target gas characteristic of incomplete combustion of the sample is detected in the combustion products by a target gas sensor. The target gas may be carbon monoxide, methane, methanal and/or methanol, among others. Whether incomplete combustion of the sample has occurred may be determined. A signal indicative of incomplete combustion is output from the target gas sensor and the combustion products can be directed to waste using a valve disposed upstream of the target gas sensor. | 02-02-2012 |
| 436182000 |
ELEMENT OR INORGANIC COMPOUND | 1 |
| 20080280375 | Arsenic-Specific Stain for Identifying Arsenic-Treated Wood - A novel reagent is used to identify arsenic-treated wood. The stain may detect arsenic extracted from wood into solution; arsenic transferred from wood to a wipe, which is then extracted into solution; or the stain may be directly applied at a predetermined location on the wood's surface. Copper preservatives are not detected by the stain and phosphate interference is minimized. The process is quick, inexpensive, and easy to use. Development of a blue color (i.e., reduction of at least some Mo (VI) to Mo (V) in molybdenum blue) indicates the presence of arsenic. | 11-13-2008 |
| 436068000 |
BLOOD GAS (E.G., OXYGEN, CARBON DIOXIDE, BLOOD, PH, ETC.) | 1 |
| 20090233372 | COMPOSITIONS, KITS AND METHODS FOR DETERMINING ETIOLOGY OF TRALI AND DETECTING PATIENTS AT RISK FOR THIS TRANSFUSION REACTION - The instant application is to compositions, kits and methods to determine if a person in need of a blood transfusion is at-risk for TRALI. The invention includes embodiments of methods for testing the priming activity of a blood component or serum or plasma from a patient sustaining TRALI or the priming status of neutrophils of a patient at risk for TRALI by exposing the neutrophils to samples or priming agents, and measuring the respiratory burst in response to an activating agent. The respiratory burst may then be compared to a pre-determined value to find if the patient has abnormally high respiratory burst or the plasma or serum samples have priming activity. The present invention also contemplates kits designed to measure respiratory burst, and compositions/reagents to be used in same. | 09-17-2009 |
