| YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM Patent applications |
| Patent application number | Title | Published |
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| 20120100128 | METHODS OF AND COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF MAMMALIAN CELLS - A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity. | 04-26-2012 |
| 20120006421 | IRRIGATION CONTROL SYSTEM - A tensiometer for use in determining matric potential of a soil includes a water inlet; a hydraulic coupler comprising a porous material for providing hydraulic coupling between water that enters the inlet and the soil; and a septum that seals water that enters the inlet against ingress of air via the porous material. | 01-12-2012 |
| 20110289632 | METHYLKETONE SYNTHASE, PRODUCTION OF METHYLKETONES IN PLANTS AND BACTERIA - Isolated genes and amino acid sequences encode methylketone synthase 2 (MKS2) enzymes from tomato plants, including, ShMKS2 and SlMKS2. When expressed recombinantly in bacteria and other host cells, the MKS2 enzymes produce methylketones of various carbon chain lengths ranging from C | 11-24-2011 |
| 20110270531 | SYSTEM FOR SELECTING PLANTS FROM AMONG A POPULATION OF PLANTS - Provided is a system ( | 11-03-2011 |
| 20110251290 | TREATMENT OF HEPATIC ENCEPHALOPATHY AND LIVER CIRRHOSIS - The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or both, of liver cirrhosis. | 10-13-2011 |
| 20110217730 | SYSTEMS AND METHODS FOR ANALYZING AND MANIPULATING BIOLOGICAL SAMPLES - A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell. | 09-08-2011 |
| 20110212561 | III-V SEMICONDUCTOR CORE-HETEROSHELL NANOCRYSTALS - Provided is a core/multishell semiconductor nanocrystal including a core and multiple shells, which exhibits a type-I band offset and high photoluminescence quantum yield providing a bright tunable emission covering the visible range from about 400 nm to NIR over 1600 nm. | 09-01-2011 |
| 20110207678 | CD44 POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, ANTIBODIES DIRECTED THEREAGAINST AND METHOD OF USING SAME FOR DIAGNOSING AND TREATING INFLAMMATORY DISEASES - An isolated polypeptide is provided. The isolated polypeptide comprising an antigen recognition domain capable of specifically binding a CD44 polypeptide as set forth in SEQ ID NO: 2 and incapable of binding a CD44 polypeptide selected from the group consisting of: SEQ ID NO: 4 or 6. | 08-25-2011 |
| 20110190195 | MULTI-COMPONENT ANTIOXIDANT COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THEIR USE FOR REDUCING OR PREVENTING OXIDATIVE STRESS - An antioxidant compound is disclosed. The compound is characterized by (a) a peptide including at least three amino acid residues of which at least two are cysteine residues, each having a readily oxidizable sulfhydryl group for effecting antioxidation; and at least two peptide bonds, each being cleavable by at least one intracellular peptidase; and (b) a first hydrophobic or non-charged moiety being attached to an amino terminal of the peptide via a first bond and a second hydrophobic or non-charged moiety being attached to a carboxy terminal of the peptide via a second bond, the first hydrophobic or non-charged moiety and the second hydrophobic or non-charged moiety are selected so as to provide the antioxidant compound with membrane miscibility properties for permitting the antioxidant compound to cross cellular membranes; wherein cleavage of the at least two peptide bonds by the at least one intracellular peptidase results in generation of a plurality of antioxidant species, each including one of the cysteine residues having the readily oxidizable sulfhydryl group and which is also active in effecting antioxidation, thereby providing for a plurality of different antioxidant species acting in synergy in exerting antioxidation. | 08-04-2011 |
| 20110177102 | TARGETED DOUBLE STRANDED RNA MEDIATED CELL KILLING - A method of killing a specific target cell/tissue is disclosed. The method comprises exposing the specific target cell/tissue to a composition-of-matter which comprises a double stranded RNA molecule associated with a targeting moiety selected capable of targeting to the specific target cell/tissue, thereby killing the specific target cell/tissue. | 07-21-2011 |
| 20110135734 | Method For the Preparation of Nanoparticles From Nanoemulsions - The invention relates to a method for the production of nanoparticles from oil-in-water nanoemulsions, in which the nanoemulsion is prepared by phase inversion techniques. The phase inversion may be achieved by using a constant temperature, where the inversion occurs by continuous addition of water or by varying the temperature involving heating and rapid cooling. | 06-09-2011 |
| 20110092584 | THERAPEUTIC USE OF QUINONOID DERIVATIVES OF CANNABINOIDS - The present invention relates to cannabinoic quinone compounds, and especially to their medical use. In particular five cannabinoic quinones, designated HU-331, HU-336, HU-345, HU-395 and HU-396 are herein described as active agents in pharmaceutical compositions. Said compounds and compositions thereof are intended for the treatment of inflammatory, infectious, auto-immune and particularly hyperproliferative disorders. Thus, the compounds of the invention may be used as anti-tumor agents, or for the treatment of cancer. Furthermore, three of these compounds, HU-345, HU-395 and HU-396, are novel cannabinoic quinones and thus are also claimed herein. | 04-21-2011 |
| 20110085952 | SCRUBBER FOR REMOVING HEAVY METALS FROM GASES - A wet scrubber for absorbing a heavy metal from a gas stream, a liquor for said wet scrubber, and a power-plant comprising said wet scrubber are described. The wet scrubber has a liquor containing an oxidizer in ionic liquid. Optionally, the oxidizer has, in pure state, high vapor pressure, and in the ionic liquid, the oxidizer forms a complex that has a much lower vapor pressure. In a preferred embodiment, the liquor is substantially free of any ligand that binds to the metal to be absorbed by the liquor. | 04-14-2011 |
| 20110043604 | METHOD AND SYSTEM FOR FORMING A PANORAMIC IMAGE OF A SCENE HAVING MINIMAL ASPECT DISTORTION - A panoramic image is generated from a sequence of input frames captured by a camera that translates relative to a scene having at least two points at different distances from the camera. A processor ( | 02-24-2011 |
| 20110039791 | ACETYLCHOLINESTERASE (ACHE)-DERIVED PEPTIDE AS AN INDUCER OF GRANULOCYTOPOIESIS, USES AND METHODS THEREOF - The present invention describes the use of an AChE-R-derived peptide, also known as ARP, as an inducer of hemopoietic cell differentiation and expansion, specifically for the granulocytic population. In addition, the use of ARP as an inducer of thrombopoietin and pro-inflammatory cytokines is also presented. ARP may further be used in the pre-transplant priming of hematopoietic stem cells. Other uses and methods utilizing ARP are also described herein. | 02-17-2011 |
| 20110027351 | LIPOSOMAL FORMULATIONS COMPRISING AN AMPHIPATHIC WEAK BASE LIKE TEMPAMINE FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS - Provided is the use of an amphipathic weak base having defined characteristics for the preparation of a pharmaceutical formulation for the treatment or prevention of neurodegenerative conditions. The amphipathic weak base can be encapsulated in a liposome. Also provided are pharmaceutical formulations and methods of use thereof for the treatment or prevention of neurodegenerative conditions. A specific and amphipathic weak base is tempamine (TMN). Further, tempamine can be loaded in sterically stabilized liposomes (SSL-TMN). | 02-03-2011 |
| 20110008314 | METHODS OF AND COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF MAMMALIAN CELLS - A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity. | 01-13-2011 |
| 20110005697 | PROCESS AND COMPOSITION FOR PREPARING A LIGNOCELLULOSE-BASED PRODUCT, AND THE PRODUCT OBTAINED BY THE PROCESS - A process for the manufacture of a lignocellulose product, the process comprising the step of mixing in a reaction medium (i) a phenolic polymer being substituted with a phenolic hydroxy group; (ii) a lignocellulose containing material having immobilized to a cellulosic fraction thereof a fusion polypeptide, the fusion polypeptide including an enzyme being capable of catalyzing the oxidation of phenolic groups and a cellulose binding peptide; and (iii) an oxidizing agent. A composition of matter for use in the process and a lignocellulose product obtainable by the process are also disclosed. | 01-13-2011 |
| 20100305333 | LIPID CONJUGATED CYCLIC CARBONATE DERIVATIVES, THEIR SYNTHESIS, AND USES - The present disclosure provides processes for the preparation of lipid conjugated cyclic carbonate derivatives. More specifically, the present disclosure is based on the finding that reacting lipids, such as, ceramides, with N,N′-disuccinimidyl derivative, resulted in the formation of, isolatable, substituted cyclic [1,3]-dioxan-2-one and [1,3]-dioxan-2-thione compounds. These isolatable cyclic substituted compounds and derivatives thereof may be used for various applications, such as in vaccination. | 12-02-2010 |
| 20100297724 | METAL ENTRAPPED COMPOUNDS - The present invention provides a composite comprising at least one hydrophobic organic compound and a matrix of at least one metal; wherein said at least one hydrophobic compound is entrapped within said matrix, compositions comprising at least one composite and methods of its preparation. | 11-25-2010 |
| 20100284914 | Novel Amine-Borane Compounds and Uses Thereof - Novel families of amine-borane compounds, including fluorinated aminoboranes, novel bis-aminoboranes and aminoboranes having saturated and unsaturated ling alkyl chains are provided. Processes of preparing, pharmaceutical compositions and methods utilizing these novel compounds are also provided. Radiolabeled aminoboranes and uses thereof in radioimaging (e.g., PET) and radiotherapy are further provided. | 11-11-2010 |
| 20100279381 | Acetylcholinesterase (AChE) variants of the N-terminus - A novel form of acetylcholinesterase (AChE) is provided, N-AChE, which bears a transmembrane domain. Exons encoding this novel form, the peptide comprising, the transmembrane domain, as well as antibodies recognizing the same are also provided. N-AChE expression in the hippocampus is correlated with Alzheimer's disease. Secreted forms of AChE are also provided, and methods of producing AChE protein are, also described. | 11-04-2010 |
| 20100241020 | Real-time methods and systems for mapping a target region in the brain during surgery - A real-time method and system to accurately demarcate sub-territories of the subthalamic nucleus area in the brain during surgery, based on microelectrode recordings and a Hidden Markov Model. Root mean square and power spectral density of the microelectrode recordings are used to train and test Hidden Markov Model in identifying the dorsolateral oscillatory region and non-oscillatory sub-territories within the subthalamic nucleus. After the dorsolateral oscillatory region in the subthalamic nucleus is mapped, the microelectrodes are removed, and a macroelectrode is inserted in the mapped dorsolateral oscillatory region for producing deep brain simulation for treatment of Parkinson's disease. | 09-23-2010 |
| 20100232729 | METHOD AND SYSTEM FOR SHIFT-MAP IMAGE EDITING - Natural looking output images are computed from input images based on given user constraints. Pixels in the output images are assigned a shift such that the respective output pixel value is derived from the value of the input pixel whose location is related to that of the output pixel by the shift, at least one shift being non-zero. The shift is determined by an optimization process adapted to minimize a cost function that includes a data term on the shifts of single pixels and a smoothness term on the shifts of pixel pairs. The output image is computed by applying the optimized shift-map between the input and output pixels. The data term can include shift constraints that limit the location in the output images of selected input pixels, and saliency constraints, indicating a preference that selected pixels in the input images will or will not appear in the output image. | 09-16-2010 |
| 20100222438 | METHODS COMPOSITIONS AND ARTICLE OF MANUFACTURE FOR MODULATING BONE GROWTH - Novel methods and pharmaceutical compositions suitable for modulating bone growth and remodeling, preventing bone diseases, inducing bone growth or repair by cannabinoid receptor-mediated effects on bone cells is disclosed. Methods of identifying bone growth modulating agents are also disclosed. | 09-02-2010 |
| 20100212050 | PLANTS OVER-EXPRESSING PME - The present invention relates to compositions and methods for over-expressing pectin methylesterases (PMEs), particularly type 1 PMEs (PME1s), in plants while maintaining growth as compated to the wild type. The plants of the invention have improved properties compared to the wild type, particularly improved resistance to salinity. | 08-19-2010 |
| 20100160443 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS - The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention additionally relates to a pharmaceutical composition comprising compounds for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. A method for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration is also provided. | 06-24-2010 |
| 20100159012 | Conjugates of Therapeutically Active Compounds - The present invention discloses modified polymer conjugates of a polymer and a drug having reduced toxicity relative to the unmodified parent compound while retaining substantially the same degree of therapeutic activity as of the unmodified parent compound. | 06-24-2010 |
| 20100152238 | NOVEL QUINONOID DERIVATIVES OF CANNABINOIDS AND THEIR USE IN THE TREATMENT OF MALIGNANCIES - Novel cannabinoid-derived quinone derivatives (quinonoid derivatives) having a substituted hydroxyl group, pharmaceutical compositions comprising same and uses thereof as anti-proliferative agents, are provided. | 06-17-2010 |
| 20100136084 | RESPONSIVE POLYMERIC SYSTEM - A novel environmentally responsive polymeric system is provided for biomedical applications, comprising silicon-containing reactive groups which undergo a hydrolysis-condensation reaction at a predetermined body site and thereby change rheological and mechanical properties of the polymeric system. The polymeric system is useful, for example, as a sealant, as a matrix for drug delivery, in the prevention of post-surgical adhesions, and in gene therapy. | 06-03-2010 |
| 20100113335 | COMPOSITIONS AND METHODS FOR TREATEMENT OF CANCER - The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle disease Virus (NDV) is specifically characterized in terms of biological activities. The present invention further discloses treatment of cancer by application of a clonal NDV strain to tumors. According to an alternative preferred embodiment the use of at least one isolated viral protein or subunit or analog thereof, or an isolated polynucleotide encoding same, is used in the treatment of cancer. | 05-06-2010 |
| 20100104607 | ANTI-BACTERIAL PEPTIDES AND METHODS OF TREATING DISEASES USING SAME - Isolated peptides comprising no more than ten amino acids and having anti-bacterial properties are disclosed. In one embodiment the peptides have a consensus amino acid sequence X | 04-29-2010 |
| 20100098749 | METHODS FOR JOINT LUBRICATION AND CARTILAGE WEAR PREVENTION MAKING USE OF GLYCEROPHOSPHOLIPIDS - The present invention concerns methods of joint lubrication and/or prevention of cartilage wear making use of liposomes having membranes with at least one phospholipid (PL) of the group consisting of a glycerophospholipid (GPL) having two, being the same or different, C | 04-22-2010 |
| 20100085372 | Colorization method and apparatus - A method for colorization of images is presented. The method comprises the following steps: Displaying an image ( | 04-08-2010 |
| 20100078328 | Electrochemical co-deposition of sol-gel films - A method for the co-deposition of sol-gel and one or more additives selected from a great variety of agents including monomers, oligomers, polymers, metals and others is provided. The method affords continuous films of high stability and precision. Also provided is a surface coated with a film of sol-gel and at least one additive electrodeposited according to the presently described methods. | 04-01-2010 |
| 20100072396 | CONCURRENT MONITORING OF A PLURALITY OF SAMPLES BY AN ARRAY OF BIOSENSING ELEMENTS - A system and method are presented for monitoring detectable responses from multiple biosensing elements while in contact with multiple samples located in an array. The system ( | 03-25-2010 |
| 20100056827 | COMPOUNDS USEFUL FOR TREATING BIPOLAR DISORDERS - The invention relates to the use of valnoctamide (VCD) for the treatment of bipolar disorder and in particular for the treatment of the manic phase of the bipolar disorder. | 03-04-2010 |
| 20100022631 | Treatment of hepatic encephalopathy and liver cirrhosis - The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or both, of liver cirrhosis. | 01-28-2010 |
| 20100015213 | Compositions and Methods Using Same for Delivering Agents Into a Target Organ Protected by a Blood Barrier - A method of delivering a pharmaceutical agent into a target organ protected by a blood barrier is provided. The method comprising administering to a subject in need thereof an amount of liposomes which comprise the pharmaceutical agent, the amount and the liposomes are selected such that the liposomes accumulate in cells of an immune system of the subject to thereby generate liposome loaded immune cells, the liposome loaded immune cells become activated and cross the blood barrier, and an effective amount of the pharmaceutical agent is released from the liposomes in the target organ of the subject. | 01-21-2010 |
| 20100004244 | USE OF CB2 RECEPTOR AGONISTS FOR PROMOTING NEUROGENESIS - The present invention relates to ligands of the peripheral cannabinoid receptor CB | 01-07-2010 |
| 20090317358 | CHIMERIC PROTEINS WITH CELL-TARGETING SPECIFICITY AND APOPTOSIS-INDUCING ACTIVITIES - The present invention relates to chimeric proteins with cell-targeting specificity and apoptosis-inducing activities. In particular, the invention is illustrated by a recombinant chimeric protein between human interleukin-2 (IL2) and Bax. The chimeric protein specifically targets IL2 receptor (IL2R)-expressing cells and induces cell-specific apoptosis. | 12-24-2009 |
| 20090304587 | BIODEGRADABLE COMPOSITE FOR INTERNAL LOCAL RADIOTHERAPY - The present invention discloses composites which generally comprise a polymeric matrix and a hydrophobic organic compound which is associated with a radioisotope. The composites are biocompatible and biodegradable hydrogels suitable for use in internal local radiation therapy | 12-10-2009 |
| 20090302226 | SOLID-STATE NEUTRON AND ALPHA PARTICLES DETECTOR AND METHODS FOR MANUFACTURING AND USE THEREOF - A solid-state detector for detection of neutron and alpha particles detector and methods for manufacturing and use thereof are described. The detector has an active region formed of a polycrystalline semiconductor compound comprising a particulate semiconductor material sensitive to neutron and alpha particles radiation imbedded in a binder. The particulate semiconductor material contains at least one element sensitive to neutron and alpha particles radiation, selected from a group including 10Boron, 6Lithium, 113Cadmium, 157Gadolinium and 199Mercury. The semiconductor compound is sandwiched between an electrode assembly configured to detect the neutron and alpha particles interacting with the bulk of the active region. The binder can be either an organic polymer binder or inorganic binder. The organic polymer binder comprises at least one polymer that can be selected from the group comprising polystyrene, polypropylene, Humiseal™ and Nylon-6. The inorganic binder can be selected from B2O3, PbO/B2O3/, Bi2O3/PbO, Borax glass, Bismuth Borate glass and Boron Oxide based glass. | 12-10-2009 |
| 20090287194 | DEVICE FOR IRRADIATING AN INTERNAL BODY SURFACE - The invention provides a device and method for illuminating a body surface. A light source is optically coupled to the proximal end of a light guide and a light scatterer is optically coupled to the distal end of the light guide. The device includes a deployment mechanism that is configured to bring the light scatterer from a small caliber configuration in which the light scatterer is delivered to the body surface to a large caliber configuration in which the light scatterer irradiates the body surface. The invention may be used, for example, irradiate the periadventitial surface of an aneurysmal blood vessel. | 11-19-2009 |
| 20090281045 | Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders - A method for the treatment or prevention of pain and/or a headache disorder using a derivative of a valproic acid amide or a 2-valproenic acid amide, as well as pharmaceutical compositions comprising these derivatives or compounds. | 11-12-2009 |
| 20090246287 | ANTI-ALLERGY COMPOSITIONS - The present invention relates to particles of glucans, particularly oxidized cellulosed for use in medicine. The invention further discloses pharmaceutical compositions for the treatment and/or prophylaxis of diseases or disorders associated with or mediated by allergens. | 10-01-2009 |
| 20090221681 | NUCLEIC ACID CONSTRUCTS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME FOR TREATING CANCER - A nucleic acid construct that includes (i) a first nucleic acid sequence encoding TNF alpha; (ii) a second nucleic acid sequence encoding a Diphtheria toxin; and (iii) at least one additional nucleic acid sequence of a cancer specific promoter. The TNF alpha and Diphtheria toxin encoding sequences are under an expression control of the cancer specific promoter. Also provided are construct systems and methods and uses of same. | 09-03-2009 |
| 20090214649 | Scaffolds with oxygen carriers, and their use in tissue regeneration - Provided are fibrin or silk matrices comprising an oxygen carrier, and matrices, which comprise an oxygen carrier and mesenchymal stem cells. Also provided are methods of generating and using same for ex vivo or in vivo tissue regeneration and/or repair such as for treating a non-union bone fracture and a condition requiring spinal fusion. | 08-27-2009 |
| 20090209504 | Use of Digitalis-Like Compounds in the Treatment of Affective Disorders - Use of digitalis-like compounds such as 19-norbufalin derivatives in the treatment of affective disorders such as anxiety, depression and bipolar disorders is disclosed. | 08-20-2009 |
| 20090182048 | Compounds Useful For Treating Neurological Disorders - The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention additionally relates to a pharmaceutical composition comprising compounds for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. A method for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration is also provided. | 07-16-2009 |
| 20090169526 | BMP-6 ESTROGEN RESPONSIVE ELEMENT AND METHODS OF USE THEREOF - This invention is directed to a BMP-6 ERE nucleic acid sequence, vectors, cells and compositions comprising same. This invention also provides methods for identification of estrogen agonists, antagonists and therapeutic applications of same. This invention also provides methods of treating conditions, which are associated with estrogen insufficiency or with lack of response to external estrogen or agonists thereof utilizing sequences, vectors, cells and/or compositions described herein. | 07-02-2009 |
| 20090169520 | Compounds, Pharmaceutical Compositions and Therapeutic Methods of Preventing and Treating Diseases and Disorders Associated With Amyloid Fibril Formation - Compounds, pharmaceutical compositions and methods for prevention and/or reversal of amyloid fibril formation and treating amyloid-related disorders are provided. Also provided a method of limiting and/or reducing inflammation. | 07-02-2009 |
| 20090165171 | Transgenic Plants Exhibiting Increased Tolerance to Stress and Methods of Generating Same - Methods of increasing tolerance of a plant to stress are provided. According to an exemplary aspect a method of increasing tolerance of a plant to a biotic stress is provided. The method comprising expressing within the plant an exogenous thereby increasing the tolerance of the plant to the biotic stress. Also provided are nucleic acid constructs and transgenic plants comprising same. | 06-25-2009 |
| 20090156743 | METHOD FOR NUCLEATING POLYMERS - The present invention discloses a nucleating microemulsion comprising nanovehicles, each comprising an amphiphilic shell surrounding a nucleating agent. The microemulsion is suitable for the delivery of the nucleating agents into a thermoplastic polymer, thereby allowing crystallization of the polymer. | 06-18-2009 |
| 20090155345 | METHODS FOR AFFECTING LIPOSOME COMPOSITION ULTRASOUND IRRADIATION - The present invention provides methods for loading of agents and substances into per-formed liposomes, preferably a suspension of pre-formed liposomes as well as to methods for the controlled quantum (step-wise) release of agents and substances from liposomes. One of the principle features of the methods of the invention is to expose the liposomes to ultrasound irradiation having predefined parameters, resulting in an increase in permeability of the liposomes, thereby permitting, respectively, the loading and/or release of agents and substances into and/or from the liposomes. | 06-18-2009 |
| 20090114599 | Removal Of Organic Pollutants From Contaminated Water - There is provided a method or a system for purification of water from neutral and anionic organic contaminants using either a mixture of a complex of an organic cation adsorbed on clay as a micelle, and a granular material or a complex of an organic cation adsorbed on clay as a micelle. There is also provided a column accommodating the mixture of a complex of an organic cation adsorbed on clay as a micelle, and a granular material. | 05-07-2009 |
| 20090104202 | CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases - An isolated polypeptide is provided. The isolated polypeptide comprising an antigen recognition domain capable of specifically binding a CD44 polypeptide as set forth in SEQ ID NO: 2 and incapable of binding a CD44 polypeptide selected from the group consisting of: SEQ ID NO: 4 or 6. | 04-23-2009 |
| 20090093053 | CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases - An isolated polypeptide is provided. The isolated polypeptide comprising an antigen recognition domain capable of specifically binding a CD44 polypeptide as set forth in SEQ ID NO: 2 and incapable of binding a CD44 polypeptide selected from the group consisting of: SEQ ID NO: 4 or 6. | 04-09-2009 |
| 20090082549 | FcE-PE chimeric protein for targeted treatment of allergy responses a method for its production and pharmaceutical compositions containing the same - The present invention generally relates to a new approach for the therapy of allergic responses, based on targeted elimination of cells expressing the FcεRI receptor by a chimeric cytotoxin FC | 03-26-2009 |
| 20090035349 | Composite scaffolds and methods using same for generating complex tissue grafts - A composite scaffold for engineering a heterogeneous tissue is provided. The composite scaffold includes: (a) a first scaffold being capable of supporting formation of a first tissue type thereupon; and (b) a second scaffold being capable of supporting formation of a second tissue type thereupon; wherein the first scaffold and the second scaffold are arranged with respect to each other such that when the first scaffold supports the first tissue type and the second scaffold supports the second tissue type, a distance between any cell of the second tissue type and the first tissue type does not exceed 200 μm. | 02-05-2009 |
| 20090029407 | Systems And Methods For Analyzing And Manipulating Biological Samples - A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell. | 01-29-2009 |
| 20090011009 | Microspheres comprising nanocapsules containing a lipophilic drug - The present invention provides microspheres comprising a plurality of nanocapsules accommodated in a gel forming polymer, the plurality of nanocapsules comprising an oil core carrying a non hydrophilic active agent and a shell of polymeric coating. The invention also provides a method for preparing the microspheres of the invention, pharmaceutical compositions comprising the same as well as methods of use of the microspheres, specifically, in therapeutic, cosmetic and diagnostic applications. | 01-08-2009 |
| 20090005331 | AChE antisense oligonucleotide as an anti-inflammatory agent - Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described. | 01-01-2009 |
| 20080306014 | Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial - The present invention provides agents which are capable of regulating the function of a micro-RNA component which can be used to regulate an AChE-associated biological pathway. In addition, the present invention provides methods and pharmaceutical compositions for the treatment of various pathologies related to AChE-associated biological pathways such as apoptosis, aberrant cholinergic signaling, abnormal hematopoietic proliferation and/or differentiation, cellular stress, exposure to inflammatory response-inducing agents, and/or exposure to organophosphates or other AChE inhibitors. | 12-11-2008 |
| 20080262321 | Early Detection of Harmful Agents: Method, System and Kit - A portable system for detecting agents present in a sample is disclosed. The system comprises a sensing device, having a substrate formed with a plurality of reaction chambers and a plurality of channels interconnecting at least a portion of the plurality of reaction chambers, wherein at least a portion of the plurality of reaction chambers comprises a sensor, capable of generating a detectable signal when exposed to the agents. The system further comprises a detector, which receives signals from the sensing device and provides an image of sensors generating the optical signals. The portable system is connected to a communication network via a communication unit. | 10-23-2008 |
| 20080213353 | Method for preparing liposome formulations with a predefined release profile - The present invention provides a novel tool for designing a release profile of an active agent from a liposome in to which it is loaded. According to the invention, a method is provided for preparing a liposomal formulation for delivery of an active agent to a target, the release of said active agent from the liposome being designed to have a release profile in which the release is sustained for a time period to achieve an optimal effect of the active agent at said target, the method comprising preparing a liposomal formulation, wherein the liposome is loaded with said active agent and with a selected counter ion, the counter ion and the active agent interacting together to aggregate and/or to form a precipitate within the liposome, the counter ion being selected such that the release of the active agent from the liposome has said release profile. | 09-04-2008 |
| 20080210122 | Ink for Ceramic Surfaces - The present invention concerns ink for printing on ceramic surfaces such as glass, which contains glass frits for silica nanoparticles and optionally a pigment, and is suitable for ink jet printing. | 09-04-2008 |
