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Yissum Research Development Company of the Hebrew Univeristy of Jerusalem Ltd

Yissum Research Development Company of the Hebrew Univeristy of Jerusalem Ltd Patent applications
Patent application numberTitlePublished
20110076282METHODS OF KILLING CELLS AND USE OF SAME IN PREVENTION AND TREATMENT OF CANCER - A method of killing a cell having a mutation in an Adenomatous polyposis coli (APC) gene is disclosed. The method comprises contacting the cell with an inhibitor of Casein kinase I (CKI), the CKI being selected from the group consisting of CKI-alpha and CKI-delta and CKI-epsilon, thereby killing the cell. The method may be used for treating cancers. Pharmaceutical compositions for treatment of cancers are also disclosed.03-31-2011