20150198528 | ASSAY DETECTION SYSTEM - An assay system including reagents and devices for conducting rapid, high sensitivity analyte assays, including multiplexed assays, is described. The reagents and devices are adapted for performing time-resolved signal detection with low background due to non-specific binding. Also described are apparatus for use in measuring a luminescent property of a sample. The apparatus can use light emitting diodes for emitting radiation to excite the sample, under the control of a control signal. A signal generator generates the control signal for modulating the intensity of the emitted radiation. The control signal has a first component at a first frequency with a period that is less than, or of the same order as, an expected characteristic time constant of the luminescent property. The control signal has a second component at a second frequency with a period that is greater than the expected characteristic time constant of the luminescent property. A photosensor receives the radiation luminesced from the sample as a result of the excitation and detector circuitry generates a detection signal representing an intensity of the received radiation, and demodulates the detection signal to produce a signal representing the luminescent property of the sample. | 07-16-2015 |