WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) Patent applications |
Patent application number | Title | Published |
20140127287 | LIPOSOME-ENCAPSULATED HYDROGELS FOR USE IN A DRUG DELIVERY SYSTEM - Drug delivery systems including a lipogel are disclosed. The lipogels allow for high drug loading and sustained release of drug molecules. Also disclosed are methods of making the drug delivery systems including lipogels. | 05-08-2014 |
20130306907 | DICARBOXYLATE GEMINI SURFACTANT THAT FORMS A LYOTROPIC LIQUID CRYSTAL - Aliphatic dicarboxylate Gemini surfactants and lyotropic liquid crystal compositions formed thereby are disclosed. The Gemini surfactants are capable of robustly forming Q phase morphologies over broad ranges of temperature and concentration. | 11-21-2013 |
20130130232 | SELF-LOADING MICROFLUIDIC DEVICE AND METHODS OF USE - Microfluidic devices and methods for conducting chemical assays and biological assays using microfluidic devices are disclosed. The microfluidic devices do not require external connections, tethers, tubing, valves and actuators. The microfluidic devices are useful in methods for analyzing a wide variety of chemical and biological assays such as, for example, molecule-molecule interactions, enzyme-substrate interactions, molecule identification, minimum inhibitory concentrations, therapeutically effective amounts, and toxic amounts. | 05-23-2013 |
20100185047 | Methods and Compositions for Testing and Breeding Cattle for Improved Fertility and Embryonic Survival - Disclosed are arrays of nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods using SNPs on genes of the bovine interferon tau signaling pathway for improved bovine fertilization rate, or embryo survival, or both. | 07-22-2010 |
20090299130 | METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIAL - Single nucleotide polymorphic site at position 11646 of the bovine FGF2 gene is associated with improved fertilization rate and/or improved embryo survival rate, as well as improved milk production. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. | 12-03-2009 |
20080268438 | MODEL SYSTEM FOR IDENTIFYING ANTI-CANCER AGENTS - A model system for screening and identification of compounds that interfere with Gli2 dependent tumorigenesis and provide potential use as anticancer agents is provided. In particular, the invention includes a Gli2 protein having an S662A point mutation that interferes with binding by the ubiquitin-ligase β-TrCP. The mutation inhibits Gli2 degradation by the ubiquitin pathway. Gli2 stability and half-life are increased in the host cell resulting in an increase in Gli2-dependent transcription and concomitant neoplasia and tumorigenesis. Expression of the Gli2 mutant allows for the high throughput screening of compounds that interfere with the tumorigenesis thereby identifying anticancer agents. | 10-30-2008 |