| WAKO PURE CHEMICAL INDUSTRIES, LTD. Patent applications |
| Patent application number | Title | Published |
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| 20120009594 | METHOD FOR MEASURING BETA-GLUCAN, AND BETA-GLUCAN-BINDING PROTEIN FOR USE IN THE METHOD - Disclosed are a method for measuring βG comprising the steps of bringing a sample into contact with a βG-binding protein 1 and a βG-binding protein 2, each comprising an amino acid sequence which is identical or substantially identical to an amino acid sequence shown in any one of SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, SEQ ID NO:10, SEQ ID NO:14, SEQ ID NO:16, SEQ ID NO:18, or SEQ ID NO:20, and having the β-glucan binding activity, to form a complex of the βG-binding protein 1, βG in the sample and the βG-binding protein 2, measuring quantity of the complex, and determining βG concentration in the sample based on the quantity of the complex; a reagent and a kit for use in said method; a novel βG-binding protein; a nucleic acid molecule encoding the βG-binding protein; and a method for producing the aforementioned βG-binding protein. | 01-12-2012 |
| 20120000485 | CLEANING AGENT FOR SUBSTRATE AND CLEANING METHOD - The present invention provides a cleaning agent for a substrate and a cleaning method thereof, which can effectively remove fine particles (particles) present on a surface of substrate or impurities derived from various kinds of metals (metallic impurities), without causing roughness surface of a substrate, in particular, a semiconductor substrate, and without causing corrosion or oxidation of metal wirings, in particular, copper wirings, provided on a surface of substrate, and can further remove at the same time a carbon defect present on a surface of substrate, without removing a metal corrosion inhibitor—Cu film, in particular, a Cu-BTA film. | 01-05-2012 |
| 20110259746 | Electrode for dielectrophoretic apparatus, dielectrophoretic apparatus, method for manufacturing the same, and method for separating substances using the electrode or dielectrophoretic apparatus - To provide an electrode for a dielectrophoretic apparatus in which a background detected by reflecting an excited light on an electrode present under the substance (molecule) is reduced and an S/N ratio is enhanced. Also, there is provided an dielectrophoretic apparatus, in an apparatus in which a liquid containing substances to be separated is present in a non-uniform electric field formed by a dielectrophoretic electrode, and separation is carried out by a dielectrophoretic force exerting on the substances, wherein the collecting ability of substances is enhanced. The present invention is characterized in that a vacant space is provided in an electrode whereby substances subjected to influence by a negative dielectrophoretic force can be concentrated in said vacant space of an electrode, or above or below portion of the space. | 10-27-2011 |
| 20110233048 | PHOTOBASE GENERATOR - There is intended to provide the novel compounds which generate a base easily when irradiated with long wavelength light (active energy rays), a photobase generator containing the compounds and a photobase generation method, and the present invention relates to the compounds represented by the general formula [1], a photobase generator containing the compounds and a photobase generation method: | 09-29-2011 |
| 20110230053 | ETCHING AGENT, ETCHING METHOD AND LIQUID FOR PREPARING ETCHING AGENT - The present invention is directed to provide an etching agent for a semiconductor substrate, which is capable of etching a titanium (Ti)-based metal film or a tungsten (W)-based metal film on a semiconductor substrate and an etching method using relevant etching agent, and relates to a liquid for preparing the etching agent for a semiconductor substrate composed of a solution comprising (A) hydrogen peroxide, (B) a phosphonic acid chelating agent having a hydroxyl group, (C) a basic compound, and (D-1) a copper anticorrosive and/or (D-2) 0.01 to 3% by weight of two or more kinds of anion species other than phosphonic acid chelating agents having a hydroxyl group, in which anion species have no oxidizing power, an etching method characterized by etching a titanium (Ti)-based metal film or a tungsten (W)-based metal film on a semiconductor substrate using relevant etching agent for a semiconductor substrate, further, a solution comprising (B) a phosphonic acid chelating agent having a hydroxyl group, (C) a basic compound, and (D-1) a copper anticorrosive and/or (D-2) anion species other than phosphonic acid chelating agents having a hydroxyl group, in which anion species have no oxidizing power. | 09-22-2011 |
| 20110201845 | PROCESS FOR PRODUCING TRIPHENYLENE COMPOUND AND CRYSTAL OBTAINED BY THE PROCESS - An object of the present invention is to provide a process for producing high-purity hydroxytriphenylenes in which not only inexpensive raw materials can be used but also no complicated steps of deprotection such as dealkylation, and reduction and the like are necessary, and which is thereby advantageous in industrial production. Also there is provided a novel crystal of 2,3,6,7,10,11-hexahydroxytriphenylene monohydrate, which has satisfactory thermal stability. The process for producing a compound represented by the general formula (2) is characterized by reacting a compound represented by the general formula (1) in the presence of a metal oxide comprising a metal selected from trivalent iron, pentavalent vanadium and hexavalent molybdenum and of a nonvolatile strong acid: | 08-18-2011 |
| 20110195512 | NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME - The present invention relates to a polynucleotide encoding a protein comprising an amino acid sequence shown in SEQ ID NO: 2, wherein the protein encoded by the polynucleotide has a hyaluronic acid binding ability, the protein, a method for measuring hyaluronic acid using the protein, and a reagent kit for measuring hyaluronic acid comprising the protein as a constituent. | 08-11-2011 |
| 20110138935 | POLYMER FOR FILLER FOR PREPROCESSING COLUMN - It is a subject of the present invention to provide a novel polymer; a filler for measuring a perfluoro compound having an acidic group at terminal which comprises said polymer; a column filled with said filler; and a measuring method for a perfluoro compound having an acidic group at terminal by using said column; as well as a filler for measuring a drug comprising the above-described polymer; a column filled with said filler; and a measuring method for a drug by using said column. | 06-16-2011 |
| 20110053220 | NOVEL PROTEIN CAPABLE OF BINDING TO HYALURONIC ACID, AND METHOD FOR MEASUREMENT OF HYALURONIC ACID USING THE SAME - The present invention relates to a polynucleotide encoding a protein comprising an amino acid sequence shown in SEQ ID NO: 2, wherein the protein encoded by the polynucleotide has a hyaluronic acid binding ability, the protein, a method for measuring hyaluronic acid using the protein, and a reagent kit for measuring hyaluronic acid comprising the protein as a constituent. | 03-03-2011 |
| 20110052448 | SPECIFIC COMPONENT MEASURING METHOD BY SPECTRAL MEASUREMENT - The present invention discloses a method for measuring an amount of an objective component to be measured in a sample, which comprises; preventing an electric charge in an atmosphere in a photometry chamber from transferring to the surface of a solution which generates light due to an energy variation of a substance induced by the objective component in the sample, measuring value of the light, and determining an amount of the objective component in the sample on the basis of the measured value thus obtained, and an instrument used for the method. | 03-03-2011 |
| 20110021400 | SEMICONDUCTOR SURFACE TREATING AGENT COMPOSITION AND METHOD FOR TREATING SEMICONDUCTOR SURFACE USING THE SEMICONDUCTOR SURFACE TREATING AGENT COMPOSITION - An object of the present invention is to provide a semiconductor surface treating agent composition, which can realize easy removing of an anti-reflection coating layer in a production process of a semiconductor device or the like at a low temperature in a short time, a method for treating a semiconductor surface using the same, and further a semiconductor surface treating agent composition, which can realize not only removing of both layer of an anti-reflection coating layer and a resist layer, but can realize even removing of a cured resist layer produced in an etching process, and a method for treating a semiconductor surface using the same. The semiconductor surface treating agent composition of the present invention is characterized by comprising a compound which generates a fluorine ion in water, a carbon radical generating agent, and water and optionally an organic solvent, and the method for treating a semiconductor surface of the present invention is characterized by using the composition. | 01-27-2011 |
| 20100330700 | SUBSTRATE FOR ASSAYING BETA-GLUCAN AND/OR ENDOTOXIN AND ASSAY METHOD - An object of the present invention is to provide a peptide derivative for determining β-glucan or endotoxin which allows high sensitivity measurement, and a method for determining β-glucan and/or endotoxin using the same. The present invention relates to (1) a peptide derivative represented by the following general formula [1]: | 12-30-2010 |
| 20100324314 | PROCESS FOR PRODUCING ESTER COMPOUND | 12-23-2010 |
| 20100311958 | CARRIER, METHOD AND REAGENT FOR OBTAINING SMALL RNA - An object of the present invention is to provide a carrier which enables to obtain a small RNA in high yield yet in high purity, a simple method for obtaining a small RNA and/or a target nucleic acid of small RNA using the same, and a reagent and a kit comprising the above-described carrier. | 12-09-2010 |
| 20100269903 | PROCESS FOR PRODUCING POLYCRYSTALLINE SILICON SUBSTRATE AND POLYCRYSTALLINE SILICON SUBSTRATE - Provided are: a safe, low-cost method of producing a polycrystalline silicon substrate excellent in photoelectric conversion efficiency by which a uniform, fine uneven structure suited to a solar cell can be simply formed on the surface of the polycrystalline silicon substrate; and a polycrystalline silicon substrate having a uniform, fine, pyramid-shaped uneven structure so that its reflectance can be significantly reduced. The uneven structure is formed on the surface of the polycrystalline silicon substrate by etching the polycrystalline silicon substrate with an alkaline etching solution containing at least one kind selected from the group consisting of a carboxylic acid having 1 or more and 12 or less carbon atoms and each having at least one carboxyl group in one molecule, and salts of the acids. | 10-28-2010 |
| 20100233035 | REAGENT CONTAINER - A reagent container having a plurality of open holding sections, each holding a reagent and into which a probe is inserted to suck the reagent. An opening of each of the holding sections is sealed with at least one sheet-like seal member. The reagent container includes a container body and a lid having a plurality of hollow piercing sections, formed on a lower surface of the lid, protruding downward for piercing the seal member at each of the openings, and openings, formed in an upper surface of the lid, communicating with piercing sections respectively to allow the probe to be inserted therethrough or withdrawn therefrom. | 09-16-2010 |
| 20100209972 | METHOD FOR SYNTHESIS OF SINGLE- OR DOUBLE-STRANDED DNA, AND KIT FOR THE SYNTHESIS - An object of the present invention is to provide a simple and safe method for synthesis of single-stranded or double-stranded DNA and a kit for performing the synthesis. The present invention relates to, (1) a method for synthesis of single-stranded DNA, comprising a nucleotide sequence corresponding to the template RNA, characterized by comprising the following steps: 1) Step 1 in which the template RNA is subjected to reverse transcription reaction, 2) Step 2 in which the solution obtained in the treatment of Step 1 is subjected to alkaline treatment; (2) a method for synthesis of double-stranded DNA, comprising a nucleotide sequence corresponding to the template RNA, characterized by comprising the following steps: 1) Step 1 in which the template RNA is subjected to reverse transcription reaction, 2) Step 2 in which the solution obtained in the treatment of Step 1 is subjected to alkaline treatment, 3) Step 3 in which the obtained single-stranded DNA is converted to a double strand, as well as (3) a kit for synthesis of single-stranded DNA and (4) a kit for synthesis of double-stranded DNA for use in the above-described method for synthesis. | 08-19-2010 |
| 20100200402 | PRESSURE MANIFOLD TO EQUALIZE PRESSURE IN INTEGRATION PCR-CE MICROFLUIDIC DEVICES - A device is presented that includes a chip having a plurality of wells that are optionally connected by capillary channels, and a manifold member configured to be disposed over the chip for equalizing pressure over the wells and capillary channels. | 08-12-2010 |
| 20100191020 | PROCESS FOR PRODUCING TRIPHENYLENE COMPOUND AND CRYSTAL OBTAINED BY THE PROCESS - An object of the present invention is to provide a process for producing high-purity hydroxytriphenylenes in which not only inexpensive raw materials can be used but also no complicated steps of deprotection such as dealkylation, and reduction and the like are necessary, and which is thereby advantageous in industrial production. Also there is provided a novel crystal of 2,3,6,7,10,11-hexahydroxytriphenylene monohydrate, which has satisfactory thermal stability. The process for producing a compound represented by the general formula (2) is characterized by reacting a compound represented by the general formula (1) in the presence of a metal oxide comprising a metal selected from trivalent iron, pentavalent vanadium and hexavalent molybdenum and of a nonvolatile strong acid: | 07-29-2010 |
| 20100126865 | Electrode for dielectrophoretic apparatus, dielectrophoretic apparatus, method for manufacturing the same, and method for separating substances using the electrode or dielectrophoretic apparatus - To provide an electrode for a dielectrophoretic apparatus in which a background detected by reflecting an excited light on an electrode present under the substance (molecule) is reduced and an S/N ratio is enhanced. Also, there is provided an dielectrophoretic apparatus, in an apparatus in which a liquid containing substances to be separated is present in a non-uniform electric field formed by a dielectrophoretic electrode, and separation is carried out by a dielectrophoretic force exerting on the substances, wherein the collecting ability of substances is enhanced. The present invention is characterized in that a vacant space is provided in an electrode whereby substances subjected to influence by a negative dielectrophoretic force can be concentrated in said vacant space of an electrode, or above or below portion of the space. | 05-27-2010 |
| 20100113830 | METHOD FOR PRODUCING ARYLHYDROXYLAMINE - Problem To provide a method for producing an arylhydroxylamine compound efficiently and safely under mild conditions. | 05-06-2010 |
| 20100112711 | METHOD OF DETECTING AMPLIFICATION OR DELETION IN GENOMIC DNA FRAGMENT - [Problems] To provide a CGH method, in particular a CGH microarray method, enabling detection at an elevated accuracy and elevated sensitivity. | 05-06-2010 |
| 20100098584 | CLINICAL ANALYSIS APPARATUS - [Objective] | 04-22-2010 |
| 20100087646 | REAGENT FOR ORGANIC SYNTHESIS REACTION CONTAINING ORGANIC TRIOL BORATE SALT - [Problem] To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. | 04-08-2010 |
| 20100041916 | PROCESS FOR PRODUCTION OF SULFONIC ACID ESTER - The present invention provides a method for producing a sulfonate ester efficiently and in high yield. | 02-18-2010 |
| 20090321263 | CLINICAL ANALYSIS APPARATUS - To enable reuse of expensive microchips in a clinical analysis apparatus, while constantly and efficiently obtaining accurate analysis results. A clinical apparatus employs microchips to analyze substances, which are contained in samples and are targets of measurement. The clinical analysis apparatus is equipped with: a stocking section; a dispensing mechanism, for dispensing reagents stocked in the stocking section and samples to the microchips; and a measuring section, for measuring the measurement target substance within the samples. The measuring section includes: a dispensing station, at which the microchips are provided; a detecting station, for detecting the measurement target substance; and a cleansing station, at which microchips are cleansed following detection of the measurement target substance. The dispensing station, the detecting station, and the cleansing station are provided at a predetermined pitch from upstream to downstream positions. The microchips are continuously rotated through the stations to perform measurement repeatedly. | 12-31-2009 |
| 20090298057 | Primer and Probe for Use in Detection of Mycobacterium Kansasii and Method for Detection of Mycobacterium Kansasii Using the Same - The present invention discloses an oligonucleotide which comprises a part or the entire sequence of the nucleotide sequence depicted in SEQ ID NO: 1, 2, 3 or 4, or a part or the entire sequence of a nucleotide sequence complementary to the nucleotide sequence, wherein the oligonucleotide is capable of hybridizing with the nucleotide sequence of | 12-03-2009 |
| 20090281333 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER - It is an object of the present invention to provide a commercially advantageous method for producing a cyclic disulfonic acid ester with high yield, the present invention discloses a method for producing a cyclic disulfonic acid ester represented by the general formula (3), which comprises reacting a silver alkanedisulfonate represented by the general formula (1) with a dihaloalkane represented by the general formula (2) in a nonpolar solvent. | 11-12-2009 |
| 20090275026 | Primer and Probe for Detection of Mycobacterium Intracellulare, and Method for Detection of Mycobacterium Intracellulare by Using the Primer and Probe - The present invention discloses an oligonucleotide which comprises a part or the entire sequence of the nucleotide sequence shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8, or a part or the entire sequence of a sequence complementary to the nucleotide sequence shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8, wherein the oligonucleotide is capable of hybridizing with a nucleotide sequence of | 11-05-2009 |
| 20090215097 | Novel Polymer and Method of Measuring Cholesterol Therewith - It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) and the determination method using the polymer comprising the following units as constituents: | 08-27-2009 |
| 20090129987 | Connected Reagent Container - Provided is a composite multi-reagent vessel for an autoanalyzer, which prevents incorrectly combining a plurality of reagents including a standard or a control, and eliminates the work for combining reagents for analysis. A plurality of containers are each capable of standing on their own and are connected together each with an opening portion at the top and each being detachable and capable of standing as the connected reagent containers, thereby forming the composite multi-reagent vessel for the autoanalyzer to have reagents for analyzing the same analytical item therein, and a small container to have a reagent therein that is held on a step or a concave portion formed at a shoulder portion of any of the connected reagent containers. | 05-21-2009 |
| 20090114250 | Pipetter cleaning device and cleaning method - Provided are a simple and inexpensive cleaning apparatus and a method for cleaning capable of effectively cleaning the outer wall surface of a pipette. A pipette to be cleaned is positioned in a concave portion of the cleaning apparatus, and a cleaning liquid passed through inside of the pipette strikes an inner circumferential surface of the concave portion and bounces therefrom to splash against the outer wall surface of the pipette, thereby cleaning the outer surface. With above arrangement, without using an ejection apparatus of cleaning water, effect equivalent to that with the ejection apparatus can be attained. Furthermore, both the inner wall surface and the outer wall surface of the pipette can be cleaned by a single operation using the same cleaning water, thereby attaining easy internal cleaning work and short cleaning time. | 05-07-2009 |
| 20090098024 | DISPENSING MECHANISM, DISPENSING APPARATUS AND DISPENSING METHOD FOR LIQUID TO BE DISPENSED - There is provided a dispensing mechanism for a liquid to be dispensed that does not damage microspherical bodies such as an erythrocyte and a liposome in the liquid to be dispensed when the liquid to be dispensed such as a sample and test liquid is sucked/discharged with a pipette. | 04-16-2009 |
| 20090069546 | PYRAZOLE-BASED CYANINE DYE - Problem Provided is a novel cyanine dye derivative with a pyrazole skeleton and an indole skeleton, having high sensitivity performance in a shorter wavelength region as compared with a conventional optical system, and showing high water solubility.
| 03-12-2009 |
| 20090068750 | Method of Determining Iron Concentration - The present invention discloses a method of measuring iron concentration in a sample, characterized by bringing the iron contained in the sample into contact with a metallochromic indicator for iron in the presence of lithium ion and determining the iron concentration based on the degree of resultant coloring, a reagent and a kit using therefor. | 03-12-2009 |
| 20090053729 | METHOD FOR DETECTION OF MUTANT GENE - Disclosed is a method for detecting mutation(s) in nucleotide sequence, which comprises performing a nucleic acid amplification reaction by using an oligonucleotide or a salt thereof as a primer and a nucleic acid in a sample as a template and detecting a reaction product, wherein the oligonucleotide is so modified at the nucleotide at the second position from the 3′-terminus as to inhibit the nucleic acid synthesis. Also disclosed is a kit for the method. According to the present invention, since it is possible to completely eliminate any false positive result in the determination and correspond to various mutation patterns by a single run of PCR1 reaction, it becomes possible to design a drug-resistance determination system, which can detect possible plural genetic mutations by a single run of multiplex PCR. | 02-26-2009 |
| 20090053698 | METHOD FOR OBTAINING SUBTRACTION POLYNUCLEOTIDE - The present invention provides a method for obtaining or amplifying a polynucleotide (a tester-specific polynucleotide), in which an amount existing in a sample (tester) is larger than the amount existing in another sample (driver), easily and within a short time as well as with high efficiency, a polynucleotide obtained (amplified) by such method, a method for identifying gene mutation in the tester, and a kit to be used in such methods. | 02-26-2009 |
| 20090036659 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP - To provide a method for efficiently and industrially deuterating the benzyl position of a —O-benzyl group formed by introducing a benzyl group, a benzyloxymethyl group and the like as a protecting group. | 02-05-2009 |
| 20090023140 | CROSSLINKING AGENT, CROSSLINKING METHOD, METHOD OF CONTROLLING GENE EXPRESSION, AND METHOD OF EXAMINING GENE FUNCTION - The present invention provides a crosslinking agent which have photodegradable protective groups at two ends to crosslink double-stranded nucleic acid, a nucleic acid and a protein or a polypeptide, or proteins or polypeptides, in particular, double-stranded RNA; a method for crosslinking a double-stranded RNA or the like using the same; a method for regulating gene expression, which can control the expression of a target gene at an arbitrary timing and location; and a method for examining a gene function. | 01-22-2009 |
| 20080269425 | Novel Catalyst - The present invention is directed to provide a catalyst for reduction, which is capable of reducing even mono-substituted alkynes to alkenes and does not require the coexistence (combined use) of a toxic compound, and a method for reduction from alkynes to alkenes using the catalyst; and relates to a palladium-supported polyethyleneimine compound obtained by contacting a polyethyleneimine, a palladium compound and hydrogen gas in an oxygen-free state, a method for producing the above palladium-supported polethyleneimine compound, a catalyst for reduction comprising the above palladium-supported polyethyleneimine compound, and a method for reducing from alkynes to alkenes characterized by contacting an alkyne and hydrogen in the presence of a palladium-supported polyethyleneimine compound, which is obtained by reacting a polyethyleneimine, a palladium compound and hydrogen gas in an oxygen-tree state. | 10-30-2008 |
| 20080234488 | Method of Deuteration Using Mixed Catalyst - The subject of the present invention is to provide a method for deuteration, which can obtain a compound having an aromatic ring and/or a heterocyclic ring at an improved deuteration ratio. The present invention relates to a method for deuteration of a compound having an aromatic ring and/or a heterocyclic ring, comprising reacting the compound having an aromatic ring and/or a heterocyclic ring with a heavy hydrogen source in the presence of an activated mixed catalyst of not less than two kinds of catalysts selected from among a palladium catalyst, a platinum catalyst, a rhodium catalyst, an iridium catalyst, a ruthenium catalyst, a nickel catalyst and a cobalt catalyst. | 09-25-2008 |
| 20080227118 | Protein Immobilization Method and Quantification Method - The present invention relates to a method for immobilizing a protein in a sample, which could not easily be immobilized by the conventional immobilization method, to a solid-phase; a method for quantitative determination of protein wherein an effect of inhibitory substance coexisting in a sample prepared using the immobilization method can be reduced; and a rapid and highly precise method for detecting an abnormal PrP and a method for determining BSE using the immobilization method as compared with the conventional method. The present invention provides: “a method for immobilizing a protein to a solid-phase comprising contacting the protein with the solid-phase having hydrophobic surface in the presence of a lower alcohol, and a halogenocarboxylic acid and/or a long chain alkyl sulfate, and an immobilizing reagent solution to be used therefor; a method for quantitative determination of protein comprising contacting a protein-staining solution with the solid-phase immobilized with a protein by the immobilization method, and determining a degree of color development generated thereby; an immunoblotting method wherein the solid-phase immobilized with a protein by the immobilization method is used; and a method for detecting an abnormal PrP a method for determining BSE by using the immobilization method.” | 09-18-2008 |
