VIRALYTICS LIMITED Patent applications |
Patent application number | Title | Published |
20150037287 | Method of Treating a Malignancy in a Subject and a Pharmaceutical Composition for Use in Same - There is a disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement regulatory protein. The virus may be a member of the Picornaviridae family. Coxsackie A-group viruses have been found to be particularly suitable. The cell adhesion molecule is desirably a member of the immunoglobulin (Ig) superfamily. Typically, the complement regulatory protein will be DAF. | 02-05-2015 |
20130164330 | Methods and Compositions for Treatment of Hematologic Cancers - The present invention relates to oncolytic Picornaviruses and methods and compositions for treating subjects having hematologic cancers. These include methods and compositions for treatment of myeloma, using disclosed Picornavirus such as Coxsackievirus, in methods of direct or indirect administration to subjects and ex vivo purging of malignant cells within auto grafts prior to transplantation. | 06-27-2013 |
20120328575 | Modified Oncolytic Viruses - The present invention provides an isolated selected Picornavirus capable of lytically infecting or inducing apoptosis in a cell substantially in the absence of intercellular adhesion molecule-1 (ICAM-1), and methods for treating subjects. | 12-27-2012 |