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Vion Pharmaceuticals, Inc.

Vion Pharmaceuticals, Inc. Patent applications
Patent application numberTitlePublished
20090075945Phosphate-bearing prodrugs of sulfonyl hydrazines as hypoxia-selective antineoplastic agents - Novel phosphate-bearing prodrugs of sulfonyl hydrazines have the formula presented below. Methods of treatment of cancer are claimed. The aforementioned prodrugs include enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates and metabolites from all stages. The aforementioned prodrugs are preferentially activated in hypoxic tumors and can be given either alone, or in combination with other anticancer agents or with phototheraphy or radiotherapy.03-19-2009
20080299556Alkylguanyltransferase Assays - This invention provides a method to determine alkylguanyltransferase activity in a sample, comprising steps of placing the sample in an appropriate condition so that the AGT is functional; contacting the sample with an AGT Detector under conditions permitting the binding of AGT and AGTD to produce a signal; and measuring the signal, thereby determining the AGT activity in said sample. This invention provides different uses of this method. 12-04-2008

Patent applications by Vion Pharmaceuticals, Inc.