| VECTOR TOBACCO, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20110214680 | APPROACHES TO IDENTIFY LESS HARMFUL TOBACCO AND TOBACCO PRODUCTS - Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX. | 09-08-2011 |
| 20110005534 | REDUCED RISK TOBACCO PRODUCTS AND USE THEREOF - Reduced risk tobacco-related products and methods of use. These tobacco-related products (e.g., cigarettes or filters) are designed to reduce the biological insult, for example, DSBs, cell death or perturbation of RNA transcriptome or proteome as compared to the amount of biological insult induced by another cigarette, such as a conventional or reference cigarette (e.g., 2R4F), in human cells, and to provide a reduced risk cigarette that meets a cigarette smoker's sensory/perception needs. | 01-13-2011 |
| 20100273171 | GLOBAL GENE EXPRESSION ANALYSIS OF HUMAN BRONCHIAL EPITHELIAL CELLS EXPOSED TO CIGARETTE SMOKE, SMOKE CONDENSATES, OR COMPONENTS THEREOF - Aspects of the present invention concern the identification of several methods to analyze the genes that are modulated in normal human bronchial epithelial (NHBE) cells after exposure to cigarette smoke condensates (CSC) or cigarette smoke (CS). Embodiments described herein include methods to identify a gene that is modulated in response to exposure to CSC or CS, methods to identify tobacco products that have a reduced potential to contribute to tobacco-related disease, methods to make tobacco products that have a reduced potential to contribute to a tobacco-related disease, methods to identify a subject's predilection to acquire a tobacco related disease, the use of particular genes as biomarkers for tobacco-related disease, and patterns of gene expression or genetic signatures that are unique to each particular tobacco product. | 10-28-2010 |
| 20100206317 | REDUCED RISK TOBACCO PRODUCTS AND USE THEREOF - Reduced risk tobacco-related products and methods of use. These tobacco-related products (e.g., cigarettes or filters) are designed to reduce the biological insult, for example, DSBs, cell death or perturbation of RNA transcriptome or proteome as compared to the amount of biological insult induced by another cigarette, such as a conventional or reference cigarette (e.g., 2R4F), in human cells, and to provide a reduced risk cigarette that meets a cigarette smoker's sensory/perception needs. | 08-19-2010 |
| 20100132726 | APPROACHES TO IDENTIFY LESS HARMFUL TOBACCO AND TOBACCO PRODUCTS - Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX. | 06-03-2010 |
