| VARIATION BIOTECHNOLOGIES, INC. Patent applications |
| Patent application number | Title | Published |
| 20110177163 | COMPOSITIONS AND METHODS FOR TREATING HEPATITIS A - The present application provides compositions and methods useful for treating hepatitis A. In particular, while hepatitis A vaccines are currently limited to parenteral administration routes (i.e., intramuscular injection), we have identified compositions that induce a protective response when administered orally. | 07-21-2011 |
| 20110097418 | COMPOSITIONS AND METHODS FOR TREATING INFLUENZA - The present application provides compositions and methods useful for treating influenza. As described herein, the compositions and methods are based on the development of peptides and peptide combinations which exhibit immunogenic properties against influenza. In some embodiments, the peptide combinations induce a protective response against multiple strains of influenza, e.g., seasonal strains of influenza or even the new pandemic influenza A (H1N1) virus of swine origin. | 04-28-2011 |
| 20110020381 | INFLUENZA VACCINE FORMULATION - Peptide-based anti-influenza formulations against influenza are disclosed. The peptides are derived from influenza-based epitopes. The formulations are based on peptide mixtures which may be formulated so that variability is present at particular residues. The formulations can be used to prepare vaccines for preventing influenza, particularly avian influenza. | 01-27-2011 |
| 20100267583 | METHOD AND KIT FOR DETECTION OF HEPATITIS A VIRUS NEUTRALIZING ANTIBODIES - A rapid immunoassay method for the detection of anti-Hepatitis A Virus (HAV) neutralizing antibodies is described herein. This microplate-based enzymatic assay may be applicable in virological diagnostics, in evaluating the immunogenicity of candidate immunogenic compositions, such as HAV vaccines, or in quantifying functional neutralizing antibodies during the course of HAV infection. | 10-21-2010 |
| 20100121029 | ANTI-HIV IMMUNOGENIC FORMULATION AND PROCESS FOR PREPARATION THEREOF - A process is disclosed for preparation of a immunogenic peptide mixture in a single synthesis. The peptide mixture collectively represents the in vivo variability seen in immunogenic epitopes from an HIV pathogen. The mixture is termed a hypervariable epitope construct (HEC). Immunization with a HEC evokes broadly reactive immunity against divergent strains of a pathogen upon which the HEC is based. | 05-13-2010 |
| 20090117141 | HIV VACCINE COMPOSITION - An anti-HIV vaccine composition is disclosed. The vaccine comprises an combination of immunogenic peptide mixtures, which mixtures may be prepared in a single synthesis. The composition collectively represents the in vivo variability seen in immunogenic epitopes from highly variable regions of HIV. Immunization with the vaccine elicits broadly reactive immunity (CTL and T helper cell responses) against the divergent strains of HIV upon which it is based. The vaccine may be formulated to target regionally distinct variability based on an HIV clade predominant in a geographical region. | 05-07-2009 |
| 20090104216 | Peptide-Based Influenza Vaccine Formulation - Peptide-based anti-influenza formulations against influenza A and B are disclosed. The peptides are derived from influenza-based epitopes. The formulations are based on peptide mixtures which may be formulated so that variability is present at particular residues. The formulations can be used to prepare vaccines for preventing influenza in human, avian, murine or equine animals. | 04-23-2009 |