| UNIVERSITY OF WASHINGTON through its Center for Commercialization Patent applications |
| Patent application number | Title | Published |
|---|
| 20120097551 | COPPER-BASED WATER OXIDATION CATALYSTS - Methods for electrolysis of water to oxygen gas are provided. The method utilizes dimeric copper cations in water at a basic pH. The cations are provided in the water by adding a complex in solid form with an appropriate anion, or through a “self-assembly” method whereby a copper salt and appropriate ligands are added to water adjusted to a basic pH. The cations decrease the overpotential of water electrolysis, thereby providing for efficient generations of oxygen gas using a catalyst formed from an abundant material (copper). | 04-26-2012 |
| 20120079630 | SUB-MICROSECOND-RESOLUTION PROBE MICROSCOPY - Methods and apparatus are provided herein for time-resolved analysis of the effect of a perturbation (e.g., a light or voltage pulse) on a sample. By operating in the time domain, the provided method enables sub-microsecond time-resolved measurement of transient, or time-varying, forces acting on a cantilever. | 03-29-2012 |
| 20110311499 | Secretion System and Methods for its Use - The present invention provides reagents and methods for inhibiting bacterial infection and abnormal cell growth, as well as for selection cloning of nucleic acid inserts. | 12-22-2011 |
| 20110305634 | Methods and systems for adenovirus interaction with desmoglein 2 (DSG2) - The present invention provides compositions and methods for treating disorders associated with epithelial tissues. | 12-15-2011 |
| 20110300186 | Functionalized Nano- and Micro-materials for Medical Therapies - Compositions containing an optionally surface-functionalized mesoporous support and a biologically active agent, and pharmaceutical compositions of the same, are provided herein. Such compositions can be useful in the treatment of tumors, for example, by injection of the composition at a location near the site of the tumor. | 12-08-2011 |
| 20110278541 | COLOR-SELECTIVE QUANTUM DOT PHOTODETECTORS - Photoconductive optoelectronic devices, such as photodetectors and photovoltaics, are provided. The devices are sensitized to a particular wavelength (or range of wavelengths) of electromagnetic radiation such that the devices provide increased performance efficiency (e.g., external quantum efficiency) at the wavelength. The devices include a photoconductive semiconductor layer spanning an electrode gap between two electrodes to provide a photoconductive electrical conduit. Abutting the semiconductor layer is a plurality of plasmonic nanoparticles. The improved efficiency of the devices results from wavelength-dependent plasmonic enhancement of device photosensitivity by the plasmonic nanoparticles. | 11-17-2011 |
| 20110191276 | OPEN INFORMATION EXTRACTION FROM THE WEB - To implement open information extraction, a new extraction paradigm has been developed in which a system makes a single data-driven pass over a corpus of text, extracting a large set of relational tuples without requiring any human input. Using training data, a Self-Supervised Learner employs a parser and heuristics to determine criteria that will be used by an extraction classifier (or other ranking model) for evaluating the trustworthiness of candidate tuples that have been extracted from the corpus of text, by applying heuristics to the corpus of text. The classifier retains tuples with a sufficiently high probability of being trustworthy. A redundancy-based assessor assigns a probability to each retained tuple to indicate a likelihood that the retained tuple is an actual instance of a relationship between a plurality of objects comprising the retained tuple. The retained tuples comprise an extraction graph that can be queried for information. | 08-04-2011 |
| 20110143356 | THERMOSTABLE POLYMERASES HAVING ALTERED FIDELITY AND METHODS OF IDENTIFYING AND USING SAME - The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more active polymerase mutants by genetic selection. For example, the invention provides a method for identifying a thermostable polymerase having altered fidelity by mutating at least one amino acid residue in an active site O-helix of a thermostable polymerase. The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases. The invention additionally provides a method for identifying one or more mutations in a gene by amplifying the gene with a high fidelity polymerase. The invention further provides a method for accurately copying repetitive nucleotide sequences using a high fidelity polymerase mutant. The invention also provides a method for diagnosing a genetic disease using a high fidelity polymerase mutant. The invention further provides a method for randomly mutagenizing a gene by amplifying the gene using a low fidelity polymerase mutant. | 06-16-2011 |
| 20110117668 | SELF-POWERED SMART DIAGNOSTIC DEVICES - Devices and methods are provided for immobilizing a diagnostic target (e.g., indicative of a disease) from a solution (e.g., a biological fluid). The diagnostic target is first bound to a capture conjugate that includes a reversibly-associative polymer moieties attached to a first binding moiety that binds to the diagnostic target. Once the diagnostic target is bound to the capture conjugate, the solution is subjected to a change in heat and/or pH to cause the reversibly-associative polymer moieties to aggregate. The aggregates are then immobilized (e.g., via filtration). | 05-19-2011 |
| 20110112772 | TRANSMISSION QUANTIFICATION OF OPEN PATH FTIR SPECTRA WITH TEMPERATURE COMPENSATION - A transmission quantification approach that is effective at quantifying the concentration of key atmospheric gases, including water vapor and methane, does not require a background spectrum and is immune to changes between background and absorbance spectra. By using local minima and maxima in transmission of a target gas, this approach creates two spectral arrays as long as a single beam input spectra. One of these spectral arrays represents the points in wave-number space that are less absorbing points, and the other represents the more absorbing points. A concentration for a given gas is calculated by determining what reference concentration creates a residual after division by a pure gas spectrum that forces these two arrays to converge. | 05-12-2011 |
| 20100297639 | QUANTITATIVE/SEMI-QUANTITATIVE MEASUREMENT OF EPOR ON CANCER CELLS - The present invention provides for assays useful in predicting whether a cancer patient risks suffering erythropoietin-induced tumor progression if treated with erythropoietin. More specifically, one embodiment provides for a validated quantitative reverse transcriptase polymerase chain reaction assay that detects erythropoietin receptor expression, thus indicating whether a cancer patient risks suffering erythropoietin-induced tumor progression if treated with erythropoietin. | 11-25-2010 |
| 20100209951 | METHODS FOR ASSAYING ALPHA-L-IDURONIDASE ENZYMATIC ACTIVITY - Methods for assaying α-L-iduronidase enzymatic activity and methods for screening newborns for Mucopolysaccharidosis Type-I. | 08-19-2010 |
