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University of Vermont and State Agricultural College

University of Vermont and State Agricultural College Patent applications
Patent application numberTitlePublished
20120061329APPARATUS AND METHOD FOR ULTRASOUND TREATMENT FOR BALLAST WATER MANAGEMENT - The invention provides a method of treating a target area with an ultrasound wave pattern, including: providing an ultrasound apparatus having an ultrasound wave generator operatively attached to a plurality of transducers, coupled to an immersible support and configured to emit an ultrasound wave; immersing the apparatus into a water environment; positioning the apparatus proximate to a target area to treat at least one in situ organism; and emitting a pattern of ultrasound waves from the transducers, the pattern of ultrasound waves additive in effect and emitted onto the target area to threat an in situ underwater organism.03-15-2012
20120058950DETECTION OF NEUROPEPTIDES ASSOCIATED WITH PELVIC PAIN DISORDERS AND USES THEREOF - Diagnostic assessment and therapeutic treatment of pelvic pain disorders, including bladder disorders, bowel disorders, and/or reproductive tissue or organ disorders that are characterized by increased expression of the neuropeptides CGRP and/or PACAP. Additionally, applicants have developed a transgenic non-human model for pelvic pain disorders, where the transgenic animal expresses in bladder sensory neurons a recombinant neuropeptide implicated in the pelvic pain disorder.03-08-2012
20110288023CANCER DRUG DELIVERY USING MODIFIED TRANSFERRIN - The invention provides modified Transferrin (Tf) molecules and conjugates of the Tf molecules with a therapeutic agent. The invention also provides methods of treating cancer wherein the therapeutic agents are chemotherapeutic agents. The modified Tf molecules improve the delivery of the conjugated agent to a target tissue. In some embodiments, the modified Tf molecule has a mutation which decreases the release of bound iron from a Tf complex. The complex can also contain, for instance, a carbonate, oxalate, or other anion to stabilize the Tf iron complex.11-24-2011
20110150887METHODS AND PRODUCTS RELATING TO GSK3BETA REGULATION - The invention relates to methods and compositions for regulation of GSK06-23-2011
20110029603Systems For and Methods Of Assessing Urinary Flow Rate Via Sound Analysis - Systems for and methods of assessing urinary flow rate via sound analysis. Embodiments of the uroflow measurement systems include a computer and a telephone or a digital recording mechanism to capture the sound of one or more urination events, which are stored as audio files in a database. The uroflow measurement systems may include sound analysis software for analyzing the strength and duration of each urination event and may include a web-based uroflow software application for viewing the results via the Internet or other network. In one embodiment, the sound analysis software performs the steps of reading in the raw data of a selected audio file, generating a plot of the audio signal amplitude vs. time, generating a plot of smoothed data for the purpose of presenting an outline of the flow, generating a main flow plot, which is a plot of the largest continuous flow that has a strength that is greater than a predetermined minimum, and generating a set of numerical values that correspond to the strength and duration of urination.02-03-2011
20100209048Optical Fiber Microscopy Launch System and Method - A sample slide, launch system, and method for microscopy having two optical fibers positioned proximate a sample slide with optical fiber mounting elements to deliver EMR to a surface of the sample slide at a critical angle for total internal reflection microscopy. In one exemplary embodiment, the EMR from the first optical fiber and the EMR from the second optical fiber may have different polarization states and/or wavelengths.08-19-2010
20100145471PROSTHETIC LUNG - A prosthetic lung for receipt by a lung space of a patient includes a mass exchange apparatus for use in blood/air mass exchange, an air sac and an air vessel. The mass exchange includes plural blood flow conduits for defining blood flow and a plural air flow conduits for defining air flow. The plural air flow conduits and the plural blood flow conduits at least partially include gas-permeable membrane material and the conduits are arranged relative to each other to enable transfer of oxygen from the air to the blood and transfer of carbon dioxide from the blood to the air. The mass exchange apparatus is provided with at least one first air port and at least one second air port, so that the air flow may be defined therebetween by the plural air flow conduits. The air sac defines an air sac cavity in fluid communication with at least one first air port of the mass exchange apparatus. The air vessel defines an air vessel cavity in fluid communication with at least one second air port of the mass exchange apparatus. The air vessel is provided with an air access port arranged, in use, to enable air flow communication with the trachea of the patient.06-10-2010
20100143899METHODS AND PRODUCTS FOR DIAGNOSING CANCER - The present invention relates to methods and kits for the detection and diagnosis of cancer or precancerous conditions. Methylation of specific genes has been identified as indicative of cancer and methods of the invention, in part, relate to the detection of methylation levels in cells as a determination of cancer or a precancerous condition in the cell.06-10-2010
20100129931Anti-Methylation-Controlled J Protein Antibodies and Uses Thereof - This application includes, in part, methods of preparing antibodies that specifically bind to tnethylation-controlling J (MCJ) polypeptide. In some aspects, the application also includes, hybridoma cell lines that produce antibodies that specifically MCJ polypeptide; antibodies and antigen-binding fragments thereof produced with the methods of the application,—and methods of using antibodies and antigen-binding fragments that specifically bind MCJ polypeptide for diagnosis and treatment of cancer.05-27-2010
20100069774Breath Biofeedback System and Method - A breath biofeedback method and system for encouraging a subject to modify respiration. The system includes a thoracic volume input module measuring thoracic volume data of the subject and a pattern module providing target breathing patterns in communication with a display generator. The display generator producing display information representing a displayable image including a first object having a first position determined as a function of the thoracic volume data and a second object having a second position determined as a function of the target breathing pattern and the thoracic volume data. The displayable image is designed such that when displayed on the display device the displayable image encourages the subject viewing the displayable image to modify respiration.03-18-2010
20090305310Methods for Determining Notch Signaling and Uses Thereof - The invention relates, in part, to methods of determining Notch signaling in cells, tissues and/or subjects. The invention additionally relates, in part, to diagnostic assays for cell differentiation-associated diseases or conditions and for screening tools in research and clinical applications.12-10-2009
20090245731Optical Fiber Microscopy Launch System and Method - A sample slide, launch system, and method for microscopy having a fiber insertion portal terminating within the sample slide and having a fiber insertion axis such that when an optical fiber is inserted within the fiber insertion portal the optical fiber is positioned so to deliver an EMR to a surface of the sample slide at a desired angle.10-01-2009
20090028505Optical Fiber Microscopy Launch System and Method - A launch system and method for microscopy having an optical fiber positioned proximate a sample slide with an optical fiber mounting element so as to deliver an EMR from the optical fiber into a first sample slide and to a surface of a second sample slide at a critical angle for total internal reflection at an interface of the surface of the second sample slide and a sample positioned proximate to the surface of the second sample slide.01-29-2009
20090011404Methods and compositions for optical detection of single-stranded polynucleotides - The invention relates to products and methods for determining, localizing, and quantitating single-stranded polynucleotides. The methods of the invention include the use of Gp32F protein and mutant Gp32F protein to monitor polynucleotide reactions such as DNA replication, annealing, and excision and to determine single-stranded polynucleotide structures such as gaps, flaps, and bubbles. 01-08-2009
20080275366Systems For And Methods Of Assessing Lower Urinary Tract Function Via Sound Analysis - Systems for and methods of assessing lower urinary tract function from urinary flow data via sound analysis and user-provided information regarding the lower urinary tract symptoms (LUTS) of frequency, urgency and urge incontinence. Embodiments of the LUTS assessment systems include a computer and a telephone or a digital recording mechanism to capture the sound of one or more urination events, which are stored as audio files in a database. The LUTS assessment systems may include sound analysis software for analyzing the strength and duration of each urination event and may include a web-based software application for viewing the results via the Internet or other network. The database stores information from multiple urination events, and combined with information regarding the lower urinary tract symptoms, serves as an objective tool to assess bladder function and monitor progression of disease or therapy effectiveness.11-06-2008
20080248567Methods and products for embryonic stem cell culture - The invention relates to methods and media for preparing and maintaining self-renewing pluripotent embryonic stem cells. The methods include, in some embodiments, culturing embryonic stem cells in culture medium that includes culture medium conditioned by cells that express wnt3a.10-09-2008

Patent applications by University of Vermont and State Agricultural College