University of Vermont and State Agricultural College Patent applications |
Patent application number | Title | Published |
20160058839 | LEPTIN FOR TREATING SYSTEMIC INFLAMMATORY RESPONSE SYNDROME - Provided are methods and compositions for reducing the severity of systemic inflammatory response syndrome (SIRS). The method comprises administering to an individual who has been diagnosed with SIRS, a composition comprising leptin. | 03-03-2016 |
20150329610 | METHODS AND COMPOSITIONS FOR EXPRESSING FUNCTIONAL CLASS XIV MYOSIN - The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of the invention may be useful to screen for and identify compounds that inhibit and treat parasitic infections and contamination. | 11-19-2015 |
20150210997 | METHODS AND COMPOUNDS FOR REDUCING THREONYL-tRNA SYNTHETASE ACTIVITY - The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is elevated as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by elevated TARS activity. | 07-30-2015 |
20150202257 | METHODS AND COMPOSITIONS FOR METABOLIC REGULATION - The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or compositions that increase metabolism in cells, tissues, organs, and/or subjects. In certain aspects the invention includes methods and/or compositions useful to decrease metabolism in cells, tissues, organs, and/or in subjects. | 07-23-2015 |
20150150950 | METHODS AND PRODUCTS RELATING TO GSK3 REGULATION - The invention relates to methods and compositions for regulation of GSK3β activity. The invention provides phosphorylated GSK3β polypeptides and antibodies that recognize such polypeptides The invention further includes methods for treating disorders that are associated with elevated or reduced GSK3β activity. | 06-04-2015 |
20150040472 | SAP-COLLECTING DEVICES, SYSTEMS AND METHODS FOR SAP-PRODUCING SAPLINGS - Sap-collecting devices, systems and methods for sap-producing saplings are disclosed. The saplings each have at least one stem, which is cut to form a top end at a reasonable height above ground. The sap-collecting system includes a sap-collecting device that fits over the top end and forms a vacuum-tight seal with the stem. The sap-collecting device includes an interior and an access port open to the interior. The access port can be connected to a line system. A vacuum system is operably connected to the line system and forms a vacuum within the sap-collecting device. This serves to draw the sap from the top end of the sapling, through the sap-collecting device, through the line system and to a collecting tank. A plantation growth, management, and sap-collecting system that comprises the sap-collecting system and a stand of saplings is also disclosed. | 02-12-2015 |
20140142152 | METHODS AND COMPOUNDS FOR TREATING CANCER - The invention includes, in part, methods and compounds for treating cancer including, but not limited to gliomas, melanomas, and neuroblastomas. In some embodiments of the invention, a glyceryltriacetate compound is administered to a subject in an amount effective to treat or prevent a cancer in the subject. | 05-22-2014 |
20140039340 | METHODS OF PREDICTING AND MONITORING LABOR - The invention includes, in part, methods and apparatus for determining the status of labor in a pregnant subject. In some embodiments of the invention, organ-level uterine function is determined as a measure of the status of labor such as non-labor (e.g. false labor), latent phase labor, active phase labor, or post-delivery. | 02-06-2014 |
20140020291 | MAPLE SYRUP PRODUCTION SPOUT ASSEMBLY WITH BACKFLOW CHECK VALVE - A maple syrup production spout assembly ( | 01-23-2014 |
20130224212 | METHODS AND PRODUCTS RELATING TO GSK3SS REGULATION - The invention relates to methods and compositions for regulation of GSK3β activity. The invention provides phosphorylated GSK3β polypeptides and antibodies that recognize such polypeptides. The invention further includes methods for treating disorders that are associated with elevated or reduced GSK3β activity. | 08-29-2013 |
20130082830 | Systems For and Methods of Digital Recording and Reproduction of Tactile Drawings - Systems and methods of digitally recording and reproducing tactile drawings are disclosed. The method includes moving a stylus over a path on the first tactile drawing medium to form a tactile feature thereon, and digitally recording the path of the moving stylus to generate digital path data. The method also include reproducing the tactile feature on a second tactile drawing medium operably disposed in a tactile printer based on the digital path data. The systems and methods include forming tactile drawings based on a digital graphics file, including filtering the digital graphics file to form a .RLD file suitable for forming a tactile drawing having features capable of being tactilely sensed. | 04-04-2013 |
20130075385 | Thermal Eraser For Tactile Drawings - A thermal eraser for erasing tactile drawing features from a tactile drawing medium, along with methods of erasing tactile drawing features formed on a tactile drawing medium, are disclosed. The thermal eraser has a heated tip that can be heated to a temperature sufficient to cause the tactile drawing feature to flow back into the surface of the tactile drawing medium. The heated tip has a tip temperature that can be controlled by a temperature-regulating circuit. A set-point temperature can be used to set the tip temperature and maintain the tip temperature. The thermal eraser can be controlled by hand or by an electro-mechanical device such as a tactile printer. | 03-28-2013 |
20130032544 | Systems and methods for reducing phosphorous in phosphorous-containing outflows - Systems and methods for removing phosphorous (P) from P-containing wastewater from agricultural and urban outflow sources are disclosed. The system includes at least one water attenuation unit (WAU) fluidly coupled to at least one main filter unit (MFU) that contains P-adsorbing material. A high-flow diverter unit is arranged between the WAU and the MFU and diverts a portion of the flow of influent wastewater at high flow rates. The P-filter system is compact and has a modular construction. The effluent wastewater discharged from the P-filter system has 60% to 90% less phosphorous than the influent wastewater. | 02-07-2013 |
20120329733 | METHODS AND PRODUCTS RELATED TO METABOLIC INTERACTIONS IN DISEASE - The invention involves methods of regulating cell growth and division to control disease processes by manipulating mitochondrial metabolism and the expression of cell surface immune proteins. The invention also involves related compositions and screening assays. | 12-27-2012 |
20120209049 | Method and System For the Selective Oxidative Decarboxylation of Fatty Acids - Selective, radically initiated oxidative decarboxylation may produce low viscosity renewable fuels from biologically derived fats and oils. Fatty acids and triglycerides may be decarboxylated using oxidants at a water/oil interface. The oxidants may be produced using photo-Fenton reagents. The reaction advantageously can be carried out at room temperature and pressure and has fewer unwanted byproducts than traditional decarboxylation techniques. | 08-16-2012 |
20120189584 | GENIPIN CROSS-LINKED FIBRIN GELS - The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect. | 07-26-2012 |
20120061329 | APPARATUS AND METHOD FOR ULTRASOUND TREATMENT FOR BALLAST WATER MANAGEMENT - The invention provides a method of treating a target area with an ultrasound wave pattern, including: providing an ultrasound apparatus having an ultrasound wave generator operatively attached to a plurality of transducers, coupled to an immersible support and configured to emit an ultrasound wave; immersing the apparatus into a water environment; positioning the apparatus proximate to a target area to treat at least one in situ organism; and emitting a pattern of ultrasound waves from the transducers, the pattern of ultrasound waves additive in effect and emitted onto the target area to threat an in situ underwater organism. | 03-15-2012 |
20120058950 | DETECTION OF NEUROPEPTIDES ASSOCIATED WITH PELVIC PAIN DISORDERS AND USES THEREOF - Diagnostic assessment and therapeutic treatment of pelvic pain disorders, including bladder disorders, bowel disorders, and/or reproductive tissue or organ disorders that are characterized by increased expression of the neuropeptides CGRP and/or PACAP. Additionally, applicants have developed a transgenic non-human model for pelvic pain disorders, where the transgenic animal expresses in bladder sensory neurons a recombinant neuropeptide implicated in the pelvic pain disorder. | 03-08-2012 |
20110288023 | CANCER DRUG DELIVERY USING MODIFIED TRANSFERRIN - The invention provides modified Transferrin (Tf) molecules and conjugates of the Tf molecules with a therapeutic agent. The invention also provides methods of treating cancer wherein the therapeutic agents are chemotherapeutic agents. The modified Tf molecules improve the delivery of the conjugated agent to a target tissue. In some embodiments, the modified Tf molecule has a mutation which decreases the release of bound iron from a Tf complex. The complex can also contain, for instance, a carbonate, oxalate, or other anion to stabilize the Tf iron complex. | 11-24-2011 |
20110150887 | METHODS AND PRODUCTS RELATING TO GSK3BETA REGULATION - The invention relates to methods and compositions for regulation of GSK | 06-23-2011 |
20100209048 | Optical Fiber Microscopy Launch System and Method - A sample slide, launch system, and method for microscopy having two optical fibers positioned proximate a sample slide with optical fiber mounting elements to deliver EMR to a surface of the sample slide at a critical angle for total internal reflection microscopy. In one exemplary embodiment, the EMR from the first optical fiber and the EMR from the second optical fiber may have different polarization states and/or wavelengths. | 08-19-2010 |
20100145471 | PROSTHETIC LUNG - A prosthetic lung for receipt by a lung space of a patient includes a mass exchange apparatus for use in blood/air mass exchange, an air sac and an air vessel. The mass exchange includes plural blood flow conduits for defining blood flow and a plural air flow conduits for defining air flow. The plural air flow conduits and the plural blood flow conduits at least partially include gas-permeable membrane material and the conduits are arranged relative to each other to enable transfer of oxygen from the air to the blood and transfer of carbon dioxide from the blood to the air. The mass exchange apparatus is provided with at least one first air port and at least one second air port, so that the air flow may be defined therebetween by the plural air flow conduits. The air sac defines an air sac cavity in fluid communication with at least one first air port of the mass exchange apparatus. The air vessel defines an air vessel cavity in fluid communication with at least one second air port of the mass exchange apparatus. The air vessel is provided with an air access port arranged, in use, to enable air flow communication with the trachea of the patient. | 06-10-2010 |
20100143899 | METHODS AND PRODUCTS FOR DIAGNOSING CANCER - The present invention relates to methods and kits for the detection and diagnosis of cancer or precancerous conditions. Methylation of specific genes has been identified as indicative of cancer and methods of the invention, in part, relate to the detection of methylation levels in cells as a determination of cancer or a precancerous condition in the cell. | 06-10-2010 |
20100129931 | Anti-Methylation-Controlled J Protein Antibodies and Uses Thereof - This application includes, in part, methods of preparing antibodies that specifically bind to tnethylation-controlling J (MCJ) polypeptide. In some aspects, the application also includes, hybridoma cell lines that produce antibodies that specifically MCJ polypeptide; antibodies and antigen-binding fragments thereof produced with the methods of the application,—and methods of using antibodies and antigen-binding fragments that specifically bind MCJ polypeptide for diagnosis and treatment of cancer. | 05-27-2010 |
20100069774 | Breath Biofeedback System and Method - A breath biofeedback method and system for encouraging a subject to modify respiration. The system includes a thoracic volume input module measuring thoracic volume data of the subject and a pattern module providing target breathing patterns in communication with a display generator. The display generator producing display information representing a displayable image including a first object having a first position determined as a function of the thoracic volume data and a second object having a second position determined as a function of the target breathing pattern and the thoracic volume data. The displayable image is designed such that when displayed on the display device the displayable image encourages the subject viewing the displayable image to modify respiration. | 03-18-2010 |
20090305310 | Methods for Determining Notch Signaling and Uses Thereof - The invention relates, in part, to methods of determining Notch signaling in cells, tissues and/or subjects. The invention additionally relates, in part, to diagnostic assays for cell differentiation-associated diseases or conditions and for screening tools in research and clinical applications. | 12-10-2009 |
20090245731 | Optical Fiber Microscopy Launch System and Method - A sample slide, launch system, and method for microscopy having a fiber insertion portal terminating within the sample slide and having a fiber insertion axis such that when an optical fiber is inserted within the fiber insertion portal the optical fiber is positioned so to deliver an EMR to a surface of the sample slide at a desired angle. | 10-01-2009 |
20090028505 | Optical Fiber Microscopy Launch System and Method - A launch system and method for microscopy having an optical fiber positioned proximate a sample slide with an optical fiber mounting element so as to deliver an EMR from the optical fiber into a first sample slide and to a surface of a second sample slide at a critical angle for total internal reflection at an interface of the surface of the second sample slide and a sample positioned proximate to the surface of the second sample slide. | 01-29-2009 |
20090011404 | Methods and compositions for optical detection of single-stranded polynucleotides - The invention relates to products and methods for determining, localizing, and quantitating single-stranded polynucleotides. The methods of the invention include the use of Gp32F protein and mutant Gp32F protein to monitor polynucleotide reactions such as DNA replication, annealing, and excision and to determine single-stranded polynucleotide structures such as gaps, flaps, and bubbles. | 01-08-2009 |
20080248567 | Methods and products for embryonic stem cell culture - The invention relates to methods and media for preparing and maintaining self-renewing pluripotent embryonic stem cells. The methods include, in some embodiments, culturing embryonic stem cells in culture medium that includes culture medium conditioned by cells that express wnt3a. | 10-09-2008 |