| UNIVERSITY OF UTAH FOUNDATION Patent applications |
| Patent application number | Title | Published |
|---|
| 20110304329 | LABELED PEPTIDES AND METHODS OF USE THEREOF FOR IMPROVED OXIDATION AND MAPPING OF DISULFIDE BRIDGES - Described herein are labeled proteins and methods of use thereof for identifying the position of multiple disulfide bridges present in the peptide. The methods combine the use of diselenide bridges and NMR-based mapping of the disulfide bridges. Also described herein are labeled proteins described above that contain fluorous bridges and spacers that facilitate oxidative folding of the protein. The resulting biorthogonal oxidation strategy for studying disulfide-rich peptides both improves oxidative folding and provides simultaneous determination of the disulfide crosslink connectivity in the peptide. The methods permit routine and facile production of disulfide-rich peptides. | 12-15-2011 |
| 20110294676 | MONOCHROME MULTIPLEX QUANTITATIVE PCR - Disclosed herein are methods and compositions for determining the copy number of a first target nucleic acid as compared to the copy number of a second target nucleic acid in a single well with a single detection label. For example, disclosed herein are methods and compositions for determining the copy number of a first target nucleic acid as compared to the copy number of a second target nucleic acid by a monochrome multiplex quantitative PCR (MMQPCR) in a single well with a single detection label. | 12-01-2011 |
