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UNIVERSITY OF TSUKUBA

TSUKUBA-SHI, JP

UNIVERSITY OF TSUKUBA Patent applications
Patent application numberTitlePublished
20120120408TWO-BEAM OPTICAL COHERENCE TOMOGRAPHY APPARATUS - The scanning speed of a sample in Doppler OCT, etc., is increased to enable quick measurement of blood flow rate, blood flow volume, etc. Wideband light from a light source 05-17-2012
20120065089Method For Detecting And Distinguishing Intrahepatic Cholangiocarcinoma - Disclosed are a method for early, sensitively and reliably detecting and distinguishing intrahepatic cholangiocarcinoma in a malignant tumor occurring primarily in the liver in a simple way, and a kit therefor. In the method, a glycan biomarker consisting of a lectin WFA (Wisteria floribunda Agglutinin)-binding glycoprotein derived from intrahepatic cholangiocarcinoma is used as a cancer marker to detect intrahepatic cholangiocarcinoma by detecting the cancer marker in a test specimen. The method for detecting intrahepatic cholangiocarcinoma can clearly differentiate intrahepatic cholangiocarcinoma from hepatocellular carcinoma and enables early detection and determination with a performance clinically acceptable in terms of applicability, sensitivity and precision.03-15-2012
20110318762Graft-Versus-Host Disease Predicting Marker and Use Thereof - A test method that provides data useful in predicting the probability of onset of acute graft-versus-host disease (GVHD) is described along with a kit for performing the method, and a pharmaceutical preparation and a molecular targeted therapy for treating or preventing GVHD. The test method includes measuring the blood DNAM-1 concentration of a patient of hematopoietic stem cell transplantation from bone marrow or the like over a period after the transplantation to provide data concerning the transition of the concentration to an abnormally high level deviating from the normal range, whereby the probability of the development of acute graft-versus-host disease is predicted, the risk of the development is estimated, or therapeutic effects after the development are evaluated. Concerning the molecular targeted therapy and pharmaceutical preparation used therefor wherein blood DNAM-1 of a GVHD patient or a graft recipient that is a possible patient is used as a target molecule, GVHD is treated or prevented by administering an anti-DNAM-1 antibody that is a neutralizing antibody.12-29-2011
20110262944CONSTRUCTION AND CRYSTALLIZATION OF EXPRESSION SYSTEM FOR RNA POLYMERASE PB1-PB2 PROTEIN DERIVED FROM INFLUENZA VIRUS - The present invention aims to express influenza virus RNA polymerase on a large scale, to crystallize the influenza virus RNA polymerase, and to provide a method for screening a substance capable of serving as an active ingredient in anti-influenza drugs.10-27-2011
20110249797RADIATION TREATMENT SYSTEM - A radiation treatment system that can apply radiation to a respiratory moving organ (such as, a lung, a liver or the like) with high precision is provided. A radiation treatment system according to the present invention as solving means is characterized in that when medical treatment target position information obtained by executing pattern matching processing on the inside of each frame of a fluoroscopic X-ray image for detecting a medical treatment target position achieved under medical treatment on the basis of a template image of an area containing a medical treatment target position of a patient, which is achieved in advance, is within a predetermined error range with respect to the medical treatment target position information based on the template image, and also a timing is an application timing of medical treatment radiation which is set on the basis of motion information of a body surface, a signal for applying medical treatment radiation is generated; and in the other cases, a signal for stopping the application is generated, whereby the application of the medical treatment radiation is controlled on the basis of these signals.10-13-2011
20110187812COMMUNICATION WALL PANEL, NURSING CARE SYSTEM HAVING COMMUNICATION WALL PANEL, AND CONFERENCE SYSTEM HAVING COMMUNICATION WALL PANEL - A communication wall panel includes an interior panel member to be attached to a room as an interior wall material thereof; an information obtaining part provided in the interior panel member and configured to obtain information associated with a person in the room; a notification part provided in the interior panel member and configured to notify the person in the room of information; a communication part provided in the interior panel member and configured to perform communication with a server installed in a location other than the room; and a control part provided in the interior panel member and configured to control the information obtaining part and the notification part. The communication part is configured to transmit information obtained from the information obtaining part to the server and to output information transmitted from the server to the notification part.08-04-2011
20110166491BIOLOGICAL SIGNAL MEASURING WEARING DEVICE AND WEARABLE MOTION ASSISTING APPARATUS - A biological signal measuring wearing device configured to measure a biological signal from the body surface of a wearer includes a wearing device body configured to cover the body surface of the wearer, multiple biological signal detecting parts provided on a predetermined part of the inner surface of the wearing device body and configured to detect a signal from the body surface of the wearer, a biological signal obtaining part configured to obtain the biological signal from the signal detected by the biological signal detecting parts, and a signal communicating part configured to communicate the biological signal obtained by the biological signal obtaining part to an external apparatus.07-07-2011
20110162102Novel root-knot-nematode-resistance gene and application thereof - This invention relates to an excellent root-knot nematode-resistance gene and a method for using the same. More particularly, this invention relates to a novel root-knot nematode-resistance gene that is unaffected by high temperature and is applicable to and quantitatively resistant to a wide variety of root-knot nematode species and strains and a root-knot nematode-resistant transgenic plant into which such gene has been introduced.06-30-2011
20110150953METHOD FOR PRODUCING VESICLE, VESICLE OBTAINED BY THE PRODUCTION METHOD, AND W/O/W EMULSION FOR PRODUCING VESICLE - A vesicle is produced by: a step of producing a W/O emulsion from an aqueous solution containing a substance to be entrapped in a vesicle in a dissolved or suspended state and an organic solvent phase containing a lipid having emulsification capacity, which can constitute the vesicle; a step of producing a W/O/W emulsion from the W/O emulsion and an external water phase solution of a water-soluble emulsifier, which does not destroy a vesicle lipid membrane; and a step of removing the organic solvent phase from the W/O/W emulsion, so as to form a vesicle. This method simultaneously achieves a high entrapment yield of an active ingredient and the control of a particle diameter.06-23-2011
20110125327BUILDING MANAGEMENT APPARATUS - A building management apparatus that can provide a comfortable environment based on diligent control is provided. A building management apparatus 05-26-2011
20110118585EYEBALL TISSUE CHARACTERISTIC FREQUENCY MEASUREMENT DEVICE AND NON-CONTACT TONOMETER UTILIZING THE SAME - A non-contact tonometer of the present invention quantitatively measures characteristic vibration of the cornea of an eyeball and measures a true ocular pressure utilizing this vibration, and comprises: an air flow spray unit (05-19-2011
20110118564BLOOD VESSEL CHARACTERISTICS MEASURING APPARATUS AND BLOOD VESSEL CHARACTERISTICS MEASURING METHOD - The blood vessel characteristics measuring apparatus 05-19-2011
20110042237ELECTROCHEMICAL SENSOR DEVICE AND ELECTROCHEMICAL MEASURING METHOD USING THE SAME - Provided is an electrochemical sensor device capable of micromachining a channel while maintaining its measurement sensitivity and of reliably quantitating an analyte in a trace amount of a sample. An electrochemical sensor device includes: a channel portion formed in a substrate; and working electrodes for subjecting an analyte in a solution flowing in the channel portion to electrochemical measurement, the electrochemical sensor device includes a plurality of measuring portions individually provided with the working electrodes, and each of the working electrodes has a plurality of conductive protrusion portions formed to protrude from a bottom surface of each of the measuring portions.02-24-2011
20100304375Influenza Virus Genome Replication and Transcription System in Yeast Cells - A system in which vRNP purified from influenza virus particles is introduced into yeast (12-02-2010
20100296965ALLOY SOLDER AND ALLOY SOLDER MANUFACTURING METHOD - The present invention solves the problem of the bonding strength of a Pb-free alloy solder being inferior to that of the conventional Pb-containing alloy solder and provides a Pb-free alloy solder satisfactory in bonding reliability.11-25-2010
20100280628WEARABLE ACTION-ASSIST DEVICE, AND METHOD AND PROGRAM FOR CONTROLLING WEARABLE ACTION-ASSIST DEVICE - A wearable action-assist device which assists or executes an action of a wearer by substituting for the wearer is provided with an action-assist tool 11-04-2010
20100271051CENTROID POSITION DETECTOR DEVICE AND WEARING TYPE ACTION ASSISTANCE DEVICE INCLUDING CENTROID POSITION DETECTOR DEVICE - Load measuring parts 10-28-2010
20100217163ROTATION ADJUSTMENT APPARATUS AND METHOD OF CONTROLLING ROTARY APPARATUS - [Problem to be Solved] It is an object of the present invention to reduce energy consumed when a rotary apparatus is used and to suppress abrasion and breakage on the rotary apparatus and a driving apparatus which drives the rotary apparatus.08-26-2010
20100200073FLUID TRANSPORT DEVICE AND FLUID TRANSPORT CONTROL METHOD - A fluid transport device transports fluid containing electrolytes within a flow channel. At least a portion of the inner walls of the flow channels are hydrophilic from the inlet to the outlet thereof except at least one valve portion. The device also includes: the valve portions, which are hydrophobic and function to block transport of at least one fluid; electrodes, which are provided at the at least one valve portion and function to reduce the surface tension of the fluid; and air vents, which are provided at the at least one valve portion and function to introduce air in order to block the fluid.08-12-2010
20100184267METHOD OF FORMING SILICON OXIDE FILM AND METHOD OF PRODUCTION OF SEMICONDUCTOR MEMORY DEVICE USING THIS METHOD - To form a good quality silicon oxide film provided with both a superior Qbd characteristic and Rd characteristic, a wafer W is loaded into a plasma treatment apparatus where the surface of a silicon layer 07-22-2010
20100166840LIPOSOME HAVING LIPID MEMBRANE CONTAINING BACTERIAL CELL COMPONENT - The object is to provide a liposome by which a bacterial cell component insoluble in water and an organic solvent (e.g., BCG-CW) can be pharmaceutically prepared in a form applicable to a living body (i.e., a form in which the bacterial cell component can be dispersed in an aqueous solvent and has a controlled size) without using any surfactant. Disclosed is a liposome having a lipid membrane containing a bacterial cell component insoluble in water and an organic solvent (e.g., BCG-CW).07-01-2010
20100146666METHOD FOR PRODUCING PLANT WITH MODIFIED FLOWER MORPHOLOGY - A plant with modified flower morphology is produced by suppressing a function of a transcription factor involved in determining the polarity of plants. More particularly, a plant with modified flower morphology is produced by the steps of obtaining a transformed cell by introducing a chimeric DNA in which a DNA encoding a transcription factor involved in determining the polarity and a functional peptide converting a transcription factor into a transcription repressor are fused; and regenerating a transformed plant from the transformed cell.06-10-2010
20100121232MOTION-ASSIST SYSTEM OF WEARABLE MOTION-ASSIST DEVICE, WEARABLE MOTION-ASSIST DEVICE, AND MOTION-ASSIST METHOD OF WEARABLE MOTION-ASSIST DEVICE - In the present invention, the motion state of the wearable motion-assist device 05-13-2010
20100029791METHOD FOR PRODUCING VESICLE, VESICLE OBTAINED BY THE PRODUCTION METHOD, AND METHOD FOR PRODUCING FROZEN PARTICLE USED IN PRODUCTION OF VESICLE - A W/O emulsion is produced from an aqueous solution containing a substance to be entrapped in a vesicle in a dissolved or suspended state and an oil phase containing an emulsifier; subsequently, the W/O emulsion is cooled to a temperature at which the aqueous solution of the W/O emulsion becomes a frozen particle and the oil phase maintains a liquid state, and the oil phase is removed; thereafter, an oil phase containing a vesicle constituent lipid is added to the frozen particle, and the obtained mixture is then stirred, so as to substitute the emulsifier on the surface of the frozen particle with the vesicle constituent lipid; and thereafter, an external water phase is added to the frozen particle coated with a lipid membrane, so as to hydrate the lipid membrane by the external water phase. This process achieves a high entrapment yield of a desired substance while controlling desired physical properties such as particle diameter.02-04-2010
20090319054WEARABLE ACTION-ASSIST DEVICE, AND METHOD AND PROGRAM FOR CONTROLLING WEARABLE ACTION-ASSIST DEVICE - A wearable action-assist device which assists or executes an action of a wearer by substituting for the wearer is provided with an action-assist tool 12-24-2009
20090293161CANTILEVER DEVICE AND CANTILEVER CONTROLLING METHOD - The amplitude control of a cantilever based on the van der Pol model is performed through a feedback using the measurement data on a deflection of the cantilever. A self-oscillating circuit integrates a deflection angle signal of a cantilever detected by a deflection angle measuring mechanism using an integrator, multiplies a resulting integral value by linear feedback gain K11-26-2009
20090275837ULTRASONIC MEASUREMENT APPARATUS - A processing unit calculates first displacement related information concerning a first direction of an object to be measured by using data in either one of an increase period and a decrease period of a force applied to the objected to be measured, among first received data received by a first ultrasonic probe. In addition, the processing unit calculates second displacement related information concerning a second direction of the object to be measured by using data in the same period as that used to calculate the first displacement related information, among second received data received by a second ultrasonic probe.11-05-2009
20090220811TITANIUM-TANTALUM BASE SHAPE MEMORY ALLOYS, ACTUATOR AND ENGINE - A Titanium-Tantalum base shape memory alloy is provided which possesses high machinability and is suitable for repeated high temperature operation. The Titanium-Tantalum base shape memory alloy consists of 15 mol %-40 mol % Tantalum, additive elements, and the balance Titanium and impurities.09-03-2009
20090218013HIGH TEMPERATURE SHAPE MEMORY ALLOY, ACTUATOR AND MOTOR - A high temperature shape memory alloy is provided which possesses high machinability and is suitable for high temperature applications. The high temperature shape memory alloy consists of Ni from 34.7 mol % to 48.5 mol %, at least either Zirconium or Hafnium as transformation temperature increasing additives, with the sum of which 6.8 mol % to 22.5 mol %, and at least either Niobium or Tantalum as machinability improving additives, with the sum of which 1 mol % to 30 mol %; and Boron less than 2 mol %; and Titanium as the balance; and unavoidable impurity.09-03-2009
20090186017Graft-Versus-Host Disease Predicting Marker and Use Thereof - A test method that provides data useful in predicting the probability of onset of acute graft-versus-host disease (GVHD) is described along with a kit for performing the method, and a pharmaceutical preparation and a molecular targeted therapy for treating or preventing GVHD. The test method includes measuring the blood DNAM-1 concentration of a patient of hematopoietic stem cell transplantation from bone marrow or the like over a period after the transplantation to provide data concerning the transition of the concentration to an abnormally high level deviating from the normal range, whereby the probability of the development of acute graft-versus-host disease is predicted, the risk of the development is estimated, or therapeutic effects after the development are evaluated. Concerning the molecular targeted therapy and pharmaceutical preparation used therefor wherein blood DNAM-1 of a GVHD patient or a graft recipient that is a possible patient is used as a target molecule, GVHD is treated or prevented by administering an anti-DNAM-1 antibody that is a neutralizing antibody.07-23-2009
20090047368Polymeric polyphenol extracted from fermented tea, therapeutic agent for mitochondrial disease, preventive/therapeutic agent for diabetes mellitus, and food or beverage - [Problem] To provide a new pharmacological action for high-molecular-weight polyphenols02-19-2009
20090022782Blood Retainable Device Exhibiting Selective Degradability in Tumor Tissue - A phospholipid derivative useful for the preparation of liposomes for efficient uptake of an antitumor agent or a gene intracellularly by a target tumor cell, which comprises a residue of an alcohol compound and a residue of a phospholipid, and comprising a peptide between the residue of an alcohol compound and the residue of a phospholipid, and wherein (a) the alcohol compound is an alcohol compound selected from poly(alkylene glycols) and the like, (b) the phospholipid is a phospholipid selected from phosphatidylethanolamines, phosphatidylcholines, phosphatidylserines and the like, and (c) the peptide is a peptide comprising a substrate peptide that can serve as a substrate of a matrix metalloproteinase, provided that one amino acid residue or an oligopeptide containing 2 to 8 amino acid residues may bind to one or both ends of the substrate peptide.01-22-2009
20080299579NOVEL CANCER MARKER AND USE THEREOF - This invention provides a method for cancer diagnosis comprising measuring an endogenous antisense RNA whose relative expression to a sense RNA changes cancer-specifically in RNA-containing samples collected from a mammal. Also provided are endogenous antisense RNAs useful as cancer markers, and cancer diagnostic reagents containing the same.12-04-2008

Patent applications by UNIVERSITY OF TSUKUBA