University of Southampton Patent applications |
Patent application number | Title | Published |
20160060703 | HAPLOTYPE DETECTION - A method of diagnosing Ankylosing Spondylitis (AS), a spondyloarthropathy, arthritis, psoriasis, type-1 diabetes or a carcinoma comprising typing the ERAP1 haplotype of an individual. | 03-03-2016 |
20160015796 | HER2/NEU CANCER VACCINE - Protein conjugate comprising a protein antigen for generating an immune response against the HER2/neu protein and an immunogenic carrier covalently bonded to said protein antigen, wherein said protein antigen
| 01-21-2016 |
20150306586 | GAS AND LIQUID PHASE CATALYTIC BECKMANN REARRANGEMENT OF OXIMES TO PRODUCE LACTAMS - Methods for producing lactams from oximes by performing a Beckmann rearrangement using a silicoaluminophosphate catalyst are provided. These catalysts may be used in gas phase or liquid phase reactions to convert oximes into lactams. High conversion of oxime and high selectivity for the desired lactams are produced using the disclosed methods, including high conversion and selectivity for ε-caprolactam produced from cyclohexanone oxime and high conversion and selectivity for ω-laurolactam produced from cyclododecanone oxime. | 10-29-2015 |
20150126732 | GAS AND LIQUID PHASE CATALYTIC BECKMANN REARRANGEMENT OF OXIMES TO PRODUCE LACTAMS - Methods for producing lactams from oximes by performing a Beckmann rearrangement using a silicoaluminophosphate catalyst are provided. These catalysts may be used in gas phase or liquid phase reactions to convert oximes into lactams. High conversion of oxime and high selectivity for the desired lactams are produced using the disclosed methods, including high conversion and selectivity for ε-caprolactam produced from cyclohexanone oxime and high conversion and selectivity for ω-laurolactam produced from cyclododecanone oxime. | 05-07-2015 |
20150087787 | POLYPROPYLENE BLENDS AND PROCESSES FOR PRODUCING POLYMERIC COMPOSITIONS - Polymer blends of polypropylene homopolymer and propylene-α-olefin interpolymer. Processes for producing polymeric compositions comprising control-cooling heated blends of polypropylene and propylene-α-olefin interpolymer. Such polymeric compositions can be employed in forming coated wires and cables. | 03-26-2015 |
20140377178 | RADIOFLUORINATION METHOD - The present invention relates to a method of labelling biological molecules with | 12-25-2014 |
20140284932 | TURBINE GENERATOR - The invention relates to the generation of electricity from flowing fluid and in the preferred embodiment to a horizontal axis turbine and generator assembly. The present invention is applicable to water turbines and the invention is described in relation to this application. It is however to be appreciated that it is applicable to wind turbines. The present invention provides turbine generator for generating electrical power from flowing fluid comprising a rotatable hub having an external surface and a rotational axis arranged, in use, parallel to the direction of the flow, a plurality of blades mounted on the external surface of the hub and extending radially outwards from the hub; a plurality of magnets mounted on a surface inside the rotatable hub said surface arranged to rotate with the rotatable hub thereby forming a rotor of an electrical generator, and a plurality of non-rotating coils fixed to a stationary cylindrical core within the periphery of the rotatable hub, said coils and core thereby forming a stator of the electrical generator. | 09-25-2014 |
20140280639 | Methods, Systems, and Devices for Analyzing Social Media Content - A system for analyzing social media content and for determining the influence types of different social media members is disclosed. The system categorizes users according to their influence on the social media conversation and displays information related to this categorization in schematic form. The popularity of a particular topic can be analyzed to determine when the topic resonates and becomes more popular within the social network. In some embodiments, the categorization of the users and schematic display of information can be conducted in real-time. | 09-18-2014 |
20140176952 | MICROFLUIDIC ABSORPTION CELL - An absorption cell for microfluidic chemical analysis made from tinted or coloured polymers, for example polymethylmethacrylate (PMMA), in which microfluidic channels are cut. Light is coupled into the absorption cell via two windows (typically 200 um thick) that are retained at either end of the channel. Absorption is measured using a light source, such as a light emitting diode (LED) and a photodiode butted against the windows. Spurious scattered and/or reflected light is absorbed by the coloured polymer over the length of the measurement cell, while very little light loss occurs at the coupling windows. | 06-26-2014 |
20140133222 | PHASE CHANGE MEMORY DEVICES AND METHODS COMPRISING GALLIUM, LANTHANIDE AND CHALCOGENIDE COMPOUNDS - A new class of phase change materials has been discovered based on compounds of: Ga; lanthanide; and chalcogenide. This includes compounds of Ga, La, and S (GLS) as well as related compounds in which there is substitution of S with O, Se and/or Te. Moreover, La can be substituted with other lanthanide series elements. It has been demonstrated that this class of materials exhibit low energy switching. For example, the GLS material can provide an optical recording medium with erasability 3-5 dB greater than the erasability of GeSbTe (GST) material which is the standard material for phase change memories. | 05-15-2014 |
20130251706 | COMBINED USE OF FC GAMMA RIIB (CD32B) AND CD20 - SPECIFIC ANTIBODIES - The invention provides a method of treating a patient having target cells that express FcyRIIb, the method comprising administering (i) an antibody molecule that specifically binds a surface antigen of the target cell, which antibody molecule has an Fc domain capable of binding FcyRIIb; in combination with (ii) an agent that prevents or reduces binding between the Fc domain of the antibody molecule and FcyRIIb; characterized in that the patient is selected on the basis that their target cells express an elevated level of FcyRIIb. | 09-26-2013 |
20130245323 | Ammoximation Process - A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms. | 09-19-2013 |
20130245322 | Ammoximation Process - A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M | 09-19-2013 |
20130230579 | IMMUNOGENIC COMPOSITION COMPRISING NEISSERIA MENIGITIDIS MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN - An immunogenic composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof, wherein the composition is capable of eliciting an immune response when administered to a human or non-human animal, and uses thereof. A pharmaceutical composition or a vaccine composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof. | 09-05-2013 |
20130176836 | MAGNETIC FIELD GENERATOR - A metallic ring is made of two metals, wherein one metal forms a major arcuate portion and the other a minor arcuate portion of the ring, thereby forming a thermocouple-type structure as a result of the two inter-metallic junctions. The metallic ring supports a surface plasmon whose energy is matched to the energy, i.e. wavelength, of an incident light beam so that the oscillating electromagnetic field of the light resonates with the plasmon. The resonating plasmon causes a temperature difference to arise between the two inter-metallic junctions in the ring. The different Seebeck coefficients of the two metals results in the temperature difference causing a net current to flow around the ring, which in turn generates a magnetic field. Such a thermoelectric metamaterial ring transforms high frequency optical energy into long duration magnetic radiation pulses in the terahertz range. Applications of these devices include high density magnetic recording, magnetic field spectroscopy, and efficient terahertz radiation sources. | 07-11-2013 |
20130175068 | Recyclable Thermoplastic Insulation with Improved Breakdown Strength - The disclosure provides a process for producing a material with improved break-down strength. The process includes heating a polymeric composition composed of a low density polyethylene (LDPE) and a minority amount of a high density polyethylene (HDPE). The polymeric composition is heated to at least the melting temperature of the HDPE. The process includes control-cooling the heated polymeric composition at a cooling rate from 0.1° C./min to 20° C./min, and forming a polymeric composition. The control-cooled polymeric composition has a unique morphology which improves breakdown strength. Also provided is a coated conductor with an insulating layer composed of the polymeric composition with the unique morphology. The insulating layer exhibits improved breakdown strength. | 07-11-2013 |
20130166077 | APPARATUS AND METHOD OF VIBRATION CONTROL - Vibration control apparatus for controlling vibration of a structure ( | 06-27-2013 |
20130164315 | Vaccines - Screening Method - The present invention provides a screening method for identifying a peptide capable of inducing a T cell response comprising:
| 06-27-2013 |
20130128341 | Optical Amplifier System and Method - The invention provides a system for use in an optical communication network to reduce noise comprising means for tapping a low noise signal from said network and a phase sensitive amplifier (PSA) for conditioning said tapped signal by means for removing modulation of the tapped signal to allow for phase locking of the tapped signal. A laser source provides phase locked reference signals to generate at least one pump signal, wherein the at least one pump signal provides correct phase alignment for optimum PSA operation. The invention makes use of injection locked and/or phase locked laser sources in conjunction with low power input tap couplers, or post/mid amplification taps to provide the required phase locked reference signals without degrading the input loss or noise. The use of injection/phase locked local lasers suppresses the detrimental impact of the low tapped power or added noise in the generation of the required pump signals. | 05-23-2013 |
20130055830 | APPARATUS AND METHOD FOR MEASUREMENT OF HAND JOINT MOVEMENT - Signal processing apparatus ( | 03-07-2013 |
20130047728 | APPARATUS AND METHOD FOR THE MANIPULATION OF OBJECTS USING ULTRASOUND - A method and apparatus for manipulating particles. The apparatus comprising an ultrasound source for providing a variable ultrasound signal within a region of interest, and a controller connected to the ultrasound source such that it provides a control signal to the ultrasound source. The variable ultrasound signal creates a pressure field within the region of interest, the shape and/or position of which can be altered by changing the control signal input to the ultrasound source such that a particle within the region of interest will move in response to changes in the pressure field. | 02-28-2013 |
20120227761 | CLEANING APPARATUS AND METHOD, AND MONITORING THEREOF - An apparatus for cleaning a surface, the apparatus including a body defining a chamber, an inlet for liquid flow into the chamber, an outlet for liquid flow from the chamber, a nozzle connected to the outlet for generating an output flow of liquid for cleaning a surface, an acoustic transducer associated with the body to introduce acoustic energy into the liquid within the chamber whereby the acoustic energy is present in the liquid flowing out of the nozzle, and a gas bubble generator for generating gas bubbles within the liquid flowing out of the nozzle. | 09-13-2012 |
20120112165 | Optical Device - An improved optoelectronic device is described, which employs optically responsive nanoparticles and utilises a non-radiative energy transfer mechanism. The nanoparticles are disposed on the sidewalls of one or more cavities, which extend from the surface of the device through the electronic structure and penetrate the energy transfer region. The nanoparticles are located in close spatial proximity to an energy transfer region, whereby energy is transferred non-radiatively to or from the electronic structure through non-contact dipole-dipole interaction. According to the mode of operation, the device can absorb light energy received from the device surface via the cavity and then transfer this non-radiatively or can transfer energy non-radiatively and then emit light energy towards the surface of the device via the cavity. As such, the deice finds application in light emitting devices, photovoltaic (solar) cells, displays, photodetectors, lasers and single photon devices. | 05-10-2012 |
20110257390 | AMMOXIMATION PROCESS - A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M | 10-20-2011 |
20110236908 | TOTAL PLASMA FVII/FVIIA LEVELS AS INDICATORS OF PRE-ECLAMPSIA OF PREGNANT FEMALES - Raised total plasma FVII protein, including activated FVII (FVIIa) in pregnant females, compared with total plasma FVII protein in normal pregnancy, has been found to be an indicator of the pregnancy complication of pre-eclampsia. | 09-29-2011 |
20100303890 | COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES - Disclosed is a polymer having an affinity for corneal cells such that it can be used as a substrate for the growth of corneal cells, and so is suitable for use in a corneal bandage, especially in the form of a contact lens in which at least the cornea contacting surface is composed of the polymer. The substrate with an affinity for corneal cells is a copolymer comprising units -(A)- and -(B)- in which the units A are derived from aminoalkyl (alkyl)acrylates and the units B are derived from aryloxy, alkoxy or hydroxyalkyl (alkyl)acrylates, and (alkyl)acrylic acids. | 12-02-2010 |
20100286514 | CONTRAST ENHANCEMENT BETWEEN LINEAR AND NONLINEAR SCATTERERS - A method for creating an acoustic observation of a target volume, the method comprising the steps of transmitting a group of at least two acoustic pulses towards the target volume, receiving at least one detector an echo of the group scattered from the target volume, the echo having linear and nonlinear components, processing the scattered signal in such a way as to enhance at least part of the nonlinear component (and suppress the linear component) of the scattered signal in a signal P | 11-11-2010 |
20100249671 | System And Method For Assessing Lithotripsy - An apparatus, method and system for classifying a shockwave is described, particularly for use in an Extracorporeal Shockwave Lithotripsy (SWL) system. The method for classifying a shockwave generated and directed towards a stone in an extracorporeal shockwave lithotripsy treatment comprises receiving an acoustic signal at a passive unfocused acoustic sensor, determining whether at least one characteristic of the received acoustic emissions exceeds a respective pre-determined threshold value, and classifying the shockwave as effective or ineffective in dependence upon said determination. A method for predicting the outcome of an SWL treatment is also described. | 09-30-2010 |
20100241193 | Signal Processing In Devices, For Use With A Deficient Signal-Responsive Body Part - A cochlear implant provides electrical pulses to neurons and is configured to convert the excitation signal into a sparsified signal for electrically stimulating the neurons, thereby reducing the redundancy of the stimuli applied to the neurons. A signal analyser is configured to perform dimension reduction or factorisation of said excitation signal in the time domain or in the frequency domain followed by a sparse transform, the resulting relatively clean output signal providing the input to an inverse transformation step to create the sparsified signal. The dimension reduction or factorisation can be performed by principal component analysis (PCA), and the sparse transform can be performed by independent component analysis (ICA). | 09-23-2010 |
20100191639 | EXCHANGES FOR CREATING AND TRADING DERIVATIVE SECURITIES - A computer system ( | 07-29-2010 |
20100179317 | AMMOXIMATION PROCESS - A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms. | 07-15-2010 |
20100097060 | Apparatus for and method of determining an angle between an element and a magnetic field - An apparatus comprising a magnetic field generator for generating a magnetic field of a predetermined orientation, an element provided in the apparatus at a location that, in use, is within a region of the magnetic field having the predetermined orientation generated by the generator, and a device for determining an angle between the element and the magnetic field, the device comprising a Hall Effect sensor. | 04-22-2010 |
20100067000 | Raman spectroscopy - It has been discovered that specially structured metallic films containing voids can deliver a hugely enhanced surface enhanced Raman spectroscopy (SERS) effect. By selecting a particular size and geometry for the voids, metallic films can be provided which have an enhanced photon-to-plasmon conversion efficiency for incident radiation of a predetermined wavelength. Controllable surface-enhanced absorption and emission characteristics may thus be provided, which are useful for SERS and potentially also other optical spectrometry and filtering applications. With such a large Raman signal, the invention enables fast, compact and inexpensive Raman spectrometers to be provided opening up many new application possibilities. | 03-18-2010 |
20100024385 | PULSED PLASMA THRUSTER AND METHOD OF OPERATION THEREOF - A pulsed plasma thruster and method of operation are provided. The pulsed plasma thruster comprises solid propellant material. A main discharge source provides a pulsed discharge across the propellant material for ablating the propellant material to produce propellant plasma and accelerating the ablated propellant plasma, and an auxiliary discharge source accelerates late ablated propellant plasma without substantially further ablating the propellant material. | 02-04-2010 |
20090154869 | Tunable Filter Device Comprising a Waveguide Containing Bragg Grating, and a Planer Substrate - A tunable filter device ( | 06-18-2009 |
20080242836 | Convergent Solid Phase Peptide Synthesis By Reaction Of Two Fragments Bound To Solid Support - A process for preparing a peptide or protein by solid phase synthesis comprising combining a sequence including one or more amino acids obtainable by C-N synthesis linked to a first resin, with an amino acid sequence including one or more amino acid obtainable by N-C synthesis linked to a second resin so as to create a native peptide link between unprotected N and unprotected C terminals of said amino acid sequences, and optionally releasing the resulting peptide from one or more of the linked resins so as to combine with further N-C or C-N sequences or to release the desired peptide or protein sequence. | 10-02-2008 |
20080220056 | Treatment for liver disease - The present invention is based on the finding that the artificial induction of hepatic stellate cell (HSC) apoptosis in vivo can promote the resolution of liver fibrosis. Thus, the present invention provides methods for treating liver disease in a subject involving administration of an inducer of apoptosis which is capable of selectively inducing hepatic stellate cell apoptosis in the liver of the subject or of an agent which is capable of giving rise to such an inducer in the subject. In addition, the invention provides methods for treating liver fibrosis in a subject comprising the selective delivery of an inducer of apoptosis specifically to the hepatic stellate cells of the subject or of an agent which is capable of giving rise to an inducer of hepatic stellate cell apoptosis. | 09-11-2008 |
20080204747 | Multiwavelength Optical Sensors - An optical sensor comprises at least two planar Bragg gratings defined on a single substrate and arranged to receive light from a light source, each grating having a wavelength filtering response that varies with an effective modal index experienced by light propagating in the Bragg grating and a Bragg wavelength different to those of the other gratings, and at least one sample window overlying one or more of the gratings that can receive a sample of fluid that affects the effective modal index and response of the grating, the gratings filtering the light and outputting the filtered light for spectral analysis, from which the refractive index and related properties of the fluid can be determined. One or more of the gratings can be a reference grating used to compensate for temperature and other disturbances to the sensors. Gratings may have individual sample windows for testing separate fluid samples, or may share a common window so that a single fluid can be tested using several gratings. | 08-28-2008 |