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University of South Bohemia

University of South Bohemia Patent applications
Patent application numberTitlePublished
20090035755Yeast Strain And Screening Method For Identifying Inhibitors Of The Expression Of The Hexose Transporter Genes By A Positive Phenotype - The present invention provides screening procedures for identifying inhibitors of components of regulatory networks by a positive phenotype and modified yeast cell lines suitable for said screening. The screening procedures are especially suited to screen for substances that re-sensitize resistant pathogenic microorganisms or tumor cells by suspending the expression of resistance-relevant genes. The invention further provides methods for constructing said cell lines and their use in screening systems.02-05-2009