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UNIVERSITY OF NORTH TEXAS

UNIVERSITY OF NORTH TEXAS Patent applications
Patent application numberTitlePublished
20120104244PETROLEUM OIL ANALYSIS USING LIQUID NITROGEN COLD STAGE - LASER ABLATION- ICP MASS SPECTROMETRY - A novel application of a cold-stage coupled to a laser ablation-ICP-MS system is disclosed herein. The novel system of the present invention offers significant advantages over other systems employed for cooling samples prior to LA-ICP-MS analysis. The system discloses herein has multiple applications, including detection of one or more metal contaminants in an oil sample.05-03-2012
20120104243Silver and Silver Nanoparticle MALDI Matrix Utilizing Online Soft Landing Ion Mobillity - Silver nanoparticles as a sample matrix for Matrix Assisted Laser Desorption Ionization (MALDI) along with a novel method for nanoparticle development is described herein. The silver nanoparticles were generated from silver ions on the surface of a MALDI plate utilizing a Soft Landing Ion Mobility (SLIM) instrument. Upon interaction with the surface the incident silver ions were labile and aggregated into the nanoparticle structures in a time dependent fashion. Post landing analyses were completed by Time of Flight mass spectrometry (TOF), and of particular interest in the spectra were the elimination of low mass interference peaks that generally plague organic based matrices. The approach of the present invention significantly decreases sample preparation time and may lead to a preparation free MALDI source by soft landing a matrix directly on the sample surface.05-03-2012
20120085900NANOMANIPULATION COUPLED NANOSPRAY MASS SPECTROMETRY (NMS) - A coupled nanomanipulation and nanospray mass spectrometry (NMS) system for single cell, single organelle, and ultra-trace molecular analysis is disclosed herein. The system primarily comprises a bio-workstation coupled to a NMS. The bio-workstation primarily comprises of a nanomanipulator stage with a plurality of nano-positioners attached to a cabinet with a piezo voltage source and a pressure injector. The present invention further describes a fingerprint lift method that when coupled with the system disclosed herein can be used for retrieval and analysis of trace amounts of drug and explosive residues. The system described herein has been used in the areas of trace and document analysis within the forensic field, trace fiber analysis, and electrostatic lifts for illicit drugs, as well as document and painting analysis.04-12-2012
20120076832SYNTHESIS AND USE OF THERAPEUTIC METAL ION CONTAINING POLYMERIC PARTICLES - Therapeutic particles contain metal ions and are characterized by the use of unique ligand sets capable of making the metal ion complex soluble in biological media to induce selective toxicity in diseased cells. The particles may comprise a polymeric base particle, at least one pharmaceutically active metal ion, including metal ions from more than one metal element, a ligand that is covalently attached to the polymeric base particle and attached to the metal ion via a stimuli-responsive bond, and a cell targeting component. When the metal ion-containing particle enters a pre-defined environment, the ligands binding the metal to the particle are broken, triggering release of the free metal ion while the original ligands remain covalently bound to the particle.03-29-2012
20120065614POLYIONIC TRANSITIONAL METAL PHOSPHORESCENT COMPLEX/POLYMER HYBRID SYSTEMS FOR BIOIMAGING AND SENSING APPLICATIONS - A new technique to stabilize transition metal phosphors in a wide variety of stimuli-sensitive polymers and gels is disclosed herein. Other than stabilization in stimuli sensitive/biocompatible matrix some of these transition metal based phosphors are also shown to act as phosphorescent crosslinkers that physically or chemically crosslink polymeric chains to form micro/nanoparticles. The microspheres/nanospheres of the present invention show decreased size and photoluminescence enhancement with particularly high sensitization at physiological pH and temperature. The so formed phosphorescent micro/nanospheres are useful for biological or environmental applications including biological labeling, imaging, and optical sensing. The techniques in the present invention enable usage of imaging agents and sensors at very low concentrations and also minimize or eliminate the usage of toxic chemical crosslinkers typically used to synthesize polymeric micro/nanoparticles.03-15-2012
20120015166GRAPHENE/(MULTILAYER) BORON NITRIDE HETEROEPITAXY FOR ELECTRONIC DEVICE APPLICATIONS - Disclosed is a substrate-mediated assembly for graphene structures. According to an embodiment, long-range ordered, multilayer BN(111) films can be formed by atomic layer deposition (ALD) onto a substrate. The subject BN(111) films can then be used to order carbon atoms into a graphene sheet during a carbon deposition process.01-19-2012
20110269619Controlled Deposition of Metal and Metal Cluster Ions by Surface Field Patterning in Soft-Landing Devices - A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube and a split-ring ion optic for the isolation of selected ions. The drift tube allows for the separation and thermalization of ions formed after laser ablation through collisions with an inert bath gas that allow the ions to be landed at energies below 1 eV onto substrates. The split-ring ion optic is capable of directing ions toward the detector or a landing substrate for selected components. The inventors further performed atomic force microscopy (AFM) and drift tube measurements to characterize the performance characteristics of the instrument.11-03-2011
20110260145ORGANIC LIGHT-EMITTING DIODES FROM HOMOLEPTIC SQUARE PLANAR COMPLEXES - Homoleptic square planar complexes [M(NΛN)10-27-2011
20110190287Thrombocyte Inhibition Via Vivo-Morpholino Knockdown of Alpha IIB - Novel compounds comprising a guanidine-rich head covalently coupled to one or more oligonucleotide antisense sequences which are useful to modulate blood coagulation by affecting the expression of integrin αIIb or β3 are described herein. This invention also includes pharmaceutical compositions containing these compounds, with or without other therapeutic agents, and to methods of using these compounds as inhibitor of platelet aggregation, as thrombolytics, and/or for the treatment of other thromboembolic disorders. Vivo-MOs, which include eight guanidine groups dendrimerically arranged in the guanidine-rich head and two synthetic antisense morpholino oligonucleotides, are representative compounds of the present invention.08-04-2011
20110061378Liquid Cooled Stirling Engine with a Segmented Rotary Displacer - The present invention provides a Stirling engine employing a segmented, rotary displacer for producing mechanical energy from a heat source. The engine includes a rotor shaft rotatably positioned in the interior toroidal cavity with a segmented displacer mounted to the rotor shaft within the interior toroidal cavity.03-17-2011
20110043356SYSTEM, METHOD AND APPARATUS FOR ENERGIZING VEHICLE BRAKE LIGHTS - The present invention provides system, method and apparatus for energizing one or more brake lights on a vehicle without an operator of the vehicle applying a brake of the vehicle by determining an acceleration of the vehicle, energizing the brake lights on the vehicle whenever the acceleration of the vehicle equals or exceeds a braking threshold, and deenergizing the brake lights on the vehicle whenever: (a) the brake lights are energized, (b) the acceleration of the vehicle is less than the braking threshold, (c) a specified period of time has elapsed since the brake lights were energized, and (d) the operator is not applying the brake of the vehicle.02-24-2011
20100285210MULTIFUNCTIONAL MICROPIPETTE BIOLOGICAL SENSOR - The fabrication and use of a multifunctional micropipette biological sensor for in-situ detection of temperature changes, ion conductivity, and light is described herein.11-11-2010
20100261814Synthesis of columnar hydrogel colloidal crystals in water-organic solvent mixture - The compositions of hydrogel colloidal crystals are made from mixing an aqueous suspension of poly-N-isopropylacrylamide (“PNIPAM”)-co-allylamine microgels with dichloromethane, forming a PNIPAM-co-allylamine/dichloromethane mixture. The PNIPAM-co-allylamine/dichloromethane mixture is incubated for a period of time at a given temperature, forming the colloidal crystal material. The colloidal crystals can be stabilized by diffusing a glutaric dialdehyde solution into the colloidal crystal material. The concentration of polymer matrix microgels can determine the orientation of random or columnar crystals.10-14-2010
20100172997GOLD, SILVER, AND COPPER NANOPARTICLES STABILIZED IN BIOCOMPATIBLE AQUEOUS MEDIA - The present invention includes metal nanoparticles composition and methods of making and using the same by converting a metal (I) to a metal (0) and forming one or more metal nanoparticles from the metal (0). The one or more metal nanoparticles are stabilized with one or more biocompatible stabilizers to prevent agglomeration and make them amenable for biomedical applications.07-08-2010
20100168024DIRECT UTILIZATION OF PLASMA PROTEINS FOR THE IN VIVO ASSEMBLY OF PROTEIN-DRUG/IMAGING AGENT CONJUGATES, NANOCARRIERS AND COATINGS FOR BIOMATERIALS - The present invention includes compositions and methods for making and using a drug conjugated to a peptide or protein that binds specifically to a ligand in vivo, wherein the conjugate binds to its ligand in vivo and increases the half-life of the drug.07-01-2010
20100163724APPLICATIONS OF HYDROGEN GAS GETTERS IN MASS SPECTROMETRY - The present invention is an electrically controlled gettered pump assembly to entrain and fully release hydrogen gas to regulate the pressure and buffer the ions in an ion trap mass spectrometer and other portable analytical instruments. In addition to the gettered pump assembly, the present invention also incorporates a microvalve between the different chambers to release and control the hydrogen content. Hydrogen gas regulates the pressure in mass spectrometers and also acts as a buffering gas to prevent the ions from escaping the trap.07-01-2010
20100145678Method, System and Apparatus for Automatic Keyword Extraction - The present invention provides a method and a system for automatic keyword extraction based on supervised or unsupervised machine learning techniques. Novel linguistically-motivated machine learning features are introduced, including discourse comprehension features based on construction integration theory, numeric features making use of syntactic part-of-speech patterns, and probabilistic features based on analysis of online encyclopedia annotations. The improved keyword extraction methods are combined with word sense disambiguation into a system for automatically generating annotations to enrich text with links to encyclopedic knowledge.06-10-2010
20100076105MONODISPERSE THERMO-RESPONSIVE MICROGELS OF POLY(ETHYLENE GLYCOL) ANALOGUE-BASED BIOPOLYMERS, THEIR MANUFACTURE, AND THEIR APPLICATIONS - Composition, processes, techniques, and apparatus for synthesizing monodisperse microgels based on poly(ethylene glycol) (PEG) derivative polymers by using precipitation polymerization. These microgels are hydrophilic and have the adjustable volume phase transition temperature in aqueous environment. Microgels can be added with various functional groups. These microgels in water can self-assemble into various phases, including a crystalline phase. Hydrogel films with iridescent colors were formed using these microgels as crosslinkers to connect poly(ethylene glycol) chains. The colors of these hydrogel films change with changes of environment such temperature, pH, salt concentration, etc.03-25-2010
20100052852Methods and devices for enrollment and verification of biometric information in identification documents - Methods and devices for the secure encryption, enrollment, verification, and decryption of biometric and biographical identification information. The unique sequence of steps and the use of a combination of visible watermarking, invisible-fragile watermarking decoding, invisible-robust extraction, and decryption watermarking and encryption provides multiple layers of protection with four biometric based keys and makes it practically impossible for the information to be tampered with.03-04-2010
20090176932Halogen containing epoxy compositions and their preparation - One aspect of the current invention is a halogen containing epoxy composition and a method of producing the same. A functional halogen group, fluorine in one case, is incorporated into an epoxy coating by using a functionalized amine curing agent in small amounts. Functionalized amine curing agents are cheaper and easier to produce from small amine precursors when compared to the cost and complexity of functionalizing bulky epoxy resins. Amine curing agents are incorporated into a cured epoxy network. However, many functional groups will affect the reactivity of the curing reaction due to electronegativity effects. By using small amounts of functionalized amines with a large amount of non-functionalized agent, the effect is small and in the case of migration, it can be advantageous for tribological, mechanical and other properties of epoxies and epoxy-containing materials. Additionally, in stratified coatings, it is advantageous to use smaller functionalized amine molecules that can migrate more quickly into the composition before the composition becomes fully cured.07-09-2009
20090132825APPARATUS AND METHOD FOR TRANSMITTING SECURE AND/OR COPYRIGHTED DIGITAL VIDEO BROADCASTING DATA OVER INTERNET PROTOCOL NETWORK - A content distribution method for video copyright authentication and security comprising the steps of invisibly watermarking digital video data input from a video data source to create watermarked data; encrypting the watermarked digital video data using an encryption key to create encrypted video data; sending the encrypted watermarked digital data and a decryption key to a distribution network; decrypting the encrypted watermarked digital data to generate video data and adding visible watermarking data to the video data to generate visibly encrypted watermarked data compressing the visibly encrypted watermarked data to create compressed data; sending said compressed data and to an end user receiver; decompressing the compressed data at the receiver to generate decompressed data; and displaying the decompressed data to an end user.05-21-2009
20080279754Induced electrical property changes in single walled carbon nanotubes by electromagnetic radiation - In the apparatus and process of the present invention, it is possible to fabricate CNTs with specific diameters and morphologies. The morphology selection can yield samples of pre-selected diameter configurations making it possible to take a sample of SWNTs produced by any synthesis technique and induce a morphology change that causes the sample to be either all conductive, all narrow band gap semiconductive or wide band gap semiconductive, within a given nanotube rope.11-13-2008

Patent applications by UNIVERSITY OF NORTH TEXAS