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University of North Carolina at Chapel Hill, a North Carolina corporation

University of North Carolina at Chapel Hill, a North Carolina corporation Patent applications
Patent application numberTitlePublished
20110105740SOLUBLE TNF RECEPTORS AND THEIR USE IN TREATMENT OF DISEASE - The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular, the proteins are mammalian TNFRs that lack exon 7 and which can bind TNF and can act as a TNF antagonist.05-05-2011