UNIVERSITY OF MELBOURNE Patent applications |
Patent application number | Title | Published |
20140179540 | MODIFYING PROTEINS (GPCR), LIGANDS, AND NANOPORE SURFACES TO ALLOW THE DETECTION OF CREATE BINDING-INDUCED MOLECULAR CHANGES OF PROTEIN-LIGAND COMPLEXES WITH NANOCHANNEL TRANSLOCATION - A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event. | 06-26-2014 |
20130183377 | SYNTHETIC IMMUNOGEN USEFUL FOR GENERATING LONG LASTING IMMUNITY AND PROTECTION AGAINST PATHOGENS - The present invention relates to a synthetic immunogen represented by the general formula 1, useful for generating long lasting protective immunity against various intracellular pathogens which are the causative agents of tuberculosis, leishmaniasis, AIDS, trypanosomiasis, malaria and also allergy, cancer and a process for the preparation thereof. The developed immunogen is able to circumvent HLA restriction in humans and livestock. The invention further relates to a vaccine comprising the said immunogen for generating enduring protective immunity against various diseases. The said vaccine is targeted against intracellular pathogens, more particularly the pathogen | 07-18-2013 |
20090324642 | METHOD OF ELICTING OR INDUCING AN IMMUNE RESPONSE - A method for eliciting or inducing an immune response in a human or animal subject, comprises administering to said subject a composition comprising an antigen and an adjuvant, wherein the composition is administered to the subject by the intra-lung route. | 12-31-2009 |
20080286590 | Ceramic and Metallic Components and Methods for Their Production from Flexible Gelled Materials - According to one embodiment of the present invention there is provided a method of producing a sheet of flexible gelled ceramic and/or metallic containing material, comprising the steps of: (a) combining water, ceramic and/or metallic powder, polymer, plasticiser, water soluble cross-linking agent precursor and optional further components to produce a mixture; (b) applying the mixture to a suitable substrate to form a layer of desired dimensions; (c) exposing the layer to conditions suitable for cross-linking to occur. According to another embodiment of the present invention there is provided a method of producing a ceramic and/or metallic component comprising the steps of: (a) combining water, ceramic and/or metallic powder, polymer, plasticiser, water soluble cross-linking agent precursor and optional further components to produce a mixture; (b) applying the mixture to a suitable substrate to form a layer of desired dimensions; (c) exposing the layer to conditions suitable for cross-linking to occur; (d) optionally removing from the substrate a flexible gelled material obtained following step (c); (e) optionally drying the flexible gelled material; (f) processing the flexible gelled material to desired shape; (g) firing flexible gelled material of desired shape to produce a ceramic and/or metallic component. Preferably the ceramic and/or metallic component is a component of a fuel cell, photo-voltaic cell, multi-layered capacitor or other micro-electronic component, prosthetic or surgical devices, refractory equipment, fibre optic device or transmission equipment. | 11-20-2008 |