| UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION Patent applications |
| Patent application number | Title | Published |
|---|
| 20120058933 | SYNTHETIC PEPTIDES AND PEPTIDE MIMETICS - The present invention provides Parotid Secretory Protein peptides, nucleic acids encoding the peptides, and methods of using the peptides, and methods of screening GL13 mimetics. | 03-08-2012 |
| 20110319351 | TREATING CANCER WITH CARDIAC GLYCOSIDES - The invention provides methods to treat cancer with cardiac glycosides. | 12-29-2011 |
| 20110077393 | METHODS OF SYNTHESIS AND PURIFICATION BY USE OF A SOLID SUPPORT - Disclosed herein are novel methods of using polymeric adsorbent resin for chemical synthesis and the purification of product therefrom. Also disclosed herein is a novel method of using silica gel for the combination of chemical reaction and chromatography into a single step. The methods disclosed herein increase the efficiency of chemical synthesis processes. Accordingly, the utility of the methods disclosed herein includes the ability to automate chemical synthesis and purification of the resulting products. | 03-31-2011 |
| 20110059451 | DETECTING FETAL CHROMOSOMAL ABNORMALITIES USING TANDEM SINGLE NUCLEOTIDE POLYMORPHISMS - The invention provides tandem single nucleotide polymorphisms and methods for their use, for example, in diagnosing Down Syndrome. | 03-10-2011 |
| 20100308791 | SINGLE ELEMENT THREE TERMINAL PIEZORESISTIVE PRESSURE SENSOR - Embodiments of the invention provide for three-terminal pressure sensors (“3-TPS”), a method of measuring a pressure with a 3-TPS, and a method of manufacturing a 3-TPS. In some embodiments, the 3-TPS includes a semiconducting layer with cavity and a 3-TPS element having at least one piezoresistive layer overlapping at least a portion of the cavity and oriented at an angle selected to provide a desired sensitivity for the 3-TPS. The method of measuring a pressure with a 3-TPS is performed with a 3-TPS that includes an input terminal, first and second output terminals, and a 3-TPS element, the 3-TPS element overlapping at least a portion of a cavity at a predetermined angle. The method comprises providing an input signal to the input terminal of the 3-TPS, determining a difference between two output signals from the respective output terminals of the 3-TPS, and correlating the determined difference to a pressure. | 12-09-2010 |
| 20100184044 | Detecting Genetic Abnormalities - The present invention is directed to compositions and methods for detecting genetic abnormalities. The present invention encompasses methods and compositions for comparing alleles in a sample containing both maternal and fetal nucleic acids in order to identify genetic abnormalities. | 07-22-2010 |
| 20100184043 | Detecting Genetic Abnormalities - The present invention is directed to compositions and methods for detecting genetic abnormalities. The present invention encompasses methods and compositions for comparing alleles in a sample containing both maternal and fetal nucleic acids in order to identify genetic abnormalities. | 07-22-2010 |
| 20090247466 | NEUROPROTECTIVE INTEGRIN-BINDING PEPTIDE AND ANGIOPOIETIN-1 TREATMENTS - The present invention provides therapeutic compositions, kits and methods for treating nervous system injury in a mammal. Certain methods include administering to a mammal in need of such therapy an effective amount of angiopoietin-1 (Ang-1), or a functional analog thereof. Certain methods include administering a peptide having 4 to 20 amino acids that comprises an YVRL (SEQ ID NO:1) motif that may have activity at the αvβ3 or α5β1 integrin receptor, such as C-16, or a compound that is an agonist at the αvβ3 and/or α5β1 integrin receptor, which administration may be in combination with administration of Ang-1, or a functional analog thereof. | 10-01-2009 |
| 20090214603 | SYNTHETIC PEPTIDES - The present invention provides streptococcal SspB Adherence Region (BAR) peptides, nucleic acids encoding the BAR peptides, and methods of using the BAR peptides, and methods of screening BAR peptide mimetics. | 08-27-2009 |
| 20090162439 | SILK FIBROIN COATING - The present invention is directed to compositions and methods for preventing or inhibiting biofilm formation on a solid substrate comprising an antimicrobial agent and a biofilm-degrading enzyme embedded in a matrix material. | 06-25-2009 |
| 20090023700 | NEUROPROTECTIVE TREATMENTS - The present invention provides a therapeutic method for treating traumatic neural injury or a degenerative disorder in a mammal by administering a neuroprotective compound, wherein the neuroprotective compound is a peroxovanadium compound, a peroxovandium derivative, or a compound with inhibitory activity of protein tyrosine phosphatases. | 01-22-2009 |
| 20090018088 | TREATING CANCER WITH CARDIAC GLYCOSIDES - The invention provides methods to treat cancer with cardiac glycosides. | 01-15-2009 |
