| University of Georgia Research Foundation, Inc. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120129928 | Chlorine-Free Liquid Microbicide Treatment - The combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds. Accordingly, this surprising synergy allows the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial counts in liquids, including, but not limited to, water and other beverages, especially those having a pH value less than about 7.0 by a factor between 10 | 05-24-2012 |
| 20120121679 | VIRICIDAL AND MICROBICIDAL COMPOSITIONS AND USES THEREOF - The present disclosure encompasses compositions comprising a surfactant, and an acid such as, but not limited to, levulinic acid, that together have a synergistic effect in reducing the viability of a virus population compared to the efficacy of the individual compounds. This synergy allows the formulation of compositions where the active agents (including an acid and a surfactant) are present at concentrations effective to inactivate viruses on surfaces, including human skin. The viricidal compositions disclosed herein are efficacious without damaging the surface to which they may be applied, or even altering the organoleptic properties of a treated food substance. The viricidal compositions and wipes containing such compositions are suitable for sanitizing any surface suspected of having a viral load thereon, or where it is desirable to ensure that a viral load is as low as possible. | 05-17-2012 |
| 20120110710 | PUNICA GRANATUM PLANT NAMED 'ORANGE BLOSSOM SPECIAL' - A new and distinct cultivar of | 05-03-2012 |
| 20120094347 | METHODS AND COMPOSITIONS FOR DEGRADING PECTIN - The present invention provides enriched polynucleotides, and enriched polypeptides having pectinase activity. The present invention also includes methods of using the polynucleotides and polypeptides described herein. For instance, the methods include producing a metabolic product, such as ethanol. | 04-19-2012 |
| 20120079764 | METHODS AND COMPOSITIONS USING FUNGAL LACCASES TO REDUCE TURF THATCH - The present disclosure describes methods and compositions for reducing turf thatch and/or preventing turf thatch buildup. | 04-05-2012 |
| 20120071553 | CHLORINE-FREE WATER TREATMENT - A combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds, allowing the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial and fungal counts in liquids, including, but not limited to, water and other beverages, without altering the organoleptic properties of the treated food substance. The active agents are FDA-approved as food additives, and the treated beverages can be any aqueous-based beverage consumable by humans or animals. The levulinic acid-SDS combination is also suitable for reducing or eliminating the microbial population on the surfaces of water and beverage containers, and the machinery and facilities for the bottling of liquids. | 03-22-2012 |
| 20120070490 | ANTI-TRYPANOSOMAL PEPTIDES AND USES THEREOF - The present invention provides methods of killing, inhibiting the growth, and/or inhibiting the reproduction of kinetoplastid protozoan with hydrophobic signal sequence peptides and compositions including such hydrophobic signal sequence peptides. | 03-22-2012 |
| 20120059145 | STABILIZED BIOACTIVE PEPTIDES AND METHODS OF IDENTIFICATION, SYNTHESIS, AND USE - An intracellular selection system allows screening for peptide bioactivity and stability. Randomized recombinant peptides are screened for bioactivity in a tightly regulated expression system, preferably derived from the wild-type lac operon. Bioactive peptides thus identified are inherently protease- and peptidase-resistant. Also provided are bioactive peptides stabilized by a stabilizing group at the N-terminus, the C-terminus, or both. The stabilizing group can be a small stable protein, such as the Rop protein, glutathione sulfotransferase, thioredoxin, maltose binding protein, or glutathione reductase, an α-helical moiety, or one or more proline residues. | 03-08-2012 |
| 20120058960 | FEEDBACK PRODRUG - Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme. | 03-08-2012 |
| 20120040011 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 02-16-2012 |
| 20120039984 | GLYCOPEPTIDE AND USES THEREOF - A glycolipopeptide comprising a carbohydrate component, a peptide component and a lipid component, for use as a therapeutic or prophylactic vaccine. Also provided are monoclonal and polyclonal antibodies that recognize the glycolipopeptide of the invention, as well as uses thereof. | 02-16-2012 |
| 20120021005 | MYCOPLASMA GALLISEPTICUM FORMULATION - The present invention provides a formulation that prevents virulent | 01-26-2012 |
| 20120014962 | METHOD OF INHIBITING FIBROGENESIS AND TREATING FIBROTIC DISEASE - The present invention relates to the discovery of an epigenetic relay pathway that controls hepatic stellate cell activation and the wound-healing response in fibrogenesis, including fibrogenesis of the injured liver. Methods of inhibiting fibrogenesis, including liver fibrogenesis and secondary disease states and conditions thereof, and in treating liver damage, including cirrhosis of the liver (which may be caused by viruses or chemicals, including alcohol), are aspects of the present invention. The methods utilize certain nucleoside compounds and/or antibodies which are optionally conjugated. Pharmaceutical compositions represent additional aspects of the invention. | 01-19-2012 |
| 20110305672 | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME - The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells. | 12-15-2011 |
| 20110296572 | Lagerstroemia plant named 'PIILAG-III' - A new and distinct cultivar of | 12-01-2011 |
| 20110296570 | Lagerstroemia plant named 'PIILAG-II' - A new and distinct cultivar of | 12-01-2011 |
| 20110284798 | WHITE PHOSPHORS, METHODS OF MAKING WHITE PHOSPHORS, WHITE LIGHT EMITTING LEDS, METHODS OF MAKING WHITE LIGHT EMITTING LEDS, AND LIGHT BULB STRUCTURES - Phosphor compositions, white phosphor compositions, methods of making white phosphor compositions, tinted white phosphor compositions, methods of making tinted white phosphor compositions, LEDs, methods of making LEDs, light bulb structures, paints including phosphor compositions, polymer compositions including phosphor compositions, ceramics including phosphor compositions, and the like are provided. | 11-24-2011 |
| 20110280807 | Methods and Models for Stress-Induced Analgesia - The invention disclosed relates to methods and models for enhancing stress-induced analgesia through non-opioid mechanisms. | 11-17-2011 |
| 20110263487 | Plant Production and Delivery System for Recombinant Proteins as Protein-Flour or Protein-Oil Compositions - The present invention relates to a plant flour material comprising a ground, dried plant material, wherein the plant material contains a recombinant protein comprises a bactericidal or an insecticidal protein toxin, or combinations thereof. The present invention further relates to a seed oil body composition comprising a seed oil body fusion, said oil body fusion comprising an oil body protein fused to a recombinant protein comprising a bactericidal or an insecticidal protein toxin. The present invention provides for a method of abating or controlling the population of mosquitoes comprising administering to a water source suspected of containing mosquito larvae an effective amount of seed oil body preparation comprising one or more Bti toxins, optionally in combination with one or more BtBs. Additionally, the present invention provides for a method of controlling or abating a pathogenic microbial population comprising administering to an insect population, which serves as a host for the pathogenic microbial population, a recombinant plant material containing a recombinant protein comprising an bactericidal protein toxin. | 10-27-2011 |
| 20110217739 | CAS6 POLYPEPTIDES AND METHODS OF USE - Provided herein are methods for cleaving a target RNA polynucleotide. The target RNA polynucleotide includes a Cas6 recognition domain and a cleavage site, and may be based on a repeat from a CRISPR locus. The methods may be practiced in vivo or in vitro. Also provided are polypeptides that have Cas6 endoribonuclease activity in the presence of a target RNA polynucleotide, and methods for using the polypeptides. | 09-08-2011 |
| 20110189776 | PROKARYOTIC RNAi-LIKE SYSTEM AND METHODS OF USE - Provided herein are methods for inactivating a target polynucleotide. The methods use a psiRNA having a 5′ region and a 3′ region. The 5′ region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer. The 3′ region is substantially complementary to a portion of the target polynucleotide. The methods may be practiced in a prokaryotic microbe or in vitro. Also provided are polypeptides that have endonuclease activity in the presence of a psiRNA and a target polynucleotide, and methods for using the polypeptides. | 08-04-2011 |
| 20110111473 | YEAST CELLS AND METHODS FOR INCREASING ETHANOL PRODUCTION - Provided herein are methods for producing ethanol using yeast to ferment pretreated solid lignocellulosic materials such as pretreated solid lignocellulosic materials obtained from softwoods like pine. The pretreated solid lignocellulosic material is present at a concentration of at least 12% solids, and at least 30 grams ethanol per liter, preferably at least 40 grams ethanol per liter, are produced within 48 hours. In some aspects, the pretreated solid lignocellulosic material is not detoxified prior to the fermentation. Also provided herein are yeast that ferment a composition that includes pretreated solid lignocellulosic material at a concentration of at least 12% solids to yield at least 30 grams ethanol per liter, preferably at least 40 grams ethanol per liter, in 48 hours. Further provided herein are methods for acclimatizing yeast. | 05-12-2011 |
| 20110091945 | METHODS OF INCREASING BIOMASS PRODUCTIVITY, LIPID INDUCTION, AND CONTROLLING METABOLITES IN ALGAE FOR PRODUCTION OF BIOFUELS USING BIOCHEMICAL STIMULANTS - The present disclosure provides methods of enhancing the biofuel potential of an algal culture, the ability of an algal culture to provide a biofuel such as a lipid or to be processed to a biofuel, the method comprising: contacting an algal culture with a composition selected to enhance the biofuel potential of an algal culture; and allowing the algal culture to incubate to the point where the potential of the algal culture to provide a biofuel product or be processed to a biofuel product is enhanced compared to when the algal culture is not in contact with the composition. The selected algal species can be a species of a genus selected from the group consisting of: | 04-21-2011 |
| 20110033875 | GLYCOPROTEIN CANCER BIOMARKER - The invention relates to glycoproteins having a cancer-specific glycoform. Cancer-specific glycoforms are useful in diagnostics and therapeutics. | 02-10-2011 |
| 20110020875 | HYDROGENASE POLYPEPTIDE AND METHODS OF USE - Provided herein are polypeptides having hydrogenase activity. The polypeptide may be multimeric, and may have hydrogenase activity of at least 0.05 micromoles H | 01-27-2011 |
| 20100323909 | DIAGNOSTIC ASSAY FOR TRYPANOSOMA CRUZI INFECTION - A sensitive, multicomponent diagnostic test for infection with | 12-23-2010 |
| 20100304450 | MICROBIAL PRODUCTION OF PYRUVATE AND PYRUVATE DERIVATIVES - Microbial production of pyruvate and metabolites derived from pyruvate in cells exhibiting reduced pyruvate dehydrogenase activity compared to wild-type cells. Acetate and glucose are supplied as a carbon sources. | 12-02-2010 |
| 20100298252 | METHODS AND COMPOSITIONS FOR OPHTHALMIC TREATMENT OF FUNGAL AND BACTERIAL INFECTIONS - The present invention provides methods and compositions for use in the methods for contacting an eye of a patient with an effective amount of therapeutic composition comprising a pharmaceutically acceptable chelating agent, a pharmaceutically acceptable pH buffering agent, and an antimicrobial agent. | 11-25-2010 |
| 20100297609 | VIVO ISOTOPIC LABELING METHOD FOR QUANTITATIVE GLYCOMICS - The present invention relates to a method of isotopically labeling glycans and in facilitating high throughput quantitative/comparative analysis of glycomic compositions of biological cells. The method is applicable inter alia for identifying differentiated cells and their glycomic characteristics, differentiation conditions, disease and/or therapeutic progression, diagnosing disease states, determining drug activity, establishing manufacturing efficiencies and for determining the half-life of glycans in cells. | 11-25-2010 |
| 20100297250 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS - 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate. | 11-25-2010 |
| 20100297173 | PROPHYLACTIC AND THERAPEUTIC IMMUNIZATION AGAINST PROTOZOAN INFECTION AND DISEASE - Polypeptide and polynucleotide vaccines effective to treat or prevent infection of a mammal, such as a dog, a cat, or a human, by a protozoan. Methods of treatment and prevention are also provided, including therapeutic administration of the vaccine to an infected mammal to prevent progression of infection to a chronic debilitating disease state. Preferred embodiments of the polynucleotide vaccine contain nucleotide coding regions that encode polypeptides that are surface-associated or secreted by | 11-25-2010 |
| 20100279287 | COMPOSITIONS AND METHODS USEFUL FOR SITE-DIRECTED RECOMBINATION IN PLANTS - This invention relates generally to useful compositions and methods related to plant site-directed recombination. In particular, the invention relates to novel nucleic acid sequences unique to a portion of the sorghum NBS-LRR region, as well as vectors, seeds, plant parts and plants comprising these sequences. Methods to investigate recombination co-factors, and methods to investigate potential herbicides are within the scope. This invention also relates to fungal pathogens of sorghum, particularly | 11-04-2010 |
| 20100278864 | Rabies Vaccine - An attenuated rabies virus for use as a live vaccine. The attenuated rabies virus expresses an immune factor that enhances immune response upon administration of the live vaccine. | 11-04-2010 |
| 20100266674 | L-ODDC PRODRUGS FOR CANCER - The main drawback in the use of most nucleoside anticancer agents originates from their hydrophilic nature, of which property requires a high and frequent dosage for an intravenous administration. Unlike other nucleoside anti-tumor agents, troxacitabine appears to predominantly enter tumor cells by passive diffusion rather then by using nucleoside transporters, although this may be model dependent. Accordingly, in the present work, a small library of twenty troxacitabine prodrugs has been synthesized using a parallel approach in order to evaluate the relationship between the lipophilicity of the prodrugs and their antitumor activity. Biological evaluation of the prodrugs on two non-small cell lung cancer cell lines (A549 and SW1573) and in pancreatic cell lines clearly showed better antitumor activity than that of troxacitabine, with IC | 10-21-2010 |
| 20100218290 | SOUTHERN HIGHBUSH BLUEBERRY PLANT NAMED 'TH-682' - The new variety ‘TH-682’ is provided. The new and distinct variety ripens early compared to rabbiteye varieties generally available to homeowners and produces an abundance of attractive, light blue fruit that are generally large and have good flavor. The plant of the new variety ‘TH-682’ is vigorous, produces an attractive fall foliage color and is estimated to have a chilling requirement of approximately 500 to 550 hours below approximately 45° F. The asexually reproduced variety is reliably propagated vegetatively. | 08-26-2010 |
| 20100212054 | Pennisetum 'Tift-23' - The new variety | 08-19-2010 |
| 20100212053 | PENNISETUM PLANT NAMED 'TIFT-17' - The new variety | 08-19-2010 |
| 20100196881 | REVERSE RESTRICTION FRAGMENT LENGTH POLYMORPHISM ASSAY AND USES THEREOF - The present invention presents a Reverse Restriction Fragment Length Polymorphism (RRFLP) method for the detection of the presence of an informative restriction enzyme site in a nucleotide sequence. The method includes digesting a sample with the informative restriction enzyme; performing polymerase chain reaction (PCR) on the digested sample with an oligonucleotide primer pair that flanks the informative restriction enzyme site; determining the Ct value of the sample; comparing the Ct value of the sample to the Ct value from a control sample; and calculating a ΔCt value, wherein a ΔCt value is the Ct value of the sample minus the Ct value of a control; and wherein a ΔCt value ≧+1 indicates that the informative restriction enzyme sites is present in the nucleotide sequence. The present invention includes the application of the RRFLP method for detection of the infectious laryngotracheitis virus (ILTV). | 08-05-2010 |
| 20100160207 | Feedback Prodrug - Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme. | 06-24-2010 |
| 20100144664 | CARBOCYCLIC COMPOUNDS AND METHODS FOR TREATING EMERGING DISEASE, INCLUDING INFLUENZA AND VENEZUELA EQUINE ENCEPHALITIS VIRUS - The present invention relates to the use of carbodine and 5-F carbodine and analogs thereof for use in the treatment or prophylaxis of influenza, in particular the H5N1 strain of Avian Influenza A virus or “bird flu” strain of influenza as well as the treatment or prophylaxis of Venezuela equine encephalitis virus or VEE. | 06-10-2010 |
| 20100122369 | Switchgrass Cultivar EG1102 - A switchgrass cultivar designated EG1102 is disclosed. The invention relates to the seeds of switchgrass cultivar EG1102, to the plants of switchgrass EG1102, to plant parts of switchgrass cultivar EG1102 and to methods for producing a switchgrass plant produced by crossing switchgrass cultivar EG1102 with itself or with another switchgrass variety. The invention also relates to methods for producing a switchgrass plant containing in its genetic material one or more transgenes and to the transgenic switchgrass plants and plant parts produced by those methods. This invention also relates to switchgrass cultivars or breeding cultivars and plant parts derived from switchgrass variety EG1102, to methods for producing other switchgrass cultivars, lines or plant parts derived from switchgrass cultivar EG1102 and to the switchgrass plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid switchgrass seeds, plants and plant parts produced by crossing the cultivar EG1102 with another switchgrass cultivar. | 05-13-2010 |
| 20100122368 | Switchgrass Cultivar EG1101 - A switchgrass cultivar designated EG1101 is disclosed. Also disclosed are seeds of switchgrass cultivar EG1101, plants of switchgrass EG1101, plant parts of switchgrass cultivar EG1101 and methods for producing a switchgrass plant produced by crossing switchgrass cultivar EG1101 with itself or with another switchgrass variety. Methods are also described for producing a switchgrass plant containing in its genetic material one or more transgenes and to the transgenic switchgrass plants and plant parts produced by those methods. Switchgrass cultivars or breeding cultivars and plant parts derived from switchgrass variety EG1101, methods for producing other switchgrass cultivars, lines or plant parts derived from switchgrass cultivar EG1101 and the switchgrass plants, varieties, and their parts derived from use of those methods are described herein. Hybrid switchgrass seeds, plants and plant parts produced by crossing the cultivar EG1101 with another switchgrass cultivar are also described. | 05-13-2010 |
| 20100068753 | Biotin-facilitated transport in gram negative bacteria - Biotinylation of compounds such as peptides and peptidomimetics facilitates illicit transport of the compounds into Gram negative bacteria. | 03-18-2010 |
| 20100055131 | REOVIRUS COMPOSITIONS AND METHODS OF USE - The present invention relates to novel strains of avian reovirus that were isolated from severe cases of Runting Stunting Syndrome in young broiler chickens in southeast United States. The invention is directed to avian reoviruses that impair digestion in poultry, diagnostic assays using nucleotide- or amino acid-specific components of such viruses, and to vaccines that protect chickens from disease caused by such viruses. Nucleotide sequences for the SI gene, encoding the sigma C minor outer capsid protein, were amplified, and the nucleotide and predicted amino acid sequences were compared with sequences from other recently isolated reovirus field isolates and vaccine strains. Antigenic and molecular characterization of the newly isolated reoviruses revealed a lack of homogeneity with current U.S. isolates, with less than 60% percent amino acid similarity across the sigma C protein. Sequence comparisons with previously reported malabsorption isolates from Europe and Asia revealed a higher amino acid similarity, approaching 80%. | 03-04-2010 |
| 20100041895 | Synthesis and Stabilization of Neutral Compounds with Homonuclear Bonds - The present invention is directed to the synthesis and stabilization of neutral molecules containing homonuclear single or multiple bonds, methods of preparation, and uses thereof. | 02-18-2010 |
| 20090324550 | COMPOSITION AND METHOD FOR INHIBITION OF MICROORGANISMS - A composition and method for the inhibition of microorganisms. | 12-31-2009 |
| 20090313733 | INDIAN HAWTHORN PLANT NAMED 'RUTRHAPH1' - A new and distinct cultivar of hawthorn, | 12-17-2009 |
| 20090311747 | VECTORS AND METHODS FOR HIGH THROUGHPUT CO-EXPRESSIONS - The present invention includes vectors and methods for high throughput co-expression. | 12-17-2009 |
| 20090212055 | Litter Receptacle - A litter receptacle system, including: a support frame; a container for receiving and storing litter; a coupler; and a retention device; wherein the coupler rotatably couples the container to the support frame; the retention device is in communication with the support frame and the container; and the retention device is operable to releasably secure the container to the support frame, and a method of using the same. | 08-27-2009 |
| 20090208533 | NEISSERIA MENINGITIDIS SEROGROUP A CAPSULAR POLYSACCHARIDE ACETYLTRANSFERASE, METHODS AND COMPOSITIONS - Provided are methods for recombinant production of an O-acetyltransferase and methods for acetylating capsular polysaccharides, especially those of a Serogroup A | 08-20-2009 |
| 20090151033 | HYDRANGEA MACROPHYLLA PLANT NAMED 'PIIHM-I' - A new and distinct cultivar of | 06-11-2009 |
| 20090060266 | Methods and Systems for Analyzing Ratiometric Data - Systems and methods for analyzing ratiometric data, e.g., ratiometric image data such as fluorescent image data. | 03-05-2009 |
| 20090053145 | ANTI-VIRAL COMPOSITIONS AND METHODS OF USE IN CATTLE - Aspects of the present disclosure relate to therapeutic RNAi compositions and methods of use thereof for treating and/or preventing disease, disorder, and/or conditions—associated with bovine respiratory syncytial virus (BRSV) infections in cattle. | 02-26-2009 |
| 20090042247 | N-ACETYLGLUCOSAMINYLTRANSFERASE VB CODING SEQUENCES, RECOMBINANT CELLS AND METHODS - A previously unknown mammalian UDP-N-acetylglucosamine:α-6-D-mannoside β-1,6-N-acetylglucosaminyl-transferase (termed GlcNAc T-Vb herein) coding sequence, protein, recombinant host cells and antibodies which specifically bind GlcNAc T-Vb are described. In particular, GlcNAc T-Vb of mouse is disclosed. | 02-12-2009 |
| 20090041836 | Glycolipopeptide and uses thereof - A glycolipopeptide comprising a carbohydrate component, a peptide component and a lipid component, for use as a therapeutic or prophylactic vaccine. Also provided are monoclonal and polyclonal antibodies that recognize the glycolipopeptide of the invention, as well as uses thereof. | 02-12-2009 |
| 20090018075 | Peptides in Inhibiting Insects - The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a | 01-15-2009 |
| 20090018074 | Peptides for Inhibiting Insects - The subject invention pertains to the use of peptide fragments of cadherins (including cadherin-like proteins). The subject invention includes a cell (and use thereof) comprising a polynucleotide that expresses the peptide fragment. The subject invention includes methods of feeding the peptides to insects. In preferred embodiments, the peptides are fed to target insects together with one or more insecticidal proteins, preferably (but not limited to) B.t. Cry proteins. When used in this manner, the peptide fragment can not only enhance the apparent toxin activity of the Cry protein against the insect species that was the source of the receptor but also against other insect species. Preferably, the cadherin is a | 01-15-2009 |
| 20090004696 | Stabilized bioactive peptides and methods of identification, synthesis, and use - An intracellular selection system allows screening for peptide bioactivity and stability. Randomized recombinant peptides are screened for bioactivity in a tightly regulated expression system, preferably derived from the wild-type lac operon. Bioactive peptides thus identified are inherently protease- and peptidase-resistant. Also provided are bioactive peptides stabilized by a stabilizing group at the N-terminus, the C-terminus, or both. The stabilizing group can be a small stable protein, such as the Rop protein, glutathione sulfotransferase, thioredoxin, maltose binding protein, or glutathione reductase, an α-helical moiety, or one or more proline residues. | 01-01-2009 |
| 20080300985 | System and Method for Providing Media Content to Physically Proximate Mobile Devices - In one embodiment, a system and a method pertain to displaying an advertisement, determining media content related to the advertisement to send to a physically proximate mobile device, wirelessly connecting to the physically proximate mobile device, wirelessly transmitting the determined media content to the physically proximate mobile device using a short-range wireless communication protocol. | 12-04-2008 |
| 20080299895 | Systems and Methods for Providing Information to Exhibition Visitors - In one embodiment, a system and a method for providing information to exhibition visitors pertain to a visitor of an exhibition transmitting with a mobile device a code associated with the exhibition, a server computer receiving the code from the mobile device and identifying a link to downloadable content associated with the code, the server computer sending the link to the mobile device, the visitor selecting the link on the mobile device, and the mobile device downloading content relevant to the exhibition and displaying it to the user. | 12-04-2008 |
| 20080281919 | System and Method for Sharing Images - In one embodiment, a system and a method for sharing images relate to receiving images transmitted via the Internet and intended for viewing by a particular intended recipient, automatically storing the images in association with the intended recipient, detecting physical proximity of the intended recipient to a display device, and responsive to the detecting, displaying the images on the display device for the intended recipient. | 11-13-2008 |
| 20080268533 | Methods and Compositions Utilizing Myc and Gsk3Beta to Manipulate the Pluripotency of Embryonic Stem Cells - The present invention provides methods for stabilizing pluripotent cells through the transcriptional activation of c-myc. Alternatively, the cells are stabilized through the transcriptional activation of c-myc, and the stabilization of c-myc protein levels. c-myc protein can be stabilized through the inhibition of GSK3β or through other components of the cellular machinery that impact on c-myc stability. The invention contemplates the stabilized pluripotent cells produced using the methods described herein. Methods for the identification of compounds that modulate the stabilization of pluripotent cells through modulating transcriptional activation of c-myc, stabilization of c-myc protein levels, and/or inhibition of GSK3β activity are also contemplated. | 10-30-2008 |
