| UNIVERSITY OF FLORIDA RESEARCH FOUNDATION Patent applications |
| Patent application number | Title | Published |
|---|
| 20120100227 | KINASE PROTEIN BINDING INHIBITORS - The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating a variety of diseases and disorders, including cell proliferative disorders, especially cancer. | 04-26-2012 |
| 20120046246 | METHODS FOR TREATING OSTEOCLAST-RELATED DISEASE, COMPOUNDS AND COMPOSITIONS THEREOF - This invention relates to therapeutic methods for treating or preventing an osteoclast-related disease or disorder in a subject identified as in need of a treatment of bone diseases, compounds for such uses, and compositions thereof. | 02-23-2012 |
| 20120004284 | PDK INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF - The invention relates to methods of treating or preventing acquired or congenital mitochondrial diseases or disorders, including treating cell proliferation related disorders or diseases, such as cancer. The invention further relates to pharmaceutical compositions for treating such disorders or diseases. | 01-05-2012 |
| 20110294720 | APRATOXIN THERAPEUTIC AGENTS: MECHANISM AND METHODS OF TREATMENT - The instant invention describes macrocyclic compounds having therapeutic activity, and the mechanism and methods of treating disorders such as autoimmune diseases, inflammation, and cancer, tumors and cell proliferation related disorders. | 12-01-2011 |
| 20110230564 | ANT4 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF - The invention relates to methods for inducing male contraception and to methods of treating cell proliferation related disorders or diseases, such as cancer. The invention further relates to pharmaceutical compositions for inducing male contraception and for treating cell proliferation related disorders or diseases. | 09-22-2011 |
| 20110218143 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR - The invention generally provides compositions and methods for the repair or regeneration of a tissue or organ in need thereof. | 09-08-2011 |
| 20110195914 | MACROCYCLIC ANTIPROLIFERATION AGENTS AND METHODS OF TREATMENT - The instant invention describes macrocyclic compounds having antiproliferation activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders. | 08-11-2011 |
| 20110171221 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF A NEOPLASIA - Compositions and methods for the diagnosis, treatment and prevention of cancer, including prostate cancer and renal cell carcinoma, as well as for treatment selection. | 07-14-2011 |
| 20110123644 | MACROCYCLIC COMPOUNDS AND METHODS OF TREATMENT - The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, and HDAC mediated disorders. | 05-26-2011 |
| 20110110958 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEOPLASIA - The invention provides compositions and methods for the treatment of neoplasias that are cytotoxic to neoplastic cells or that modulate JAZ expression, subcellular localization, or biological activity. | 05-12-2011 |
| 20110092697 | METHODS OF PREPARATION OF MACROCYCLIC COMPOUNDS - The instant invention describes methods for producing macrocyclic compounds having antiproliferation activity, and useful in methods of treating disorders such as cancer, tumors and cell proliferation related disorders. | 04-21-2011 |
| 20110065664 | KINASE PROTEIN BINDING INHIBITORS - The invention relates to phosphorylation inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer. | 03-17-2011 |
| 20110023934 | SOLARTURF: SOLAR ENERGY HARVESTING ARTIFICIAL TURF - A SolarTurf unit has a plurality of solar blades, each blade comprising a donor-acceptor conjugated polymer (DA-CP) disposed between and electrically contacting a working electrode and a counter electrode where at least one of electrodes is transparent and where the plurality of solar blades have like or different DA-CPs having like color or different colors, for example, green. The SolarTurf unit includes an interconnect strip having a first electrically conductive surface and a second electrically conductive surface separated by an insulator. The working electrodes are electrically connected to the first electrically conductive surface and the counter electrodes are electrically connected to the second electrically conductive surface. The SolarTurf units can be combined into a device for harvesting light energy to provide an electric output. The SolarTurf device can have the appearance of a lawn or other plant, fungi, rock, sand or animal. | 02-03-2011 |
| 20100323444 | CULTURING AND DIFFERENTIATING NEURAL PRECURSOR CELLS - Systems and methods have been developed for large-scale propagation and differentiation of populations of neurons and glia from neural precursor cells derived from postnatal brain. Under culture conditions containing pituitary extract and mitogenic factors, cells derived from neural stem cells can be attached to a substrate, maintained and serially passaged in culture. Upon removal of mitogenic factors, clusters of neural progenitor cells can be induced that co-express markers of neural stem cells and immature neurons. Unlimited numbers of cells at characterized stages of neurogenesis can be produced. Upon maturation, neuronal cells extend processes and differentiate into mature neuronal phenotypes capable of generating action potentials. | 12-23-2010 |
| 20100298527 | GREEN TO TRANSMISSIVE SOLUBLE ELECTROCHROMIC POLYMERS - Green to transmissive soluble electrochromic polymers are conjugated polymers having a plurality of repeating units where repeating units are a plurality of substituted dioxyheterocycle based donor groups coupled to an acceptor group. The conjugated polymer absorbs radiation within a first band of the visible spectrum and a second band of the visible spectrum when in a neutral state resulting in a green color and is transmissive when in an oxidized state. The polymers are soluble allowing processing of films and coatings from solution. | 11-25-2010 |
| 20100190702 | Compositions and Methods of Treating Neoplasia - The invention features compositions and methods that are useful for the treatment of neoplasia by reducing base excision repair (BER). Such compositions are useful, for example, for enhancing the efficacy of known chemotherapeutics, such as DNA alkylating agents. In particular, the invention features agents that mimic the interaction of APC with pol-β. Such agents reduce the activity of long patch- and single nucleotide-base extension repair pathways. | 07-29-2010 |
| 20100176036 | ROTATING CONE CLASSIFIER - A classifier includes a central particle inlet, an inclined feed surface, and a classification surface. A plurality of particle feeding vanes are positioned above the feed surface, and the plurality of particle feeding vanes rotate above the feed surface. A plurality of classification vanes are positioned above the classification surface, and the plurality of classification vanes rotate above the classification surface. Particles enter the classifier through the inlet near an axis of rotation and flow radially outward on the feed surface to the classification surface. | 07-15-2010 |
| 20100137202 | COMPOSITIONS FOR REPROGRAMMING A CELL AND USES THEREFOR - The present invention generally provides therapeutic compositions and methods for treating a disease, disorder, or injury characterized by a deficiency in the number or biological activity of a cell of interest. The method provides compositions for generating reprogrammed cells or for increasing regeneration in a cell, tissue, or organ of interest. Such methods are useful for treating subjects having a deficiency in a particular cell type or in a polypeptide produced by that cell type. In particular, the invention provides prophylactic and therapeutic methods and compositions for ameliorating or preventing hyperglycemia associated with type I and type II diabetes and related complications. | 06-03-2010 |
| 20100003265 | Isolation, expansion and uses of tumor stem cells - Disclosed are methods for isolating cell populations enriched in tumor stem cells (cancer stem cells), and isolated cell populations substantially enriched in cancer stem cells that are tumorigenic in vivo. Also provided are new methods of tumor diagnosis and classification and personalized methods of treatment for subjects with tumors, based on the availability of populations of cancer stem cells derived from the subject's tumor using the disclosed methods. | 01-07-2010 |
| 20090239850 | Kinase protein binding inhibitors - The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating a variety of diseases and disorders, including cell proliferative disorders, especially cancer. | 09-24-2009 |
| 20090220136 | Image Guidance System for Deep Brain Stimulation - This invention provides computerized image guidance systems for deep brain stimulation (DBS) surgery and related methods that improve accuracy of positioning of electrodes in the brains of subjects. Image guidance systems in accordance with the present invention incorporate advanced features such as capability of displaying, in any desired plane of view, a digitized three-dimensional neuroanatomical brain map that can be form fitted to a patient's medical images, such as brain MR images, and capability of displaying on the patient's medical images both the contours of anatomic structures from a digitized brain map, and digitized electrode recording data obtained intra-operatively. | 09-03-2009 |
| 20080311596 | Genes of Porphyromonas Gingivalis W83 Involved in Invasion of Human Cells - Compositions and methods are provided for detection and treatment of | 12-18-2008 |
| 20080286361 | Gene Delivery - The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means. | 11-20-2008 |
| 20080251502 | CONTROLLED FUSION IN A FIELD REVERSED CONFIGURATION AND DIRECT ENERGY CONVERSION - A system and apparatus for controlled fusion in a field reversed configuration (FRC) magnetic topology and conversion of fusion product energies directly to electric power. Preferably, plasma ions are magnetically confined in the FRC while plasma electrons are electrostatically confined in a deep energy well, created by tuning an externally applied magnetic field. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions they are fused together by the nuclear force, thus forming fusion products that emerge in the form of an annular beam. Energy is removed from the fusion product ions as they spiral past electrodes of an inverse cyclotron converter. Advantageously, the fusion fuel plasmas that can be used with the present confinement and energy conversion system include advanced (aneutronic) fuels. | 10-16-2008 |
