| University of Florida Research Foundation Inc. Patent applications |
| Patent application number | Title | Published |
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| 20120133363 | MAGNETIC RESONANCE COMPATIBLE AND SUSCEPTIBILITY-MATCHED APPARATUS AND METHOD FOR MR IMAGING & SPECTROSCOPY - Electrodes, infusion cannula, and interventional MRI instrumentation, are constructed with multiple layers or mixtures of metals or alloys that allow the diamagnetic behavior of some metals to combine with the paramagnetic behavior of others, wherein the devices have a magnetic susceptibility which is close to that of the material, for example body tissue, being im The material may thereby be imaged using MRI with resultant images having greatly reduced distortion. Optimal metal composites are determined through mathematical modeling and measurements. In particular, MR compatible susceptibility-matched electrodes may be used for stimulation and for acquiring electroencephalography (EEG) data before, during and after MR image and spectroscopy measurements, with a significant reduction in distortion of the resulting images and spectra. In accordance with the invention, these electrodes may further be incorporated into micro-electrode arrays. In addition, MR compatible susceptibility-matched cannula can implanted before, during and after MR image and spectroscopy measurements, with a significant reduction in distortion of the resulting images and spectra. | 05-31-2012 |
| 20120129231 | ENGINEERING OF THERMOTOLERANT BACILLUS COAGULANS FOR PRODUCTION OF D(-)-LACTIC ACID - Genetically modified microorganisms having the ability to produce D(−)-lactic acid at temperatures between 30° C. and 55° C. are provided. In various embodiments, the microorganisms may have the chromosomal lactate dehydrogenase (ldh) gene and/or the chromosomal acetolactate synthase (alsS) gene inactivated. Exemplary microorganisms for use in the disclosed methods are | 05-24-2012 |
| 20120126204 | IR PHOTODETECTORS WITH HIGH DETECTIVITY AT LOW DRIVE VOLTAGE - An IR photodetector with high detectivity comprises an IR sensitizing layer situated between an electron blocking layer (EBL) and a hole blocking layer (HBL). The EBL and HBL significantly reduce the dark current, resulting in a high detectivity while allowing use of a low applied voltage to the IR photodetector. | 05-24-2012 |
| 20120123182 | DEVICES FOR THERMALLY INDUCED TRANSFORMATIONS CONTROLLED BY IRRADIATION OF FUNCTIONALIZED FULLERENES - An electromagnetic radiation activated device comprises a property changing material and at least one functionalized fullerene that upon irradiation of the functionalized fullerenes with electromagnetic radiation of one or more frequencies a thermally activated chemical or physical transformation occurs in the property changing material. The thermal activated transformation of the property changing material is triggered by the heating or combustion of the functionalized fullerenes upon their irradiation. The device can include a chemical agent that is embedded in the property changing material and is released when the material is heated by the functionalized fullerenes upon irradiation. | 05-17-2012 |
| 20120120643 | SOLAR-POWERED LIGHTING MODULE - A solar-powered lighting module is provided, including a solar cell for generating electricity when exposed to light, a battery for storing charge from the generated electricity, and a light generating device powered by the stored charge. In an embodiment, the module further includes a controller that regulates the current transmitted between the components of the module. In a further embodiment, the module is incorporated into an interface to an environmentally controlled space and can be positioned to light an interior portion of the space. In another embodiment, the solar cell and light generating device are transparent to allow light to pass through the interface. In a further embodiment, tinted-color conjugated polymers incorporated into the module limit the spectrum of light that can pass through the interface. In yet another embodiment, a method of modifying an existing interface with such a module is provided. | 05-17-2012 |
| 20120116186 | METHOD AND APPARATUS FOR EVALUATION OF A SUBJECT'S EMOTIONAL, PHYSIOLOGICAL AND/OR PHYSICAL STATE WITH THE SUBJECT'S PHYSIOLOGICAL AND/OR ACOUSTIC DATA - Embodiments of the subject invention relate to a method and apparatus for remote evaluation of a subject's emotive and/or physiological state. Embodiments can utilize a device that can be used to determine the emotional and/or physiological state of a subject through the measurement and analysis of vital signs and/or speech. A specific embodiment relates to a device capable of remotely acquiring a subject's physiological and/or acoustic data, and then correlating and analyzing the data to provide an assessment of a subject's emotional and/or physiological state. In a further specific embodiment, the device can acquire such data, correlate and analyze the data, and provide the assessment of the subject's emotional state and/or physiological in real time. | 05-10-2012 |
| 20120116174 | APPARATUSES AND METHODS FOR SUPPORTING AN UMBILICUS - In one embodiment, an umbilicus support apparatus includes a base and an armature that extends from the base, the armature including a flexible arm having a proximal end and a distal end, the armature further including a support head attached to the distal end of the arm, the support head including umbilicus securing means for securing an umbilicus. | 05-10-2012 |
| 20120115049 | SINGLE WALL CARBON NANOTUBE BASED AIR CATHODES - An embodiment of the invention is an air cathode having a porous membrane with at least one hydrophobic surface that contacts a conductive catalytic film that comprises single walled carbon nanotubes (SWNTs) where the nanotubes are in intimate electrical contact. The conductive film can include fullerenes, metals, metal alloys, metal oxides, or electroactive polymers in addition to the SWNTs. In other embodiments of the invention the air cathode is a component of a metal-air battery or a fuel cell. | 05-10-2012 |
| 20120114724 | ANTIMICROBIAL AGENT, METHOD OF PREPARING AN ANTIMICROBIAL AGENT AND ARTICLES COMPRISING THE SAME - The present disclosure is directed to method of preparing an antimicrobial agent comprising heating a dialdehyde polysaccharide. The method comprises subjecting a dialdehyde polysaccharide, such as a dialdehyde starch or a dialdehyde cellulose, to heating and/or sonication for a period of time. Also provided herein is an antimicrobial composition comprising the prepared dialdehyde polysaccharide. The antimicrobial composition is effective at killing microbial agents such as viruses and bacteria within a short period of time. | 05-10-2012 |
| 20120114655 | XYLAN UTILIZATION REGULON FOR EFFICIENT BIOPROCESSING OF HEMICELLULOSE AND USES THEREOF - The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from | 05-10-2012 |
| 20120108855 | INCREASED EXPRESSION OF TRANSHYDROGENASE GENES AND THEIR USE IN ETHANOL PRODUCTION - The invention provides isolated or recombinant ethanologenic bacteria that have increased expression of transhydrogenase genes and methods of preparation. The invention also provides methods of producing ethanol using the bacterium and corresponding kits. | 05-03-2012 |
| 20120108778 | CATHODICALLY COLORING YELLOW SOLUBLE ELECTROCHROMIC AND LIGHT EMITTING POLYMERS - Embodiments of the invention are directed to yellow-to-transmissive conjugated polymers, a method to prepare the yellow conjugated polymers, the use of the yellow conjugated polymers in an electrochromic and/or electroluminescent device comprising neutral state primary subtractive colored conjugated polymers, and a method to prepare the device comprising the yellow conjugated polymer. The yellow conjugated polymers comprise a sequence of dioxythiophene units alternating with aromatic units, thiophene units, furan units, and/or pyrrole units. The yellow conjugated polymers are prepared by cross-condensation reactions. The yellow conjugated polymers can be soluble and preparation of the device involves deposition of the yellow conjugated polymer from solution onto a surface. | 05-03-2012 |
| 20120108468 | Cell-based arrays, methods of making, and methods of using - Embodiments of the present disclosure provide for arrays, systems, and methods for the analyzing cells, methods of making arrays, and the like. | 05-03-2012 |
| 20120099103 | METHOD AND APPARATUS TO LASER ABLATION-LASER INDUCED BREAKDOWN SPECTROSCOPY - Embodiments of the invention relate to a method and apparatus for analyzing a target material. Specific embodiments can be referred to as laser ablation laser-induced breakdown spectroscopy (LA-LIBS). Embodiments of the invention relate to the use of a first laser beam pulse incident on a target material to create an ablation event so as to produce an ablation plume of target material. Such ablation events can include, for example, plasma ablation, sub-plasma ablation, and thermal desorption. At least a portion of the ablation plume of target material can then be transported a sufficient distance away from the ablation event that a second laser beam pulse can interact with the at least a portion of the ablation plume of target material to create an analytical plasma such that the analytical plasma is uncoupled from the ablation event. The creation of the analytical plasma results in one or more elements of the at least a portion of the ablation plume of target material undergoing atomic emission, which can, optionally, be collected and analyzed. | 04-26-2012 |
| 20120095065 | MACROCYCLIC COMPOUNDS AND METHODS OF TREATMENT - The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation. | 04-19-2012 |
| 20120094943 | ALPHA 7 NICOTINIC RECEPTOR SELECTIVE LIGANDS - The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration. | 04-19-2012 |
| 20120089396 | APPARATUS AND METHOD FOR SPEECH ANALYSIS - A system that incorporates teachings of the present disclosure may include, for example, an interface for receiving an utterance of speech and converting the utterance into a speech signal, such as digital representation including a waveform and/or spectrum; and a processor for dividing the speech signal into segments and detecting the emotional information from speech. The system is designed by comparing the speech segments to a baseline to identify the emotion or emotions from the suprasegmental information (i.e., paralinguistic information) in speech, wherein the baseline is determined from acoustic characteristics of a plurality of emotion categories. Other embodiments are disclosed. | 04-12-2012 |
| 20120087949 | OLIGONUCLEOTIDE MICELLES - The present invention provides homogenous populations of micelles, methods for preparing these populations, methods for treating or preventing a disease or disorder using the population of micelles of the invention. | 04-12-2012 |
| 20120083682 | ACOUSTIC SYSTEM FOR MONITORING THE PERFORMANCE OF LEFT VENTRICLE ASSIST DEVICES AND OTHER MECHANICAL DEVICES IMPLANTED IN A PATIENT'S BODY - Embodiments of the present invention are related to apparatus and methods for acoustically monitoring the performance of a medical device disposed within the body of a patient. According to one embodiment of an apparatus, the apparatus includes at least one acoustic sensor and a computer system that is connected to receive information from the acoustic sensor, wherein the acoustic sensor is adapted to receive a set of acoustic information that corresponds to acoustic activity within the body of said patient. The computer system is adapted for: (A) receiving the set of acoustic information, and (B) using the set of acoustic information to calculate location information relating to a location of a source of the acoustic activity. | 04-05-2012 |
| 20120078162 | METHOD AND DEVICE FOR ELECTROMOTIVE DELIVERY OF MACROMOLECULES INTO TISSUE - Electromotive delivery of macromolecules can be provided using a delivery device including a first chamber for contacting a macromolecule delivery medium to a surface of a tissue or other anatomy of a patient; and a second chamber for contacting a receiving medium to the patient. A first electrode can be disposed in the first chamber so as to not directly contact the macromolecule delivery medium. A second medium having a buffering agent can be used to keep the first electrode from coming into direct contact with the macromolecule delivery medium. A second electrode can be disposed within the receiving medium in the second chamber such that the second electrode does not directly contact the patient. An electric field can be generated using the first and second electrodes in order to cause the macromolecule delivery medium to move into the tissue of interest from the first chamber of the delivery device. | 03-29-2012 |
| 20120077241 | ETHANOLOGENIC BACTERIA AND THEIR USE IN ETHANOL PRODUCTION - The invention relates to bacterium that have increased resistance to furfural and methods of preparation. The invention also relates to methods of producing ethanol using the bacterium and corresponding kits. | 03-29-2012 |
| 20120070991 | CHEMICAL MECHANICAL POLISHING OF SILICON CARBIDE COMPRISING SURFACES - Slurry compositions and chemically activated CMP methods for polishing a substrate having a silicon carbide surface using such slurries. In such methods, the silicon carbide surface is contacted with a CMP slurry composition that comprises i) a liquid carrier and ii) a plurality of particles having at least a soft surface portion, wherein the soft surface portion includes a transition metal compound that provides a Mohs hardness ≦6, and optionally iii) an oxidizing agent. The oxidizing agent can include a transition metal. The slurry is moved relative to the silicon carbide comprising surface, wherein at least a portion of the silicon carbide surface is removed. | 03-22-2012 |
| 20120067395 | EARTH-TONED PHOTOVOLTAIC DEVICES - The invention is directed to an assembly of photovoltaic cells having at least two different earth-toned colors, where different colors are situated in different cells, the cells color being defined by the donor-acceptor (DA) π-conjugated polymer and an acceptor moiety combination comprising the photoactive layer of the cell, and where the different colored solar cells are coupled into an assembly. The assembly can be flexible and can have colors specifically arranged in a camouflage or other pattern. | 03-22-2012 |
| 20120061630 | GREEN SOLUBLE CONJUGATED POLYMERS WITH HIGH CHARGE CARRIER MOBILITIES - A donor-acceptor (DA) π-conjugated polymer with high charge transfer mobility has a plurality of D | 03-15-2012 |
| 20120059182 | Catalysts, Methods of Makting Catalysts, and Methods of Use - Embodiments of the present disclosure provide for acyclic diaminocarbenes (ADCs) catalysts such as those shown in FIG. | 03-08-2012 |
| 20120058530 | ENGINEERING THE PATHWAY FOR SUCCINATE PRODUCTION - This invention relates to the biocatalysts for the efficient production of succinic acid and/or other products from renewable biological feedstocks. The biocatalysts have a very high efficiency for the growth-coupled production of succinic acid and/or other products from carbohydrate feed stocks as a result of both genetic manipulations and metabolic evolution. More specifically, certain biocatalysts of the present invention produce succinic acid at high titers and yield in mineral salts media during simple pH-controlled, batch fermentation without the addition of any exogenous genetic material. The genetic manipulations of the present invention are concerned with the energy-conserving strategies coupled with the elimination of alternative routes for NADH oxidation other than the routes for succinic acid production. The biocatalysts contain glucose-repressed gluconeogenic phosphoenol pyruvate carboxykinase (pck) depressed by genetic modifications and a genetically-inactivated phosphotransferase system. In terms of succinic acid production efficiency, the biocatalysts of the present invention are functionally equivalent to succinate producing rumen bacteria such as | 03-08-2012 |
| 20120058488 | WIRELESS BASED MARINE PATHOGENS DETECTION SYSTEM - Embodiments of the present Invention provide antibody functionalized high electron mobility transistor (HEMT) devices for marine or freshwater pathogen sensing. In one embodiment, the marine pathogen can be | 03-08-2012 |
| 20120039919 | DIABETES DIAGNOSTIC, PROPHYLACTIC, AND THERAPEUTIC COMPOSITIONS AND METHODS - As described below, the present invention features compositions and methods featuring Pdx-1 polypeptides and fragments thereof for the diagnosis, prevention and treatment of diabetes. | 02-16-2012 |
| 20120032104 | PROCESSING METHOD FOR WATER SOLUBLE POLYMERIC MATERIALS - Embodiments of the invention are directed to a method of forming a film of an insoluble conjugated polymer (CP) by deposition of an ionic CP from aqueous solution and converting the ionic CP to the insoluble CP. The ionic CP can be the salt of a carboxylic acid, sulfonic acid, phosphonic acid, boronic acid, amine, imine, phosphine, thioether, or complexed bidentate or polydentate ligand. The insoluble CP film can be used with an aqueous electrolyte solution for use as: an electrochromic film; charge injection layer for a solar cell, LED, and FET; conventional paints; supercapacitor; battery; electronic paper; anti-static coating; transparent conductor; sensors; anti-microbial coating; adhesive; RFID; or memory system. | 02-09-2012 |
| 20120022363 | SYSTEM FOR DELIVERING CONFORMAL RADIATION THERAPY WHILE SIMULTANEOUSLY IMAGING SOFT TISSUE - A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system. | 01-26-2012 |
| 20120022199 | ANTI-AGING CHEMICALS FOR HIGH SOLIDS LOADING SLURRIES - Water structure breakers are included with dispersants in high solids aqueous slurries to stabilize the aqueous solution structure over a long period of time. The incorporation of a dispersant and a water structure breaker effectively inhibits the viscosity increase typically associated with high solid slurries, such as ground calcium carbonate (GCC) slurries, The inclusion of a small amount of water structure breaker inhibits change in the solution structure over that of a typical slurry lacking the water structure breaker, allowing longer storage and distribution periods for such slurries. | 01-26-2012 |
| 20120021517 | Bacterial Mediated Delivery of Nuclear Protein Into Pluripotent and Differentiated Cells - A modified | 01-26-2012 |
| 20120015045 | FUNCTIONALIZED FULLERENES AS ANTIFUNGAL AGENTS - Functionalized fullerenes are used in a method of combating fungal growth on surfaces and treating fungal diseases of patients. Surfaces that can be treated by the materials comprising an effective amount of functionalized fullerenes include those of fruits, vegetables, harvested grains, plants, or plant seeds. The method of combating fungal growth on a surface can be augmented but is not dependent on irradiation of the surface by light. Functional fullerenes are employed in various dosage forms such as topical, ingestible or administration. | 01-19-2012 |
| 20120009133 | POLY (NON-CONJUGATED DIENE) BASED SUNSCREENS - A poly(non-conjugated diene) based sunscreen has a plurality of repeating units where each repeating unit has at least one UV absorbing chromophore that is situated between and connected by chains to two mono-ene units where each UV absorbing chromophore absorb UVA and UVB light. The poly(non-conjugated diene) based sunscreen can be included with a vehicle for application to the skin to prevent sunburn. The poly(non-conjugated diene) based sunscreen can be prepared by acyclic diene metathesis polymerization. | 01-12-2012 |
| 20120008714 | MINIATURIZED ELECTRONIC DEVICE INGESTIBLE BY A SUBJECT OR IMPLANTABLE INSIDE A BODY OF THE SUBJECT - A miniaturized in-body electronic device is provided. One or more antennas (e.g., | 01-12-2012 |
| 20120003438 | GRAPHENE PROCESSING FOR DEVICE AND SENSOR APPLICATIONS - A supported graphene device comprises at least one graphene feature of 1 to about 10 graphene layers having a predetermined shape and pattern, with at least a portion of each graphene feature being supported on a substrate. In some embodiments the device comprises graphene features supported on crystalline semiconductor substrate, such as silicon or germanium. The graphene features on a crystalline semiconductor substrate can be fabricated by forming an amorphous carbon doped semiconductor on the crystalline semiconductor substrate and then epitaxially crystallizing the amorphous semiconductor with carbon migration to the surface to form a graphene feature of one or more graphene layers. The epitaxy can be promoted by heating the device or by irradiation with a laser. Methods for fabricating graphene on a variety of substrates, over large areas with controlled thicknesses employ ion implantation or other doping techniques followed by pulsed laser annealing or other annealing techniques that result in solid phase regrowth are presented. | 01-05-2012 |
| 20120000526 | AIR STABLE ORGANIC-INORGANIC NANOPARTICLES HYBRID SOLAR CELLS - A solar cell includes a low work function cathode, an active layer of an organic-inorganic nanoparticle composite, a ZnO nanoparticle layer situated between and physically contacting the cathode and active layers; and a transparent high work function anode that is a bilayer electrode. The inclusion of the ZnO nanoparticle layer results in a solar cell displaying a conversion efficiency increase and reduces the device degradation rate. Embodiments of the invention are directed to novel ZnO nanoparticles that are advantageous for use as the ZnO nanoparticle layers of the novel solar cells and a method to prepare the ZnO nanoparticles. | 01-05-2012 |
| 20110314924 | STRUCTURE AND FABRICATION OF A MICROSCALE FLOW-RATE/SKIN FRICTION SENSOR - A floating element shear sensor and method for fabricating the same are provided. According to an embodiment, a microelectromechanical systems (MEMS)-based capacitive floating element shear stress sensor is provided that can achieve time-resolved turbulence measurement. In one embodiment, a differential capacitive transduction scheme is used for shear stress measurement. The floating element structure for the differential capacitive transduction scheme incorporates inter digitated comb fingers forming differential capacitors, which provide electrical output proportional to the floating element deflection. | 12-29-2011 |
| 20110313174 | TRIANIONIC PINCER LIGANDS, A CR(III)/CR(V) CATALYTIC SYSTEM AND ITS USE FOR CATALYTIC AEROBIC OXIDATION OF ORGANIC SUBSTRATES - An embodiment of the invention is a novel Cr(V) OCO | 12-22-2011 |
| 20110311769 | ANTIFOULING SURFACES, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is an article comprising a substrate; a polymer disposed upon the substrate; the polymer having a number average molecular weight of about 2,000 to about 5,000 grams per mole; where each polymer is separated from a neighboring polymer by an average distance of 2.5 Angstroms to 5,000 Angstroms. Disclosed herein is a method comprising disposing upon a substrate a polymer; the polymer having a number average molecular weight of 2,000 to about 5,000 grams per mole. | 12-22-2011 |
| 20110311586 | Materials and methods for respiratory disease control in canines - The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention. | 12-22-2011 |
| 20110311067 | DIGITAL SOUND LEVELING DEVICE AND METHOD TO REDUCE THE RISK OF NOISE INDUCED HEARING LOSS - Devices and methods for digital sound leveling are disclosed. The subject devices and methods can be used to reduce the risk of noise induced hearing loss. According to an embodiment, an audio file can be parsed into frames that are filtered using an A-weighted digital filter and scaled to a desired power level. Accordingly, the dynamic range of an audio output at a particular volume level can be controlled. | 12-22-2011 |
| 20110301159 | KINASE INHIBITOR COMPOUNDS - The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof. | 12-08-2011 |
| 20110300347 | Fabrication of Patterned Nanofibers - Various methods and systems are provided for the fabrication of patterned nanofibers. In one embodiment, a method includes generating a layer of electrospun nanofibers from a polymer solution and patterning the layer of electrospun nanofibers using ultraviolet (UV) lithography. The patterned electrospun nanofibers may then be thermally treated to form patterned carbon nanofibers. In another embodiment, a device includes a layer of patterned carbon nanofibers formed by generating electrospun nanofibers from a polymer solution, patterning the electrospun nanofibers using UV lithography, and converting the patterned electrospun nanofibers into patterned carbon nanofibers using a thermal treatment. In another embodiment, a method includes depositing electrospun nanofibers for a first predefined period of time, dissipating charge on the deposited electrospun nanofibers for a second predefined period of time where no electrospun nanofibers are deposited, and sequentially repeating the depositing and dissipating steps to from a layer of electrospun nanofibers having a predefined thickness. | 12-08-2011 |
| 20110293470 | CONJUGATED POLYELECTROLYTE CAPSULES: LIGHT ACTIVATED ANTIMICROBIALS - Hollow conjugated polyelectrolyte (HCPE) microcapsules contain at least one conjugated polyelectrolyte and at least one other polyelectrolyte of complementary charge and the microcapsule has a hollow core. The conjugated polyelectrolyte is a polymer with a multiplicity of charged repeating units where a portion of the charged repeating units form a pi-conjugated sequence. The complementary polyelectrolyte is a polymer with a complementary charged repeating unit to the charged repeating units of the conjugated polyelectrolyte. The HCPE microcapsules can be formed by successively coating a sacrificial core with alternating layers of complementary polyelectrolytes, at least one of which is a conjugated polyelectrolyte. The sacrificial core can be removed to form the hollow center of a HCPE microcapsule. The HCPE microcapsules can be contacted with a medium containing microbes where the HCPE microcapsules associate with the microbes and efficiently kill the microbes when irradiated with light or other electromagnetic radiation. | 12-01-2011 |
| 20110292490 | METHOD AND APPARATUS FOR PROVIDING HIGH-FILL-FACTOR MICROMIRROR/MICROMIRROR ARRAYS WITH SURFACE MOUNTING CAPABILITY - Embodiments of the subject invention relate to micromirror devices and methods of fabricating a micromirror/micromirror array. According to an embodiment, micromirrors can be fabricated from a semiconductor substrate where after forming actuators and bonding pads on a front side of the semiconductor substrate, the device is flipped over to have a portion of the back side of the substrate removed and formed to become the mirror plate surface. The subject micromirrors can allow further miniaturization of endoscopes and other optical applications without sacrificing the optical aperture through their surface mounting capabilities. | 12-01-2011 |
| 20110289295 | SYSTEM, METHOD, AND MEDIA FOR NETWORK TRAFFIC MEASUREMENT ON HIGH-SPEED ROUTERS - A data structure is provided for storing network contact information based on an array of physical memory locations. Virtual vectors are constructed for each source, wherein each element in each virtual vector is assigned to a corresponding physical memory location within the array. The physical memory locations are shared between the virtual vectors uniformly at random so that the noise introduced by sharing can be predicted and removed. A method for storing network contact information is also provided in which a hash function is performed using the address of a source host to find a virtual vector for holding information about the source host. A second hash function is performed using the address of a destination host to find a virtual memory location, within the virtual vector, for holding information about the destination host. Finally, information is stored at a physical memory location assigned to the virtual memory location. Estimation range enhancement is further provided by performing multiple estimations with different sampling probabilities and selecting a best estimation based on a maximum likelihood method. | 11-24-2011 |
| 20110288253 | MULTI-COLORED CONJUGATED POLYMERS WITH HIGHLY TRANSMISSIVE OXIDIZED STATE - Embodiments of the invention are directed to random conjugated copolymers comprising a plurality of one or more different donor (D) repeating units and a plurality of at least one acceptor (A) repeating unit. At least one of the D units has a solubilizing substituent, statistically a portion of the A repeating units are separated from each other by only one D units and a plurality of the A unit are adjacent to one the D units having the solubilizing substituents. The random conjugated copolymers are black or colored in the neutral state and highly transmissive in the oxidized state. The random conjugated copolymers have the structure -[(D) | 11-24-2011 |
| 20110287074 | Antimicrobial Compositions, Methods of Manufacture Thereof and Articles Comprising the Same - Disclosed herein are a variety of applications for an antimicrobial agent. The antimicrobial agent comprises a silanol containing molecule, the silanol containing molecule comprising silanols (R | 11-24-2011 |
| 20110281310 | MATERIALS AND METHODS FOR THE EFFICIENT PRODUCTION OF ACETATE AND OTHER PRODUCTS - The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid. | 11-17-2011 |
| 20110276179 | IMAGING PLATFORM TO PROVIDE INTEGRATED NAVIGATION CAPABILITIES FOR SURGICAL GUIDANCE - An imaging platform system that provides integrated navigation capabilities for surgical guidance. The system can include two robotic arm systems, one robotic arm system holding an imaging source, and the other holding an imaging sensor. These robotic arm systems are able to move and provide three-dimensional tomographic scans, static radiographic images, and dynamic fluoroscopic image sequences. A third robotic arm system can be included in the imaging platform system as a surgeon guided tool-holder to accurately implement an image-guided surgical plan. The robotic systems can manipulate imaging and surgical components into and out of the operative field as needed, enhancing the choreography between a surgical team and assistive technology. A handle can be included as part of a manual positioning control subsystem. The handle can be mounted to an imaging robotic system above and/or below an operating table, and also can be mounted to a tool-holding robotic system. | 11-10-2011 |
| 20110275581 | NUCLEAR EXPORT INHIBITORS OF TOPOISOMERASE II ALPHA - A method of treating cancer in a subject comprising the step of administering to the subject in need thereof an effective amount of a combination of a compound that binds a nuclear export signal (NES inhibitor) on topoisomerase IIα and a topoisomerase inhibitor. Twenty small molecule inhibitors (SMI) that bind to the two nuclear export sequences (NES) topo IIα have been identified from the NCI database using computer-generated molecular modeling. These SMI will improve the effectiveness of topo II directed therapeutics, particularly in the treatment of diseases such as multiple myeloma (MM). In vitro apoptosis assays indicate that these drugs may be effective as single agents or in combination with currently used cancer drugs that target topo II. | 11-10-2011 |
| 20110263468 | In-Situ Lubrication of Sliding Electrical Contacts - Embodiments of the present disclosure include electrically conductive solid lubricant transfer films, methods of making the same, and the like. | 10-27-2011 |
| 20110262342 | ON-DEMAND PORTABLE CHLORINE DIOXIDE GENERATOR - An on-demand portable chlorine dioxide generator has a reagent bound medium in a first enclosed volume; a complementary reagent solution in a second enclosed volume, and a structure for selecting between a first position where the complementary reagent solution is forced through the reagent bound medium and a second position where said complementary reagent solution remains isolated from the reagent bound ion exchange medium, where a ClO | 10-27-2011 |
| 20110262340 | PRODUCTION OF CARBON NANOSTRUCTURES FROM FUNCTIONALIZED FULLERENES - Electromagnetic irradiation of functionalized fullerenes in an oxygen-free environment induces conversion of the functionalized fullerenes to carbon nanotubes, carbon nanohorns, carbon onions, diamonds and/or carbon schwarzites. The carbon nanotubes can be multi-wall carbon nanotubes. Advantageously, the subject invention can be used for in-situ synthesis of carbon nanostructures within a matrix to form a carbon nanostructure composite, where positioning of the carbon nanostructures is controlled by the manner of dispersion of the functionalized fullerenes in the matrix. Carbon nanotube comprising features, such as electrical connects, can be formed on a surface by irradiating a portion of a functionalized fullerene coating with a laser beam. | 10-27-2011 |
| 20110256802 | CYCLIC SELF-LIMITING CMP REMOVAL AND ASSOCIATED PROCESSING TOOL - A cyclic method of chemical mechanical polishing (CMP) a wafer having a surface includes placing the wafer on a platen in a CMP apparatus and then performing a multi-step CMP comprising process. The multi-step CMP process includes delivering a first chemical composition onto the wafer while on the platen for a first time duration, and without removing the wafer from the platen, delivering a second chemical composition different from the first composition onto the wafer for a second time duration after the first time duration. The multi-step CMP comprising process includes CMP removal using a slurry during one of the first and second time durations and a non-polishing process during the other of the first and second time durations. The multi-step CMP comprising process is repeated a plurality of times. | 10-20-2011 |
| 20110244493 | CELL-BASED DETECTION OF APF THROUGH ITS INTERACTION WITH CKAP4 FOR DIAGNOSIS OF INTERSTITIAL CYSTITIS - An assay system designed to detect a protein biomarker in urine that is diagnostic for interstitial cystitis (IC). The presence of a 9 amino acid glycopeptide, antiproliferative factor (APF), in urine is unique to patients with IC. Urine samples from patients who exhibit symptoms consistent with IC are added to the assay system. Binding of APF to the cytoskeletal associated protein 4 (CKAP4) is positive for the presence of APF in urine and diagnostic for IC. The diagnostic system is a significant and surprising advance in diagnosis of IC and has commercial applications relevant to women and men who suffer from symptoms consistent with IC. | 10-06-2011 |
| 20110237772 | POLYESTERACETALS - A polyesteracetal contains —[C(O)(CR | 09-29-2011 |
| 20110233932 | METHOD AND APPARATUS FOR PROVIDING AN ELECTRICAL ENERGY SYSTEM - Embodiments of the subject invention relate to a method and apparatus for providing an electrical energy system. A specific embodiment can incorporate at least one energy harvesting module (H-module), at least one energy storage module (S-module), and at least one power electronic circuit module (C-module). The various modules can be integrated into a standard battery configuration. Specific embodiments pertain to a reconfigurable energy system with modules that can be disconnected and reconnected into different shapes and configurations. | 09-29-2011 |
| 20110222337 | FLOATING-BODY/GATE DRAM CELL - Memory cell structures and biasing schemes are provided. Certain embodiments pertain to a modified floating-body gate cell, which can provide improved retention times. In one embodiment, a gated diode is used to drive the gate of a second transistor structure of a cell. In another embodiment, a body-tied-source (BTS) field effect transistor is used to drive the gate of the second transistor structure of a cell. | 09-15-2011 |
| 20110221039 | DEFECT CAPPING FOR REDUCED DEFECT DENSITY EPITAXIAL ARTICLES - An epitaxial article includes a substrate having a substrate surface having a substrate surface composition including crystalline defect or amorphous regions and crystalline non-defect regions. The crystalline defect or amorphous regions are recessed from the substrate surface by surface recess regions. A capping material fills the surface recess regions to provide capped defects that extend from a top of the defect regions to the substrate surface. The capping material is compositionally different from the substrate surface composition. An epitaxial layer over the substrate surface provides an average crystalline defect density in at least one area having a size ≧0.5 μm | 09-15-2011 |
| 20110215590 | Dual-Mode Piezoelectric/Magnetic Vibrational Energy Harvester - Embodiments of a vibrational energy harvester are provided. A vibrational energy harvester can include a translator layer sandwiched between two stator layers. The translator layer can include a plate having an array of magnets and two or more piezoelectric patches coupled to a tether beam attached to the plate. The stator layers can have a printed circuit board with multilayer electrical windings situated in a housing. In operation, vibration of the housing can result in bending of the piezoelectric patches coupled to the tether beam. This bending simultaneously results in a relative displacement of the translator, which causes a voltage potential in the piezoelectric patches, and a relative velocity between the translator and the stators, which induces a voltage potential in the stator coils. These voltage potentials generate an AC power, which can be converted to DC power through a rectification circuit incorporating passive and active conversion. | 09-08-2011 |
| 20110206831 | TRANSPARENT INORGANIC-ORGANIC HYBRID MATERIALS VIA AQUEOUS SOL-GEL PROCESSING - A sol to form an inorganic-organic hybrid coating having a thick highly transparent hard coating is described. The hybrid coating is formed from a combined aqueous sol with least one hydrolyzable silane and at least one hydrolyzable metal oxide precursor where the only organic solvents present are those liberated upon hydrolysis of the silanes and metal oxide precursors. In one embodiment an inorganic-organic hybrid coating is formed by combination of a sol, prepared by the hydrolysis of tetraethoxysilane and γ-glycidoxypropyltrimethoxysilane with an excess of water, and a sol, prepared by the hydrolysis of titanium tetrabutoxide and γ-glycidoxypropyltrimethoxysilane with a deficiency of water. A plastic substrate can be coated with the combined sol and the combined sol gelled to a thickness of at least 5 μm with heating to less than 150° C. | 08-25-2011 |
| 20110206688 | Enhancing Vessel Lesion Homing and Repair Potential of Stem Cells - Disclosed herein are methods of enhancing repair of vascular lesions involving the administration of cells in which TGF-β expression and/or activity has been transiently blocked. Other methods involve the administration of a TGF-β blocking agent to a subject who has a vascular lesion or is at risk of developing a vascular lesion. Alternatively, a TGF-β blocking agent and treated cells are co-administered to a subject in need thereof. | 08-25-2011 |
| 20110200910 | ADVANCED MATERIALS AND DESIGN FOR LOW TEMPERATURE SOFCS - Embodiments of the invention are directed to SOFC with a multilayer structure comprising a porous ceramic cathode, optionally a cathodic triple phase boundary layer, a bilayer electrolyte comprising a cerium oxide comprising layer and a bismuth oxide comprising layer, an anion functional layer, and a porous ceramic anode with electrical interconnects, wherein the SOFC displays a very high power density at temperatures below 700° C. with hydrogen or hydrocarbon fuels. The low temperature conversion of chemical energy to electrical energy allows the fabrication of the fuel cells using stainless steel or other metal alloys rather than ceramic conductive oxides as the interconnects. | 08-18-2011 |
| 20110200172 | METHOD AND APPARATUS FOR COMPUTED IMAGING BACKSCATTER RADIOGRAPHY - Systems and methods of x-ray backscatter radiography are provided. A single-sided, non-destructive imaging technique utilizing x-ray radiation to image subsurface features is disclosed, capable of scanning a region using a fan beam aperture and gathering data using rotational motion. | 08-18-2011 |
| 20110195464 | BIOCATALYSTS AND METHODS FOR CONVERSION OF HEMICELLULOSE HYDROLYSATES TO BIOBASED PRODUCTS - The invention relates to processes and biocatalysts for producing ethanol and other useful products from biomass and/or other materials. Initial processing of lignocellulosic biomass frequently yields methylglucuronoxylose (MeGAX) and related products which are resistant to further processing by common biocatalysts. Strains of | 08-11-2011 |
| 20110194117 | MIRROR-TILT-INSENSITIVE FOURIER TRANSFORM SPECTROMETER - Methods and designs for providing reduced sensitivity to mirror tilt in Fourier transform spectrometers are disclosed. According to an embodiment for two-directional tilt compensation, the FT spectrometer can include a beam splitter positioned to receive an incoming beam from a light source and split the incoming beam into a first sub-beam and a second sub-beam, a corner-cube retroreflector positioned to receive the first sub-beam from the beam splitter, a dual reflective mirror positioned to receive the first sub-beam from the corner-cube retroreflector at one surface and the second sub-beam at the other surface. An optical path delay can be created using a set of mirrors, tilting the beam splitter and/or a glass cube. | 08-11-2011 |
| 20110191909 | MATERIALS AND METHODS FOR MODULATING SEED SIZE, SEED NUMBER, AND SEED SUGAR CONTENT IN PLANTS - The subject invention concerns materials and methods for modulating seed size in plants. In one embodiment, seed size is decreased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed size is increased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. The subject invention also concerns materials and methods for modulating seed number or sugar content in plants. In one embodiment, seed number or sugar content is increased relative to wild type seed by inhibiting or knocking out expression of a sorbitol dehydrogenase (Sdh) gene or the gene product thereof. In another embodiment, seed number or sugar content is decreased relative to wild type seed by increasing expression of an Sdh gene or the gene product thereof. | 08-04-2011 |
| 20110187207 | METHOD AND APPARATUS FOR MOTIONAL/VIBRATIONAL ENERGY HARVESTING VIA ELECTROMAGNETIC INDUCTION - A method and apparatus for motional/vibrational energy harvesting are disclosed. Embodiments of the subject invention utilize the non-resonant chaotic behavior of a free-rolling magnet to generate power. In one embodiment, the magnet can be spherical, cylindrical, or elliptical. The magnet can roll about a linear, cylindrical, helical, or cage-like track. The changing magnetic flux due to the magnet rolling about the track induces current in surrounding coils. The coils can be provided around the track using a continuous winding placement, segmented winding placement, or fractional winding placement. Multiple coil phases are also possible. For embodiments utilizing multiple magnets, spacers can be used to maintain a separation between magnets. | 08-04-2011 |
| 20110179640 | ENHANCED MAGNETIC SELF-ASSEMBLY USING INTEGRATED MICROMAGNETS - Embodiments of the invention relate to a method and system for magnetic self-assembly (MSA) of one or more parts to another part. Assembly occurs when the parts having magnet patterns bond to one another. Such bonding can result in energy minima The magnetic forces and torques—controlled by the size, shape, material, and magnetization direction of the magnetic patterns cause the components to rotate and align. Specific embodiments of MSA can offer self-assembly features such as angular orientation, where assembly is restricted to one physical orientation; inter-part bonding allowing assembly of free-floating components to one another; assembly of free-floating components to a substrate; and bonding specificity, where assembly is restricted to one type of component when multiple components may be present. | 07-28-2011 |
| 20110177974 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 07-21-2011 |
| 20110177108 | LIPID COMPOUNDS FOR SUPRESSION OF TUMORIGENESIS - The present invention provides compounds, or pharmaceutically acceptable salts or analogs thereof, which exhibit anti-tumor activity. The present invention also includes methods for inhibiting the growth of cancer cells by contacting an effective amount of a compound of the present invention with the cancer cells in vitro or in vivo. | 07-21-2011 |
| 20110171650 | GENE EXPRESSION RELATED TO PREECLAMPSIA - Gene expression patterns contemporaneous with early placental development in the first trimester of preeclamptic versus unaffected pregnancies have been obtained. Observation of differences in these gene expression patterns has allowed the identification of biomarkers that are useful in predicting and monitoring preeclampsia. These biomarkers are also useful in screening potential therapeutics for efficacy in the prevention or treatment of preeclampsia. | 07-14-2011 |
| 20110168540 | DESALINATION APPARATUS AND PROCESS - Disclosed herein are an apparatus and a process that can be used to remove sulfur dioxide other environmentally hazardous contaminants from a gaseous waste stream while at the same time providing a source of purified water. The process can be used for the desalination of sea or brackish water, or for the concentration of contaminated waste water. The method comprises feeding a gaseous waste stream that comprises sulfur dioxide into a diffusion tower. Feed water is sprayed onto a packing material in the diffusion tower to form a thin film of feed water on a surface of the packing material. Sulfur dioxide diffuses into the thin film of feed water to form water that contains sulfur dioxide. The gaseous waste stream is simultaneously humidified. The humidified gaseous waste stream is then subjected to direct contact condensation to obtain purified water. | 07-14-2011 |
| 20110166107 | METHODS AND KITS FOR DETECTING RISK FACTORS FOR DEVELOPMENT OF JAW OSTEONECROSIS AND METHODS OF TREATMENT THEREOF - Methods of and kits for determining the pharmacogenetic, pharmacokinetic and cellular basis of bisphosphonate-induced osteonecrosis of the jaw (BONJ) involve associating particular proteins and particular single nucleotide polymorphisms with a risk for developing BONJ after receiving bisphosphonate treatment. Methods and kits for identifying the genetic basis for a patient's predisposition to BONJ, and methods of identifying patients who are prone to develop BONJ following bisphosphonate administration provide for the development of a tool for physicians to prescribe treatment protocols for BONJ patients based on the patients' genomes (“personal/tailored medicine”). | 07-07-2011 |
| 20110164302 | METHOD AND APPARATUS FOR MODULATING LIGHT - Embodiments relate to a method and apparatus for producing polarized light, having a modulator crystal, where the modulator crystal incorporates a birefringent electro-optic material. The modulator crystal has an optic axis, a first polarization axis, and a second polarization axis, where the first polarization axis and second polarization axis are each perpendicular to the optic axis and perpendicular to each other. The apparatus can also include an electrode pair, where application of an electric field modulates light passing through the modulator crystal that is polarized along the first polarization axis. Embodiments pertain to a method and apparatus for modulating light. The apparatus incorporates a modulator crystal having a electro-optic material. The device also has at least two electrode pairs, where each electrode pair that modulates light passing through the modulator crystal that has a direction of travel that has a component parallel to the optic axis. | 07-07-2011 |
| 20110159605 | Surface Grafted Conjugated Polymers - A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides. | 06-30-2011 |
| 20110155840 | MORPHING AIRCRAFT - A morphing aircraft that is achieves multi-modality location and camouflage for payload emplacement The morphing aircraft includes a substantially cylindrical fuselage including a shape configured as a packaging container with a first end and a second end A set of wings is coupled to the fuselage The set of wings includes a first position where the set of wings is extended outwards from the fuselage and a second position where the set of wings is retracted inwards towards the fuselage A tail is coupled to the second end of the cylindrical fuselage The tail includes a first position where the tail is extended outward from the fuselage and a second position where the tail is retracted inward towards the fuselage A propeller is mounted to the first end of the fuselage An engine is mechanically coupled to the propeller The engine is enclosed within the fuselage and powers the propeller. | 06-30-2011 |
| 20110155202 | Miniature Thermoelectric Power Generator - The subject invention pertains to thermoelectric power generation. According to certain embodiments, a stack of silicon-micromachined chips can be connected to form a cylindrical heat exchanger that enables a large, uniform temperature difference across a radially-oriented thermopile. Each layer in the stack can comprise two thermally-isolated concentric silicon rings connected by a polyimide membrane that supports patterned thermoelectric thin films. The polyimide membrane can be formed by selectively etching away the supporting silicon, resulting in thermally-isolated inner and outer rings. In operation, hot gas can flow through a finned central channel, and an external cross flow can enhance heat transfer to ambient to keep the outer surfaces cool. The resulting temperature gradient across the thermopile generates a voltage potential across the open ends due to the Seebeck effect. When connected to a load, current flows, and electrical power is supplied by the generated voltage potential caused by the temperature gradient. | 06-30-2011 |
| 20110154375 | MODULAR PLATFORM ENABLING HETEROGENEOUS DEVICES, SENSORS AND ACTUATORS TO INTEGRATE AUTOMATICALLY INTO HETEROGENOUS NETWORKS - A system includes a hardware platform, at least one driver, a plurality of devices connected to the hardware platform, a middleware interface, and a plurality of software services. Each of the plurality of devices is selected from the group consisting of sensors and actuators. The plurality of software services is generated by the at least one driver, wherein a software service associates with a device, and wherein each of the software services complies with the middleware interface. A method for interfacing a plurality of devices to a hardware platform includes communicably connecting each of the plurality of devices to the hardware platform, converting each of the plurality of devices into a programmable software service using a driver, and programming each of the software services to comply with a middleware interface. | 06-23-2011 |
| 20110152206 | THERAPEUTIC COMBINATIONS FOR USE IN NEOPLASIA - The invention features compositions and methods that are useful for the treatment of neoplasia (e.g., breast cancer) by increasing DNA damage and reducing base excision repair (BER). | 06-23-2011 |
| 20110151077 | METHOD OF INHIBITION OF ENZYMATIC BROWNING IN FOOD USING HYPOTAURINE AND EQUIVALENTS - A method of inhibiting enzymatic browning in food involves the contacting of hypotaurine, a salt of hypotaurine or an equivalent of hypotaurine with the food. The hypotaurine can be provided from solution, an extract, or in solid form to a food that can loose its appeal to a consumer due to browning, such as cut fruits and vegetables, seafood, or a beverage. The antibrowning agent can be applied to the food by spraying, dusting, dipping, or dissolving, depending upon the form of the food to which the agent is added. | 06-23-2011 |
| 20110150938 | Supercrystalline Colloidal Particles and Method of Production - The present invention concerns size- and shape-controlled, colloidal superparticles (SPs) and methods for synthesizing the same. Ligand-functionalized nanoparticles such as nonpolar-solvent-dispersible nanoparticles, are used, and the solvophobic interactions can be controlled. Advantageously, supercrystalline SPs having a superlattice structure, such as a face-centered cubic structure, can be produced. Further, the methods of the invention can provide SPs that self-assemble and are monodisperse. The SPs can be doped with organic dyes and further assembled into more complex structures. | 06-23-2011 |
| 20110140458 | METHOD AND APPARATUS FOR MOTIONAL/VIBRATIONAL ENERGY HARVESTING VIA ELECTROMAGNETIC INDUCTION USING A MAGNET ARRAY - Embodiments of the subject invention pertain to a method and apparatus for vibrational energy harvesting via electromagnetic induction using a magnet array. Specific embodiments of the subject invention incorporate at least one conductive coil and at least one magnet array. Magnets used in such magnet arrays can be permanent magnets of various shapes, such as arc-shaped, square, rectangular, wedge, or trapezoidal. These magnet arrays can then be, for example, circular, hexagonal, rectangular, or square in external shape and create various types of internal magnetic fields, such as dipole, quadrupole, hexapole, or octapole magnetic fields. Through use of a magnet array, embodiments of the invention can increase the strength of magnetic fields by approximately 10 times compared to typical vibrational energy harvesters. The 10 time increase in the strength of the magnetic fields can result in up to a 100-fold increase in power. Preferably, the magnetic fields created by the subject device are substantially, if not completely, enclosed within the device. | 06-16-2011 |
| 20110139990 | MEMS-BASED FTIR SPECTROMETER - A MEMS-based Fourier Transform (FT) spectrometer is provided. According to an embodiment, the MEMS-based FT spectrometer is an FT infrared (FTIR) spectrometer. The FT spectrometer can include a beam splitter positioned to receive an incoming beam from a light source and split the incoming beam into a first sub-beam and a second sub-beam, a fixed mirror positioned to receive the first sub-beam from the beam splitter, a scanning MEMS mirror positioned to receive the second sub-beam from the beam splitter, and a photodetector, wherein a reflected first sub-beam from the fixed mirror and a reflected second sub-beam from the scanning MEMS mirror recombine at the beam splitter and become directed to the photodetector. According to one embodiment, the photodetector is a MEMS-based IR detector. In addition, the MEMS-based IR detector can be an un-cooled IR detector having a capacitive sensing structure. | 06-16-2011 |
| 20110137328 | Nerve Repair with a Hydrogel and Optional Adhesive - The subject invention provides materials and methods for effective nerve repair. In a preferred embodiment, the subject invention provides nerve repair methods comprising the use of a fibrin glue and a polyethylene glycol (PEG) hydrogel to coapt severed nerve stumps or nerve grafts. | 06-09-2011 |
| 20110137179 | DIFFERENTIAL LASER-INDUCED PERTURBATION (DLIP) FOR BIOIMAGING AND CHEMICAL SENSING - Methods for imaging or optical sensing of a material are provided. A first fluorescent image or optical signal of a material can be recorded, the material can be perturbed, and then a second fluorescent image or optical signal of the material can be recorded. The two fluorescent images or signals can be subtracted to give a differential image or optical signal. | 06-09-2011 |
| 20110124569 | MACROCYCLIC COMPOUNDS, PROTEASE INHIBITION, AND METHODS OF TREATMENT - The instant invention describes macrocyclic depsipeptide lyngbyastatins, and methods of treating disorders such as COPD, emphysema, rheumatoid arthritis, and aging related disorders. | 05-26-2011 |
| 20110121659 | METHOD AND APPARATUS FOR HIGH EFFICIENCY AC/DC CONVERSION OF LOW VOLTAGE INPUT - Embodiments of the subject invention relate to a method and apparatus for providing a low-power AC/DC converter designed to operate with very low input voltage amplitudes. Specific embodiments can operate with input voltages less than or equal to 1 V, less than or equal to 200 mV, and as low as 20 mV, respectively. Embodiments of the subject low-power AC/DC converter can be utilized in magnetic induction energy harvester systems. With reference to a specific embodiment, a maximum efficiency of 92% was achieved for a 1 V input, and efficiencies exceeding 70% were achieved for a 200 mV input. A specific embodiment functioned properly when connected to a magnetic energy harvester device operating below 200 mV input. | 05-26-2011 |
| 20110118323 | MACROCYCLIC COMPOUNDS AND METHODS OF TREATMENT - The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation. | 05-19-2011 |
| 20110116967 | SELF-STERILIZING DEVICE USING PLASMA FIELDS - Embodiments of the invention relate to a method and apparatus for self-sterilizing a surface or other portion of the apparatus and/or sterilizing other objects. Embodiments can utilize self-generated and/or remotely controlled plasma fields for the purpose of self-sterilization and/or sterilization of another object. Embodiments of the invention can have broad applications in procedures and equipment requiring the sterility of devices used for medical procedures, decontamination procedures, drug delivery, sterility of consumer products, and sterility of food preparation equipment and tools. | 05-19-2011 |
| 20110110490 | METHOD AND APPARATUS FOR X-RAY RADIOGRAPHIC IMAGING - Embodiments of the invention relate to a method for x-ray radiography and apparatus for use in x-ray radiography. Specific embodiments can utilize a grid having a plurality of apertures therethrough with optical waveguides positioned in the apertures. The optical waveguides can incorporate a scintillating material, preferably throughout, that absorbs incident x-ray radiation and emits light that is then guided by the optical waveguide. In a specific embodiment, x-ray radiation incident on a first end of the aperture is absorbed by the scintillating material in the optical waveguide and light is emitted by the same scintillating material, a portion of which is guided by the optical waveguide to a second end of the aperture. In addition, secondary electrons created by absorption of the x-ray radiation by the scintillating material can be absorbed by the scintillating material to create more light such that a magnification effect can occur. The light exiting the second end of the aperture can then be detected. | 05-12-2011 |
| 20110109347 | SELF-POWERED COMPARATOR - Embodiments of the invention relate to an input-powered comparator. Embodiments of the invention also pertain to an active diode that includes an input-powered comparator and a switch. In a specific embodiment, the input-powered comparator only consumes power when an input source provides sufficiently high voltage. Embodiments of the active diode can be used in an energy harvesting system. The comparator can be powered by the input and the system can be configured such that the comparator only consumes power when the input is ready to provide power to the load or energy storage element. In a specific embodiment, when there is no input, or the input is too low for harvesting, the comparator does not draw any power from the energy storage element (e.g., battery or capacitor) of the system. | 05-12-2011 |
| 20110084237 | PROTON CONDUCTING MEMBRANES FOR HYDROGEN PRODUCTION AND SEPARATION - In one embodiment, a membrane of proton-electron conducting ceramics that is useful for the conversion of a hydrocarbon and steam to hydrogen has a porous support of M′-Sr | 04-14-2011 |
| 20110078821 | HEAT RESISTANT PLANTS AND PLANT TISSUES AND METHODS AND MATERIALS FOR MAKING AND USING SAME - The subject invention concerns materials and methods for providing plants or plant tissue with increased resistance to heat conditions and/or increased starch biosynthesis. Increased resistance of a plant or plant tissue to heat conditions provides for decreased yield losses as compared to the yield losses generally observed at elevated temperatures. One aspect of the invention concerns polynucleotides that encode a mutant plant small subunit of AGPase. The subject invention also comprises a mutant plant small subunit of AGPase encoded by a polynucleotide of the invention. The subject invention also concerns plants comprising a polynucleotide of the invention and method for making the plants. | 03-31-2011 |
| 20110076497 | COATED CARBON NANOTUBES AND METHOD FOR THEIR PREPARATION - Polymer coated carbon nanotube (NT) particles having NT particles with a solid polymer layer around the surface of each NT particle are presented. The NT particles can be isolated NTs or can include bundles of NTs. A method for preparation of the polymer coated carbon NT particles involves an aqueous dispersion that has a water insoluble first monomer contained in an emulsion-like nano-environment about the NT particles that undergoes an interfacial polymerization with a water soluble second monomer added to the dispersion. | 03-31-2011 |
| 20110074381 | SENSORS USING HIGH ELECTRON MOBILITY TRANSISTORS - Embodiments of the invention include sensors comprising high electron mobility transistors (HEMTs) with capture reagents on a gate region of the HEMTs. Example sensors include HEMTs with a thin gold layer on the gate region and bound antibodies; a thin gold layer on the gate region and chelating agents; a non-native gate dielectric on the gate region; and nanorods of a non-native dielectric with an immobilized enzyme on the gate region. Embodiments including antibodies or enzymes can have the antibodies or enzymes bound to the Au-gate via a binding group. Other embodiments of the invention are methods of using the sensors for detecting breast cancer, prostate cancer, kidney injury, glucose, metals or pH where a signal is generated by the HEMT when a solution is contacted with the sensor. The solution can be blood, saliva, urine, breath condensate, or any solution suspected of containing any specific analyte for the sensor. | 03-31-2011 |
| 20110068372 | SENSORS USING HIGH ELECTRON MOBILITY TRANSISTORS - Embodiments of the invention include sensors comprising AlGaAs/GaAs high electron mobility transistors (HEMTs), inGaP/GaAs HEMTs. InAlAs/InGaAs HEMTs, AlGaAs/InGaAs PHEMTs, InAlAs/InGaAs PHEMTs, Sb based HEMTs, or InAs based HEMTs, the HEMTs having functionalization at a gate surface with target receptors. The target receptors allow sensitivity to targets (or substrates) for detecting breast cancer, prostate cancer, kidney injury, chloride, glucose, metals or pEI where a signal is generated by the HEMI when a solution is contacted with the sensor. The solution can be blood, saliva, urine, breath condensate, or any solution suspected of containing any specific analyte for the sensor. | 03-24-2011 |
| 20110062986 | LOGIC BASED ON THE EVOLUTION OF NONLINEAR DYNAMICAL SYSTEMS - A logic gate implements logical expressions. A least one logic gate input receives at least one input logic gate signal and at least one control signal. At least one output for produces a logic gate output signal. A nonlinear updater operates as a dynamically configurable element to produce a plurality of different logic gates as selected by the control signal. The nonlinear updater includes a nonlinear updater output. The nonlinear updater is configured to apply a nonlinear function to the input logic gate signal to produce the nonlinear updater output signal representing a logical expression being implemented by one of the plurality of different logic gates on the input logic gate signal. A comparator includes a comparator input that is adapted to receive a reference threshold value for producing the logical gate output signal based on a comparison of the nonlinear output signal to the reference threshold value. | 03-17-2011 |
| 20110062860 | INTERDIGITATED ELECTRODE DUAL ELECTROEMISSIVE/ELECTROCHROMIC DEVICES - A dual electrochromic/electroluminescent (EC/EL) device of at least one pixel includes an interdigitated electrode where an electroactive layer is dispersed on and between the digits of the two electrodes of the interdigitated electrode. The electroactive layer is in contact with an electrolyte layer that also contacts a third electrode. The device acts as an electroluminescence device when an electrical bias between the two electrodes of the interdigitated electrode is established. The device acts as an electrochromic device when the electrical bias is established between the combined electrodes of the interdigitated electrode and the third electrode. | 03-17-2011 |
| 20110052495 | USE OF FULLERENES IN PHOTOACOUSTIC IMAGING - Fullerenes, when irradiated with electromagnetic radiation, generate acoustic waves. A photoacoustic tomography method using a material comprising fullerenes is disclosed that includes irradiating the material with a radiation beam such as a laser. The resultant photoacoustic effect produced by the material is detected by at least one detector. A photoacoustic tomography system using a material comprising fullerenes is also described. | 03-03-2011 |
| 20110046731 | METHOD AND APPARATUS FOR IN-SITU ADJUSTABILITY OF A MIDDLE EAR PROSTHESIS - Embodiments of the present invention provide a middle ear prosthesis that can be adjusted in situ. Embodiments of the invention also relate to a method for adjusting a middle ear prosthesis in situ. In specific embodiments, the middle ear prosthesis can be inserted into the middle ear of a patient during surgery and then, after the surgery, the length of, or distance between the end resting on the malleus and the end resting on the stapes, can be adjusted without the need to touch the prosthesis through a surgical intervention. A middle ear prosthesis can include a first element | 02-24-2011 |
| 20110046330 | BLACK SOLUBLE CONJUGATED POLYMERS WITH HIGHLY TRANSMISSIVE OXIDIZED STATE - A soluble donor-acceptor electrochromic polymer (DA-ECP) is prepared that absorbs light throughout at least the majority of the visible range and is essentially black to the human eye when in the neutral state, but is highly transmissive when electrochemically doped. The conjugated polymer has acceptor units separated by sequences of a plurality of donor units. The sequences can be monodispersed or polydispersed. The DA-ECP is prepared by the polycondensation of a plurality of at least one donor-acceptor oligomer (DA-oligomer) that has at least one internal acceptor repeating unit and at least one donor repeating unit on all termini of the oligomer, and optionally, a plurality of at least one donor monomer and/or donor oligomer. | 02-24-2011 |
| 20110045600 | OXYGEN AND CARBON DIOXIDE SENSING - A high electron mobility transistor (HEMT) capable of performing as a CO | 02-24-2011 |
| 20110042683 | CRACK FREE MULTILAYERED DEVICES, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is an article comprising a substrate; an interlayer comprising aluminum nitride, gallium nitride, boron nitride, indium nitride or a solid solution of aluminum nitride, gallium nitride, boron nitride and/or indium nitride; the interlayer being directly disposed upon the substrate and in contact with the substrate; where the interlayer comprises a columnar film and/or nanorods and/or nanotubes; and a group-III nitride layer disposed upon the interlayer; where the group-III nitride layer completely covers a surface of the interlayer that is opposed to a surface in contact with the substrate; the group-III nitride layer being free from cracks. | 02-24-2011 |
| 20110040103 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES - The subject invention pertains to pentafluorosulfonyl (SF5) substituted pyrroles, thiophenes, 3-pyrrolines and 2,5-dihydrothiophenes, as well as methods for their synthesis. | 02-17-2011 |
| 20110032529 | UNIVERSAL WAVELENGTH CALIBRATION SOURCE USING A STABLE MONOLITHIC INTERFEROMETER - Calibration of an arbitrary spectrometer can use a stable monolithic interferometer as a wavelength calibration standard. Light from a polychromatic light source is input to the monolithic interferometer where it undergoes interference based on the optical path difference (OPD) of the interferometer. The resulting wavelength-modulated output beam is analyzed by a reference spectrometer to generate reference data. The output beam from the interferometer can be provided to an arbitrary spectral instrument. Wavelength calibration of the arbitrary spectral instrument may then be performed based on a comparison of the spectral instrument output with the reference data. By appropriate choice of materials for the monolithic interferometer, a highly stable structure can be fabricated that has a wide field and/or is thermally compensated. Because the interferometer is stable, the one-time generated reference data can be used over an extended period of time without re-characterization. | 02-10-2011 |
| 20110032512 | FLOATING-ELEMENT SHEAR-STRESS SENSOR - A shear-stress sensing system can include a floating element whose displacement can be detected through use of optical measurements. The system can utilize high temperature materials to deliver the optical signal to the structure to be measured, which can also utilize high temperature materials. In one embodiment, an intensity modulation or phase modulation of a reflected signal can be measured to determine the shear stress. In another embodiment, a Moire fringe pattern can be used to determine the shear stress. | 02-10-2011 |
| 20110031430 | SYNTHESIS OF WATER-SOLUBLE ORGANIC NANOPARTICLES AS EPR STANDARD - Novel water soluble paramagnetic organic nanoparticles are formed by a novel method where an organic solution of an organic compound is injected into water under agitation that is maintained for a desired period of time for nanoparticle growth followed by termination of the growth by the addition of an aqueous surfactant solution. The size of the nanoparticles depends on the time between injection and addition of the surfactant solution. In embodiments of the invention, the water soluble paramagnetic organic nanoparticles can be DPPH nanoparticles, DPPH nanoparticles doped with DPPH-H, or core/shell nanoparticles where a DPPH core is covered by a DPPH-H shell. | 02-10-2011 |
| 20110031403 | METHOD AND APPARATUS FOR INFRARED DETECTION AND DISPLAY - Embodiments of the subject invention relate to a method and apparatus for infrared (IR) detection. Organic layers can be utilized to produce a phototransistor for the detection of IR radiation. The wavelength range of the IR detector can be modified by incorporating materials sensitive to photons of different wavelengths. Quantum dots of materials sensitive to photons of different wavelengths than the host organic material of the absorbing layer of the phototransistor can be incorporated into the absorbing layer so as to enhance the absorption of photons having wavelengths associated with the material of the quantum dots. A photoconductor structure can be used instead of a phototransistor. The photoconductor can incorporate PbSe or PbS quantum dots. The photoconductor can incorporate organic materials and part of an OLED structure. A detected IR image can be displayed to a user. Organic materials can be used to create an organic light-emitting device. | 02-10-2011 |
| 20110031399 | METHOD AND APPARATUS FOR INFRARED DETECTION AND DISPLAY - Embodiments of the subject invention relate to a method and apparatus for infrared (IR) detection. Organic layers can be utilized to produce a phototransistor for the detection of IR radiation. The wavelength range of the IR detector can be modified by incorporating materials sensitive to photons of different wavelengths. Quantum dots of materials sensitive to photons of different wavelengths than the host organic material of the absorbing layer of the phototransistor can be incorporated into the absorbing layer so as to enhance the absorption of photons having wavelengths associated with the material of the quantum dots. A photoconductor structure can be used instead of a phototransistor. The photoconductor can incorporate PbSe or PbS quantum dots. The photoconductor can incorporate organic materials and part of an OLED structure. A detected IR image can be displayed to a user. Organic materials can be used to create an organic light-emitting device. | 02-10-2011 |
| 20110014596 | DEVICES AND METHODS FOR IMPLEMENTING ENDOSCOPIC SURGICAL PROCEDURES AND INSTRUMENTS WITHIN A VIRTUAL ENVIRONMENT - Devices and methods are provided for combining the handle of a surgical instrument with a force feedback generator, able to create resistance to motion similar to that encountered in a real operating environment. The working end of the surgical instrument is recreated in a virtual environment and manipulated by the modified handle through the force feedback generator. Actions of the instrument handle modify a model and display of the virtual environment and transmit a haptic response back to the handle. The devices and methods provide a means for repeatedly performing maneuvers that accurately simulate the actual instrument, but in the virtual environment. The virtual environment is modeled to accurately simulate the use of the instrument including manipulation of and collisions with other virtual objects, such as surgical thread or internal tissues. Training and assessment tools are also provided that coach or assess a user's proficiency with the instrument. | 01-20-2011 |
| 20110003967 | SOLUBLE ALTERNATING DONOR-ACCEPTOR CONJUGATED POLYMER ELECTROCHROMES - Embodiments of the invention are directed to alternating donor-acceptor (DA) polymers that are soluble and display a blue or green neutral state that oxidizes to a transmissive state for use as an electrochromic polymer. The D units have 3,4-dioxythiophene, 3,6-dialkoxythieno[3,2-b]thiophene or 3,5-dialkoxy-dithieno[3,2-b:2′,3′-d]thiophene groups. Embodiments of the invention are directed to a method for preparation of the alternating DA polymeric sequences of the DA polymers by a cross-condensation of a nucleophilic acceptor monomer and an electrophilic donor monomer. | 01-06-2011 |
| 20110003252 | FUNCTIONALIZED FULLERENES FOR NANOLITHOGRAPHY APPLICATIONS - A method for electron beam nanolithography without the need for development step involves depositing a film of a resist comprising functionalized fullerenes on a substrate, and writing features by exposure to an electron beam with an accelerating voltage and dose rate sufficient to promote heating or thermal degradation of the functionalized fullerene in the irradiated volume such that a pattern is generated without a subsequent development step or with an aqueous developer. Lithographic features of about 1 nm or greater can be formed. | 01-06-2011 |
| 20110003142 | NANOPARTICLE SOL-GEL COMPOSITE HYBRID TRANSPARENT COATING MATERIALS - A composite hybrid coating having a thick highly transparent hard coating with excellent barrier properties is described. The hybrid coating is the gelled dispersion of nanoparticles in a sol with least one hydrolyzable silane and at least one hydrolyzable metal oxide precursor. In one embodiment a composite hybrid coating is formed by the curing of a dispersion formed by the addition of a suspension of boehmite nanoplatelets in a sol prepared by the hydrolysis of tetraethoxysilane, γ-glycidoxypropyltrimethoxysilane and titanium tetrabutoxide in ethanol. A plastic substrate can be coated with the dispersion and the dispersion gelled to a thickness of at least 5 μm with heating to less than 150° C. | 01-06-2011 |
| 20110000781 | OPTICAL RELEASE OF HYDROGEN FROM FUNCTIONALIZED FULLERENES AS STORAGE MATERIALS - A method to release hydrogen from a material comprising hydrogen fixed fullerenes involves irradiating the hydrogen fixed fullerenes with electromagnetic radiation of sufficient intensity to release hydrogen rapidly upon irradiation. The intensity of the irradiation and/or the area of irradiation can be adjusted to control the rate and extent of hydrogen release. The hydrogen depleted material comprising hydrogen fixed fullerene can be hydrogenated to regenerate the material. | 01-06-2011 |
| 20100330261 | METHOD OF ATTACHING AN ANTIMICROBIAL CATIONIC POLYELECTROLYTE TO THE SURFACE OF A SUBSTRATE - A method of bonding an antimicrobial cationic polyelectrolyte to the surface of a substrate is described, wherein the antimicrobial thus attached to the substrate provides the substrate with antimicrobial properties, and at least a portion of the bonded antimicrobial is substantially non-leachable during normal conditions of use and storage. A method of manufacturing an antimicrobial material is described which comprises exposure of the substrate to a solution of antimicrobial cationic polyelectrolyte, followed by drying the exposed substrate thoroughly to impart a non-leaching property to at least a portion of the antimicrobial cationic polyelectrolytes. | 12-30-2010 |
| 20100330146 | CONTACT LENSES FOR EXTENDED RELEASE OF BIOACTIVE AGENTS CONTAINING DIFFUSION ATTENUATORS - An appliance for the delivery of at least one bioactive agent to the eye has at least one diffusion attenuator within a hydrophilic or silicone-hydrogel contact lens. The bioactive agent can be a drug or a nutraceutical. The diffusion attenuator can be a plurality of solid particles or phase separated liquid aggregates within at least one continuous phase of the lens where the diffusion attenuators promote a tortuous path for the diffusion of the bioactive agent to mediate the rate by which the bioactive agent diffuses from the contact lens. The diffusion attenuator can be homogeneously dispersed throughout at least one continuous phase of the lens to modify the diffusivity of the bioactive agent through that phase. The diffusion attenuator can have little or no affinity for the bioactive agent or can be miscible with the bioactive agent. The diffusion attenuator can be incorporated while forming the contact lens by polymerization of a monomer mixture containing the diffusion attenuator. For liquid diffusion attenuators, the liquid can be co-absorbed with a solvent into the lens followed by removal of the solvent, where the bioactive agent can be co-absorbed or subsequently absorbed after the loading of the diffusion attenuator. The diffusion attenuator can be Vitamin E. | 12-30-2010 |
| 20100329043 | Two-Transistor Floating-Body Dynamic Memory Cell - Embodiments relate to a two-transistor (2T) floating-body cell (FBC) for embedded-DRAM applications. Further embodiments pertain to a floating-body/gate cell (FBGC), which yields reduction in power dissipation, in addition to better signal margin, longer data retention, and higher memory density. | 12-30-2010 |
| 20100326891 | SEPARATION OF CARBON NANOTUBE BUNDLES VIA INTERFACIAL TRAPPING - In embodiments of the invention, bundles of carbon nanotubes are separated from individual nanotubes via interfacial trapping of bundled carbon nanotube bundles at an emulsion interface between suspension-phase and a solution-phase. The separation method comprises dispersing a mixture of individual and bundled carbon nanotubes in a solution comprising surfactant; adding at least one solvent to the surfactant solution to form a two-phase mixture; agitating the two-phase mixture to form an emulsion interface between the solution-phase and a suspension-phase, where nanotube bundles selectively segregate to the emulsion interface. Single-walled carbon nanotube suspensions exhibit strong fluorescence, which can be used to assess the degree of separation and determine if a repeated extraction of any remaining bundled carbon nanotubes remaining in the suspension-phase is desired. In another embodiment of the invention, separation of carbon nanotubes by type is carried out by interfacial trapping. | 12-30-2010 |
| 20100323258 | ELECTRIC-FIELD ENHANCED PERFORMANCE IN CATALYSIS AND SOLID-STATE DEVICES INVOLVING GASES - Electrode configurations for electric-field enhanced performance in catalysis and solid-state devices involving gases are provided. According to an embodiment, electric-field electrodes can be incorporated in devices such as gas sensors and fuel cells to shape an electric field provided with respect to sensing electrodes for the gas sensors and surfaces of the fuel cells. The shaped electric fields can alter surface dynamics, system thermodynamics, reaction kinetics, and adsorption/desorption processes. In one embodiment, ring-shaped electric-field electrodes can be provided around sensing electrodes of a planar gas sensor. | 12-23-2010 |
| 20100318506 | NON-LINEAR DYNAMICAL SEARCH ENGINE - A dynamical search engine for searching a database is also provided. The dynamical search engine includes an array of nonlinear dynamical elements. The nonlinear dynamical element information items in a manner that confines the state of each element on a fixed point and uniquely encodes the information items. The dynamical search engine also includes a controller for controlling electrical signals supplied to elements of the array in a predetermined sequence. One supplied signal increases a state value of each element of the array by a quantity defining a search key that corresponds to a searched-for information item. A subsequently supplied signal updates the state value of each element of the array by performing a nonlinear folding of each state value based on a predetermined pivot. | 12-16-2010 |
| 20100317537 | BIOPHYSICAL PARAMETERS FOR SYSTEMS BIOLOGY - The invention relates to apparatus and methods for studying intracellular rheology. The invention further relates to use of such apparatus and methods to screen for potentially therapeutic molecules that give rise to rheological effects within a cell. As one example, the disclosed ballistic intracellular nanorheology (BIN) apparatus and methods may be employed in a high-throughput screen to identify mediators or inhibitors of the cytoskeletal modifications involved in cancer metastasis. | 12-16-2010 |
| 20100317041 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-16-2010 |
| 20100311080 | WATER-SOLUBLE NANOCRYSTALS THROUGH DUAL-INTERACTION LIGANDS - A dual-interaction ligand for rendering otherwise hydrophobic nanoparticles water soluble or suspendable has a hydrophilic base with a plurality of hydrophilic segments extending from a core of the base, where at least one segment or the core contains a hydrophobic groups capable of forming van der Waal interaction between hydrophobic groups of the dual-interaction ligand and other hydrophobic ligands, and at least one complexing functionality to complex a metal atom or ion of a nanoparticle. The dual-interaction ligands can be combined with hydrophobic nanoparticles, where the dual-interaction ligands can displace some or all of the hydrophobic ligands of the hydrophobic nanoparticles, to form a nanoparticle-dual interaction ligand complex that can be dissolved or dispersed readily in an aqueous solution. The dual interaction ligand can be functionalized to attach an antibody or other biomolecules such that the nanoparticle dual-interaction ligands complexes can contain biomolecules. Such biomolecules modified nanoparticle dual-interaction ligands can be used for sensing, labeling, optical imaging, magnetic resonance imaging, cell separation, and treatment of diseases. | 12-09-2010 |
| 20100310622 | DRY EYE TREATMENT BY PUNCTA PLUGS - A punctal plug and method of treating dry eyes are provided. The punctal plug has two or three layer structure and contains at least one drug, for treating conditions such as dry eyes contained in a core, a potion of which is covered by a drug impermeable shell such that drug can radially diffuse from the core. The punctal plug can be inserted into a patient's upper punctum, lower punctum, or both to deliver the drug for an extended period of time. The drug for treating dry eyes can be, for example, cyclosporine A. The plug can also be used for extended delivery of ophthalmic drugs. | 12-09-2010 |
| 20100308359 | HIGH LIGHT EXTRACTION EFFICIENCY SOLID STATE LIGHT SOURCES - A solid state light source includes a substrate having a top surface and a bottom surface, and at least one optically active layer on the top surface of the substrate. At least one of the top surface, the bottom surface, the optically active layer or an emission surface on the optically active layer includes a patterned surface that includes a plurality of tilted surface features that have a high elevation portion and a low elevation portion that define a height (h), and wherein the plurality of tilted surface features define a minimum lateral dimension (r). The plurality of tilted surface features provide at least one surface portion that has a surface tilt angle from 3 to 85 degrees. The patterned surface has a surface roughness <10 nm rms, and h/r is ≧0.05. | 12-09-2010 |
| 20100307150 | ELECTROTHERMAL MICROACTUATOR FOR LARGE VERTICAL DISPLACEMENT WITHOUT TILT OR LATERAL SHIFT - A microactuator for displacing a platform vertically with respect to a substrate includes a first rigid frame, a first flexible bimorph beam connecting the first frame to the substrate, a second rigid frame, a second flexible bimorph beam connecting the second frame to the first frame, and a third flexible bimorph beam connecting a platform to the second frame. Activation of the first, second, and third flexible bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A microactuator assembly includes a substrate, a plurality of first rigid frames, a plurality of first flexible bimorph beams, a plurality of second rigid frames, a plurality of second flexible bimorph beams, a platform, and a plurality of third flexible bimorph beams. Activation of the first, second, and third bimorph beams allows vertical displacement of the platform with respect to the substrate, with negligible lateral shift. A further embodiment with four identical such microactuators oriented at four sides of the platform, can achieve 1D or 2D angular scanning of the mirror plate by the activation of 1 or 2 adjacent microactuators. | 12-09-2010 |
| 20100305212 | THERAPEUTIC COMPOUNDS - The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C disorders, including diseases and disorders mediated by GPCRs. | 12-02-2010 |
| 20100292465 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS - Novel N-heterocyclic carbene ligand precursors, N-heterocyclic carbene ligands and N-heterocyclic metal-carbene complexes are provided. Metal-carbene complexes comprising N-heterocyclic carbene ligands can be chiral, which are useful for catalyzing enantioselective synthesis. Methods for the preparation of the N-heterocyclic carbene ligands and N-heterocyclic metal-carbene complexes are given. | 11-18-2010 |
| 20100290577 | NUCLEAR REACTOR HAVING EFFICIENT AND HIGHLY STABLE THERMAL TRANSFER FLUID - A pressurized water nuclear reactor (PWNR) | 11-18-2010 |
| 20100285012 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS - The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8). | 11-11-2010 |
| 20100278933 | KINASE INHIBITOR COMPOUNDS - The invention relates to kinase inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating disorders, especially cancer. | 11-04-2010 |
| 20100265562 | DUAL ACTIVE FILM ELECTROCHROMIC DISPLAY DEVICE - A dual active electrochromic device is a combination of at least two working electrodes that contain electrochromic materials and at least one counter electrode where the potentials between each working electrode and a counter electrode are independently supplied. No more than one electrode is reflective. The color of the device results from the additive color of the electrochromic materials and varies according to the potentials applied independently. The electrochromic materials can be electrochromic polymers that are deposited as film on substrates to form the working electrodes. The electrochromic device can be used for display or window applications. | 10-21-2010 |
| 20100264900 | Multifunctional Potentiometric Gas Sensor Array With an Integrated Temperature Control and Temperature Sensors - Embodiments of the subject invention relate to a gas sensor and method for sensing one or more gases. An embodiment incorporates an array of sensing electrodes maintained at similar or different temperatures, such that the sensitivity and species selectivity of the device can be fine tuned between different pairs of sensing electrodes. A specific embodiment pertains to a gas sensor array for monitoring combustion exhausts and/or chemical reaction byproducts. An embodiment of the subject device related to this invention operates at high temperatures and can withstand harsh chemical environments. Embodiments of the device are made on a single substrate. The devices can also be made on individual substrates and monitored individually as if they were part of an array on a single substrate. The device can incorporate sensing electrodes in the same environment, which allows the electrodes to be coplanar and, thus, keep manufacturing costs low. Embodiments of the device can provide improvements to sensitivity, selectivity, and signal interference via surface temperature control. | 10-21-2010 |
| 20100264334 | EXCITATION-INTENSITY-DEPENDENT, COLOR-TUNABLE, DUAL EMITTING NANOCRYSTALS - An embodiment of the invention is a device for photo-stimulated color emission having at least one plurally doped semiconducting nanoparticle comprising at least one semiconducting material and a plurality of at least one dopant coupled with an irradiation source such that the plurally doped semiconducting nanoparticle emit electromagnetic radiation at two or more wavelengths where the intensities of the emissions depend on the intensity of the irradiation. In an embodiment of the invention, the plurally doped semiconducting nanoparticle can be a doped core/shell nanoparticle where the plurality of dopants can reside in exclusively the core, exclusively the shell, or in both the core and shell. | 10-21-2010 |
| 20100264306 | PNEUMATIC ION BEAM FOCUSING IN HIGH-FIELD ASYMMETRIC WAVEFORM ION MOBILITY SPECTROMETRY (FAIMS) - A FAIMS device for separating ions has a pair of electrodes for providing a compensation voltage and an asymmetric waveform that are separated and insulated where at least one porous spacer reside in the proximity of the analyzer region of the FAIMS cell. The porous spacers allow a focusing gas to flow into the analyzer region to provide pneumatic focusing of the ions traversing the analyzer region to improve the ion transmission. | 10-21-2010 |
| 20100261178 | High Throughput Assays for Inhibitors and Activators of PAQR Receptors - The subject invention provides methods of screening compounds or ligands that interact with human and/or non-human PAQR receptors or fungal osmotin receptors. These methods utilize a colorimetric assay to ascertain whether a compound binds to and activates a PAQR receptor or the osmotin receptor. | 10-14-2010 |
| 20100260977 | CHEMICAL MECHANICAL FABRICATION (CMF) FOR FORMING TILTED SURFACE FEATURES - A method of chemical-mechanical fabrication (CMF) for forming articles having tilted surface features. A substrate is provided having a patterned surface including two different layer compositions or a non-planar surface having at least one protruding or recessed feature, or both. The patterned surface are contacted with a polishing pad having a slurry composition, wherein a portion of surface being polished polishes at a faster polishing rate as compared to another portion to form at least one tilted surface feature. The tilted surface feature has at least one surface portion having a surface tilt angle from 3 to 85 degrees and a surface roughness<3 nm rms. The tilted surface feature includes a post-CMF high elevation portion and a post-CMF low elevation portion that defines a maximum height (h), wherein the tilted surface feature defines a minimum lateral dimension (r), and h/r is ≧0.05. | 10-14-2010 |
| 20100258528 | CHEMICAL MECHANICAL POLISHING OF SILICON CARBIDE COMPRISING SURFACES - Slurry compositions and chemically activated CMP methods for polishing a substrate having a silicon carbide surface using such slurries. In such methods, the silicon carbide surface is contacted with a CMP slurry composition that comprises i) a liquid carrier and ii) a plurality of particles having at least a soft surface portion, wherein the soft surface portion includes a transition metal compound that provides a Mohs hardness ≦6, and optionally iii) an oxidizing agent. The oxidizing agent can include a transition metal. The slurry is moved relative to the silicon carbide comprising surface, wherein at least a portion of eth silicon carbide surface is removed. | 10-14-2010 |
| 20100254911 | MULTIMODAL NANOPARTICLES FOR NON-INVASIVE BIO-IMAGING - Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging. | 10-07-2010 |
| 20100252434 | Bio-Sensor Using Gated Electrokinetic Transport - Embodiments of the present invention provide a method and apparatus for selective electrokinetic separation. In an embodiment, a local gate electric field is applied to a voltage-gated nanochannel filled with an aqueous solution. Additionally, a surface charge may be present on the walls of the nanochannel. This local gate electric field shows a selective quenching feature of ionic density and behaves as a potential shield against selective charge from entering the nanochannel while facilitating transport of the opposite charge. Embodiments of the subject method can also be used to enhance osmotic diffusion of selective electrolytes through biological cells. Specific embodiments can be useful as a biosensor since most biological cells contain an aqueous solution. A surface charge and local gate electric field can be applied to a biological cell to selectively separate molecules, such as proteins or ions. Embodiments of the subject method can be used in conjunction with a field effect transistor to provide more efficient electrokinetic transport. In an embodiment, the subject invention provides an improved field effect transistor. By applying a surface charge to the walls of a nanochannel in a semiconductor material, the electric field of the transistor gives more selective separation of charged carriers. | 10-07-2010 |
| 20100250217 | Docking Pose Selection Optimization via NMR Chemical Shift Perturbation Analysis - Using NMRScore to generate an RMSD and evaluating whether the RMSD is below 1 ppm, in order to indicate that a docking software generated pose is a good match with the experimental assessment of a paradigm protein target and paradigm ligand, and therefore that the pose will be useful and accurate for the same target and similar ligands, or similar targets and the same ligands. | 09-30-2010 |
| 20100248385 | MULTI-ACCEPTOR MOLECULAR PROBES AND APPLICATIONS THEREOF - An oligonucleotide-based molecular probe includes at least one pin loop, the pin loop including a loop sequence complementary to a target sequence. A first stem sequence is attached to one end of the pin loop, the first stem having at least one fluorescent label attached thereto. A second stem sequence is attached to the other end of the pin loop. The second stem has a plurality of quencher molecules attached thereto. | 09-30-2010 |
| 20100241010 | Complex Signal Demodulation and Angular Demodulation for Non-contact Vital Sign Detection - Methods for recovering a detected signal in non-contact vital sign detection are provided. According to one embodiment, a detected reflected signal from a non-contact vital sign detection system can be received and provided along I channel and Q channel signal lines. A complex signal S(t) can then be reconstructed from the I channel and Q channel signal lines through complex signal demodulation. A Fourier transform can be used to obtain the detected signal's spectrum for spectrum analysis. Angular demodulation can be used to recover the information corresponding to original body movement. The complex signal demodulation and angular demodulation techniques used to provide information to determine original body movement are capable of avoiding the null detection point without limitations on frequency tuning or channel selection. | 09-23-2010 |
| 20100237336 | NANOTUBE ENABLED, GATE-VOLTAGE CONTROLLED LIGHT EMITTING DIODES - Embodiments of the invention relate to vertical field effect transistor that is a light emitting transistor. The light emitting transistor incorporates a gate electrode for providing a gate field, a first electrode comprising a dilute nanotube network for injecting a charge, a second electrode for injecting a complementary charge, and an electroluminescent semiconductor layer disposed intermediate the nanotube network and the electron injecting layer. The charge injection is modulated by the gate field. The holes and electrons, combine to form photons, thereby causing the electroluminescent semiconductor layer to emit visible light. In other embodiments of the invention a vertical field effect transistor that employs an electrode comprising a conductive material with a low density of states such that the transistors contact barrier modulation comprises barrier height lowering of the Schottky contact between the electrode with a low density of states and the adjacent semiconductor by a Fermi level shift. | 09-23-2010 |
| 20100236630 | CHEMICAL VAPOR DEPOSITION OF CuInxGa1-x(SeyS1-y)2 THIN FILMS AND USES THEREOF - The subject application relates to a chemical vapor (CV) deposition technique to form CuIn | 09-23-2010 |
| 20100227934 | THERAPEUTIC COMPOUNDS AND METHODS OF USE - The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C disorders, including diseases and disorders mediated by GPCRs. | 09-09-2010 |
| 20100223237 | LOSSLESS DATA COMPRESSION AND REAL-TIME DECOMPRESSION - A method, information processing system, and computer program storage product store data in an information processing system. Uncompressed data is received and the uncompressed data is divided into a series of vectors. A sequence of profitable bitmask patterns is identified for the vectors that maximizes compression efficiency while minimizes decompression penalty. Matching patterns are created using multiple bit masks based on a set of maximum values of the frequency distribution of the vectors. A dictionary is built based upon the set of maximum values in the frequency distribution and a bit mask savings which is a number of bits reduced using each of the multiple bit masks. Each of the vectors is compressed using the dictionary and the matching patterns with having high bit mask savings. The compressed vectors are stored into memory. Also, an efficient placement is developed to enable parallel decompression of the compressed codes. | 09-02-2010 |
| 20100221225 | COMPOSITIONS AND METHODS FOR TREATING GLYCOGEN STORAGE DISEASES - Compositions and methods of use include therapeutically effective molecules for treatment of diseases in mammals including glycogen storage diseases (e.g., Pompe disease). These compositions in combination with various routes and methods of administration result in targeted uptake and expression of therapeutic molecules in specific organs, tissues and cells resulting in correction of a disease such as a glycogen storage disease (e.g., Pompe disease). | 09-02-2010 |
| 20100219862 | RECONFIGURABLE AND RELIABLE LOGIC CIRCUIT ELEMENTS THAT EXPLOIT NONLINEARITY AND NOISE - A logic gate is adapted to implement logical expressions. The logic gate includes at least one input that is adapted to receive an input signal and at least one control signal. At least one of the input signal and the control signal is a noise signal. At least one output is adapted to produce an output signal. A nonlinear updater operates as a dynamically configurable element and produces multiple different logic gates as selected by the control signal based at least in part on the noise signal. The nonlinear updater is electrically coupled to the input and is also electrically coupled to the output. The nonlinear updates is configured to apply a nonlinear function to the input signal in response to the control signal to produce the output signal representing a logical expression being implemented by one of the multiple different logic gates on the input signal. | 09-02-2010 |
| 20100219858 | LOGIC BASED ON THE EVOLUTION OF NONLINEAR DYNAMICAL SYSTEMS - A logic gate implements logical expressions. A least one logic gate input receives at least one input logic gate signal and at least one control signal. At least one output for produces a logic gate output signal. A nonlinear updater operates as a dynamically configurable element to produce a plurality of different logic gates as selected by the control signal. The nonlinear updater includes a nonlinear updater output. The nonlinear updater is configured to apply a nonlinear function to the input logic gate signal to produce the nonlinear updater output signal representing a logical expression being implemented by one of the plurality of different logic gates on the input logic gate signal. A comparator includes a comparator input that is adapted to receive a reference threshold value for producing the logical gate output signal based on a comparison of the nonlinear output signal to the reference threshold value. | 09-02-2010 |
| 20100213086 | Method and Apparatus for Tracking Transported Items Using RFID Tags - A method and apparatus for tracking transported items using RFID tags are provided. A tote for transporting RFID tagged items includes a body capable of enclosing one or more RFID tagged items. RF reflective and/or absorbent material is positioned to inhibit RF signals from reaching the enclosed RFID tagged items from outside the body. A portion of a wall of the tote or a sleeve for insertion into the tote can be free of reflective and/or absorbent material to allow RF signals to be sent into, and exit, the tote. The RF reflective and/or absorbent material can be provided with or without texture. | 08-26-2010 |
| 20100211035 | Antimicrobial Bandage Material Comprising Superabsorbent and Non-Superabsorbent Layers - This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial effect. | 08-19-2010 |
| 20100210735 | Modulating the Activity of Nuclear Receptors in Order to Treat Hypoxia-Related Disorders - The subject invention provides methods for treating hypoxia-related conditions by modulating the activity of certain nuclear receptors. Specifically exemplified herein are materials and methods for treating cancer and other pathological conditions involving hypoxia and/or abnormal or excessive neovascularization. | 08-19-2010 |
| 20100208965 | Method and Apparatus for Tomographic Imaging of Absolute Optical Absorption Coefficient in Turbid Media Using Combined Photoacoustic and Diffusing Light Measurements - Embodiments of the invention pertain to methods for imaging a light absorption coefficient distribution. Embodiments of the subject method can be implemented without knowing the strength of incident light in advance and without requiring careful calibrations in the non-scattering medium. Embodiments of the method can combine conventional photoacoustic tomography (PAT) with diffusing light measurements coupled with an optimization procedure based on the photon diffusion equation. Images of absorbing targets as small as 0.5 mm in diameter embedded in a 50 mm diameter background medium can be quantitatively recovered. Small targets with various optical contrast levels relative to the background can be detected well. Embodiments of the subject reconstruction method can include first obtaining the map of absorbed optical energy density. Embodiments can obtain the map of absorbed optical energy density through a model-based reconstruction algorithm that is based on a finite element solution to the photoacoustic wave equation in frequency domain subject to the radiation or absorbing boundary conditions (BCs). The distribution of optical fluence can then be obtained. Embodiments can obtain the distribution of optical fluence using the photon diffusion equation based optimization procedure. The distribution of optical absorption coefficient can then be recovered from the distribution of optical fluence and the absorbed energy density. | 08-19-2010 |
| 20100204587 | Wavelength Division Sensing Method and Apparatus for Doppler Radar Vital Sign Monitoring and Mechanical Vibration Monitoring - Embodiments of the present invention provide a method and a radar system incorporating multiple carrier wavelengths. A multi-carrier radar method and system according to the present invention can be used to realize sensing of complex pattern vibrations using a wavelength division sensing technique. | 08-12-2010 |
| 20100204093 | USE OF HEAT SHOCK ACTIVATORS FOR TISSUE REGENERATION - The present invention generally provides therapeutic compositions and methods for treating a disease, disorder, or injury characterized by a deficiency in cell number. The method involves inducing a heat shock response in tissue or organ effected by disease and recruiting stem cells to repair or regenerate the disease-effected tissue. | 08-12-2010 |
| 20100203602 | Materials and Methods for Efficient Lactic Acid Production - The present invention provides derivatives of | 08-12-2010 |
| 20100201256 | Top-Emission Organic Light-Emitting Devices with Microlens Arrays - Embodiments of the invention can provide organic light-emitting devices (OLEDs) with enhanced outcoupling efficiency. Specific embodiments can enhance the outcoupling efficiency by more than four times. Embodiments of the invention incorporate microlens | 08-12-2010 |
| 20100200091 | Method and Apparatus for Efficient Micropumping - Efficient micro-pumping of gas/liquids is provided. In one embodiment a pipeline of insulative material can be asymmetrically coated with electrodes. The asymmetric coating can affect the flow passage to create straight and swirl pumping effects. The electrodes can include electrode pairs arranged at intervals along the pipeline, each electrode pair being capable of inducing an electrohydrodynamic body force. The electrode pairs can be formed at the same surface, such as along the inner perimeter of the pipeline, and can be powered by steady, pulsed direct, or alternating current. Alternatively, the electrode pairs can be separated by the insulative material of the pipeline, and can be powered with direct or alternating current operating at radio frequency. | 08-12-2010 |
| 20100199385 | Methods and materials for increasing starch biosynthesis in plants - The subject invention concerns materials and methods for providing plants or plant tissue with increased starch biosynthesis. Increased starch biosynthesis provides for increased yield. One aspect of the invention concerns polynucleotides that encode a mutant plant large subunit of AGPase. In one embodiment, a polynucleotide of the invention encodes a plant AGPase large subunit having an amino acid mutation wherein the cysteine amino acid corresponding to amino acid position 424 of wild type maize AGPase large subunit is substituted with an amino acid that results in increased AGPase activity when provided in an AGPase enzyme. In a specific embodiment, the cysteine corresponding to amino acid position 424 of wild type maize AGPase large subunit is substituted with a valine amino acid. The subject invention also comprises a mutant plant large subunit of AGPase encoded by a polynucleotide of the invention. Characterization of kinetic and allosteric properties indicates increased starch yield is provided when the polynucleotides of the invention are expressed in plants such as monocot endosperms. | 08-05-2010 |
| 20100198083 | Random Body Movement Cancellation for Non-Contact Vital Sign Detection - A method and system for cancelling body movement effect for non-contact vital sign detection is described. The method begins with sending on a first electromagnetic wave transceiver a first electromagnetic signal with a first frequency to a first side of a body, such as a person or animal. Simultaneously using a second electromagnetic wave transceiver a second electromagnetic signal is sent with a second frequency to a second side of a body, wherein the first frequency and the second frequency are different frequencies. A first reflected electromagnetic signal reflected back in response to the first electromagnetic wave on the first transceiver is received and a first baseband complex signal is extracted. Likewise a second reflected electromagnetic signal reflected back in response to the second electromagnetic wave on the second transceiver is received and a second baseband complex signal is extracted. The first baseband complex signal is mathematically combined with the second baseband complex signal to cancel out a Doppler frequency drift therebetween to yield a periodic Doppler phase effect. | 08-05-2010 |
| 20100196942 | BIOMARKERS OF LIVER INJURY - Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others. | 08-05-2010 |
| 20100190689 | COMPOSITIONS AND METHODS RELATED TO PROTEIN DISPLACEMENT THERAPY FOR MYOTONIC DISTROPHY - Disclosed are compositions and methods related to the interaction of polyCUG and polyCCUG repeat RNA and proteins that bind to these repetitive RNA sequences. Also disclosed are methods of treating DM1 or DM2 comprising inhibiting the interaction of poly(CUG) | 07-29-2010 |
| 20100184105 | ASSESSING NEURONAL DAMAGE FROM BLOOD SAMPLES - Neuronal damage is detected by providing a biological sample derived from the subject, detecting in the sample the presence of a neurofilament subunits or their breakdown products, and correlating the presence and level of the neurofilament subunits and their breakdown products detected with the degree of neuronal injury. | 07-22-2010 |
| 20100183424 | Electrodynamic Control of Blade Clearance Leakage Loss in Turbomachinery Applications - Electrodynamic control of fluid leakage loss is provided. Embodiments utilize electrohydrodynamic (EHD) principles to control and/or reduce leakage flow in turbomachinery. Electrodes can be used to provide a flow actuation mechanism inside the clearance gap for generating discharge. The electrodes can be positioned to have geometric asymmetry. Embodiments provide the electrodes on a turbine blade. The blade can have a DC power that can function as a square pulsed DC wave with the duty cycle equal to the blade passing frequency and the stator can be grounded. In an embodiment, the stator can have the actuator of the electrode-insulator assembly attached to the inside. In one embodiment, the actuators can be arranged just on the stator or casing. The phase and power supply to individual electrodes can be adapted as needed. In one embodiment, the phase can be lagged for accurate control of leakage flow. The control of the power supply to the electrodes can involve a closed control loop that monitors tip gap size. | 07-22-2010 |
| 20100181901 | INKJET PRINTING OF MICROLENSES FOR PHOTONIC APPLICATIONS - The preparation of microlenses on a substrate and light emitting devices employing microlenses on the surface from which light is emitted is described. The miscrolenses are formed on a surface that has been coated to have functionality that promotes a sufficiently large contact angle of the microlense on the surface and contains functionality for bonding the microlense to the coating. The microlenses are formed on the coating by deposition of a microlense precursor resin as a microdrop by inkjet printing and copolymerizing the resin with the bonding functionality in the coating. The coating can be formed from a mixture of silane coupling agents that contain functionality in some of the coupling agents that is copolymeriable with the resin such that the microlens can be formed and bonded to the surface by photopolymerization. | 07-22-2010 |
| 20100179734 | MANAGING APPLICATION OF AGROCHEMICALS TO PLANTS - A method, information processing system, and computer program storage product apply agrochemicals to plants. A set of user defineable agrochemical application parameters are wirelessly received from a user. A set of data is received from a multiplicity of plant sensors. The set of data includes at least positional data associated with a multiplicity of plants with respect to a set of agrochemical applicators. At least speed data associated with a vehicle coupled to the set of agrochemical applicators is received. The set of agrochemical applicators is instructed to apply one or more agrochemicals to at least one plant in the multiplicity of plants based at least on the set of user defineable agrochemical application parameters that has been wirelessly received, the set of data from a multiplicity of plant sensors, and the speed data. The set of agrochemical applicators apply the one or more agrochemicals to at least one plant. | 07-15-2010 |
| 20100178115 | Systems and Methods for Securing Foundation Members in a Substrate - Systems and methods are provided for establishing and securing a foundation in a substrate. For example, in one embodiment, a pump conveys a first fluid (e.g., water) through a pile member to produce an elongate opening in a substrate, which allows the pile member to be advanced into the substrate. After the pile member has been advanced into the elongate opening in the substrate, a second fluid (e.g., fluidized concrete) is conveyed out of openings on the side (and the bottom) of the pile member to substantially secure the pile member in the elongate opening defined in the substrate. | 07-15-2010 |
| 20100174859 | HIGH CAPACITY CONTENT ADDRESSABLE MEMORY - A set of data is stored in an input space of a kernel content addressable memory. The input space comprising the set of data is transformed into a feature space of higher dimension. The set of data is a set of transformed data within the feature space. An inner product is calculated between the set of transformed data in the feature space using a kernel function. | 07-08-2010 |
| 20100172994 | Nanoparticles for Protection of Cells from Oxidative Stress - The present invention concerns metal oxide semiconductor nanoparticles with free radical scavenging activity, compositions comprising such nanoparticles, methods for their use, and methods for their production. In one aspect, the invention concerns a method for enhancing the survival or viability of transplanted cells, comprising administering an effective amount of metal oxide semiconductor nanoparticles to a target anatomical site of a subject before, during, or after administration of transplant cells to the subject. Preferably, the metal oxide nanoparticle is a cerium oxide (ceria) nanoparticle. | 07-08-2010 |
| 20100170563 | Method and Apparatus for Light Absorption and Charged Carrier Transport - Embodiments of the invention pertain to the use of alloyed semiconductor nanocrystals for use in solar cells. The use of alloyed semiconductor nanocrystals offers materials that have a flexible stoichiometry. The alloyed semiconductor may be a ternary semiconductor alloy, such as A | 07-08-2010 |
| 20100157308 | SINGLE FIBER ENDOSCOPIC FULL-FIELD OPTICAL COHERENCE TOMOGRAPHY (OCT) IMAGING PROBE - A single fiber full-field optical coherence tomography (OCT) imaging probe ( | 06-24-2010 |
| 20100156236 | ROLLER BRUSHES FOR ELECTRICAL MACHINERY, - Various embodiments provide a rotating electrical machine ( | 06-24-2010 |
| 20100150875 | INDEFINITE CULTURE OF HUMAN ADULT GLIA WITHOUT IMMORTALIZATION AND THERAPEUTIC USES THEREOF - Cell culture conditions for the isolation, maintenance, and indefinite expansion of human glia are established favoring the growth of neural precursor cells. Cultured cells proliferate indefinitely, express catalytic telomerase, and retain a non-immortalized phenotype. Compositions allow for the indefinite expansion of non-immortalized neural tissue for bioassay applications and restorative neuroscience. | 06-17-2010 |
| 20100147699 | CONCURRENT O2 GENERATION AND CO2 CONTROL FOR ADVANCED LIFE SUPPORT - A device for the concurrent oxygen generation and control of carbon dioxide for life support system involves two stages, where a first stage removes CO | 06-17-2010 |
| 20100139226 | CERAMIC NANOFIBERS FOR LIQUID OR GAS FILTRATION AND OTHER HIGH TEMPERATURE (> 1000 .degree.C) APPLICATIONS - In accordance with the invention there are devices and processes for making ceramic nanofiber mats and ceramic filters for use in high temperature and in corrosive environments. The process for forming a ceramic filter can include electrospinning a preceramic polymer solution into a preceramic polymer fiber having a diameter from about 10 nm to about 1 micron and forming a preceramic polymer fiber web from the preceramic polymer fiber onto a collector. The process can also include pyrolyzing the preceramic polymer fiber web to form a ceramic nanofiber mat having a diameter less than the diameter of the preceramic polymer fiber, the ceramic nanofiber mat comprising one or more of an oxide ceramic and a non-oxide ceramic such that the ceramic fiber mat can withstand temperature greater than about 1000° C. | 06-10-2010 |
| 20100137346 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS - A pharmaceutical composition comprising a non-toxic effective amount of an actinide decorporation agent and a pharmaceutically acceptable carrier therefore, the actinide decorporation agent comprising a hexacoordinate desferrithiocin analogue capable of chelating an actinide in vivo and a method for removing an actinide from the tissue of a human or nonhuman mammal. | 06-03-2010 |
| 20100127624 | Method and Apparatus for Multibarrier Plasma Actuated High Performance Flow Control - Embodiments of the invention relate to a method and apparatus for plasma actuated high performance flow control. A specific embodiment of a plasma actuator can incorporate a power source; a first electrode in contact with a first dielectric layer and connected to the power source; a second electrode in contact with a second dielectric layer and connected to the power source; and a ground electrode. The power source drives the first electrode with a first ac voltage pattern with respect to the ground electrode and drives the second electrode with a second ac voltage pattern with respect to the ground electrode such that application of the first voltage pattern produces a first plasma discharge in a flow region, and a first electric field pattern in the flow region, and application of the second voltage pattern produces a second plasma discharge in the flow region and a second electric field pattern in the flow region. The first and second electrodes are offset along the direction of flow in the flow region and the first voltage pattern and the second voltage pattern have a phase difference such that the first and second electric fields drive flow in the flow region in different portions of the flow region at different times. | 05-27-2010 |
| 20100126404 | Surface Topographies for Non-Toxic Bioadhesion Control - An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 μm and 100 μm in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article. | 05-27-2010 |
| 20100119755 | METHOD OF PATTERNING A SURFACE AND ARTICLES COMPRISING THE SAME - An article has a curved surface. Disposed upon the curved surface is a plurality of patterns. Each pattern is defined by a plurality of spaced apart features attached to or projected into the curved surface. The plurality of features each have at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent features is about 1 nanometer and about 1 millimeter in at least a portion of the curved surface. The plurality of spaced apart features are represented by a periodic function. | 05-13-2010 |
| 20100119088 | Capacitive Microphone With Integrated Cavity - A capacitive microphone and method of fabricating the same are provided. One or more holes can be formed in a first printed circuit board (PCB). A diaphragm can be surface micro-machined onto an interior surface of the first PCB at a region having the one or more holes. Interface electronics can also be interconnected to the interior surface of the PCB. One or more spacer PCBs can be attached to a second PCB to the first PCB, such that appropriate interconnections between interconnect vias are made. The second PCB and first PCB with spacers in between can be attached so as to create a cavity in which the diaphragm and interface electronics are located. | 05-13-2010 |
| 20100113911 | System for Delivering Conformal Radiation Therapy While Simultaneously Imaging Soft Tissue - A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system. | 05-06-2010 |
| 20100112656 | RE-ENGINEERING BACTERIA FOR ETHANOL PRODUCTION - The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed. | 05-06-2010 |
| 20100110741 | MINIATURE HIGH VOLTAGE/CURRENT AC SWITCH USING LOW VOLTAGE SINGLE SUPPLY CONTROL - Embodiments of the invention pertain to a method and apparatus for planar wireless power transfer where the receiver switches off and/or performs a duty cycle. In an embodiment, the switch can be used in a system that having a high voltage/current solid state switch, without having a high voltage control signal. An embodiment provides a switch that is capable of breaking, or greatly reducing, the connection of the receiver coil and the receiver circuitry in order to enable the receiver to decouple from the power transfer system. This embodiment can allow the transmitter to put out more power to other devices without providing power to the switched device. When the switch is used for a fully charged device, the switching can prevent or reduce damage to the fully charged device. | 05-06-2010 |
| 20100104644 | Compositions and Methods for Treating or Preventing Ophthalmic Disease - Methods are disclosed for treating or preventing ophthalmic conditions related to a toxic visual cycle product. Compounds and compositions useful in these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said the therapeutic and prophylactic methods of the invention. | 04-29-2010 |
| 20100104561 | TYROSINE-MODIFIED RECOMBINANT rAAV VECTOR COMPOSITIONS AND METHODS FOR USE - Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors. | 04-29-2010 |
| 20100102174 | Wingless Hovering Of Micro Air Vehicle - Embodiments of the subject invention relate to a Wingless Hovering Micro Air Vehicle (WHOMAV) and its Power Source Unit (PSU). Embodiments can operate at reasonable power levels for hovering and withstanding expected wind gusts. Embodiments of the subject invention can have a diameter less than 15 cm. Embodiments can have one or more smooth (continuous curvature) surface and can be operated using electromagnetic and electrohydrodynamic principles. The wingless design of specific embodiments can allow operation with no rotating or moving components. Additional embodiments can allow active response to the surrounding flow conditions. The issue of low lift to drag ratio and degradation of airfoil efficiency due to the inability of laminar boundary layers attachment can also be significantly reduced, or eliminated. The electromagnetic force can be generated by applying a pulsed (alternating/rf) voltage between a set of grounded and powered electrodes separated by a polymer insulator, dielectric, or other material with insulating properties. | 04-29-2010 |
| 20100099815 | COUPLED CHARGE TRANSFER NANOTUBE DOPANTS - Stable charge-transfer doping of carbon nanotubes is achieved using a dopant containing polymer (DCP) wherein the DCP has a multiplicity of dopant moieties that are capable of donating electrons to or accepting electrons from the nanotubes linked to a polymer. The DCP has a sufficient number of dopant moieties connected to the polymer such that when charge transfer equilibrium between a particular dopant moiety and the nanotubes is in a dissociated, or dedoped state, the dopant moiety remains tethered by a linking moiety to the polymer and remains in the vicinity of the nanotubes as the polymer remains bound to the tube by at least one bound dopant of the DCP. The linking groups are selected to permit the presentation of the dopant moieties to the nanotubes in a manner that is unencumbered by the polymer backbone and can undergo charge transfer doping. | 04-22-2010 |
| 20100094016 | Thiazoline acid derivatives - The present invention relates to novel thiazoline acids and derivatives thereof useful as chelators of trivalent metals in therapeutic applications. For example, the thiazoline acid derivatives are useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals. | 04-15-2010 |
| 20100093812 | DESFERRITHIOCIN POLYETHER ANALOGUES - A relatively non-toxic desazadesferrithiocin analog having the formula (I): wherein: R | 04-15-2010 |
| 20100076726 | Sensor Registration by Global Optimization Procedures - Disclosed are method and apparatus for registering multiple sensors collecting data from multiple objects. Sensor registration is decomposed into a two-step procedure. The first step corrects systematic errors. The second step assigns objects measured by one sensor to objects measured by a second sensor. Systematic errors are corrected by generating the global minimum of a systematic error function. One embodiment for generating the global minimum uses a Continuous Greedy Randomized Adaptive Search Procedure. | 03-25-2010 |
| 20100076018 | Compounds and Methods for Treatment of Alpha-1 Antitrypsin Deficiency - The invention features compositions and methods that are useful for treating or preventing AAT deficiency and associated conditions. In addition, the invention provides methods for identifying compounds useful for treatment of AAT deficiency and associated conditions. | 03-25-2010 |
| 20100069467 | DOUBLE-STRANDED/SELF-COMPLEMENTARY VECTORS WITH A TRUNCATED CBA PROMOTER AND METHODS OF GENE DELIVERY - The present inventors concerns vectors carrying a truncated chimeric CMV-chicken β-actin (smCBA) promoter in which the hybrid chicken β-actin/rabbit β-globin intron is greatly shortened, and their use to deliver to an operatively linked polynucleotide to host cells in vitro or in vivo, resulting in expression of the polynucleotide in the host cells. In one embodiment, the vector carrying the smCBA promoter is administered to the eye. In another embodiment, the vector carrying the smCBA promoter is a self-complementary adeno-associated virus (AAV). The AAV vector may be of any serotype (e.g., type 1, type 2, type 3, type 4, type 5, type 6, type 7, type 8, type 9, type 10). In another embodiment, a self-complementary vector carrying the smCBA promoter is administered to the eye. Another aspect of the invention concerns host cells carrying a vector of the invention. Another aspect of the invention concerns pharmaceutical composition comprising the vectors or host cells of the invention, and a pharmaceutically acceptable carrier. | 03-18-2010 |
| 20100066370 | Method and Apparatus for Tuning and Matching MRI/NMR Probe - A method and apparatus for tuning the frequency and matching the impedance of an RF coil, or probe, used for nuclear magnetic resonance (NMR)/magnetic resonance imaging (MRI) are provided. In NMR/MRI, the RF coils used to acquire the data are tuned and impedance matched for enhanced performance. An embodiment of the subject invention allows for enhanced frequency and impedance adjustments to be made remotely when, for example, space for accessing the mechanical matching components is limited or not available. Applications in which embodiments of the invention can be beneficial include, but are not limited to, medical systems, very high field research magnets and research or commercial MRI/NMR systems. | 03-18-2010 |
| 20100066349 | Method and Apparatus of Load Detection for a Planar Wireless Power System - Embodiments of the subject invention relate to a method and apparatus for determining information regarding a load in a planar wireless power transfer system by extracting system operating parameters from one or more test points in the transmitter circuit. As shown in FIG. | 03-18-2010 |
| 20100063498 | Methods and Devices for Differentiating Between Tissue Types - The subject invention utilizes the characteristics of in vivo tissue impedances to provide an embodiment of a retinal rake capable of providing a visible and/or preferably an audible signal to a surgeon that more clearly indicates which type of tissue(s) is in contact with the retinal rake. A preferred embodiment comprises a handheld, battery operated retinal rake having two electrodes, wherein at least one electrode is the modified retinal rake. Upon contact with different optical tissues, e.g., epiretinal membranes, retinal tissue, vitreous humor, etc., the electrodes detect varying impedances which are translated by onboard circuitry into various signals that indicate what type of tissue, fluid, structure, etc. is in contact with the retinal rake. | 03-11-2010 |
| 20100056951 | SYSTEM AND METHODS OF SUBJECT CLASSIFICATION BASED ON ASSESSED HEARING CAPABILITIES - A method of assessing hearing characteristics of a subject is provided. The method includes determining a hearing capability of the subject based on responses of the subject to a series of sounds presented to the subject. Each sound corresponds to a presence, absence or irrelevance of a predetermined plurality of features. The method further includes assigning the subject to one of a predetermined plurality of classes based upon the responses of the subject, each of the plurality of classes being derived from hearing tests performed on a plurality of other subjects. | 03-04-2010 |
