| UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK Patent applications |
| Patent application number | Title | Published |
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| 20120114003 | LASER DEVICE, A LIGHT SIGNAL GENERATION DEVICE, AND AN OPTICAL RESONATOR AND A METHOD FOR PRODUCING LIGHT - A laser device includes a ridge waveguide having an active layer between upper and lower cladding layers. A ridge formed in the upper cladding layer defines the width of a light guiding region in the active layer, and is formed so that a portion of the light guiding region extends into the ridge. A plurality of reflecting slots extend across and into the ridge to a depth sufficient to extend into the extending portion in order that the reflectivity of each slot is on the order of 2%. The slots intersect more than 20% of the total mode energy in the light guiding region, and this in combination with the gain of the active layer facilitates lasing within the light guiding region independently of the reflectivity of end facets of the waveguide. The laser device is particularly suitable for integrally forming with other optical components on a single semiconductor chip. | 05-10-2012 |
| 20110269671 | NISIN DERIVATIVES AND THE USE THEREOF - The present invention relates to a nisin derivative comprising amino acid substitutions in the peptide sequence encoding the hinge region of the protein, wherein the derivative exhibits an increased anti-microbial activity. | 11-03-2011 |
| 20110236986 | SENSOR MATERIAL AND USES THEREOF TO SIMULTANEOUSLY SENSE TWO ANALYTES - A sensor material of the type comprising a long-decay photoluminescent, protonable dye embedded in a suitable polymeric matrix, is used for generating a specific optical response to two different analytes present in a sample, thus allowing selective determination of the two analytes in the sample. Also described is a method for the simultaneous sensing of a first and second analyte in a sample. The method comprises the steps of irradiating a sensor material of the type comprising a long-decay photoluminescent protonable dye embedded in a suitable polymeric matrix with light of one or two wavelengths, determining photoluminescence intensity and lifetime signals originating from the sensor, and correlating the photoluminescence intensity signal with a concentration of the first analyte and the photoluminescence lifetime signal(s) with the concentration of the second analyte. | 09-29-2011 |
| 20110200569 | INCREASING THE SHELF LIFE OF BAKERY AND PATISSERIE PRODUCTS BY USING THE ANTIFUNGAL LACTOBACILLUS AMYLOVORUS DSM 19280 - The current inventions relates to a strain of | 08-18-2011 |
| 20110136898 | TREATMENT OF RETINAL DEGENERATION - The use of a compound of general formula (I): or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment or prevention of a disease or condition characterised by apoptosis or degeneration of mammalian cells, wherein: R1 is a alkoxy, alkyl, ether or ester group; R2 is H or has the formula wherein Y is linear or branched, saturated or unsaturated, aliphatic group with from 2 to 23 carbon atoms, or a cyclic group, and which can contain substituents selected from the group consisting of hydroxyl, alkoxy, amino, carboxyl, cyano, nitro, alkylsuphonyl or halogen atoms, X is O or S; and R3 is any substituent. | 06-09-2011 |
| 20110136163 | Method of Toxicological Assessment - A method of assessing toxicity of a candidate agent to a sample of cells comprises the steps of providing a sample of cells, exposing the cells to the candidate agent for a suitable period of time, assaying the cells to measure data for at least one parameter of cellular function; and correlating the measured data of the at least one parameter of cellular function with toxicity, wherein the step of exposing the cells to the candidate agent is carried out in the presence of a reagent capable of facilitating transport of the candidate agent into the cell. The transport reagent may be an endocytosis, pinocytosis inducing agent, a peptide, or a liposome. The at least one parameter of cellular function may be selected from the group consisting of: cell viability; proliferation rate; membrane integrity; and a metabolic parameter. Also described is a method of generating a toxicity signature for a candidate agent comprising the step of carrying out the method of the invention for a plurality of cellular function parameters, and compiling the measured data for each of the cellular function parameters to provide a toxicity signature. | 06-09-2011 |
| 20110110853 | PRIMITIVE VASCULAR PROGENITOR CELLS AND USES THEREOF - Described herein are isolated mammalian cells (progenitor cell biomarkers), referred to as primitive vascular progenitor cells (PVPC), which are present in and isolated from blood (e.g., peripheral blood) and useful as biomarkers of vascular remodeling in mammals (e.g., humans, rodents). | 05-12-2011 |
| 20110019823 | OPTICAL COMMUNICATION SYSTEM AND METHOD FOR SECURE DATA COMMUNICATION USING QUANTUM KEY DISTRIBUTION - The invention provides time-synchronised transmission of data on the (polarisation or phase-modulated) QKD channel and the (on-off modulated) conventional channel such that a QKD bit is only transmitted when a zero, or sequence of zeros, is transmitted on the conventional channel. Also, there is co-directional propagation of the QKD and conventional channel. Further, there is dispersion management through wavelength selection or control of fibre properties or other means such that the “walk-off in time of the QKD pulses and the Raman pulses generated by the ones on the conventional channel is less than or of the order of one bit period. The latter can be achieved, for example, by placing the conventional and QKD channel wavelengths close to the point where the group velocity-induced time delay for optical pulses propagating in the fibre reaches a minimum. This dispersion minimum occurs at a wavelength of 1.3 microns in standard fibre. The invention discloses a receiver embodiment to implement the invention. | 01-27-2011 |
| 20110014303 | METHOD FOR THE TREATMENT OF CANCER - The invention is based on the surprising finding that treatment with a chemotherapeutic agent such as 5-fluorouracil (5-FU) and an autophagy inducer effectively inhibit the continued growth of, and prevent the recovery following drug withdrawal, of cancer cells. In vivo, drug resistance from a failure to adequately engage in apoptotic programmed cell death leads to a recurrence of cancer and tumours can remain dormant for periods of time before re-emerging as drug resistant metastases. It has been hypothesised that autophagy (Type II cell death) may help cancer cells survive in response to growth limiting conditions, such as nutrient depletion, hypoxia, absence of growth factor, or presence of cytotoxic drug. LiCl is a known autophagy inducer and accelerates cell survival to autophagic programmed cell death. | 01-20-2011 |
| 20100302933 | Robust Routing of Data in Wireless Networks - A wireless network ( | 12-02-2010 |
| 20100290495 | LASER DEVICE, A LIGHT SIGNAL GENERATING DEVICE, AND AN OPTICAL RESONATOR AND A METHOD FOR PRODUCING LIGHT - A laser device ( | 11-18-2010 |
| 20100284979 | Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria - The current invention provides use of a CLA-producing bacterium for the in vivo conversion in the gut of polyunsaturated fatty acids to CLA. The CLA-producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria. | 11-11-2010 |
| 20080311080 | BIFIDOBACTERIUM IN THE TREATMENT OF INFLAMMATORY DISEASE - A strain of | 12-18-2008 |
