| UNIVERSITEIT GENT Patent applications |
| Patent application number | Title | Published |
| 20120097547 | Method for Copper Electrodeposition - The present invention is related to a method for electroplating a copper deposit onto a substrate, wherein the method comprises the steps of: a) immersing the substrate into an electroplating bath having a copper ion concentration comprised between 0.5 mmol·l | 04-26-2012 |
| 20120093456 | Coupling Methods and Systems Using a Taper - Disclosed are optical devices for coupling radiation between an optical waveguide and an external medium. In one embodiment, an optical device is disclosed comprising a semiconductor die comprising an integrated optical waveguide core and an overlying optical waveguide comprising a waveguide taper and a waveguide facet. The overlying optical waveguide at least partially overlies the integrated optical waveguide core, and the waveguide facet is between about 1 μm and 200 μm from an edge of the semiconductor die. In another embodiment, a method is disclosed comprising providing a substrate comprising an integrated semiconductor waveguide and forming on the substrate an overlying waveguide comprising a waveguide taper and a waveguide facet. The overlying waveguide at least partially overlies the integrated semiconductor waveguide. The method further includes cutting the substrate about 1 μm and 200 μm from the waveguide facet. | 04-19-2012 |
| 20120064836 | Amplifier Circuit for a Ranging Transceiver - An amplifier circuit is disclosed. In one embodiment, the amplifier circuit includes an input configured to receive an input signal. The amplifier circuit further includes an amplifier connected to the input that is configured to receive the input signal and generate a modulated input signal based on the input signal and one of a first amplification level and a second amplification level. The amplifier comprises a first transistor configured to receive the input signal and a second transistor connected in cascode with the first transistor. The amplifier circuit further includes a switching component configured to switch the amplifier between the first amplification level and the second amplification level. The amplifier circuit still further includes an output connected to the amplifier and configured to output the modulated input signal. | 03-15-2012 |
| 20120064180 | USE OF NO AND NO DONORS FOR TERMINATING DORMANCY IN INVERTEBRATES - The present invention relates to a method for terminating dormancy in an invertebrate, wherein said invertebrate is brought in contact with nitric oxide and/or a nitric oxide donor. The method can be used in pest management of unfavourable species, in eliminating dormant stages of aquatic invertebrates in ballast water in promoting termination of dormancy in beneficial species and/or in stimulating production of live food in aquacultures. | 03-15-2012 |
| 20120062978 | METHOD FOR OPERATING A MICROMIRROR DEVICE WITH ELECTROMECHANICAL PULSE WIDTH MODULATION - A method of operating by pulse width modulation a micromirror device is disclosed. In one aspect, the method includes providing a micromirror device having a micromirror element electrostatically deflectable around a rotation axis between a first and second position. The micromirror element is controllable by applying voltage signals to a first and second electrode on one side of the rotation axis and a third and fourth electrode on the other side. The method includes associating an intermediate value of intensity to the micromirror element during a time frame, the intensity being between a first value corresponding to the first position and a second value corresponding to the second position. The method includes switching the micromirror element between the first and second position. The intermediate value corresponds to the ratio of periods in the time frame in which the micromirror element is in the first or second position. | 03-15-2012 |
| 20120058551 | TECHNOLOGY AND METHOD TO STUDY MICROBIAL GROWTH AND ADHESION TO HOST-RELATED SURFACES AND THE HOST-MICROBIOTA INTERACTIONS - The present invention relates to in vitro adhesion modules that allow growth, stabilization and study of microbial communities that adhere to and colonize host-related surfaces, that mimic transport of chemical compounds across epithelial surfaces and simulate host-microorganism interactions and adaptation. It includes the provision of micromolar amounts of oxygen via the basal side of a mucus layer towards the adhered microorganisms thus establishing the microaerophilic conditions prevailing at the base of a biofilm. It can also include cells, simulating the host, in a chamber on the basal side of a functional layer comprising said mucus layer. The adhesion module of the present invention can be placed between the different compartments of the SHIME—the Simulator of the Human Intestinal Microbial Ecosystem. An extension of the SHIME is made where the duodenum, jejunum and ileum are separately mimicked. | 03-08-2012 |
| 20120029174 | METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step. | 02-02-2012 |
| 20120023624 | MEANS AND METHODS FOR MEDIATING PROTEIN INTERFERENCE - The present invention belongs to the field of functional proteomics and more particularly to the field of protein aggregation. The invention discloses a method for interfering with the function of a target protein and uses a non-naturally, user-designed molecule, designated as interferor, that has a specificity for a target protein and which induces aggregation upon contact with said target protein. The present invention also discloses such interferor molecules and their use in agrobiotech applications. | 01-26-2012 |
| 20120014749 | REMEDIATION OF POLLUTED MATERIALS OR SITES - The invention relates to a method and a system for controlling a remediation of a site polluted by contaminants, the method comprising the steps of determining a concentration gradient of gaseous emissions exhausting from the polluted site taking into account the measured indications measured at a plurality of spatially distinct positions, and controlling a remediation technique taking into account the concentration gradient. Automatic feedback for controlling the underlying remediation technique is thus enabled taking into account the concentration gradient. | 01-19-2012 |
| 20110311227 | Systems and Methods for Transferring Single-Ended Burst Signal Onto Differential Lines, Especially for Use in Burst-Mode Receiver - Systems and methods for transferring incoming single-ended burst signals of which at least one characteristic varies widely from burst to burst onto a pair of differential lines. The systems comprise an input for receiving an incoming burst signal, a signal adaptation block for adapting said widely varying characteristic and a single-ended-to-differential converter. In a first aspect a reset signal for resetting a settings determination block, which controls the signal adaptation block, is sent backwards over the differential lines, preferably using a common-mode signal. In a second aspect, a status freezing mechanism is employed for freezing the settings of the settings determination block after the end of the preamble of an incoming burst. | 12-22-2011 |
| 20110300562 | GDF15 AS A DIFFERENTIAL MARKER FOR SPONDYLOARTHROPATHY - In vitro methods for differential diagnosis of spondyloarthropathy are disclosed which involve determining the levels of GDF15 in biological samples. | 12-08-2011 |
| 20110300548 | GDF15 AS MOLECULAR TOOL TO MONITOR AND ENHANCE PHENOTYPIC STABILITY OF ARTICULAR CHONDROCYTES - The present invention relates to GDF15 as a molecular marker in in vitro assays determining phenotypic stability of articular chondrocytes and predicting the outcome of chondrocyte transplantation. | 12-08-2011 |
| 20110294864 | AQUEOUS COACERVATE COMPOSITIONS SUITABLE FOR MAKING POWDERS AND WATER-SOLUBLE FORMULATIONS OF BIOLOGICALLY-ACTIVE AGENTS - Aqueous gel-free two-phase coacervate compositions including a coacervate phase and an equilibrium water phase, comprising a mixture of:
| 12-01-2011 |
| 20110278441 | Transparent Photonic Integrated Circuit - Photonic structures and methods of operating the photonic structures are disclosed. In one embodiment, the photonic structure includes a detector configured to detect radiation of a first wavelength range. The radiation of the first wavelength range is received from an external radiation guide, and the detector is substantially transparent to radiation of a second wavelength range that differs from the first wavelength range. The photonic structure further includes a coupling structure configured to free space couple out of the photonic structure radiation of the second wavelength range. The photonic structure further includes a guiding structure configured to optically guide the radiation of the second wavelength range through the detector. | 11-17-2011 |
| 20110222856 | All-Optical 2R Regeneration - A method is provided for all-optical regeneration of intensity modulated optical signals. A DFB laser diode is selected such that it has a gain bandwidth comprising the signal wavelength, the signal wavelength being outside the stopband of the DFB laser diode. Furthermore, the DFB laser diode is selected such that it can have a bistable amplification characteristic for the signal wavelength showing a hysteresis with an ascending branch and a descending branch, the ascending branch located at a higher input power level than the descending branch. The DFB laser diode is driven such that it operates in the bistable amplification regime, the descending branch of the hysteresis curve located at an input power level above the lower power level of the optical signal pulses and the ascending branch of the hysteresis curve located at an input power level below the upper power level of the optical signal pulses. | 09-15-2011 |
| 20110191913 | CELLS PRODUCING GLYCOPROTEINS HAVING ALTERED GLYCOSYLATION PATTERNS AND METHOD AND USE THEREOF - The present application relates to the field of glyco-engineering, more specifically to eukaryotic cells wherein both an endoglucosaminidase and a glycoprotein are present. These cells can be used to deglycosylate or partly deglycosylate the (exogenous) glycoprotein, in particular without the need for adding an extra enzyme. Methods are also provided for the application of these cells in protein production. According to one specific aspect, the eukaryotic cells and methods are glyco-engineered yeast cells in which additionally at least one exogenous enzyme needed for complex glycosylation is present, e.g. allowing easier separation of differentially glycosylated glycoproteins. | 08-04-2011 |
| 20110190273 | METHODS AND COMPOSITIONS IN THE TREATMENT OF CORONAVIRUSES - The invention relates generally to the field of virology, and relates to the identification and characterization of the targets involved in the evasion strategy of viruses and to the use thereof in methods to identify anti-viral compounds. More in particular to identify compounds which are modulators of myosin light chain kinase (MLCK), a target within said entry and immune-evasion strategy. Other aspects of the invention are directed to anti-viral compounds identified using the models and methods of the present invention, as well as to the use thereof in treating viral infections, such as for example caused by the feline infectious peritonitis virus (FIPV), a coronavirus which belongs to an antigenic group which comprises in particular feline enteric coronavirus (FECV), canine coronavirus (CCV), swine transmissible gastroenteritis coronavirus (TGEV), porcine respiratory coronavirus (PRCV) and human coronavirus (HCV), and which induces, in a host-dependent manner, a range of symptoms which range from mild enteritis to the severe debilitating disease, and, in some cases, up to death. In a particular aspect the present invention provides the use of MLCK inhibitors for the treatment of feline infectious peritonitis (FIP). | 08-04-2011 |
| 20110184049 | LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF - The present invention relates to nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy. | 07-28-2011 |
| 20110162109 | Plants Having Modified Growth Characteristics and a Method for Making the Same - The present invention relates generally to the field of molecular biology and concerns a method for improving various economically important growth characteristics in plants. More specifically, the present invention concerns inter alia a method for modifying growth characteristics in plants by modulating expression in a plant of a nucleic acid encoding a HUB1 (Histone Monoubiquitination 1) polypeptide or encoding another protein useful in the methods of the present invention. The modified growth characteristics comprise a modification of light regulated phenotypes, such as modified circadian clock and/or circadian clock responses, or modified plant architecture. | 06-30-2011 |
| 20110150940 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 06-23-2011 |
| 20110136240 | DIAGNOSTIC TEST FOR THE DETECTION OF EARLY STAGE LIVER CANCER - The invention provides methods and kits to detect early stage hepatocellular carcinoma or a change in the gradation of hepatocellular carcinoma in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. | 06-09-2011 |
| 20110129525 | MUCOSAL MEMBRANE RECEPTOR AND USES THEREOF - The invention is based on the identification of aminopeptidase N (APN) as the receptor for F4 fimbriae of enterotoxigenic | 06-02-2011 |
| 20110116735 | Retro-Reflective Structures - A photonic integrated circuit ( | 05-19-2011 |
| 20110108646 | PROCESS AND APPARATUS FOR CONTINUOUS WET GRANULATION OF POWDER MATERIAL - An apparatus for wet granulating a powder material comprises:—a barrel having a granulation chamber and being provided with a first inlet ( | 05-12-2011 |
| 20110104183 | USE OF SIP1 AS DETERMINANT OF BREAST CANCER STEMNESS - The present invention relates to the diagnosis and treatment of cancer. More specifically, it relates to the use of SIP1 nucleic acid and/or protein for the detection of breast cancer stem cells, and the repression of the gene and/or the inactivation of the protein to repress the differentiation of cells into cancer cells and to inhibit metastasis of breast cancer tumors. | 05-05-2011 |
| 20110103743 | METHOD AND SYSTEM FOR COUPLING RADIATION - The present invention relates to a coupler ( | 05-05-2011 |
| 20110100816 | BLOOD SERUM MARKER FOR DETECTION AND DIAGNOSIS OF ALZHEIMER'S DISEASE - The present invention relates to a blood marker for early detection and diagnosis of Alzheimer's disease. More specifically, it relates to an analysis of the protein glycan profile in the blood, and the identification of specific peak ratio's when compared to healthy aged matched subjects that are typical for Alzheimer's dementia. | 05-05-2011 |
| 20110092374 | METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step. | 04-21-2011 |
| 20110082046 | METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE - The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step, wherein the identification purpose step is a detection step for the detection of an encoded microcarrier having an anisotropy in its shape. The invention further relates to an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscoper and means for the positioning and orientation of the microcarriers. | 04-07-2011 |
| 20110078825 | Modulation of plant cell number - The invention relates to the use of the ANG4 gene, or a variant thereof, to modulate the cell number of a plant organ. The modulation can be used to increase the plant biomass, or to adapt the plant architecture. | 03-31-2011 |
| 20110075970 | Integrated Photonics Device - The present invention relates to an integrated photonic device ( | 03-31-2011 |
| 20110075446 | Circuit for Converting a Pulsed Input Voltage to a DC Voltage - The present disclosure presents a circuit for converting a pulsed input voltage to a DC output voltage. The circuit comprises input nodes for receiving the pulsed input voltage and output nodes for outputting the DC output voltage. The circuit further comprises a first transistor and a second transistor connected between the input and the output nodes in a synchronous rectifier configuration. The first and second transistors each have a gate connected to a driving circuit configured for alternately charging the gates of the transistors whereby the driving circuit comprises an auxiliary circuit not directly connected to the input nodes and configured for providing a predetermined auxiliary supply voltage to the gates. In an embodiment, the auxiliary circuit comprises a buck DC-DC converter of which an input node is connected to the output nodes and of which an output node is connected to the gates. | 03-31-2011 |
| 20110069952 | Circuit for End-of-Burst Detection - A circuit for end-of-burst detection in a portion of a received bit stream is disclosed. The circuit comprises:
| 03-24-2011 |
| 20110065638 | NOVEL CRUSTACEAN ANDROGENIC GLAND HORMONE - The present invention relates to a novel crustacean androgenic gland hormone. More specifically, the invention relates to an androgenic gland hormone derived from | 03-17-2011 |
| 20110038887 | Novel Vaccine Against Trypanosoma Cruzi Infection - The present invention relates to a vaccine against | 02-17-2011 |
| 20110037179 | SEMICONDUCTOR PACKAGE - A semiconductor package is disclosed. In one aspect, the package includes a base frame and a wiring substrate mounted on the base frame. The base frame has two pieces made of a material with respectively a first and a second coefficient of thermal expansion and connected to each other via resilient connecting structures. The wiring substrate has electric wiring tracks providing the electric connection between first and second bond pads, provided for being electrically connected to bond pads on respectively a die and a printed wiring board. The electrical wiring tracks have flexible parts provided to expand and contract along with the resilient connecting structures. | 02-17-2011 |
| 20110027377 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from above about 20% to 50% by weight of the composition, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 85% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharma-ceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 02-03-2011 |
| 20110026921 | Systems and Methods for Transferring Single-Ended Burst Signal Onto Differential Lines, Especially for Use in Burst-Mode Receiver - Systems and methods for transferring incoming single-ended burst signals of which at least one characteristic varies widely from burst to burst onto a pair of differential lines. The systems comprise an input for receiving an incoming burst signal, a signal adaptation block for adapting said widely varying characteristic and a single-ended-to-differential converter. In a first aspect a reset signal for resetting a settings determination block, which controls the signal adaptation block, is sent backwards over the differential lines, preferably using a common-mode signal. In a second aspect, a status freezing mechanism is employed for freezing the settings of the settings determination block after the end of the preamble of an incoming burst. | 02-03-2011 |
| 20110021378 | NUCLEIC ACIDS OF PICHIA PASTORIS AND USE THEREOF FOR RECOMBINANT PRODUCTION OF PROTEINS - The present invention provides the genome sequence of | 01-27-2011 |
| 20110020406 | VIRAL INACTIVATION PROCESS - The invention relates generally to the field of virology. More particularly, the present invention relates to methods for determining the effect of a viral inactivation procedure on the antigenicity of the inactivated virus. In particular for a virus that is a member of the family Arteriviridae or Coronaviridae or Asfarviridae, in particular for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The invention further provides methods to determine the antigenicity of an inactivated virus as well as methods to screen for anti-viral compounds using any one of the aforementioned methods Methods of using the inactivated and immunogenic virus thus obtained, in particular in the manufacture of a vaccine are also provided by the present invention. | 01-27-2011 |
| 20110013874 | Method for Effective Refractive Index Trimming of Optical Waveguiding Structures and Optical Waveguiding Structures - A method for trimming an effective refractive index of optical waveguiding structures made for example in a high refractive index contrast material system. By compaction of cladding material in a compaction area next to patterns or ridges that are formed in the core material for realizing an optical waveguiding structure, the effective index of refraction of the optical waveguiding structure can be trimmed. Thus, the operating wavelength of an optical component comprising such an optical waveguiding structure can be trimmed. An optical waveguide structure thus obtained is also disclosed. | 01-20-2011 |
| 20110008454 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from 0.5% to 20% by weight of the composition, and excipients, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 80% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharmaceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 01-13-2011 |
| 20100330036 | MARKERS OF MATRIX GENE EXPRESSION AND CELLULAR DIFFERENTIATION IN CHONDROCYTES - The invention relates generally to the field of tissue engineering. More particularly, the present invention relates to methods for identifying a population of cells suitable for the repair of connective tissue, including cartilage. The invention further provides methods and compositions related to the generation of a population of cells suitable for the repair of cartilage, in particular in the repair of cartilage degeneration associated with osteoarthritis. Methods of using said cells thus identified or thus generated, in methods to extend the period of cell manipulation, i.e. to increase the yield of cells suitable in the aforementioned methods, are also provided by the present invention. | 12-30-2010 |
| 20100322555 | Grating Structures for Simultaneous Coupling to TE and TM Waveguide Modes - Disclosed are an integrated optical coupler, and a method of optically coupling light, between an optical element and at least one integrated optical waveguide. The optical coupler includes a grating structure and is adapted for coupling light to waveguide modes with different polarization with low polarization dependent loss. For example, polarization dependent loss may be smaller than 0.5 dB. The waveguide modes may include a Transverse Electric (TE) waveguide mode and a Transverse Magnetic (TM) waveguide mode. The optical coupler may further include a two-dimensional grating structure adapted for providing polarization splitting for a first optical signal of a first predetermined wavelength and for coupling both polarizations forward or backward. | 12-23-2010 |
| 20100321072 | Device and Method for Signal Detection in a TDMA Network - The present invention is related to a circuit ( | 12-23-2010 |
| 20100307241 | COMBINED MEMS ACCELEROMETER AND GYROSCOPE - A MEMS structure for a combined gyroscope and accelerometer unit ( | 12-09-2010 |
| 20100278484 | Waveguide Coupling Probe and Methods for Manufacturing Same - A waveguide coupling probe ( | 11-04-2010 |
| 20100234482 | FUNCTIONALISED POLYURETHANES - The present invention relates to a method for producing an isocyanate-based polymeric material by polymerizing a reaction mixture which comprises different reaction components, including at least one polyisocyanate component and at least one component which is reactive towards said polyisocyanate component. The reaction components comprise at least one anchor component which has at least one anchor group which enables to bond a functional component covalently to the polymeric material. The anchor group is a reactive unsaturated group which does not react during the polymerisation process so that the polymerisation process is not interfered. The anchor group is selected to that it can bind the functional component by a click chemistry reaction to the polymeric material. It is more particularly selected so that it can participate in a catalysed Huisgen 1,3-dipolar cycloaddition reaction or in a Diels-Alder cycloaddition reaction The invention also relates to the obtained isocyanate-based polymeric material, to the use thereof to produce a functionalised polymeric material and to this functionalised polymeric material. | 09-16-2010 |
| 20100183750 | FORTIFICATION OF PLANTS WITH FOLATES BY METABOLIC ENGINEERING - The invention relates to a transgenic plant overexpressing a polynucleotide encoding a plant GTP cyclohydrolase I (GTPCHI) enzyme. The present invention also relates to a product comprising the transgenic plant of the invention or a harvestable part, plant organ, plant tissue, plant cell, seed, or a propagule of said plant. The present invention further elucidate the use of the plant of the invention to cross breed with other plants, as biofortification to enrich the quality of the food intake of an animal or human subject, for the manufacture of a medicament to prevent folate insufficiency, or, for the treatment of folate insufficiency or diseases or disorders resulting from said insufficiency in an animal or human subject. | 07-22-2010 |
| 20100160455 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS - Novel vitamin D analogues are useful for making pharmaceutical compositions for the prevention or treatment of bone disorders such as osteoporosis | 06-24-2010 |
| 20100152253 | NON-STEROIDAL BRASSINOSTEROID MIMETIC - The present invention relates to non-steroidal mimetics of brassinosteroids. More specifically, it relates to non-steroidal monocyclic compounds, capable of rescuing the brassinosteroid receptor null mutation bri1-116. Preferably, said compounds are low molecular weight, monocyclic halogenated compound. | 06-17-2010 |
| 20100119229 | METHOD AND SYSTEM FOR MULTIPLEXER WAVEGUIDE COUPLING - An optical device for optically multiplexing or demultiplexing light of different predetermined wavelengths is provided, the optical device comprising at least one first waveguide ( | 05-13-2010 |
| 20100093807 | SUBSTITUTED 7-AZABICYCLO[2.2.1]HEPTYL DERIVATIVES USEFUL FOR MAKING PHARMACEUTICAL COMPOSITIONS - This invention provides 1-substituted-7-azabicyclo[2.2.1]heptyl derivatives, intermediates and methods for producing them, which are therapeutic agents useful for the prevention and treatment of central nervous system disorders and diseases mediated by a Nicotinic Acetylcholine Receptor such as Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, pain, nicotine addiction and dementia. | 04-15-2010 |
| 20090326078 | PROCESS FOR PREPARING A SOLID DOSAGE FORM - This invention provides a process for preparing a solid dosage form, comprising:—preparing an aqueous slurry, solution or suspension of (a) a powder material, and (b) a mixture of one or more polyols and one or more maltodextrins, and—spray drying the resultant aqueous slurry, solution or suspension, thereby obtaining particles which are directly compressible into a solid dosage form being able to disintegrate in an aqueous medium within no more than 15 minutes. | 12-31-2009 |
| 20090317639 | METHOD FOR MANUFACTURING A STRETCHABLE ELECTRONIC DEVICE - A method for manufacturing a stretchable electronic device is disclosed. In one aspect, the device comprises at least one electrically conductive channel connecting at least two components of the device. The method comprises forming the channel by laser-cutting a flexible substrate into a predetermined geometric shape. | 12-24-2009 |
| 20090298066 | Sex-Specific Marker for Shrimps and Prawns - The present invention relates to a sex-specific marker for shrimps and prawns. More specifically, it relates to a sex-specific PCR-based molecular marker, derived from | 12-03-2009 |
| 20090285856 | HELICOBACTER SPECIES AND CULTIVATION THEREOF - The present invention relates to the isolation and cultivation of “Candidatus | 11-19-2009 |
| 20090275616 | STRAIGHTFORWARD ENTRY TO 7-AZABICYCLO[2.2.1]HEPTANE-1-CARBONITRILES AND SUBSEQUENT SYNTHESIS OF EPIBATIDINE ANALOGUES - The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction. | 11-05-2009 |
| 20090263863 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST - The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided. | 10-22-2009 |
| 20090239900 | QUININE AND QUINIDINE SALTS, METHODS FOR MAKING THEM, AND PHARMACEUTICAL FORMULATIONS COMPRISING THEM - The present invention provides a combination of:
| 09-24-2009 |
| 20090222952 | Plants Having Improved Growth Characteristics And A Method For Making The Same - The present invention concerns a method for increasing plant yield and/or increased stress resistance by decreasing the level of activity of a DEL1 polypeptide. One such method comprises introducing into a plant a nucleic acid comprising a variant DEL1 nucleic acid. Another method comprises downregulating expression of a DEL1 gene. The invention also relates to transgenic plants having introduced therein a variant DEL1 nucleic acid thereof, which plants have increased yield and/or increased stress resistance relative to control plants. The present invention also concerns a novel DEL1 protein and its encoding sequence, and constructs useful in the methods of the invention. | 09-03-2009 |
| 20090151021 | Novel Stress-Related MicroRNA Molecules and Uses Thereof - Naturally occurring and synthetic novel stress-related miRNAs are provided which can be used to modify the stress tolerance of plants. | 06-11-2009 |
| 20090107704 | COMPOSITE SUBSTRATE - A composite substrate is disclosed. In one aspect, the substrate has a stretchable and/or flexible material. The substrate may further have patterned features embedded in the stretchable and/or flexible material. The patterned features have one or more patterned conducting layers. | 04-30-2009 |
| 20090100545 | Means and Methods to Modulate Flavonoid Biosynthesis in Plants and Plant Cells - The present invention provides a method for increasing the flavonoid content of plants and plant cells wherein said method comprises increasing the activity of genes implicated in the flavonoid biosynthesis pathway. The invention further relates to recombinant plant and plant cells obtainable by the process of the invention and to flavonoids made there from. | 04-16-2009 |
| 20090087882 | Protein secretion in eukaryotic cells - The invention relates to the use of a glucosidase II mutation to increase protein secretion in yeast cells. The invention relates further to the use of yeast cells, comprising a mutant glucosidase II gene, possibly in combination with the expression of a recombinant α-1,2-mannosidase gene and/or a recombinant N-acetylglucosaminyl-transferase gene, as a host for protein secretion. | 04-02-2009 |
| 20090041852 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 02-12-2009 |
| 20090029999 | Synephrine derivatives useful as anti-inflammatory agents - This invention provides compounds having the structural formula: | 01-29-2009 |
| 20090028892 | Ostertagia Vaccine - The present invention relates to nucleic acid sequences encoding | 01-29-2009 |
| 20080312190 | Organophosphoric Derivatives Useful as Anti-Parasitic Agents - The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, C | 12-18-2008 |
| 20080310456 | Communication System over a Power Line Distribution Network - The present disclosure provides a system for receiving signals over a power line distribution. Typically, problems of noise and interference are being solved at the receiver side. Systems of the present disclosure, however, are not limited to the receiver-side solution. Systems according to the present disclosure may also be used at the transmitter side. The receiver comprises a high pass filter, a preselect crossover filter, and an analog front-end receiver architecture. | 12-18-2008 |
| 20080271208 | Modulation of Plant Cell Number - The present invention relates to the use of the ANG4 gene, or a variant thereof, to modulate the cell number of a plant organ. Said modulation can be used to increase the plant biomass, or to adapt the plant architecture. | 10-30-2008 |
| 20080262160 | Monodisperse Polymers Containing (Alkyl)Acrylic Acid Moieties, Precursors and Methods for Making them and their Applications - This invention relates to monodisperse or nearly monodisperse (co)polymers containing acrylic or (α-substituted)acrylic acid moieties, polymeric precursors thereof as well as methods for making them by at least partial hydrolysis of said polymeric precursors. The invention also relates to compositions comprising such (co)polymers optionally in combination with polymer processing additives for use in various fields of technology including imaging applications. | 10-23-2008 |
| 20080254069 | VACCINES FOR IMMUNIZATION AGAINST HELICOBACTER - The invention relates to the immunisation of pigs against | 10-16-2008 |
| 20080220473 | Endo-N-Acetyl-Beta-D-Glucosaminidase Enzymes of Filamentous Fungi - The present invention discloses mannosyl-glycoprotein endo-beta-N-acetylglucosamidase (E.C.3.2.1.96, endo-N-acetyl-beta-D-glucosaminidase acting on the di-N-acetylchitobiosyl part of N-linked glycans) from filamentous fungi such as | 09-11-2008 |