| 20090269793 | Compounds and Kits for the Detection and the Quantification of Cell Apoptosis - The present invention relates a compound of formula (1) wherein: —R1 represents a linear alkyl group of 4 to 20 carbon atoms; —Y represents a linear alkyl group of 1 to 5 carbon atoms or a group of formula —R—O—R′—, —R—CO—R′— or —R—CO—NH—R′—, in which R represents a linear alkyl group of 1 to 3 carbon atoms, R′ represents a linear alkylene group of 0-3 carbon atoms, Y being linked to the bicycle in position 6 or 7; -Z represents a linear alkyl chain of 3 or 4 carbon atoms; -A represents an oxygen atom, a sulphur atom, or a —NH group, or an amminoalkyl group —NR″ in which R″ represents an alkyl group of 1 to 20 carbon atoms; —Ar represents an aromatic cycle or polycycle consisting of 6 to 14 carbon atoms, or an aromatic heterocycle, said heterocycle containing 4, 5 or 6 carbon atoms and at least one heteroatom selected in the group consisting of N, S, and O, or a condensed aromatic heterobicycle, said heterobicycle consisting of 6 to 9 carbon atoms and at least one heteroatom selected in the group consisting of N, S, and O; —R2 and R3, which are identical or different, each representing a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, R2 and R3 optionally forming a 5- to 7-membered ring with the nitrogen atom; —R4, R5 and R6, identical or different, represent an hydrogen, a linear alkyl group or a linear oxyalkyl group of 1 to 4 carbon atoms. | 10-29-2009 |
