| UNIVERSITE DE POITIERS Patent applications |
| Patent application number | Title | Published |
|---|
| 20120122916 | SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES - The invention concerns screening molecules with anti-prion activity. More particularly, it concerns kits for screening molecules with anti-prion activity characterized in that they comprise in combination a [PSI+], phenotype yeast, an antibiogram and an agent for purifying prions at sub-efficient doses, said yeast including the ade1-14 allele of the ADE1 gene and an inactivated ERG6 gene, the screening methods, and a family of molecules with anti-prion activity isolated by the inventive screen. The invention is applicable to anti-prion agents for producing medicines in particular for treating neurodegenerative diseases involving protein aggregates. | 05-17-2012 |
| 20120085683 | METHOD FOR ELECTROSTATICALLY SEPARATING A GRANULE MIXTURE MADE OF DIFFERENT MATERIALS, AND DEVICE FOR IMPLEMENTING SAME - A method and a device for electrostatically separating polyvalent granular insulating materials that have good properties, are energy efficient, and easily adapt to ambient atmospheric conditions and to physiochemical properties of the granules to be separated. The method includes: a) injecting a current of air between two electrodes in a separation chamber defined by walls and having an air inlet and outlet; b) placing the granule mixture, made of different materials, into the air current; c) controlling the air current so that the granules levitate in the air current in a turbulent mode and become electrically charged by contact therebetween and/or by contact with the walls of the separation chamber; d) generating an electric field between two electrodes, substantially perpendicular to the direction of the air current, such that the charged granules in c) move, either in the direction of the electric field if the granules are positively charged or in the opposite direction if the charge thereof is negative; e) adhering the charged granules to the surface of the electrodes; and f) discharging and collecting the granules adhering to each electrode. | 04-12-2012 |
| 20110269795 | USE OF GLUCOSIDASE INHIBITORS FOR THERAPY OF MUCOVISIDOSIS - A method provides for the use of glycosidase inhibitors selected from compounds of general formula (1), wherein R | 11-03-2011 |
| 20110166702 | ELECTRONIC BOARD AND SYSTEM COMPRISING A PLURALITY OF SUCH BOARDS - The invention relates to an electronic board (C) comprising: a microcontroller; a first interface means ( | 07-07-2011 |
| 20110092483 | SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES - A kit and a method for identifying compounds having anti-prion activity are provided. The kit comprises a yeast of phenotype [PSI+]; an antibiogram; and a prion curing agent in a sub-effective dose, wherein the yeast has the adel-14 allele of the ADE1 gene and an inactivated ERG6 gene. Compounds and pharmaceutical compositions having anti-prion activity are also provided, which are useful for treating various neurodegenerative diseases, including polyglutamines expansion associated diseases; Huntington's disease; Kennedy disease; amyotrophic lateral sclerosis; cerebellous autosomic ataxies; dentalorubral-pallidoluysian atrophy; and spino-bulbar amyotrophy. | 04-21-2011 |
| 20110064559 | METHOD AND APPARATUS FOR CONTROLLING TONAL NOISE FROM SUBSONIC FANS - A method and apparatus for reducing a selected tonal noise generated by a fan operating in a non-uniform flow by locating at least one obstruction in the non-uniform flow such that the at least one obstruction generates a noise that is out of phase with the selected tonal noise. The noise generated by the at least one obstruction interferes with the selected tonal noise, thus reducing the selected tonal noise. It is also contemplated to use additional obstructions to reduce other tonal noises generated by the fan. | 03-17-2011 |
| 20110042162 | DEVICE FOR REDUCING NOISE GENERATED BY AN AIRCRAFT JET ENGINE WITH CURVE DUCTS - A jet engine, including a wall surrounding a first gas flow ejected from a downstream end of the wall along a longitudinal axis, a second flow of gas running outside the wall in a direction of ejection of the first gas flow, at least one duct arranged on the periphery of the downstream end of the wall which is desired to eject a gas flow for interacting with one and/or the other gas flow, the at least one duct including a terminal section provided at the free end thereof with an outlet opening through which the fluid is ejected. The terminal section successively includes a first section of straight duct aligned along a median axis and a second duct section forming a bend relative to the straight section, the second portion having a free end provided with the outlet opening and sufficiently close to the median axis of the first section to give the terminal section a reduced restriction in a direction of formation of the bend. | 02-24-2011 |
| 20110030341 | DEVICE WITH SECONDARY JETS REDUCING THE NOISE GENERATED BY AN AIRCRAFT JET ENGINE - An aircraft jet engine including a wall centered about a longitudinal axis and surrounding a stream of gas ejected at a downstream end of the wall in the direction of the axis, primary ducts distributed at the periphery of the downstream end of the wall configured on command each to eject a jet of primary fluid to interact with the ejected stream of gas, the primary ducts of each pair converging towards one another near the downstream end of the wall so that the primary jets ejected form two sides of a triangle that meet at the vertex thereof in a view projected onto a plane perpendicular to a transverse plane, and secondary ducts each associated with each pair of primary ducts and configured on command to eject a jet of secondary fluid directed into the triangle formed by the primary jets. | 02-10-2011 |
| 20100065680 | DEVICE WITH PLANE JETS FOR REDUCING THE NOISE GENERATED BY A JET AIRCRAFT - The invention relates to an aircraft engine having a longitudinal axis (XX′), comprising a wall ( | 03-18-2010 |
| 20100045984 | DEVICE FOR EVALUATING THE STATE OF WETTING OF A SURFACE, EVALUATION METHOD AND ASSOCIATED INDICATION DEVICE | 02-25-2010 |
| 20090300776 | COMPOSITIONS FOR PREVENTING, REDUCING OR TREATING KERATINOCYTE-MEDIATED INFLAMMATION - The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to inhibit a heteromeric receptor comprising OSMRβ as a subunit, for the preparation of a composition for inhibiting the expression of inflammatory factors by the keratinocytes. In particular, the invention concerns the use of antagonists and/or expression inhibitors of OSM, IL-17, TNFα, IL-31, IFN-γ, and/or the OSMRβ subunit, for the preparation of cosmetic or dermatologic compositions, especially for treating inflammatory skin diseases. | 12-03-2009 |
