| UNIVERSITATSKLINIKUM HAMBURG-EPPENDORF Patent applications |
| Patent application number | Title | Published |
| 20100210612 | DETECTION OF ESR1 AMPLIFICATION IN ENDOMETRIUM CANCER AND OVARY CANCER - The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative disease of the endometrium or ovary as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative disease of the endometrium or ovary as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative disease of the endometrium or ovary who is at risk of developing endometrial or ovarian cancer. The invention also provides kits for performing the above methods. | 08-19-2010 |
| 20100184083 | RELEASED CYTOKERATINS AS MARKERS FOR EPITHELIAL CELLS - The present invention is directed to methods of detecting viable epithelial cells in a sample. The method includes isolating the sample comprising cells from a patient and culturing the cells for a time sufficient for an epithelial cell-specific marker to be released from the cells. The marker includes a substantially full-length cytokeratin. The method further includes detecting the released marker. Detection of the marker indicates the presence of disseminated epithelial cells. Methods are also directed to identifying disseminated epithelial tumor cells. | 07-22-2010 |
| 20100167373 | Pouch-Like Construct for Preventing Heart Distension - The invention is directed to a pouch-like construct comprising mammalian tissue which can be used for preventing distension and/or resisting dilation of the heart in a mammal. Preferably, the pouch-like tissue construct has contractile properties. The invention further relates to a method for the preparation of a pouch-like construct comprising mammalian tissue which can be used for the above purposes. | 07-01-2010 |
| 20100136029 | Use of Tri-Substituted Glycerol Compounds for the Treatment of Hematological Malignancies - The present invention relates to the use of a tri-substituted glycerol compound for the manufacture of a medicament for the treatment of hematological malignancies. The invention also refers to a kit-of-parts comprising such a medicament. Finally, the invention also relates to a corresponding method for the treatment of such conditions as well as to an in vitro method for determining the susceptibility of such malignant cells to a medicament as defined in the invention. | 06-03-2010 |
| 20090006043 | Method for the simulation of the haptic of an interaction of a guided object with a virtual three-dimensional object - The object of the instant invention is a method for simulating the haptics of an interaction of an object guided by a user, hereinafter referred to as tool, with a virtual three-dimensional object, in particular the scanning of the surface of the simulated object and/or the penetration of the guided object into the simulated object, under material removal, if applicable. | 01-01-2009 |