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UNIVERSITAT HEIDELBERG

UNIVERSITAT HEIDELBERG Patent applications
Patent application numberTitlePublished
20110118439Three-Dimensional Structure Of The Amyloid Precursor Protein Intracellular Domain (AICD) In Complex With Human FE65-PTB2 - The present invention relates to a three-dimensional structure of the intracellular domain (AICD) of human amyloid precursor protein (APP695) in complex with human Fe65-PTB2 (i.e. a protein-complex comprising the intracellular domain (AICD) of human amyloid precursor protein (APP695) and the human Fe65-PTB2), as well as to methods and uses of said three-dimensional structure for identifying ligands which modify the interaction between the AICD and the Fe65-PTB2. Moreover, the present invention relates to pharmaceutical compositions which contain one or more of such identified ligands for the prevention or treatment of neurodegenerative disorders.05-19-2011
20100315708TOTAL INTERNAL REFLECTION INTERFEROMETER WITH LATERALLY STRUCTURED ILLUMINATION - A total internal reflection microscope for epi-fluorescence illumination observations includes an objective through which an object to be observed is illuminated by an excitation illumination light at an angle to an observation axis of the microscope. The angle is adjustable to be within the range suitable for a total internal reflection observation. The microscope also has a source of collimated excitation light. An interferometer is arranged in the optical path of the collimated excitation light and is configured to produce an interference pattern. A focusing lens system focuses the interference pattern produced by the interferometer into the back focal plane of the objective. The objective and the focusing lens system image the interference pattern produced by the interferometer into the conjugated image plane of the objective, thereby producing excitation illumination light that modulated spatially in intensity in a plane orthogonal to the observation axis of the microscope.12-16-2010
20100172825Molecular Hydrogen Stores and Hydrogen Transfer Reagents for Hydrogenation Reactions - The present invention relates to a process for reversible hydrogen storage, to a material for reversible hydrogen storage and to the use of the material for reversible hydrogen storage.07-08-2010
20100008860COLOR-MARKED OLIGOSACCHARIDES OR POLYSACCHARIDES - The invention concerns color-marked oligosaccharides or polysaccharides, procedures for the synthesis of these color-marked oligosaccharides or polysaccharides and their use in the determination of kidney function.01-14-2010
20090312348USE OF SODIUM BLOCKERS FOR AN EARLY THERAPY OF OBSTRUCTIVE LUNG DISEASES - The present invention relates to a blocker of sodium channels in cell membranes, particularly in membranes of epithelial cells of organs belonging to the respiratory tract to be used as the pharmaceutically active ingredient in a medicament for treating an obstructive lung disease in a patient.12-17-2009
20090291467Near Infrared Fluorophore for the Selective Labelling of Membranes in Cells - The present invention relates to anthraquinone derivatives which act as a fluorophore, to a process for producing said anthraquinone derivatives and their use as fluorophores for staining membranes in live or fixed cells.11-26-2009

Patent applications by UNIVERSITAT HEIDELBERG