| UNIVERSITAT DES SAARLANDES Patent applications |
| Patent application number | Title | Published |
|---|
| 20110245295 | BIOACTIVE PRE-TUBULYSINS AND USE THEREOF - The invention relates to bioactive pre-tubulysin derivatives, their preparation and pharmacological use. | 10-06-2011 |
| 20110159537 | SYNTHETIC PATHWAY ENZYMES FOR THE PRODUCTION OF ARGYRINS - The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes participating in the production of Argyrins, as well as genetically manipulated micro-organisms containing nucleic acid sequences encoding the synthetic pathway enzymes for the production of Argyrins, e.g. for inserting one or more of these coding sequences, mutating in a targeted manner one or more of these nucleic acid sequences, in a wild type producer micro-organism or in a heterologous micro-organism, for the production of Argyrins. | 06-30-2011 |
| 20110118241 | 6-Pyridin-3-YL-3,4-Dihydro-1H-Quinolin-2-One Derivatives and Related Compounds as Inhibitors of the Human Aldosterone Synthase CYP11B2 - The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and the use of these compounds and other heteroaryl substituted quinolinone derivatives for the treatment of hyperaldosteronism and/or disorders or diseases that are mediated by 11 β-hydroxylase (CYP11 B1). | 05-19-2011 |
| 20110112067 | Inhibitors of the Human Aldosterone Sythase CYP11B2 - The invention provides compounds of the general formula (I) | 05-12-2011 |
| 20110046147 | 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-RELATED DISEASES - The invention relates to 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) inhibitors, the preparation thereof and the use thereof for the treatment and prophylaxis of hormone-related, especially estrogen-related or androgen-related, diseases. | 02-24-2011 |
| 20100189605 | CELLS HAVING CAVITIES AND THE MANUFACTURE AND USE OF THE SAME - Cells having cavities and the manufacture and use of the same are described. An example cell includes a first layer including a gap to at least partially define a cavity and a reservoir area to receive material to enter the cavity by diffusion. Additionally, the cell includes one or more other layers coupled to the first layer to at least partially define the cavity and to hermetically seal the cavity from an exterior environment. | 07-29-2010 |
| 20090221591 | Selective Inhibitors of Human Corticosteroid Synthases - The invention relates to compounds for selectively inhibiting human corticosteroid synthases CYP1 1 B1 and CYP1 1 B2, and to the production and use thereof for treating hypercortisolism, diabetes mellitus, hyperaldosteronism, cardiac insufficiency, myocardial fibrosis, depression, age-related cognitive decline and metabolic syndrome. | 09-03-2009 |
| 20090105278 | Selective inhibitors of human corticosteroid syntheses - The invention relates to compounds for selectively inhibiting human corticosteroid syntheses CYP11B1 and CYP11B2, to the production thereof and to their use for treating hypercortisolism and diabetes mellitus or insufficiency of the heart and myocardial fibrosis. | 04-23-2009 |
