| UNIVERSITAT BERN Patent applications |
| Patent application number | Title | Published |
| 20110111967 | METHOD FOR OPTIMIZED ISOLATION OF RNA FROM FIXED TISSUE - In invention relates to a method for the isolation of RNA from tissue pretreated with formaldehyde comprising homogenizing the sample in the presence of a guanidinium salt in aqueous solution, and incubating the sample in the presence of 0.1 M to 5 M ammonium salt at a temperature between 50° C. and 100° C. The heat treatment in the presence of an ammonium salts demodifies RNA by reverting methylol groups which are formed in the presence of formaldehyde between amino groups in nucleobases of RNA and in basic amino acids, and by cleavage of methylene bridges between amino groups in nucleobases of RNA and basic amino acids, to provide high RNA recoveries and consistently high quality of RNA for further reaction, e.g. for reverse transcriptase-polymerase chain reaction or microarray analysis. | 05-12-2011 |
| 20110020475 | CARDIOPLEGIC SOLUTION - The present invention relates to a new cardioplegic solution to arrest and protect the heart muscle during surgery. The cardioplegic solution according to the invention offers several significant advantages as compared to standard available solutions, and contains magnesium sulfate heptahydrate, potassium chloride, procaine hydrochloride and xylitol. | 01-27-2011 |
| 20100212666 | System for Controlling Administration of Anaesthesia - A system for controlling administration of a respiratory depressant drug or mixture of drugs to a spontaneously breathing patient comprises a drug delivery unit ( | 08-26-2010 |
| 20100008895 | NOVEL EXOENZYME TOXIN OF AEROMONAS SALMONICIDA, AND USES THEREFOR - A protein toxin named | 01-14-2010 |
| 20090062401 | DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS - The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes. | 03-05-2009 |
| 20090012540 | Implant for Sealing and/or Healing a Defect in an Annulus of an Intervertebral Disc - An implant for sealing and/or healing a defect in an annulus having an area intended to encompass the defect. The implant is a textile strip that has a middle area which is intended to encompass the defect and which is an oriented low-density embroidered structure for guided tissue ingrowth and reinforcement and end areas adjacent to the middle area which are a high-density embroidered structure. | 01-08-2009 |
| 20080213535 | Oriented Zeolite Material and Method for Producing the Same - An oriented zeolite material comprises a plurality of zeolite crystals ( | 09-04-2008 |