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Universita Degli Studi di Trieste

Universita Degli Studi di Trieste Patent applications
Patent application numberTitlePublished
20110129536NANOCOMPOSITE MATERIALS BASED ON METALLIC NANOPARTICLES STABILIZED WITH BRANCHED POLYSACCHARIDES - The present invention provides nanocomposite systems made of metallic nanoparticles stabilized with branched cationic polysaccharides, in particular alditolic or aldonic mono- and oligo-saccharidic derivatives of chitosan, and their preparation obtainable with aqueous solutions of these polysaccharides in the presence or absence of reducing agents. The peculiar chemical and physical-chemical features of these polysaccharides allow to form metallic nanoparticles homogeneously dispersed in the polysaccharidic matrix and an effective stabilization thereof. The properties associated with the nanometric dimensions and the presence of biological signals on polymeric chains may be exploited in applications with antimicrobial activities and of molecular biosensors.06-02-2011
20090202640HYDROGELS OF POLYSACCHARIDE MIXTURES FOR TISSUE ENGINEERING AND AS CARRIERS OF ACTIVE COMPOUNDS - The present invention describes the preparation of hydrogels (or 3D matrices) obtainable from aqueous solutions of mixtures of acid polysaccharides and derivatives of basic polysaccharides, such as oligosaccharide derivatives of chitosan. Said solutions are suitably gelled with either chemical or physical gelling agents with the aim of encapsulating either cells, isolated or in multicellular associations, or pharmacologically active molecules, in solution or suspension, for use in the biomedical and pharmaceutical field.08-13-2009
20090197832POLYMER MIXTURES OF ANIONIC AND CATIONIC POLYSACCHARIDES AND USE THEREOF - Described in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behaviour with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behaviour renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery.08-06-2009