Universita Degli Studi Di Siena Patent applications |
Patent application number | Title | Published |
20130203831 | NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF - The present invention refers to compounds with inhibitory activity against 14-3-3 proteins and their use in the treatment of tumors, in particular chronic myeloid leukemia. The invention also provides methods for the identification of 14-3-3 protein inhibitors. | 08-08-2013 |
20110105365 | PRO-EPIL EXPRESSION LEVEL IN A BIOLOGICAL SAMPLE AS TESTICULAR CANCER BIOMARKER, PARTICULARLY IN COMBINATION WITH THE HCBETA AND AFP BIOMARKERS - The present invention is directed to the use of the expression level of the pro-EPIL gene as a biomarker for the diagnosing of testicular cancer, particularly a testicular germ cell tumor. The invention also relates to an in vitro method for detecting and/or classifying a testicular cancer in a subject comprising a step of determining the expression level of the gene encoding the pro-EPIL peptide in a biological, particularly in combination with the determination of the beta subunit HCGβ and the human alpha-fetoprotein AFP. The invention is also directed to a kit or solid support comprising nucleic acids or antibodies capable of determining the presence or the expression level of these three biological markers. | 05-05-2011 |
20110039854 | LINEAR AND CYCLIC GUANIDINE DERIVATIVES, METHOD OF PREPARATION AND USES THEREOF - The present invention relates to linear and cyclic guanidine derivatives, method of preparation and uses thereof, pharmaceutical compositions to be used as antifungal agents, in particular against | 02-17-2011 |
20100249152 | NEW 4-SUBSTITUTED DERIVATIVES OF PYRAZOLO[3,4-D PYRIMIDINE AND PYRROLO[2,3-D]PYRIMIDINE AND USES THEREOF - The present invention relates to a compound 4-substituted derivative of pyrazolo[3,4-d]pyrimidine or of pyrrolo[2,3-d]pyrimidine having the formula (I) and uses thereof, in particular for the treatment of bone related diseases and tumours. | 09-30-2010 |
20100197672 | PYRROLE COMPOUNDS AS INHIBITORS OF MYCOBACTERIA, SYNTHESIS THEREOF AND INTERMEDIATES THERETO - The present invention relates to a compound having the general formula (3): synthesis, intermediates and uses thereof. | 08-05-2010 |
20100173010 | Polymetaphosphate based formulations for therapy of microcrystalline arthropathies - Soluble pharmaceutical composition for the treatment of articular pathologies comprising an effective amount of a least one linear or cyclic polymetaphosphate or a soluble and pharmaceutically acceptable salt thereof, and appropriate diluents. | 07-08-2010 |
20100087445 | ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS - This invention provides novel aryl piperazine derivatives represented by Formula (I) having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D | 04-08-2010 |
20090238761 | Novel Aryl Piperazine Derivatives With Medical Utility - This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D | 09-24-2009 |
20080235030 | Automatic Method For Measuring a Baby's, Particularly a Newborn's, Cry, and Related Apparatus - The present invention concerns an automatic method for measuring a baby's cry, comprising the following step: A. having N samples ρ(i), for i=O, 1, . . . , (N−1), of an acoustic signal p(t) representing the cry, sampled at a sampling frequencŷ for a period of duration P; the method being characterised in that it assigns a score PainScore to the acoustic signal p(t) by means of a function AF of one or more acoustic parameters selected from the group comprising: —a root-mean-square or rms value prms of the acoustic signal p(t) in the period P; —a fundamental or pitch frequency F | 09-25-2008 |