| UNIVERSITA DEGLI STUDI DI ROMA "LA SAPIENZA" Patent applications |
| Patent application number | Title | Published |
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| 20120093879 | CARDIAC STEM CELLS AND USES OF SAME IN CARDIAC REPAIR - Method for the isolation, expansion and preservation of cardiac stem cells from human or animal tissue biopsy samples to be employed in cell transplantation and functional repair of the myocardium or other organs. Cells may also be used in gene therapy for treating cardiomyopathies, for treating ischemic heart diseases and for setting in vitro models to study drugs. | 04-19-2012 |
| 20120045421 | METHODS FOR THE ISOLATION OF CARDIAC STEM CELLS - Method for the isolation, expansion and preservation of cardiac stem cells from human or animal tissue biopsy samples to be employed in cell transplantation and functional repair of the myocardium or other organs. Cells may also be used in gene therapy for treating cardiomyopathies, for treating ischemic heart diseases and for setting in vitro models to study drugs. | 02-23-2012 |
| 20120021019 | CARDIAC STEM CELL POPULATIONS FOR REPAIR OF CARDIAC TISSUE - Method for the isolation, expansion and preservation of cardiac stem cells from human or animal tissue biopsy samples to be employed in cell transplantation and functional repair of the myocardium or other organs. Cells may also be used in gene therapy for treating cardiomyopathies, for treating ischemic heart diseases and for setting in vitro models to study drugs. | 01-26-2012 |
| 20120020935 | CARDIAC STEM CELLS AND METHODS FOR ISOLATION OF SAME - Method for the isolation, expansion and preservation of cardiac stem cells from human or animal tissue biopsy samples to be employed in cell transplantation and functional repair of the myocardium or other organs. Cells may also be used in gene therapy for treating cardiomyopathies, for treating ischemic heart diseases and for setting in vitro models to study drugs. | 01-26-2012 |
| 20110179714 | PROCESS FOR THE PURIFICATION-SWEETENING OF NATURAL GAS BY MEANS OF CONTROLLED DISSOCIATION OF HYDRATES AND USE THEREOF AS SEPARATORS - The invention concerns a process for reducing and/or removing sour gases, such as carbon dioxide and hydrogen sulfide, from natural gas or from gas associated with oil reservoirs, by means of the formation of mixed hydrates, wherein a selective separation is carried out both during the hydrates decomposition, under pressure conditions close to atmospheric pressure and temperatures little below zero, and, preferably, during a preliminary step, with pressures and temperatures close to the equilibrium values. | 07-28-2011 |
| 20110009468 | MIRNA, SIRNA AND USE THEREOF IN THERAPY - The present invention relates to a mixture of molecules comprising at least one miRNA and at least one siRNA, or at least two miRNAs, or at least two siRNAs for inducing hematopoietic differentiation or for treating leukemia wherein the miRNA is able to modulate hematopoietic differentiation and/or to act as oncosuppressor, and the siRNA is able to modulate hematopoietic differentiation or to inhibit the expression of a fusion product deriving from a chromosomic translocation associated to leukemia. | 01-13-2011 |
| 20100197672 | PYRROLE COMPOUNDS AS INHIBITORS OF MYCOBACTERIA, SYNTHESIS THEREOF AND INTERMEDIATES THERETO - The present invention relates to a compound having the general formula (3): synthesis, intermediates and uses thereof. | 08-05-2010 |
| 20100085122 | DEVICE WITH TWO DIFFERENTIAL OSCILLATORS WITH PULSED POWER SUPPLY COUPLED TO AND IN QUADRATURE-PHASE WITH EACH OTHER - The present invention concerns a device having a first and a second differential oscillators ( | 04-08-2010 |
| 20100038298 | HIGH-PERFORMANCE CHROMATOGRAPHIC COLUMNS CONTAINING ORGANIC OR COMPOSITE POLYMERIC MONOLITHIC SUPPORTS AND METHOD FOR THEIR PREPARATION - The invention concerns high-performance chromatographic columns containing polymeric monolithic supports with continuous bimodal porosity, suitable for the separation and/or purification of organic compounds of low, medium and high molecular weight, and bio-organic compounds such as peptides, proteins, oligo- and polynucleotides, oligo- and polysaccharides. The proposed columns include a hollow tubular support made of silica-based amorphous material or internally lined with such material, containing a monolithic stationary phase having a continuous, porous and rigid polymeric structure, wherein such stationary phase covalently bonds onto the internal walls of the said hollow tubular support. The chromatographic efficiency of the column is greater than 50,000 plates per metre. The invention also concerns methods for preparing such monolithic columns with gamma radiation-induced polymerization processes. | 02-18-2010 |
| 20100009938 | METHOD TO IDENTIFY AND TREAT SUBJECTS RESISTANT TO ACETYL SALICYLIC ACID - The invention relates to the use of acetyl salicylic acid (ASA) in combination with MRP4 channel inhibitors for the treatment of all diseases related to so-called ASA resistance. Particularly preferred among the MRP4 channel inhibitors is dipyridamole. The invention also relates to an in-vitro diagnostic method for identifying ASA-resistant patients and to the associated kit for implementing the diagnostic method. | 01-14-2010 |
| 20090317032 | Electro-Optical Tunable Filter and Manufacturing Process - An electro-optical filter made of a support in which an optical guide with a diffused channel waveguide and of a cover, that are created in borosilicate glass, and which includes a gap obtained by the use of suitable spacers, filled with a grating constituted of alternating strips of polymer and liquid crystal called POLICRYPS (Polymer Liquid CRYstal Polymer Slices), and with first electrodes that are coplanar to the support and next to the optical guide with a channel, that electrically control the grating making the filter tunable, and a manufacturing process. | 12-24-2009 |
| 20090312266 | PEPTIDE DERIVED FROM VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 BINDING INTEGRIN ALPHA5BETA1 HAVING PROANGIOGENIC ACTIVITY - Description of a sequence peptide isolated in the domain II type-immunoglobulin (Type-Ig) of the Vascular Endothelial Growth Factor receptor 1 (VEGF-1) binding integrin α5β1, usable for the preparation of pharmacological agents having proangiogenic activity. | 12-17-2009 |
| 20090036382 | TGF-Beta Modulators and Use Thereof - The present invention relates to molecules preferably of polypeptide nature with negative regulatory activity on the amount or activity of TGF-β through direct interaction with pro-TGF-β, and containing as active region a cysteine-rich polypeptide sequence defined as “EMI domain”, or its subfragments, wherein said “EMI domain” has at least 25% sequence homology to the ID NO2 sequence for pharmaceutical use. Even more preferably said polypeptide sequence consists of the EMI domain of the following proteins: emilin-1, emilin-2 and/or multimerin-2 or their subfragments having a length of at least 6 amino acids, capable of inhibiting the conversion of pro-TGFβ to mature TGFβ as anti-hypertensive drugs and polypeptides active on the cardiovascular system. The invention extends to the use of molecules which are known to negatively regulate TGF-β and to molecules which interfere with TGF-β binding to its receptors, or to inhibitors of TGF-β mRNA synthesis or TGF-β expression for the same therapeutic uses as anti-hypertensive drugs and polypeptides active on the cardiovascular system. | 02-05-2009 |
| 20080279840 | Histaminase of vegetable origin for use in the treatment of allergic and septic shock and of allergic asthma - A histaminase of vegetable origin to be used in the treatment of allergic and septic shock and in allergic asthma, and the preparation of the histaminase for pharmaceutical use and the corresponding pharmaceutical compositions. | 11-13-2008 |
| 20080218280 | Differential Oscillator Device with Pulsed Power Supply, and Related Driving Method - The present invention concerns a differential oscillator device, comprising resonant electronic means, capable to provide on at least two terminals at least one oscillating signal V | 09-11-2008 |
