| UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ Patent applications |
| Patent application number | Title | Published |
|---|
| 20120135134 | 1-HYDROXY-2-O-ACYL-SN-GLYCERO-3-PHOSPHOCHOLINE COMPOUNDS, PREPARATION PROCESS, ANTIFOULING COMPOSITION, PROCESS FOR ITS PREPARATION, METHOD TO PREVENT FOULING, METHOD TO TURN A SURFACE INTO AN ANTIFOULING SURFACE, AND, COVERED SURFACE - 1-OH-2-acyl-sn-glycero-3-phosphocholine compounds and its analogs, pure or mixed, having formula WCH2CHXCH2PO3YCH2CH2Z, where W is preferably a hydroxyl group or an O-acyl group containing from 2 to 22 carbon atoms, and where X is preferably an O-acyl group containing from 2 to 22 carbon atoms or a hydroxyl (OH) and where Y may be an (O | 05-31-2012 |
| 20110213153 | PROCESSES FOR THE PREPARATION OF PIPERIDINIC DERIVATIVES AND PHARMACEUTIC COMPOSITIONS CONTAINING THE SAME - Production processes for preparing pharmaceutical compositions containing new molecules capable of inhibiting acetylcholinesterase, thus being useful in the treatment of pathologies associated to cholinergic transmission, such as memory related disorders, neurodegenerative disorders such as Alzheimer's Disease, Miastenia Gravis or in the treatment of intoxications induced by chemical agents of central action. | 09-01-2011 |
| 20100324107 | USE OF PHTHALIMIDE AND/OR SULPHONAMIDE DERIVATIVES IN THE TREATMENT OF DISEASES WHICH REQUIRE REDUCING THE TNF-alpha LEVELS AND AN EXOGENOUS SOURCE OF NITRIC OXIDE, PHTHALIMIDE DERIVATIVES, SULPHONAMIDE DERIVATIVES, AND A METHOD FOR OBTAINING A SULPHONAMIDE DERIVATIVE - The present invention refers to the use of phthalimide and/or sulphonamide derivatives with nitric oxide donor properties, which have important activities in increasing the gamma-globin gene expression and anti-inflammatory and analgesic activities, effective in the treatment of hematologic diseases which require reducing the TNF-α levels and an exogenous source of nitric oxide. More particularly, the present invention describes the use of such phthalimide and/or sulphonamide derivatives for the treatment of sickle-cell disease. The invention also has as a novel characteristic the disclosure of new functionalized phthalimide derivatives designed from the prototypes thalidomide and hydroxyurea, and designed rationally through the strategy of molecular hybridization for the treatment of said diseases. The invention still discloses a new method for obtaining a specific sulphonamide derivative which can be used in the preparation of a drug for the treatment of diseases which require reducing the levels of the TNF-α factor and an exogenous source of nitric oxide. | 12-23-2010 |
