| UCL BUSINESS PLC Patent applications |
| Patent application number | Title | Published |
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| 20120134949 | POLYMERIC COLLAGEN BIOMATERIALS - This invention relates to the production of biomaterials from polymeric collagen (PC) and its seeding with cells and other components of biomaterials. Polymeric collagen is isolated from tissue, suspended in an acidic solution, and then neutralised at low temperature. The neutralised suspension is then seeded with biomaterial components, such as cells, and the polymeric collagen aggregated to form a biomaterial comprising the biomaterial components. Polymeric collagen biomaterials produced as described herein may therefore be useful in a range of tissue engineering applications. | 05-31-2012 |
| 20120115771 | CARRIER - A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition. | 05-10-2012 |
| 20120101301 | PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS - The present invention relates to a process for preparing a compound of formula wherein: R | 04-26-2012 |
| 20120084131 | Data communication system - The present invention relates to systems for communicating data. In particular, systems for communicating data to and from mobile devices are described. One system involves the use of a server to store the association between a shortcode and the data. A user device can be used to transmit the shortcode to a second user device. The second user device can then access the association at the server to access the data. The shortcode is transmitted via an audibly unique signal between the two devices. Further devices, systems, and methods for redeeming vouchers, transferring money, unlocking content on a device, and authenticating transactions all using audio are also disclosed. A method for managing data communication on a mobile device is further disclosed. In addition, a system for asynchronous transmission of the data is disclosed by use of reserving a shortcode at a server before the shortcode is associated with data. | 04-05-2012 |
| 20120077863 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS - A compound of formula I, or a pharmaceutically acceptable salt thereof, wherein —X | 03-29-2012 |
| 20120064290 | ARTICLE AND METHOD OF SURFACE TREATMENT OF AN ARTICLE - An article comprising: a substrate; and over at least part of a surface of said substrate an outer coating of hydroxyapatite and an intermediate bonding layer bonded to said substrate and to said outer coating, wherein a mechanical interlock is present between said substrate and said outer coating. | 03-15-2012 |
| 20120019316 | APPARATUS FOR DRIVING A RESONANT CIRCUIT - An apparatus for driving a resonant circuit is disclosed. The apparatus comprises: a first drive circuit, the first drive circuit arranged to provide a drive current to said resonant circuit; and a controller coupled to said first drive circuit, the first drive circuit further comprising: a first input adapted to receive a current from a power supply; a switch; a second input adapted to receive from said controller a signal to control said switch; an output coupled to said resonant circuit; a first inductor, which acts to set the drive current through said resonant circuit when the switch is closed; and a first diode coupled across said first inductor, said first diode arranged to enable current to continue to flow in the first inductor when the switch is open, wherein the controller is adapted to receive from a sensor a signal derived from the current flowing in said resonant circuit, wherein said sensor is coupled to said controller, and said controller is configured to close said switch to enable the drive current to flow through said resonant circuit when said signal derived from said sensor satisfies a first condition and said controller is further configured to open said switch to cause the drive current to stop flowing through the resonant circuit when said signal derived from said sensor satisfies a second condition. In a preferred embodiment, the apparatus also comprises a forward diode in series with the switch, so as to allow the resonance to be driven to a greater amplitude than otherwise possible. | 01-26-2012 |
| 20110308968 | METHOD FOR SEPARATING NANOMATERIALS - A method for dispersing nanomaterial comprising an electrochemical process, a solution of dispersed nanomaterial, comprising individual charged nanomaterial at a concentration of about O.1 mgm | 12-22-2011 |
| 20110287258 | METHOD FOR DISPERSING AND SEPARATING NANOTUBES - A method for dispersing nanotubes, comprising contacting the nanotubes with an electronic liquid comprising a metal and an amine solvent, a solution of dispersed nanotuhes, comprising individual nanotuhes at a concentration of greater than about 0.01 mgml | 11-24-2011 |
| 20110236464 | MEMBRANE - The invention relates to a membrane for supporting cells, especially RPE cells. The membrane is useful in the treatment of conditions such as age related macular degeneration. | 09-29-2011 |
| 20110206264 | IMAGE ANALYSIS SYSTEM AND/OR METHOD - Among other things, a method is disclosed comprising: receiving image data representing an image; processing the data to generate orientation information; processing the data using the orientation information to measure a quantity called local phase in a direction perpendicular to the orientation of a putative vessel; using the phase measurements from three collinear image locations or from two locations to detect the centerline of a symmetric image structure, such as a blood vessel, and to locate a center-point defined by the intersection of the centerline with the line created by the measurement locations. | 08-25-2011 |
| 20110178379 | TISSUE ASSESSMENT - A method of aiding in the diagnosis or prediction of degenerative joint disease in a joint of a patient. The method comprises obtaining a test spectrum of Raman scattered radiation from cartilage tissue in the joint, and analysing the test spectrum, or one or more regions thereof, to assess whether the test spectrum is consistent with the patient having, or subsequently developing, degenerative joint disease in the joint. | 07-21-2011 |
| 20110091217 | APPARATUS AND METHOD FOR TRANSPORTING MULTIPLE RADIO SIGNALS OVER OPTICAL FIBER - A method and apparatus for transporting three or more radio signals of the same frequency, such as multiple input multiple output (MIMO) radio signals, over optical fiber on a single optical carrier using a phase quadrature double sideband frequency translation technique is disclosed. | 04-21-2011 |
| 20110002912 | COMPOSITION - The present invention relates to a composition for improving stem cell integration. The present invention also relates to a method of improving stem cell integration and kits for improving stem cell integration. | 01-06-2011 |
| 20100297018 | Prognosis and therapy of liver failure - A method for assessing prognosis in an individual suffering from liver failure, which method comprises detecting endotoxin in the individual, for example by determining the neutrophil function in the individual. The method can be used to determine whether there is an increased risk of infection in the individual, an increased risk of organ failure in the individual, an increased risk of mortality in the individual and/or an increased risk that the individual will not respond positively to treatment with an immunosuppressive agent, a steroid or an antibiotic. | 11-25-2010 |
| 20100284922 | MARKER - The invention relates to the use of a cell death marker labelled with a wavelength-optimised label for identifying cell death in the eye. Suitable cell death markers are the Annexins and fragments and derivatives thereof. The invention also relates to a pharmaceutical composition comprising a cell death marker labelled with a wavelength-optimised label and a method for monitoring cell death in the eye using a cell death marker labelled with a wavelength-optimised label. | 11-11-2010 |
| 20100278896 | SOLID COMPOSITIONS - A solid, implantable dosage form comprising a therapeutically active agent in solid form, optionally with one or more pharmaceutically acceptable excipients, wherein the one or more excipients, when present, do not lead to a significant delay or prolongation of the release of active agent, as compared to an equivalent dosage form containing no excipients when tested in vitro. | 11-04-2010 |
| 20100278747 | CARRIER - The invention relates to a carrier for delivering agents to the posterior region of the eye, the carrier comprising a Vitamin E derivative, especially tocopherol. The carrier may also comprise a cell death marker, such as an annexin. | 11-04-2010 |
| 20100249925 | ARTICLE AND A METHOD OF SURFACE TREATMENT OF AN ARTICLE - A method of surface treatment of at least part of a surface of an implant, said method comprising: electrochemical deposition of a layer containing calcium and phosphorus ions onto a metallic substrate; and incorporation of a therapeutic agent into said electrochemically deposited layer and an implant so treated. | 09-30-2010 |
| 20100223258 | INFORMATION RETRIEVAL SYSTEM AND METHOD USING A BAYESIAN ALGORITHM BASED ON PROBABILISTIC SIMILARITY SCORES - An algorithm is provided which uses a model-based concept of a cluster and scores items using a score representative of the probability that a given item has been generated from the same distribution as one or more query items. The items are represented by a feature vector x | 09-02-2010 |
| 20100168067 | BIOMARKERS FOR BISPHOSPHONATE-RESPONSIVE BONE DISORDERS - This invention relates to the finding that the presence of polymorphisms in and around the farnesyl diphosphate synthase (FDPS) gene is predictive of the densitometric response of patients with bone disorders, such as osteoporosis, subsequent to commencing treatment with amino-bisphosphonates. Methods relating to the identification of individuals having bone disorders which are responsive to bisphosphonates and predicting the responsiveness of individuals with bone disorders to treatment with a bisphosphonate are provided. | 07-01-2010 |
| 20100069607 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS - A glycopeptide of the formula S-L-X—P, wherein: S is selected from an optionally protected monosaccharide, an optionally protected polysaccharide, a polyalkylene oxide chain and a group of the formula II, wherein R | 03-18-2010 |
| 20100069469 | FORMULATIONS AND COMPOSITES WITH REACTIVE FILLERS - The invention provides composite materials prepared by i) providing a fluid formulation comprising (1) at least one compound capable of polymerisation and/or cross-linking and (2) a water-consuming reactive filler; ii) optionally injecting said formulation into a site of use; iii) polymerising and/or cross-linking said compound, to form a solid polymer matrix (which may be degradable or non-degradable); iv) causing or allowing said filler to react with water absorbed by said polymer matrix, to produce a solid filler material which is dispersed throughout the composite material. The hydration and formation of the solid filler in situ provides desirable properties to the composites, which have utility for dental composites, bone fillers and adhesives and so on. The composite may also be used to release an active ingredient e.g. an antibacterial or DNA. | 03-18-2010 |
| 20100054415 | PHASE CONTRAST IMAGING - Phase contrast imaging is achieved using a sample mask | 03-04-2010 |
| 20100040632 | COMPOSITION - The present invention relates to a method of treating liver damage, especially hepatitis B virus (HBV) related liver damage. The present invention also relates to compositions and kits for use in treating liver damage. | 02-18-2010 |
| 20090215098 | QUANTIFICATION OF ENZYME ACTIVITY BY MASS SPECTROMETRY - The disclosure relates to methods of quantitatively analyzing the enzymatic activity of enzymes in samples containing a plurality of enzymes, using mass spectrometry. Isotopically labeled standards are employed. Purified enzymes and enzymes from crude cell lysates may be analyzed using the disclosed methods. As little as 0.02 pg of cell lysate may be detected. Also disclosed are kits for providing compositions so as to practice the disclosed methods. | 08-27-2009 |
| 20090184383 | PHOTODETECTOR - A semiconductor photodetector is disclosed which can have a high responsivity, high saturation power, and high bandwidth. The photodetector comprises a waveguide structure comprising: an active waveguide comprising an absorber for converting photons conveying an optical signal into charge carriers conveying a corresponding electrical signal; a carrier collection layer for transporting the charge carriers conveying the electrical signal; and a secondary waveguide immediately adjacent to the carrier collection layer, for receiving the photons to be detected, and which is evanescently coupled to the active waveguide. The secondary passive waveguide layer in the photodetector epitaxial structure enables the use of fast carrier transport material to generate high intrinsic bandwidth and travelling wave techniques associated with a scheme of evanescent coupling to increase the responsivity, saturated output power and bandwidth. This enables a detector with an ultra-thin absorption layer implying a high intrinsic bandwidth for the device. This can be combined with a travelling wave technique to overcome the limitation on the bandwidth due to the depletion capacitance, resulting in a high bandwidth, high responsivity, high power photodetector. | 07-23-2009 |
| 20090091325 | METHOD OF DETERMINING DAMAGE TO SKIN - The invention provides a method for determining the presence of high molecular weight molecules, aminoacid molecules or protein fragments, in human or other mammalian skin, comprising irradiating a sample of the said skin with light at one or more wavelengths present in solar radiation, in the presence of a spin-trapping agent for radicals of said molecules, and using comparative electron spin resonance (ESR) spectroscopy to determine or investigate the presence of radicals of the said molecules induced in the skin by the light. The method may be used to investigate a range of skin and other tissue damage and the efficacy of agents and methods intended to protect skin from damage. | 04-09-2009 |
