| TSUMURA & CO. Patent applications |
| Patent application number | Title | Published |
| 20120107426 | GHRELIN PRODUCTION PROMOTER - The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient. | 05-03-2012 |
| 20110111426 | METHOD OF BIOASSAYING YOKUKANSAN - The invention intends to find out a bioassay system with an in-vitro test capable of ensuring the higher quality of yokukansan, and provides a bioassay method for yokukansan, comprising competitively reacting a labeled ligand and yokukansan with cells or cell membranes expressing glutamate receptors, measuring the binding activity of yokukansan, and evaluating the pharmacological activity value of yokukansan from the measurement value. | 05-12-2011 |
| 20110039292 | BIOASSAY FOR YOKUKANSAN - Disclosed is a bioassay system in an in-vitro test that enables higher quality guarantee of yokukansan. A bioassay for yokukansan comprises the steps of culturing cells in a culture medium with serum, adding yokukansan to the cells in a serum-free medium, applying ER stress to the cells to induce cell death, and determining a pharmacological activity value of yokukansan from cell viability in the cells. | 02-17-2011 |
| 20110027821 | METHOD OF BIOASSAYING YOKUKANSAN - The invention intends to find out a bioassay system with an in-vitro test capable of ensuring the higher quality of yokukansan, and provides a bioassay method for yokukansan, comprising adding glutamate in an amount sufficient to induce cell death and yokukansan to a medium for culturing cells, and evaluating pharmacological activity value of yokukansan from viability of the cultured cells in the medium. | 02-03-2011 |
| 20100331270 | ADRENOMEDULLIN PRODUCTION ENHANCER - It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and/or a shogaol as active ingredients. | 12-30-2010 |
| 20100330210 | GHRELIN PRODUCTION PROMOTER - The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient. | 12-30-2010 |
| 20100317028 | BIOASSAY METHOD FOR YOKUKANSAN - The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound. | 12-16-2010 |
| 20100267029 | METHOD OF IDENTIFYING THE PLANT SPECIES OF THE GENUS UNCARIA - The present invention provides a method of identifying the plant species of the genus | 10-21-2010 |
| 20100210020 | METHOD FOR ANALYZING DITHIOCARBAMATE PESTICIDE USING MICROWAVE-ASSISTED THERMAL DIGESTION AND EXTRACTION - A method for analyzing a dithiocarbamate pesticide, which can ensure analytical precision with both ease and promptness is provided. The method for analyzing a dithiocarbamate pesticide comprises adding a crude drug, a preparation containing the same, or a treated product thereof, an aqueous acid catalyst solution, L-cysteine or a salt thereof, and an organic solvent for extraction to a reaction vessel, sealing the vessel, carrying out microwave irradiation, digesting a dithiocarbamate pesticide existing in the crude drug or the preparation containing the same into carbon disulfide, carrying out fractional extraction using the above organic solvent, and then analyzing the extract. | 08-19-2010 |
| 20100196944 | METHOD OF BIOASSAYING YOKUKANSAN - To find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, it is intended to provide a method of bioassaying yokukansan characterized by comprising adding a yokukansan-containing test sample to astroglial cells to be cultivated under the condition of thiamine deficiency, and then determining the pharmacological activity value of yokukansan based on the glutamic acid or neutral red intake level in the cultivated astroglial cells. | 08-05-2010 |
| 20100062515 | MICROBIAL CULTURE MEDIUM AND MICROBIAL CULTURE METHOD - There is provided a microbial culture medium and a microbial culture method for adequately growing a target bacterium contained in an antibacterial test sample. | 03-11-2010 |
| 20090181112 | TABLET COMPOSITION CONTAINING KAMPO EXTRACT - Provided is a tablet composition containing Kampo extract having more excellent disintegration and dissolution properties than ever before. The tablet composition containing Kampo extract contains a Kampo extract powder, croscarmellose sodium, and sodium hydrogen carbonate. The Kampo extract powder is preferably at least one extract powder selected from the group consisting of Kakkonto, Kakkontokasenkyushin'i, Shoseiryuto, Tokishakuyakusan, Kamishoyosan, Keishibukuryogan, Hochuekkito, Bofutushosan, Goshajinkigan, Maobushisaishinto, Keishikajutsubuto, Juzentaihoto, Sokeikakketsuto, Shakuyakukanzoto, Keishininjinto, Tokakujokito, Yokukansan, Goreisan, and Eppikajutsuto. | 07-16-2009 |
| 20090098228 | AGENT AND METHOD FOR IMPROVEMENT OF IMPAIRMENT OF LEARNING AND MEMORY - An improving agent for impairment of learning and memory containing yokukansan is provided as an easy and simple means for enhancing memory of aged people, etc. and for improving the impairment of learning and memory. | 04-16-2009 |
| 20090053334 | GHRELIN PRODUCTION PROMOTER - The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient. | 02-26-2009 |