| TOCAGEN INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120087894 | PRODUCER CELLS FOR REPLICATION COMPETENT RETROVIRAL VECTORS - The disclosure provide cell lines and methods for the production of vectors and viral particles useful in gene therapy. | 04-12-2012 |
| 20110287020 | RECOMBINANT VECTORS - This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders. | 11-24-2011 |
| 20110268720 | FORMULATIONS OF 5-FLUOROCYTOSINE AND USES THEREOF - The disclosure provides an extended release formulation of 5-fluorocytosine. In another aspect, a method of treating a fungal disease is provided. The method comprises administering to a subject in need thereof a fungus-treating effective amount of a composition comprising 5-fluorocytosine. In yet another aspect, a method of treating a cancer is provided. The method comprises administering to a subject in need thereof a sufficient amount of an expression vector to induce expression of cytosine deaminase which is capable of converting 5-fluorocytosine to 5-fluorourcail in cells of the cancer and a cancer-treating effective amount of a composition comprising 5-fluorocytosine. | 11-03-2011 |
| 20110217267 | GENE THERAPY VECTORS AND CYTOSINE DEAMINASES - This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders. | 09-08-2011 |
