THERMO FISHER SCIENTIFIC OY Patent applications |
Patent application number | Title | Published |
20160046980 | TRANSPOSON NUCLEIC ACIDS COMPRISING A CALIBRATION SEQUENCE FOR DNA SEQUENCING - Transposon nucleic acids comprising a transposon end sequence and a calibration sequence for DNA sequencing in the transposon end sequence. In one embodiment, the transposon end sequence is a Mu transposon end. A method for the generation of DNA fragmentation library based on a transposition reaction in the presence of a transposon end with the calibration sequence providing facilitated downstream handling of the produced DNA fragments, e.g., in the generation of sequencing templates. | 02-18-2016 |
20140334993 | Electronic Pipette - An electronic pipette comprising a piston actuated in a cylinder by a motor, a control system for carrying out pipette operations, and a user interface for operating the pipette, which user interface comprises a display, wherein the main menu of the user interface comprises a user defined shortcut to a specific pipetting application. | 11-13-2014 |
20140331794 | Electronic Pipette - An electronic pipette comprising a piston actuated in a cylinder by a motor, a control system for carrying out pipette operations, and a user interface for operating the pipette, wherein the user interface comprises features for defining at least one dilution variable for pipetting operations based on input pipetting operation variables of which one is dilution ratio. | 11-13-2014 |
20140273254 | METHOD, PRODUCT, AND SYSTEM FOR QUANTIFYING THE METHYLATION STATUS OF A NUCLEIC ACID IN A SAMPLE - Methods and systems are described for quantifying the methylation status of nucleic acids in a sample utilizing standardized curves derived from methylation-sensitive HRM data. The standardized curves are generated from HRM curves from a plurality of samples, each sample having a known but different methylation status. In one embodiment, the first negative derivative of each HRM curve from the known samples is plotted and a first value corresponding with a first melt peak and a second value corresponding with a second melt peak from the negative derivative plots are identified. The slope of a line connecting the first and second values for each sample is calculated and used to identify a slope data point that is plotted to generate the standardized curve. In another embodiment, a threshold line that intersects the plurality of HRM curves is generated and the standardized curve is generated from the intersection data points. | 09-18-2014 |
20140099658 | PARTICLE PROCESSING - The invention concerns a method for processing magnetic particles, which selectively interact with a substance present in a liquid medium. The particles are collected with a probe ( | 04-10-2014 |
20140056781 | SEALED PIPETTE - The invention relates to liquid dispensing and concerns a pipette comprising at least one aspiration channel with a piston. At the lower end of the aspiration channel there is an extension channel ( | 02-27-2014 |
20130338928 | METHODS AND SYSTEMS FOR HIGH RESOLUTION MELT ANALYSIS OF A NUCLEIC ACID SEQUENCE - Described herein are methods and systems for analyzing and visualizing HRM data from a double-stranded nucleic acid. The HRM data is generally characterized by a plurality of data points each including a signal value associated with the concentration of a double-stranded nucleic acid in a sample and a temperature value associated with a the temperature of the sample. Embodiments of the invention analyze the HRM curves from samples using the first negative derivative of the HRM curve or a virtual standard. The first negative derivative plot method may be used to identify the melting temperature of a homogenous double-stranded nucleic acid in a sample, as well as the presence and melting temperature of heterogeneous double-stranded nucleic acids in the sample. Data points associated with the melting temperature are plotted on a scatter plot for analysis. The virtual standard allows for visualization of HRM data across data sets. | 12-19-2013 |
20130295597 | AUTOMATED SYSTEM FOR SAMPLE PREPARATION AND ANALYSIS - A sample preparation and analysis system. The system | 11-07-2013 |
20130288355 | SYSTEM LAYOUT FOR AN AUTOMATED SYSTEM FOR SAMPLE PREPARATION AND ANALYSIS - A sample preparation and analysis system ( | 10-31-2013 |
20130209333 | REACTION VESSEL AND APPARATUS AND METHOD FOR OPENING AND CLOSING A REACTION VESSEL - A method and apparatus for opening a reaction vessel having a body forming a volume for liquid, and a lid. In the method at least one reaction vessel is placed on a transport vehicle and the reaction vessel is positioned on the vehicle so that the vessel's rotation about its own axis is prevented. Then, the at least one reaction vessel is transferred on the vehicle and a guide rod, attached to the lid that is attached by a hinge to the reaction vessel, is pushed by the movement of the vehicle against a guide surface that forces the lid to turn on the hinge so that the lid is at least partially opened. | 08-15-2013 |
20130209210 | METHOD AND ASSEMBLY FOR TRANSPORTING SINGLE AND MULTIPLE REACTION VESSELS - A method and apparatus for transporting single and multiple reaction vessels. At least one reaction vessel is provided and at least one tray includes at least two seats for the at least one reaction vessel, and at least one gripper. One of the reaction vessel or the tray is engaged with the gripper at a first position. The gripped element is transported to a second position wherein the gripper is released. A gripping collar is provided both on the reaction vessel and the tray for the gripper to engage. At one transport stage one of the reaction vessel or the tray is engaged with the gripper at a first position by pushing the gripper from above to engage with the gripping collar and in a second stage the transported element is disengaged from the gripper by moving the gripper sideways in relation to the center axis of the gripping collar. | 08-15-2013 |
20130203173 | Method for determining the concentration of beta-D-glucan - Method of selectively determining the concentration of beta-glucan in samples, in particular in liquid samples of cereal origin, and a kit for such analysis. The method comprises the steps of contacting of a beta-glucan containing sample and a dye in liquid phase, complexing the beta-glucan with the dye to provide a modified liquid phase, measuring photometrically the absorbance of the modified liquid phase, and determining the concentration of beta-glucan based on the absorbance of the modified liquid phase. According to the invention, the dye comprises a Calcofluor dye such as Calcofluor White or Calcofluor White M2R. It has been found that the same reagent, or reagent of the kind basic kind, gives the same result when the sample is measured using photometry as when the dye is used in a reaction wherein fluorescence is measured. | 08-08-2013 |
20130040403 | METHOD AND APPARATUS FOR AUTOMATED ANALYSIS - A method and apparatus for pretreatment of a desired sample in a discrete fluid analyzing instrument comprises automated means for handling and analyzing the sample and means for performing a pretreatment step on the sample or a sub-sample of the sample. The means for pretreatment are used for immobilizing at least one substance or analyte from the sample or sub-sample wherein the substance or analyte is reversibly immobilized. Usually, the apparatus further comprises means for eluting the substance or analyte from the capture means prior to analysis. | 02-14-2013 |
20130040307 | METHOD AND APPARATUS FOR AUTOMATED ANALYSIS - A method and apparatus for pretreatment of a sample of whole blood in a discrete fluid analyzing instrument comprises automated means for handling and analyzing the sample and means for performing a pretreatment step on the sample or a sub-sample of the sample. The means for pretreatment are used for immobilizing at least one substance or analyte from the sample or sub-sample wherein the substance or analyte is reversibly immobilized. Usually, the apparatus further comprises means for eluting the substance or analyte from the capture means prior to analysis. | 02-14-2013 |
20130030719 | METHODS AND SYSTEMS FOR IDENTIFYING THE QUANTITATION CYCLE FOR A PCR AMPLIFICATION REACTION - Methods and systems for identifying a quantitation cycle (C | 01-31-2013 |
20120121483 | MULTICHANNEL PIPETTE - The invention relates to liquid dispensing and concerns a multichannel pipette, which comprises on its lower tip a shelf in the transverse direction of the tip and to which lower tip a pipette tip can be attached, which pipette tip comprises at least one longitudinal claw, whereby when the pipette tip is in its place, the point of the claw is above the shelf. Each cylinder is connected with a claw opening comprising an opener so that by pressing the opener downwards the claws can be turned outwards off the shelf. The opening mechanism further comprises an organ resilient in the longitudinal direction. In accordance with the invention, the tip removal is made to function reliably, even if there were significant differences in the dimensioning of the opening constructions of the lower tips. | 05-17-2012 |
20110091986 | CHEMICAL ANALYSER, METHOD FOR SAMPLE-BASED ANALYSIS, DEVICE FOR HANDLING CUVETTES, AND LOADING METHOD - With the aid of the invention, a chemical analyser, a method for sample-based analysis, a device for handling cuvettes, and a loading method are provided. The chemical analyser ( | 04-21-2011 |
20110064543 | REACTION VESSEL AND METHOD FOR THE HANDLING THEREOF - A cuvette ( | 03-17-2011 |
20100143199 | PIPETTE TIP PACKAGE - The invention relates to a pipette by package, which has a plurality pipette tips in separate enclosures. The enclosures are securely closed by a joint lid. | 06-10-2010 |