The U.S. of America, as represented by the Secretary, Department of Health and Human Services
The U.S. of America, as represented by the Secretary, Department of Health and Human Services Patent applications | ||
Patent application number | Title | Published |
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20140147418 | AAV MEDIATED CTLA-4 GENE TRANSFER TO TREAT SJOGREN'S SYNDROME - The invention relates to a gene transfer-based method to protect a subject from Sjogren's syndrome. The method comprises administering to the subject an AAV virion comprising an AAV vector that encodes a soluble CTLA-4 (sCTLA-4) protein. Also provided are sCTLA-4 proteins and nucleic acid molecules that encode such sCTLA-4 proteins. Also provided are AAV vectors and AAV virions that encode a sCTLA-4 protein. | 05-29-2014 |
20100279950 | PEPTIDES OF A MELANOMA ANTIGEN AND THEIR USE IN DIAGNOSTIC, PROPHYLACTIC, AND THERAPEUTIC METHODS - Immunogenic peptides of a melanoma antigen recognized by T cells, designated gp100, bioassays using the peptides to diagnose, assess or prognose a mammal afflicted with cancer, more specifically melanoma or metastatic melanoma, and use of the proteins and peptides as immunogens to inhibit, prevent or treat melanoma. | 11-04-2010 |